linsidomine has been researched along with Muscle Relaxation in 78 studies
linsidomine: RN given refers to parent cpd; structure
Muscle Relaxation: That phase of a muscle twitch during which a muscle returns to a resting position.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To explore endothelium-dependent relaxation and the L-arginine (L-ARG)-nitric oxide (NO) pathway during chronic hypoxia, we examined isolated rings from large conduit pulmonary arteries and aorta from rats exposed to either room air (N), 3-week hypoxia (H), or 3-week H followed by 72-h recovery to normoxia (room air)." | 7.68 | Loss of endothelium-dependent relaxation in proximal pulmonary arteries from rats exposed to chronic hypoxia: effects of in vivo and in vitro supplementation with L-arginine. ( Adnot, S; Blouquit, Y; Carville, C; Eddahibi, S; Raffestin, B, 1993) |
| "To explore endothelium-dependent relaxation and the L-arginine (L-ARG)-nitric oxide (NO) pathway during chronic hypoxia, we examined isolated rings from large conduit pulmonary arteries and aorta from rats exposed to either room air (N), 3-week hypoxia (H), or 3-week H followed by 72-h recovery to normoxia (room air)." | 3.68 | Loss of endothelium-dependent relaxation in proximal pulmonary arteries from rats exposed to chronic hypoxia: effects of in vivo and in vitro supplementation with L-arginine. ( Adnot, S; Blouquit, Y; Carville, C; Eddahibi, S; Raffestin, B, 1993) |
| "Acute esophagitis was induced by perfusion with 0." | 1.34 | Cyclic AMP dependent down regulation in the relaxation of smooth muscle cells of cat esophagitis. ( Je, HD; Lee, YP; Shin, CY; Sohn, UD; Song, HJ, 2007) |
| " ODQ (1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one), a potent and selective inhibitor of soluble guanylyl cyclase (sGC), did not significantly affect relaxant actions of ONOO-, but ODQ markedly attenuated SIN-1-elicited relaxation with a rightward shift in the dose-response curve and an unaltered maximal response." | 1.31 | Comparative vasodilation of peroxynitrite and 3-morpholinosydnonimine. ( Trakranrungsie, N; Will, JA, 2001) |
| " Nitroglycerin pre-exposure (10 microM for 30 min) provoked a significant shift to the right of the dose-response curve to nitroglycerin in aortae isolated from rats of 8 weeks, 12 and 18 months." | 1.29 | Nitrate tolerance and aging in isolated rat aorta. ( Berkenboom, G; Brékine, D; Fontaine, J; Unger, P, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (6.41) | 18.7374 |
| 1990's | 56 (71.79) | 18.2507 |
| 2000's | 16 (20.51) | 29.6817 |
| 2010's | 1 (1.28) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sarac, B | 1 |
| Durmus, N | 1 |
| Bagcivan, I | 1 |
| Altun, A | 1 |
| Turan, M | 1 |
| Sencan, M | 1 |
| Rabelo, LA | 1 |
| Cortes, SF | 2 |
| Alvarez-Leite, JI | 1 |
| Lemos, VS | 2 |
| Aldini, G | 1 |
| Carini, M | 1 |
| Piccoli, A | 1 |
| Rossoni, G | 1 |
| Facino, RM | 1 |
| Jun, CH | 1 |
| Lee, TS | 1 |
| Sohn, UD | 2 |
| Tuncel, BI | 1 |
| Sadan, G | 1 |
| Elmedal Laursen, B | 1 |
| Mulvany, MJ | 3 |
| Simonsen, U | 3 |
| Shin, CY | 1 |
| Lee, YP | 1 |
| Song, HJ | 1 |
| Je, HD | 1 |
| Klockenbusch, W | 1 |
| Schrör, K | 2 |
| Schini, VB | 3 |
| Bond, R | 1 |
| Gao, Y | 1 |
| Illiano, S | 1 |
| Junquero, DC | 1 |
| Mombouli, JV | 1 |
| Nagao, T | 2 |
| Smart, F | 1 |
| Vanhoutte, PM | 9 |
| Carville, C | 1 |
| Raffestin, B | 1 |
| Eddahibi, S | 1 |
| Blouquit, Y | 1 |
| Adnot, S | 1 |
| Ellis, JL | 3 |
| Conanan, ND | 1 |
| Schini-Kerth, V | 1 |
| Bara, A | 1 |
| Mülsch, A | 1 |
| Busse, R | 1 |
| Kienbaum, P | 1 |
| Braun, M | 1 |
| Hohlfeld, T | 1 |
| Weber, AA | 1 |
| Sarbia, M | 1 |
| Murphy, ME | 1 |
| Brayden, JE | 1 |
| Hempelmann, RG | 1 |
| Papadopoulos, I | 1 |
| Herzig, S | 1 |
| Kenny, D | 1 |
| Coughlan, MG | 1 |
| Kampine, JP | 1 |
| Montgomery, RR | 1 |
| Bosnjak, ZJ | 1 |
| Warltier, DC | 1 |
| Stuart-Smith, K | 1 |
| Bynoe, TC | 1 |
| Lindeman, KS | 1 |
| Hirshman, CA | 1 |
| Bialecki, RA | 1 |
| Stinson-Fisher, C | 1 |
| Fernandes, LB | 1 |
| Undem, BJ | 3 |
| Unger, P | 2 |
| Berkenboom, G | 2 |
| Brékine, D | 1 |
| Fontaine, J | 2 |
| Jones, KA | 1 |
| Lorenz, RR | 1 |
| Warner, DO | 1 |
| Katusić, ZS | 2 |
| Sieck, GC | 1 |
| Meyer, P | 1 |
| Flammer, J | 1 |
| Lüscher, TF | 1 |
| Meyer, MF | 1 |
| Taher, A | 1 |
| Krah, H | 1 |
| Staubesand, J | 1 |
| Becker, AJ | 2 |
| Kircher, M | 1 |
| Mayer, B | 1 |
| Jonas, U | 3 |
| Forssmann, WG | 1 |
| Stief, CG | 3 |
| De Man, JG | 1 |
| Boeckxstaens, GE | 1 |
| De Winter, BY | 1 |
| Moreels, TG | 1 |
| Herman, AG | 1 |
| Pelckmans, PA | 1 |
| Marks, GS | 2 |
| McLaughlin, BE | 1 |
| Jimmo, SL | 1 |
| Poklewska-Koziell, M | 1 |
| Brien, JF | 2 |
| Nakatsu, K | 2 |
| Martins, SL | 1 |
| De Oliveira, RB | 1 |
| Ballejo, G | 1 |
| Waldeck, K | 1 |
| Persson, K | 2 |
| Andersson, KE | 3 |
| Yang, XP | 1 |
| Wang, FX | 1 |
| Ren, DC | 1 |
| Lu, SC | 1 |
| Fu, SX | 1 |
| Li, YS | 1 |
| Hussain, AS | 1 |
| Desta, B | 1 |
| Nakashima, M | 1 |
| Boulanger, CM | 1 |
| Lee, JJ | 1 |
| Olmos, L | 1 |
| Canning, BJ | 1 |
| Karakousis, PC | 1 |
| Dey, RD | 1 |
| Plane, F | 3 |
| Hurrell, A | 1 |
| Jeremy, JY | 2 |
| Garland, CJ | 3 |
| Uckert, S | 1 |
| Truss, MC | 2 |
| Machtens, S | 1 |
| Schultheiss, D | 1 |
| Matsumoto, T | 1 |
| Takahashi, M | 1 |
| Omura, T | 1 |
| Takaoka, A | 1 |
| Liu, Q | 1 |
| Nakae, I | 1 |
| Kinoshita, M | 1 |
| Hosoki, R | 1 |
| Matsuki, N | 1 |
| Kimura, H | 1 |
| Pérez Vallina, JR | 1 |
| Menéndez Antolin, L | 1 |
| Cantabrana, B | 1 |
| Sánchez, M | 1 |
| Hidalgo, A | 1 |
| Hernández, M | 1 |
| Elmedal, B | 1 |
| Wiley, KE | 1 |
| Cohen, RA | 1 |
| Zygmunt, PM | 1 |
| Paulsson, M | 1 |
| Högestätt, ED | 1 |
| Zhang, XF | 1 |
| Komuro, T | 1 |
| Miwa, S | 1 |
| Minowa, T | 1 |
| Iwamuro, Y | 1 |
| Okamoto, Y | 1 |
| Ninomiya, H | 1 |
| Sawamura, T | 1 |
| Masaki, T | 1 |
| Petkov, GV | 1 |
| Spassov, GD | 1 |
| Boev, KK | 1 |
| Hosoda, K | 1 |
| Takahashi, T | 1 |
| Fujino, MA | 1 |
| Owyang, C | 1 |
| Huber, A | 1 |
| Trudrung, P | 1 |
| Storr, M | 1 |
| Franck, H | 1 |
| Schusdziarra, V | 1 |
| Ruth, P | 1 |
| Allescher, HD | 1 |
| Chataigneau, T | 1 |
| Félétou, M | 1 |
| Huang, PL | 1 |
| Fishman, MC | 1 |
| Duhault, J | 1 |
| Wadsworth, RM | 1 |
| Buus, NH | 1 |
| Fusi, F | 1 |
| Valoti, M | 1 |
| Frosini, M | 1 |
| Sgaragli, GP | 1 |
| Wu, CC | 1 |
| Chen, SJ | 1 |
| Yen, MH | 1 |
| Freitas, MR | 1 |
| Muller, B | 1 |
| Lino, YD | 1 |
| Queiroga, CE | 1 |
| Dick, JM | 1 |
| Van Geldre, LA | 1 |
| Timmermans, JP | 1 |
| Lefebvre, RA | 1 |
| Ny, L | 1 |
| Pfeifer, A | 1 |
| Aszòdi, A | 1 |
| Ahmad, M | 1 |
| Alm, P | 1 |
| Hedlund, P | 1 |
| Fässler, R | 1 |
| Fujiwara, M | 1 |
| Andersson, K | 1 |
| Park, KH | 1 |
| Kim, KH | 1 |
| Choi, MS | 1 |
| Choi, SH | 1 |
| Yoon, JM | 1 |
| Kim, YG | 1 |
| Lee, WC | 1 |
| Jeng, LB | 1 |
| Lin, PJ | 1 |
| Chu, Y | 1 |
| Hung, CM | 1 |
| Yu, MC | 1 |
| Chang, CC | 1 |
| Tanović, A | 1 |
| Jiménez, M | 1 |
| Fernández, E | 1 |
| Buxton, IL | 2 |
| Kaiser, RA | 1 |
| Malmquist, NA | 2 |
| Tichenor, S | 2 |
| Trakranrungsie, N | 1 |
| Will, JA | 1 |
| Hashitani, H | 1 |
| Fukuta, H | 1 |
| Dickens, EJ | 1 |
| Suzuki, H | 1 |
| Holzmann, S | 3 |
| Kukovetz, WR | 4 |
| Braida, C | 1 |
| Pöch, G | 1 |
| Holmquist, F | 1 |
| Hedlund, H | 1 |
| Yeates, RA | 1 |
| Schmid, M | 1 |
| Komori, K | 1 |
| Gloviczki, P | 1 |
| Bourchier, RG | 1 |
| Henry, PJ | 1 |
| Horowitz, JD | 1 |
| Louis, WJ | 1 |
| Fang, ZY | 1 |
| Dembinska-Kiec, A | 1 |
| Pallapies, D | 1 |
| Simmet, T | 1 |
| Peskar, BM | 1 |
| Peskar, BA | 1 |
| Siegfried, MR | 1 |
| Erhardt, J | 1 |
| Rider, T | 1 |
| Ma, XL | 1 |
| Lefer, AM | 1 |
| Maurice, DH | 1 |
| Crankshaw, D | 1 |
| Haslam, RJ | 1 |
| Yousif, MH | 1 |
| Yousif, F | 1 |
| Thulesius, O | 1 |
| Miller, VM | 1 |
| Schmidt, K | 1 |
1 review available for linsidomine and Muscle Relaxation
| Article | Year |
|---|---|
[Pharmacological therapy in erectile dysfunction--current standards and new viewpoint].
Topics: Alprostadil; Dosage Forms; Enzyme Inhibitors; Erectile Dysfunction; Humans; Male; Molsidomine; Muscl | 1997 |
77 other studies available for linsidomine and Muscle Relaxation
| Article | Year |
|---|---|
Investigation of relaxant effects of new agents affecting nitric oxide/cyclic guanosine monophosphate pathway on sheep oddi sphincter.
Topics: Animals; Carbachol; Cyclic GMP; Dose-Response Relationship, Drug; Guanylate Cyclase; In Vitro Techni | 2010 |
Endothelium dysfunction in LDL receptor knockout mice: a role for H2O2.
Topics: Acetylcholine; Amitrole; Animals; Aorta, Thoracic; Arteriosclerosis; Catalase; Endothelium; Endothel | 2003 |
Procyanidins from grape seeds protect endothelial cells from peroxynitrite damage and enhance endothelium-dependent relaxation in human artery: new evidences for cardio-protection.
Topics: 6-Ketoprostaglandin F1 alpha; Antioxidants; Biflavonoids; Catechin; Cell Survival; Cells, Cultured; | 2003 |
NO/cyclic GMP pathway mediates the relaxation of feline lower oesophageal sphincter.
Topics: Aminoquinolines; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cats; Cyclic GMP; Dose-Response R | 2003 |
Effects of phosphodiesterase V inhibition on nitric oxide-mediated relaxation responses in guinea pig trachea.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Arginine; Cyclic Nucleotide Phosphodiesterases, Type 5 | 2004 |
Involvement of guanylyl cyclase, protein kinase A and Na+ K+ ATPase in relaxations of bovine isolated bronchioles induced by GEA 3175, an NO donor.
Topics: Animals; Bronchi; Calcium; Cattle; Colforsin; Cyclic AMP; Cyclic GMP; Cyclic GMP-Dependent Protein K | 2006 |
Cyclic AMP dependent down regulation in the relaxation of smooth muscle cells of cat esophagitis.
Topics: Adenylyl Cyclases; Animals; Blotting, Western; Bucladesine; Cats; Cell Membrane Permeability; Colfor | 2007 |
Prostacyclin contributes to nitroglycerin-mediated relaxation of human umbilical arteries.
Topics: Epoprostenol; Female; Humans; In Vitro Techniques; Indomethacin; Molsidomine; Muscle Relaxation; Mus | 1993 |
The sydnonimine C87-3754 evokes endothelium-independent relaxations and prevents endothelium-dependent contractions in blood vessels of the dog.
Topics: Animals; Dinoprost; Dogs; Drug Interactions; Electrophysiology; Endothelium, Vascular; Female; Male; | 1993 |
Loss of endothelium-dependent relaxation in proximal pulmonary arteries from rats exposed to chronic hypoxia: effects of in vivo and in vitro supplementation with L-arginine.
Topics: Acetylcholine; Animals; Arginine; Calcimycin; Endothelins; Endothelium, Vascular; Hypoxia; In Vitro | 1993 |
Effect of potassium channel blockers on relaxations to a nitric oxide donor and to nonadrenergic nerve stimulation in guinea pig trachea.
Topics: Animals; Arginine; Charybdotoxin; Dose-Response Relationship, Drug; Electric Stimulation; Guinea Pig | 1994 |
Pyrrolidine dithiocarbamate selectively prevents the expression of the inducible nitric oxide synthase in the rat aorta.
Topics: Acetylcholine; Amino Acid Oxidoreductases; Analysis of Variance; Animals; Antioxidants; Aorta, Thora | 1994 |
Antiatherosclerotic effects of oral naftidrofuryl in cholesterol-fed rabbits involve inhibition of neutrophil function.
Topics: Acetylcholine; Administration, Oral; Animals; Aorta, Abdominal; Aorta, Thoracic; Arteriosclerosis; C | 1995 |
Nitric oxide hyperpolarizes rabbit mesenteric arteries via ATP-sensitive potassium channels.
Topics: Adenosine Triphosphate; Animals; Biological Factors; Glyburide; In Vitro Techniques; Membrane Potent | 1995 |
Non-synergistic relaxant effects of vasoactive intestinal polypeptide and SIN-1 in human isolated cavernous artery and corpus cavernosum.
Topics: Arteries; Drug Interactions; Humans; In Vitro Techniques; Isometric Contraction; Male; Molsidomine; | 1995 |
Cultured endothelial cells restore vasodilator responses to coronary arteries with impaired endothelial function and alter the response to a nitric oxide donor.
Topics: Animals; Arginine; Blood Flow Velocity; Calcimycin; Cells, Cultured; Coronary Circulation; Coronary | 1994 |
Differential effects of nitrovasodilators and nitric oxide on porcine tracheal and bronchial muscle in vitro.
Topics: Animals; Bronchi; Bronchoconstriction; Female; Hemoglobins; In Vitro Techniques; Male; Methylene Blu | 1994 |
KCa channel antagonists reduce NO donor-mediated relaxation of vascular and tracheal smooth muscle.
Topics: Animals; Calcium; Cyclic GMP; Guinea Pigs; In Vitro Techniques; Male; Molsidomine; Muscle Relaxation | 1995 |
Potentiation of nonadrenergic noncholinergic relaxation of human isolated bronchus by selective inhibitors of phosphodiesterase isozymes.
Topics: Atropine; Bronchi; Colforsin; Electric Stimulation; Histamine; Humans; In Vitro Techniques; Indometh | 1994 |
Nitrate tolerance and aging in isolated rat aorta.
Topics: Aging; Animals; Aorta, Thoracic; Dose-Response Relationship, Drug; Drug Tolerance; In Vitro Techniqu | 1993 |
Changes in cytosolic cGMP and calcium in airway smooth muscle relaxed by 3-morpholinosydnonimine.
Topics: Animals; Calcium; Cyclic AMP; Cyclic GMP; Cytosol; Dogs; Female; In Vitro Techniques; Male; Methylen | 1994 |
Local anesthetic drugs reduce endothelium-dependent relaxations of porcine ciliary arteries.
Topics: Anesthetics, Local; Animals; Arginine; Arteries; Ciliary Body; Endothelium, Vascular; Isometric Cont | 1993 |
Intracavernous application of SIN-I in rabbit and man: functional and toxicological results.
Topics: Animals; Blood Pressure; Culture Techniques; Dose-Response Relationship, Drug; Humans; Isometric Con | 1993 |
Inhibition of non-adrenergic non-cholinergic relaxations by nitric oxide donors.
Topics: Animals; Autonomic Nervous System; Electric Stimulation; Feedback; Gastric Fundus; In Vitro Techniqu | 1995 |
Time-dependent increase in nitric oxide formation concurrent with vasodilation induced by sodium nitroprusside, 3-morpholinosydnonimine, and S-nitroso-N-acetylpenicillamine but not by glyceryl trinitrate.
Topics: Animals; Aorta, Thoracic; In Vitro Techniques; Luminescent Measurements; Male; Molsidomine; Muscle R | 1995 |
Rat duodenum nitrergic-induced relaxations are cGMP-independent and apamin-sensitive.
Topics: 4-Aminopyridine; Animals; Apamin; Cyclic GMP; Cystamine; Duodenum; Hydroxylamines; In Vitro Techniqu | 1995 |
Effects of KRN2391, a novel vasodilator acting as a nitrate and a K+ channel opener, on the rabbit lower urinary tract.
Topics: Animals; Benzopyrans; Cromakalim; Cyclic GMP; Electrophysiology; Female; Hypoglycemic Agents; Molsid | 1995 |
Effects of 3-morpholinosydnonimine-N-ethylcarbamide on hypoxia-induced mechanical and electric responses of isolated pig coronary artery.
Topics: Animals; Coronary Vessels; Hypoxia; In Vitro Techniques; Membrane Potentials; Molsidomine; Muscle Re | 1995 |
Superoxide does not inhibit glyceryl trinitrate-rabbit aortic strip-mediated relaxation of rabbit Taenia coli. Evidence against a role for nitric oxide itself as the smooth muscle active drug metabolite?
Topics: Animals; Aorta, Thoracic; Biotransformation; In Vitro Techniques; Male; Molsidomine; Muscle Relaxati | 1996 |
The nitrate ester ITF 296 relaxes isolated canine arteries and veins.
Topics: Animals; Arteries; Benzoxazines; Dogs; Electrophysiology; Endothelium, Vascular; Female; In Vitro Te | 1995 |
Recovery of endothelium-dependent relaxations four weeks after ischemia and progressive reperfusion in canine coronary arteries.
Topics: Acetylcholine; Adenosine Diphosphate; Animals; Arteries; Bradykinin; Coronary Vessels; Dogs; Dose-Re | 1996 |
Effects of organotypic culture on parasympathetic innervation of guinea pig trachealis.
Topics: Analysis of Variance; Animals; Atropine; Electric Stimulation; Enzyme Inhibitors; Esophagus; Guinea | 1996 |
Evidence that potassium channels make a major contribution to SIN-1-evoked relaxation of rat isolated mesenteric artery.
Topics: Animals; Cyclic GMP; Endothelium, Vascular; In Vitro Techniques; Male; Mesenteric Arteries; Molsidom | 1996 |
A possible role for nitric oxide in the regulation of human ureteral smooth muscle tone in vitro.
Topics: Cyclic GMP; Electric Stimulation; Enzyme Inhibitors; Humans; Immunohistochemistry; In Vitro Techniqu | 1996 |
Heterogeneity in the vasorelaxing effect of nicorandil on dog epicardial coronary arteries: comparison with other NO donors.
Topics: Animals; Atrial Natriuretic Factor; Benzopyrans; Coronary Vessels; Cromakalim; Cyclic GMP; Dogs; Fem | 1997 |
The possible role of hydrogen sulfide as an endogenous smooth muscle relaxant in synergy with nitric oxide.
Topics: Animals; Brain; Cystathionine beta-Synthase; Cystathionine gamma-Lyase; Dose-Response Relationship, | 1997 |
Nitric oxide and cyclic nucleotides participate in the relaxation of diclofenac on rat uterine smooth muscle.
Topics: Adenylyl Cyclases; Animals; Cyclic GMP; Cyclooxygenase Inhibitors; Diclofenac; Drug Interactions; En | 1998 |
Mechanisms of relaxations of bovine isolated bronchioles by the nitric oxide donor, GEA 3175.
Topics: Albuterol; Aminoquinolines; Animals; Apamin; Bronchi; Bronchodilator Agents; Cattle; Charybdotoxin; | 1998 |
Evidence that different mechanisms underlie smooth muscle relaxation to nitric oxide and nitric oxide donors in the rabbit isolated carotid artery.
Topics: Acetylcholine; Animals; Apamin; Calcimycin; Carotid Arteries; Cell Membrane; Cyclic GMP; Glyburide; | 1998 |
Interactions between endothelium-derived relaxing factors in the rat hepatic artery: focus on regulation of EDHF.
Topics: Animals; Apamin; Biological Factors; Charybdotoxin; Endothelium, Vascular; Hepatic Artery; Iloprost; | 1998 |
Role of nonselective cation channels as Ca2+ entry pathway in endothelin-1-induced contraction and their suppression by nitric oxide.
Topics: Animals; Aorta; Calcium; Calcium Channel Blockers; Endothelin-1; Imidazoles; In Vitro Techniques; Io | 1998 |
Role of sarcoplasmic reticulum in the myorelaxant activity of nitric oxide donors in guinea pig gastric fundus.
Topics: Acetylcholine; Animals; Calcimycin; Calcium; Enzyme Inhibitors; Gastric Fundus; Guinea Pigs; Indoles | 1998 |
Inhibitory effects of nitric oxide donors on nitric oxide synthesis in rat gastric myenteric plexus.
Topics: Animals; Calcium Channels; Citrulline; Cyclic GMP; Dose-Response Relationship, Drug; Gastric Mucosa; | 1998 |
Protein kinase G expression in the small intestine and functional importance for smooth muscle relaxation.
Topics: Alkaloids; Animals; Carbazoles; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Enzyme Inhibitors; | 1998 |
Acetylcholine-induced relaxation in blood vessels from endothelial nitric oxide synthase knockout mice.
Topics: Acetylcholine; Animals; Aorta; Blood Vessels; Carotid Arteries; Coronary Vessels; Cromakalim; Dose-R | 1999 |
In vitro simultaneous measurements of relaxation and nitric oxide concentration in rat superior mesenteric artery.
Topics: Acetylcholine; Animals; Endothelium, Vascular; Enzyme Inhibitors; In Vitro Techniques; Male; Mesente | 1999 |
2,5-Di-t-butyl-1,4-benzohydroquinone induces endothelium-dependent relaxation of rat thoracic aorta.
Topics: Animals; Aorta, Thoracic; Chelating Agents; Ditiocarb; Dose-Response Relationship, Drug; Endothelium | 1999 |
Cyclic GMP regulates cromakalim-induced relaxation in the rat aortic smooth muscle: role of cyclic GMP in K(ATP)-channels.
Topics: Adenosine Triphosphate; Animals; Aorta, Thoracic; Apamin; Calcium; Charybdotoxin; Cromakalim; Cyclic | 1999 |
Dioclein, a new nitric oxide- and endothelium-dependent vasodilator flavonoid.
Topics: Animals; Aorta, Thoracic; Brazil; Cyclic GMP; Endothelium, Vascular; Flavanones; Flavonoids; In Vitr | 1999 |
Investigation of the interaction between nitric oxide and vasoactive intestinal polypeptide in the guinea-pig gastric fundus.
Topics: Adenine; Adrenergic beta-Agonists; Animals; Atrial Natriuretic Factor; Carbachol; Colforsin; Cyclic | 2000 |
Impaired relaxation of stomach smooth muscle in mice lacking cyclic GMP-dependent protein kinase I.
Topics: Animals; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Electric Stimulation; Female; Fluorescent | 2000 |
Nitric oxide-induced cGMP accumulation in the mouse bladder is not related to smooth muscle relaxation.
Topics: Animals; Arginine; Carbachol; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Electric Sti | 2000 |
Cyclooxygenase-derived products, rather than nitric oxide, are endothelium-derived relaxing factor(s) in the ventral aorta of carp (Cyprinus carpio).
Topics: Acetylcholine; Animals; Aorta; Calcimycin; Carps; Cyclic GMP; Endothelium, Vascular; Enzyme Inhibito | 2000 |
Nitric oxide donor improved the impaired endothelial-dependent relaxation of canine hepatic artery after preservation with UW solution.
Topics: Acetylcholine; Adenosine; Allopurinol; Animals; Dogs; Endothelium, Vascular; Glutathione; Hepatic Ar | 2000 |
Actions of NO donors and endogenous nitrergic transmitter on the longitudinal muscle of rat ileum in vitro: mechanisms involved.
Topics: Animals; Apamin; Atropine; Calcium Channels; Charybdotoxin; Dose-Response Relationship, Drug; Drug I | 2001 |
NO-induced relaxation of labouring and non-labouring human myometrium is not mediated by cyclic GMP.
Topics: Charybdotoxin; Cyclic GMP; Cysteine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Gu | 2001 |
Comparative vasodilation of peroxynitrite and 3-morpholinosydnonimine.
Topics: Adenine; Animals; Benzoates; Cattle; Dose-Response Relationship, Drug; Drug Combinations; Drug Inter | 2001 |
Cellular mechanisms of nitric oxide-induced relaxation of corporeal smooth muscle in the guinea-pig.
Topics: Animals; Calcium; Calcium Channel Blockers; Dose-Response Relationship, Drug; Guinea Pigs; Intracell | 2002 |
Actions of S-nitroso N-acetyl penicillamine and 3-morpholinosydonimine may involve disparate signaling pathways in myometrial smooth muscle.
Topics: Animals; Blotting, Western; Calcium; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP-De | 2001 |
Pharmacological interaction experiments differentiate between glibenclamide-sensitive K+ channels and cyclic GMP as components of vasodilation by nicorandil.
Topics: Animals; Benzopyrans; Cattle; Coronary Vessels; Cromakalim; Cyclic GMP; Drug Interactions; Glyburide | 1992 |
Characterization of inhibitory neurotransmission in the isolated corpus cavernosum from rabbit and man.
Topics: Animals; Arginine; Electric Stimulation; Humans; Male; Molsidomine; Muscle Contraction; Muscle Relax | 1992 |
Total prevention of the development of in vitro tolerance to organic nitrates. Experiments with antioxidants.
Topics: Animals; Antioxidants; Aorta, Thoracic; Drug Tolerance; Female; Guanylate Cyclase; In Vitro Techniqu | 1992 |
Inhibitors of calmodulin impair the constitutive but not the inducible nitric oxide synthase activity in the rat aorta.
Topics: Amino Acid Oxidoreductases; Animals; Aorta; Arginine; Calmodulin; Cyclic GMP; Drug Interactions; End | 1992 |
Inhibition by L-NG-nitro-L-arginine of nonadrenergic-noncholinergic-mediated relaxations of human isolated central and peripheral airway.
Topics: Arginine; Bronchi; Chymotrypsin; Electric Stimulation; Humans; In Vitro Techniques; Molsidomine; Mus | 1992 |
Characterization of endothelium-dependent relaxations resistant to nitro-L-arginine in the porcine coronary artery.
Topics: Animals; Arginine; Bradykinin; Coronary Vessels; Dinoprost; Endothelium, Vascular; In Vitro Techniqu | 1992 |
The impairment of endothelium-dependent relaxations in reversed vein grafts is associated with a reduced production of cyclic guanosine monophosphate.
Topics: Acetylcholine; Animals; Carotid Arteries; Cyclic GMP; Endothelium, Vascular; Hemoglobins; In Vitro T | 1991 |
Nitrate tolerance induced by nicorandil or nitroglycerin is associated with minimal loss of nicorandil vasodilator activity.
Topics: Animals; Arteries; Cattle; Coronary Vessels; Drug Tolerance; In Vitro Techniques; Isosorbide Dinitra | 1990 |
Effects of in vivo SIN1 treatment on nitrovasodilator relaxation and on EDRF-mediated responses in rat aorta.
Topics: Animals; Aorta, Thoracic; Drug Evaluation, Preclinical; Drug Tolerance; Enzyme Activation; Guanylate | 1990 |
Effect of carbenoxolone on the biological activity of nitric oxide: relation to gastroprotection.
Topics: Animals; Aorta; Arginine; Carbenoxolone; Gastric Mucosa; Humans; Iloprost; In Vitro Techniques; Male | 1991 |
Cardioprotection and attenuation of endothelial dysfunction by organic nitric oxide donors in myocardial ischemia-reperfusion.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Animals; Calcimyc | 1992 |
Synergistic actions of nitrovasodilators and isoprenaline on rat aortic smooth muscle.
Topics: Adenylyl Cyclases; Animals; Aorta; Dose-Response Relationship, Drug; Drug Synergism; In Vitro Techni | 1991 |
Effect of the molsidomine metabolite SIN-1 on coronary arteries and peripheral vessels of sheep with special reference to tolerance and endothelium.
Topics: Animals; Blood Vessels; Coronary Vessels; Dose-Response Relationship, Drug; Drug Tolerance; Endothel | 1991 |
Relaxations to SIN-1, nitric oxide, and sodium nitroprusside in canine arteries and veins.
Topics: Analysis of Variance; Animals; Dinoprost; Dogs; Endothelins; Endothelium, Vascular; Femoral Artery; | 1989 |
Effects of SIN-1 on isolated canine basilar arteries.
Topics: Animals; Basilar Artery; Cyclic GMP; Dogs; In Vitro Techniques; Molsidomine; Muscle Relaxation; Nitr | 1989 |
Stimulation of soluble coronary arterial guanylate cyclase by SIN-1.
Topics: Animals; Cations, Divalent; Cattle; Coronary Vessels; Cyclic GMP; Ferricyanides; Guanylate Cyclase; | 1986 |
Mechanism of vasodilation by molsidomine.
Topics: Animals; Cattle; Coronary Vessels; Cyclic GMP; Drug Tolerance; In Vitro Techniques; Molsidomine; Mus | 1985 |
Cyclic GMP as the mediator of molsidomine-induced vasodilatation.
Topics: Animals; Cattle; Coronary Vessels; Cyclic GMP; Dose-Response Relationship, Drug; Drug Synergism; Dru | 1986 |