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linsidomine and Hypotension

linsidomine has been researched along with Hypotension in 4 studies

linsidomine: RN given refers to parent cpd; structure

Hypotension: Abnormally low BLOOD PRESSURE that can result in inadequate blood flow to the brain and other vital organs. Common symptom is DIZZINESS but greater negative impacts on the body occur when there is prolonged depravation of oxygen and nutrients.

Research Excerpts

ExcerptRelevanceReference
"Amitriptyline intoxication was induced by the continuous infusion of amitriptyline 0."5.31The effect of the nitric oxide synthesis inhibitor L-NAME on amitriptyline-induced hypotension in rats. ( Arkan, F; Aygoren, O; Guven, H; Kalkan, S; Kurt, S; Murat, N; Tuncok, Y, 2002)
"Amitriptyline intoxication was induced by the continuous infusion of amitriptyline 0."1.31The effect of the nitric oxide synthesis inhibitor L-NAME on amitriptyline-induced hypotension in rats. ( Arkan, F; Aygoren, O; Guven, H; Kalkan, S; Kurt, S; Murat, N; Tuncok, Y, 2002)
"We sought to investigate whether linsidomine chlorhydrate (SIN1, the active metabolite of molsidomine and a nitric oxide donor) has a toxic effect when used chronically for the treatment of impotence."1.29Intracavernous injection of linsidomine chlorhydrate in monkeys: lack of toxic effect with long-term use. ( Brock, GB; Lue, TF; Martinez-Piñeiro, L; von Heyden, B, 1996)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (50.00)18.2507
2000's2 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Tuncok, Y1
Kalkan, S1
Murat, N1
Arkan, F1
Guven, H1
Aygoren, O1
Kurt, S1
Takakura, K1
Xiaohong, W1
Takeuchi, K1
Yasuda, Y1
Fukuda, S1
Kovách, AG1
Lohinai, Z1
Marczis, J1
Balla, I1
Dawson, TM1
Snyder, SH1
von Heyden, B1
Brock, GB1
Martinez-Piñeiro, L1
Lue, TF1

Other Studies

4 other studies available for linsidomine and Hypotension

ArticleYear
The effect of the nitric oxide synthesis inhibitor L-NAME on amitriptyline-induced hypotension in rats.
    Journal of toxicology. Clinical toxicology, 2002, Volume: 40, Issue:2

    Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Blood Pressure; Drug Interactions; Enzyme

2002
Deactivation of norepinephrine by peroxynitrite as a new pathogenesis in the hypotension of septic shock.
    Anesthesiology, 2003, Volume: 98, Issue:4

    Topics: Anesthesia; Animals; Aorta, Thoracic; Binding, Competitive; Blood Pressure; Hydrogen-Ion Concentrati

2003
The effect of hemorrhagic hypotension and retransfusion and 7-nitro-indazole on rCBF, NOS catalytic activity, and cortical NO content in the cat.
    Annals of the New York Academy of Sciences, 1994, Nov-17, Volume: 738

    Topics: Acetylcholine; Adenosine Triphosphate; Amino Acid Oxidoreductases; Analgesics; Animals; Arginine; Bl

1994
Intracavernous injection of linsidomine chlorhydrate in monkeys: lack of toxic effect with long-term use.
    European urology, 1996, Volume: 30, Issue:4

    Topics: Animals; Blood Pressure; Hypotension; Macaca fascicularis; Macaca nemestrina; Male; Molsidomine; Pen

1996