Page last updated: 2024-11-04

linsidomine and Reperfusion Injury

linsidomine has been researched along with Reperfusion Injury in 14 studies

linsidomine: RN given refers to parent cpd; structure

Reperfusion Injury: Adverse functional, metabolic, or structural changes in tissues that result from the restoration of blood flow to the tissue (REPERFUSION) following ISCHEMIA.

Research Excerpts

ExcerptRelevanceReference
"Previous studies have suggested reductions in lung reperfusion injury with pentoxifylline, inositol polyanions, and the nitric oxide donor, SIN-1, but these agents have never been directly compared to ascertain which is superior."7.70Modulation of reperfusion injury after single lung transplantation by pentoxifylline, inositol polyanions, and sin-1. ( Clark, SC; Dark, JH; Flecknell, PA; Roughan, J; Sudarshan, C, 1999)
" The aim of our research was to compare molsidomine, SIN-1, SIN-1A, and lidocaine influence on arrhythmias and hemodynamic parameters in 2 experimental models in rats."3.85New approach to molsidomine active metabolites coming from the results of 2 models of experimental cardiology. ( Krzemiński, TF; Mitręga, KA; Porc, M; Żorniak, M, 2017)
"Previous studies have suggested reductions in lung reperfusion injury with pentoxifylline, inositol polyanions, and the nitric oxide donor, SIN-1, but these agents have never been directly compared to ascertain which is superior."3.70Modulation of reperfusion injury after single lung transplantation by pentoxifylline, inositol polyanions, and sin-1. ( Clark, SC; Dark, JH; Flecknell, PA; Roughan, J; Sudarshan, C, 1999)
"Ischemia-reperfusion injury causes tissue damage that leads to a decrease in bioavailability of nitric oxide."1.31The effects of the nitric oxide donor SIN-1 on ischemia-reperfused cutaneous and myocutaneous flaps. ( Kerrigan, CL; Khiabani, KT, 2002)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's7 (50.00)18.2507
2000's6 (42.86)29.6817
2010's1 (7.14)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Żorniak, M1
Mitręga, KA1
Porc, M1
Krzemiński, TF1
Yokozawa, T1
Rhyu, DY1
Cho, EJ1
Aoyagi, K1
Nielsen, VG1
Crow, JP1
Savoye, G1
Tamion, F1
Richard, V1
Varin, R1
Thuillez, C1
Kaundal, RK1
Shah, KK1
Sharma, SS1
Payne, D1
Kubes, P1
Lee, JJ1
Olmos, L1
Vanhoutte, PM1
Huang, YC1
Fisher, PW1
Nozik-Grayck, E1
Piantadosi, CA1
Yokoyama, I1
Hayashi, S1
Kobayashi, T1
Negita, M1
Namii, Y1
Katayama, A1
Nagasaka, T1
Koike, C1
Tachi, Y1
Hayakawa, A1
Tajiri, H1
Takagi, H1
Johnson, D2
Freischlag, JA2
Lesniak, R2
Kelly, H2
Mudaliar, JH2
Cambria, RA2
Seabrook, MD2
Towne, JB2
Clark, SC1
Sudarshan, C1
Roughan, J1
Flecknell, PA1
Dark, JH1
Lepore, DA1
Hurley, JV1
Stewart, AG1
Morrison, WA1
Anderson, RL1
Khiabani, KT1
Kerrigan, CL1

Other Studies

14 other studies available for linsidomine and Reperfusion Injury

ArticleYear
New approach to molsidomine active metabolites coming from the results of 2 models of experimental cardiology.
    Canadian journal of physiology and pharmacology, 2017, Volume: 95, Issue:2

    Topics: Animals; Anti-Asthmatic Agents; Arrhythmias, Cardiac; Creatine Kinase; Disease Models, Animal; Hemod

2017
Protective activity of (-)-epicatechin 3-O-gallate against peroxynitrite-mediated renal damage.
    Free radical research, 2003, Volume: 37, Issue:5

    Topics: Animals; Antioxidants; Caspases; Catechin; Cell Cycle; Cell Line; Cell Survival; DNA Fragmentation;

2003
Peroxynitrite decreases rabbit tissue factor activity in vitro.
    Anesthesia and analgesia, 2004, Volume: 98, Issue:3

    Topics: Animals; Blood Coagulation; Brain Chemistry; Humans; In Vitro Techniques; Molsidomine; Nitric Oxide

2004
Hemorrhagic shock resuscitation affects early and selective mesenteric artery endothelial function through a free radical-dependent mechanism.
    Shock (Augusta, Ga.), 2005, Volume: 23, Issue:5

    Topics: Acetylcholine; Animals; Blood Pressure; Dose-Response Relationship, Drug; Endothelium, Vascular; Fre

2005
Neuroprotective effects of NU1025, a PARP inhibitor in cerebral ischemia are mediated through reduction in NAD depletion and DNA fragmentation.
    Life sciences, 2006, Nov-10, Volume: 79, Issue:24

    Topics: Animals; Apoptosis; Brain; Brain Ischemia; Cell Survival; Disease Models, Animal; DNA Fragmentation;

2006
Nitric oxide donors reduce the rise in reperfusion-induced intestinal mucosal permeability.
    The American journal of physiology, 1993, Volume: 265, Issue:1 Pt 1

    Topics: Animals; Cats; Cyclic GMP; Intestinal Mucosa; Intestines; Ischemia; Molsidomine; Nitric Oxide; Nitro

1993
Recovery of endothelium-dependent relaxations four weeks after ischemia and progressive reperfusion in canine coronary arteries.
    Proceedings of the Association of American Physicians, 1996, Volume: 108, Issue:5

    Topics: Acetylcholine; Adenosine Diphosphate; Animals; Arteries; Bradykinin; Coronary Vessels; Dogs; Dose-Re

1996
Hypoxia compared with normoxia alters the effects of nitric oxide in ischemia-reperfusion lung injury.
    The American journal of physiology, 1997, Volume: 273, Issue:3 Pt 1

    Topics: Animals; Arginine; Blood Pressure; Hypoxia; In Vitro Techniques; Lung; Male; Microcirculation; Molsi

1997
Hepatocyte apoptosis and cytosolic calcium dynamics in ischemic injury.
    Transplantation proceedings, 1997, Volume: 29, Issue:8

    Topics: Animals; Apoptosis; Cells, Cultured; DNA Fragmentation; Ischemia; Liver; Mice; Mice, Inbred BALB C;

1997
Endothelial damage due to ischemia and reperfusion is prevented with SIN-1.
    Cardiovascular surgery (London, England), 1998, Volume: 6, Issue:4

    Topics: Animals; Endothelium, Vascular; Male; Molsidomine; Rabbits; Reperfusion Injury; Vasodilation; Vasodi

1998
Endothelial damage due to ischemia and reperfusion is prevented with SIN-1.
    Cardiovascular surgery (London, England), 1998, Volume: 6, Issue:5

    Topics: Animals; Endothelium, Vascular; Hindlimb; Male; Molsidomine; Rabbits; Reperfusion Injury; Sodium-Pot

1998
Modulation of reperfusion injury after single lung transplantation by pentoxifylline, inositol polyanions, and sin-1.
    The Journal of thoracic and cardiovascular surgery, 1999, Volume: 117, Issue:3

    Topics: Animals; Blood Platelets; Female; Free Radical Scavengers; Lung; Lung Transplantation; Malondialdehy

1999
Prior heat stress improves survival of ischemic-reperfused skeletal muscle in vivo.
    Muscle & nerve, 2000, Volume: 23, Issue:12

    Topics: Animals; Cell Survival; Cells, Cultured; Clone Cells; Heat-Shock Response; Hot Temperature; HSP70 He

2000
The effects of the nitric oxide donor SIN-1 on ischemia-reperfused cutaneous and myocutaneous flaps.
    Plastic and reconstructive surgery, 2002, Volume: 110, Issue:1

    Topics: Animals; Cell Survival; Female; Molsidomine; Neutrophils; Nitric Oxide Donors; Reperfusion Injury; S

2002