linsidomine has been researched along with Renal Insufficiency in 2 studies
linsidomine: RN given refers to parent cpd; structure
Renal Insufficiency: Conditions in which the KIDNEYS perform below the normal level in the ability to remove wastes, concentrate URINE, and maintain ELECTROLYTE BALANCE; BLOOD PRESSURE; and CALCIUM metabolism. Renal insufficiency can be classified by the degree of kidney damage (as measured by the level of PROTEINURIA) and reduction in GLOMERULAR FILTRATION RATE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pharmacokinetic measurements were performed in two groups of patients with coronary heart disease (CHD) after single and multiple dosing of 2 mg linsidomine (SIN 1)." | 9.07 | Pharmacokinetics of linsidomine (SIN 1) after single and multiple intravenous short infusions in patients with renal insufficiency. ( Degré, S; Gaertner, W; Ostrowski, J; Sennesael, J; Stolear, JC; Unger, P; Verbeelen, D; von Hattingberg, HM, 1993) |
| "Pharmacokinetic measurements were performed in two groups of patients with coronary heart disease (CHD) after single and multiple dosing of 2 mg linsidomine (SIN 1)." | 5.07 | Pharmacokinetics of linsidomine (SIN 1) after single and multiple intravenous short infusions in patients with renal insufficiency. ( Degré, S; Gaertner, W; Ostrowski, J; Sennesael, J; Stolear, JC; Unger, P; Verbeelen, D; von Hattingberg, HM, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Aoyagi, K | 1 |
| Sennesael, J | 1 |
| Verbeelen, D | 1 |
| Degré, S | 1 |
| Unger, P | 1 |
| Stolear, JC | 1 |
| Ostrowski, J | 1 |
| von Hattingberg, HM | 1 |
| Gaertner, W | 1 |
1 trial available for linsidomine and Renal Insufficiency
| Article | Year |
|---|---|
Pharmacokinetics of linsidomine (SIN 1) after single and multiple intravenous short infusions in patients with renal insufficiency.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Coronary Disease; Drug Admi | 1993 |
1 other study available for linsidomine and Renal Insufficiency
| Article | Year |
|---|---|
Inhibition of arginine synthesis by urea: a mechanism for arginine deficiency in renal failure which leads to increased hydroxyl radical generation.
Topics: Animals; Arginine; Cells, Cultured; Dose-Response Relationship, Drug; Guanidines; Hepatocytes; Hydro | 2003 |