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linsidomine and Insulin Sensitivity

linsidomine has been researched along with Insulin Sensitivity in 7 studies

linsidomine: RN given refers to parent cpd; structure

Research Excerpts

ExcerptRelevanceReference
"Insulin sensitivity is maximal in the postprandial state, decreasing with a fasting period through a mechanism that is dependent on the integrity of the hepatic parasympathetic nerves/nitric oxide (NO) production and increased hepatic glutathione (GSH) levels."1.38Understanding the in-vivo relevance of S-nitrosothiols in insulin action. ( Fernandes, AB; Guarino, MP; Macedo, MP, 2012)
"Insulin sensitivity was assessed using a transient euglycemic clamp."1.33Co-administration of glutathione and nitric oxide enhances insulin sensitivity in Wistar rats. ( Guarino, MP; Macedo, MP, 2006)
"Insulin sensitivity was restored to 321."1.32Hepatic glutathione and nitric oxide are critical for hepatic insulin-sensitizing substance action. ( Afonso, RA; Guarino, MP; Macedo, MP; Raimundo, N; Raposo, JF, 2003)
"Insulin sensitivity was assessed using a euglycemic clamp [the rapid insulin sensitivity test (RIST)]."1.32Insulin sensitivity is mediated by the activation of the ACh/NO/cGMP pathway in rat liver. ( Correia, NC; Guarino, MP; Lautt, WW; Macedo, MP, 2004)
"Insulin sensitivity was measured using the rapid insulin sensitivity test."1.30Blockade of hepatic nitric oxide synthase causes insulin resistance. ( Lautt, WW; Sadri, P, 1999)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (14.29)18.2507
2000's5 (71.43)29.6817
2010's1 (14.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Zhou, J1
Huang, K1
Fernandes, AB1
Guarino, MP5
Macedo, MP5
Afonso, RA1
Raimundo, N1
Raposo, JF1
Correia, NC2
Lautt, WW2
Sadri, P1
Raposo, J1

Other Studies

7 other studies available for linsidomine and Insulin Sensitivity

ArticleYear
Peroxynitrite mediates muscle insulin resistance in mice via nitration of IRbeta/IRS-1 and Akt.
    Toxicology and applied pharmacology, 2009, Nov-15, Volume: 241, Issue:1

    Topics: Animals; Dietary Fats; Gene Expression Regulation, Enzymologic; Insulin; Insulin Receptor Substrate

2009
Understanding the in-vivo relevance of S-nitrosothiols in insulin action.
    Canadian journal of physiology and pharmacology, 2012, Volume: 90, Issue:7

    Topics: Animals; Blood Glucose; Fasting; Insulin; Insulin Resistance; Male; Molsidomine; Nitric Oxide; Postp

2012
Hepatic glutathione and nitric oxide are critical for hepatic insulin-sensitizing substance action.
    American journal of physiology. Gastrointestinal and liver physiology, 2003, Volume: 284, Issue:4

    Topics: Animals; Buthionine Sulfoximine; Diabetes Mellitus, Type 2; Enzyme Inhibitors; Glutathione; Injectio

2003
Insulin sensitivity is mediated by the activation of the ACh/NO/cGMP pathway in rat liver.
    American journal of physiology. Gastrointestinal and liver physiology, 2004, Volume: 287, Issue:3

    Topics: Acetylcholine; Animals; Cyclic GMP; Enzyme Inhibitors; Guanylate Cyclase; In Vitro Techniques; Injec

2004
Co-administration of glutathione and nitric oxide enhances insulin sensitivity in Wistar rats.
    British journal of pharmacology, 2006, Volume: 147, Issue:8

    Topics: Animals; Dose-Response Relationship, Drug; Drug Administration Routes; Drug Therapy, Combination; Fa

2006
Blockade of hepatic nitric oxide synthase causes insulin resistance.
    The American journal of physiology, 1999, Volume: 277, Issue:1

    Topics: Animals; Denervation; Enzyme Inhibitors; Injections; Injections, Intravenous; Insulin Resistance; Li

1999
Nitric oxide synthase inhibition decreases output of hepatic insulin sensitizing substance (HISS), which is reversed by SIN-1 but not by nitroprusside.
    Proceedings of the Western Pharmacology Society, 2001, Volume: 44

    Topics: Animals; Enzyme Inhibitors; Injections, Intravenous; Insulin; Insulin Resistance; Liver; Male; Molsi

2001
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