linsidomine has been researched along with Cardiac Hypertrophy in 3 studies
linsidomine: RN given refers to parent cpd; structure
Cardiac Hypertrophy: Enlargement of the HEART due to chamber HYPERTROPHY, an increase in wall thickness without an increase in the number of cells (MYOCYTES, CARDIAC). It is the result of increase in myocyte size, mitochondrial and myofibrillar mass, as well as changes in extracellular matrix.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We tested the hypothesis that increasing myocardial cyclic GMP levels would reduce myocardial O2 consumption and that renal hypertension (One Kidney-One Clip, 1K1C)-induced cardiac hypertrophy would change this relationship." | 7.69 | Negative metabolic effects of cyclic GMP are altered in renal hypertension induced cardiac hypertrophy. ( Naim, KL; Rabindranauth, P; Sadoff, JD; Scholz, PM; Tse, J; Weiss, HR, 1997) |
| "We tested the hypothesis that increasing myocardial cyclic GMP would attenuate cyclic AMP induced positive inotropy and O2 consumption, in part, through changes in cyclic AMP and that renal hypertension-induced cardiac hypertrophy (HYP) would alter this relationship." | 3.70 | Cyclic GMP attenuates cyclic AMP-stimulated inotropy and oxygen consumption in control and hypertrophic hearts. ( Leone, RJ; Scholz, PM; Straznicka, M; Weiss, HR, 2000) |
| "We tested the hypothesis that increasing myocardial cyclic GMP levels would reduce myocardial O2 consumption and that renal hypertension (One Kidney-One Clip, 1K1C)-induced cardiac hypertrophy would change this relationship." | 3.69 | Negative metabolic effects of cyclic GMP are altered in renal hypertension induced cardiac hypertrophy. ( Naim, KL; Rabindranauth, P; Sadoff, JD; Scholz, PM; Tse, J; Weiss, HR, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rabindranauth, P | 1 |
| Naim, KL | 1 |
| Scholz, PM | 2 |
| Tse, J | 1 |
| Sadoff, JD | 1 |
| Weiss, HR | 2 |
| Ritchie, RH | 1 |
| Schiebinger, RJ | 1 |
| LaPointe, MC | 1 |
| Marsh, JD | 1 |
| Leone, RJ | 1 |
| Straznicka, M | 1 |
3 other studies available for linsidomine and Cardiac Hypertrophy
| Article | Year |
|---|---|
Negative metabolic effects of cyclic GMP are altered in renal hypertension induced cardiac hypertrophy.
Topics: Animals; Blood Gas Analysis; Cardiomegaly; Coronary Circulation; Cyclic GMP; Enzyme Inhibitors; Guan | 1997 |
Angiotensin II-induced hypertrophy of adult rat cardiomyocytes is blocked by nitric oxide.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Angiotensin II; Animals; Bradyk | 1998 |
Cyclic GMP attenuates cyclic AMP-stimulated inotropy and oxygen consumption in control and hypertrophic hearts.
Topics: Animals; Cardiomegaly; Cardiotonic Agents; Cyclic AMP; Cyclic GMP; Isoproterenol; Molsidomine; Myoca | 2000 |