linsidomine has been researched along with Myocardial Infarction in 13 studies
linsidomine: RN given refers to parent cpd; structure
Myocardial Infarction: NECROSIS of the MYOCARDIUM caused by an obstruction of the blood supply to the heart (CORONARY CIRCULATION).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Linsidomine is a direct donor of EDRF/NO which has an action on blood vessels (reduction of preload and dilatation of the large epicardial coronary vessels) and on platelets (inhibition of aggregation) without risk of tolerance." | 2.68 | [Linsidomine, direct donor of EDRF/NO: a new treatment for unstable angina]. ( Charansonney, O; Delonca, J; Giraud, T; Lennuyeux, E, 1996) |
| "In 28 patients with unstable angina pectoris biplane coronary angiography was performed in the acute stage." | 2.65 | [Dynamics of critical stenosis in patients with unstable angina pectoris]. ( Karsch, KR; Niemczyk, P; Seipel, L; Voelker, W, 1984) |
| "Allopurinol-treated hearts had significantly decreased nerve growth factor expression, which was substantially increased after coadministration of 3-morpholinosydnonimine." | 1.37 | Differential effects of NADPH oxidase and xanthine oxidase inhibition on sympathetic reinnervation in postinfarct rat hearts. ( Chen, CC; Hsu, YJ; Lee, TM, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (23.08) | 18.7374 |
| 1990's | 6 (46.15) | 18.2507 |
| 2000's | 2 (15.38) | 29.6817 |
| 2010's | 2 (15.38) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fan, Q | 1 |
| Yang, XC | 1 |
| Liu, Y | 1 |
| Wang, LF | 1 |
| Liu, SH | 1 |
| Ge, YG | 1 |
| Chen, ML | 1 |
| Wang, W | 1 |
| Zhang, LK | 1 |
| Irwin, MG | 1 |
| Xia, Z | 1 |
| Lee, TM | 1 |
| Chen, CC | 1 |
| Hsu, YJ | 1 |
| Karsch, KR | 1 |
| Niemczyk, P | 1 |
| Voelker, W | 1 |
| Seipel, L | 1 |
| Foucher-Lavergne, A | 1 |
| Kolsky, H | 1 |
| Spreux-Varoquaux, O | 1 |
| Delonca, J | 2 |
| Beaufils, P | 1 |
| Richard, V | 2 |
| Kaeffer, N | 2 |
| Tron, C | 2 |
| Thuillez, C | 2 |
| Blanc, T | 1 |
| Giraud, T | 1 |
| Lennuyeux, E | 1 |
| Charansonney, O | 1 |
| Aitchison, KA | 1 |
| Coker, SJ | 1 |
| Yamamoto, T | 1 |
| Bing, RJ | 1 |
| Maunoury, C | 1 |
| Sébahoun, S | 1 |
| Le Feuvre, C | 1 |
| Antonietti, T | 1 |
| Barritault, L | 1 |
| Wautier, JL | 1 |
| Degré, S | 1 |
| Sobolski, J | 1 |
| Berkenboom, G | 1 |
| Abramowicz, M | 1 |
| Vandermoten, P | 1 |
| Stoupel, E | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Randomized, Single-blinded Placebo-controlled Trial of Ischemic Preconditioning in Raynaud's Phenomenon (RP)[NCT02506062] | 21 participants (Actual) | Interventional | 2015-07-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for linsidomine and Myocardial Infarction
| Article | Year |
|---|---|
Nitric oxide donors.
Topics: Animals; Aspirin; Drug Tolerance; Heart; Humans; In Vitro Techniques; Molsidomine; Myocardial Infarc | 2000 |
[Role of molsidomine on platelet activation in coronary ischemia].
Topics: Angina Pectoris; Angina, Unstable; Humans; Molsidomine; Myocardial Infarction; Platelet Aggregation | 1988 |
5 trials available for linsidomine and Myocardial Infarction
| Article | Year |
|---|---|
Postconditioning attenuates myocardial injury by reducing nitro-oxidative stress in vivo in rats and in humans.
Topics: Aged; Angioplasty, Balloon, Coronary; Animals; Apoptosis; Disease Models, Animal; Dose-Response Rela | 2011 |
[Dynamics of critical stenosis in patients with unstable angina pectoris].
Topics: Angina Pectoris; Angina, Unstable; Coronary Angiography; Coronary Circulation; Coronary Disease; Hem | 1984 |
Hemodynamics, tolerability, and pharmacokinetics of linsidomine (SIN-1) infusion during the acute phase of uncomplicated myocardial infarction.
Topics: Adult; Aged; Blood Pressure; Cardiac Output; Female; Heart Rate; Hemodynamics; Humans; Infusions, In | 1993 |
The ESPRIM trial: short-term treatment of acute myocardial infarction with molsidomine. European Study of Prevention of Infarct with Molsidomine (ESPRIM) Group.
Topics: Administration, Oral; Double-Blind Method; Female; Hospital Mortality; Humans; Infusions, Intravenou | 1994 |
[Linsidomine, direct donor of EDRF/NO: a new treatment for unstable angina].
Topics: Adult; Aged; Angina, Unstable; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug | 1996 |
6 other studies available for linsidomine and Myocardial Infarction
| Article | Year |
|---|---|
Differential effects of NADPH oxidase and xanthine oxidase inhibition on sympathetic reinnervation in postinfarct rat hearts.
Topics: Acetophenones; Allopurinol; Animals; Arrhythmias, Cardiac; Coronary Vessels; Ethidium; Male; Molsido | 2011 |
Ischemic preconditioning protects against coronary endothelial dysfunction induced by ischemia and reperfusion.
Topics: Acetylcholine; Animals; Arginine; Calcimycin; Coronary Vessels; Endothelium, Vascular; Male; Molsido | 1994 |
Myocardial and coronary endothelial protective effects of acetylcholine after myocardial ischaemia and reperfusion in rats: role of nitric oxide.
Topics: Acetylcholine; Animals; Arginine; Blood Pressure; Coronary Vessels; Disease Models, Animal; Endothel | 1995 |
Potential interactions between iloprost and SIN-1 on platelet aggregation and myocardial infarct size in vivo.
Topics: Animals; Arrhythmias, Cardiac; Creatine Kinase; Drug Synergism; Electrocardiography; Hemodynamics; I | 1999 |
Value of linsidomin in assessing myocardial viability with thallium-201 SPECT.
Topics: Aged; Cell Survival; Female; Heart; Humans; Image Processing, Computer-Assisted; Male; Middle Aged; | 2001 |
Comparison of the influence of nitrates, molsidomine and SIN-1, a molsidomine metabolite in acute coronary insufficiency.
Topics: Coronary Circulation; Coronary Vasospasm; Coronary Vessels; Ergonovine; Humans; Molsidomine; Myocard | 1985 |