linsidomine has been researched along with Brain Ischemia in 11 studies
linsidomine: RN given refers to parent cpd; structure
Brain Ischemia: Localized reduction of blood flow to brain tissue due to arterial obstruction or systemic hypoperfusion. This frequently occurs in conjunction with brain hypoxia (HYPOXIA, BRAIN). Prolonged ischemia is associated with BRAIN INFARCTION.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (27.27) | 18.2507 |
| 2000's | 8 (72.73) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Coert, BA | 1 |
| Anderson, RE | 1 |
| Meyer, FB | 1 |
| Ju, C | 2 |
| Oh, YJ | 1 |
| Han, BH | 1 |
| Kim, HS | 1 |
| Kim, HC | 2 |
| Kim, WK | 2 |
| Wen, TC | 2 |
| Rogido, MR | 1 |
| Moore, JE | 1 |
| Genetta, T | 1 |
| Peng, H | 2 |
| Sola, A | 1 |
| Choi, JW | 3 |
| Yoo, BK | 1 |
| Ryu, MK | 2 |
| Choi, MS | 2 |
| Park, GH | 2 |
| Ko, KH | 3 |
| Yoo, oK | 1 |
| Jeon, MJ | 1 |
| Kaundal, RK | 1 |
| Shah, KK | 1 |
| Sharma, SS | 1 |
| Zhang, F | 2 |
| Iadecola, C | 2 |
| White, JG | 1 |
| Tanaka, J | 1 |
| Maeda, N | 1 |
| Matsuda, S | 1 |
| Desaki, J | 1 |
| Sudo, S | 1 |
| Zhang, B | 1 |
| Sakanaka, M | 1 |
| Bastianetto, S | 1 |
| Zheng, WH | 1 |
| Quirion, R | 1 |
| Shin, CY | 1 |
| Jang, ES | 1 |
| Choi, CR | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Statin Therapy To Limit Cognitive Dysfunction After Cardiac Surgery[NCT01186289] | 0 participants (Actual) | Interventional | 2010-10-31 | Withdrawn (stopped due to Principal Investigator decided not to pursue enrollment due to changes in standard of care.) | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
11 other studies available for linsidomine and Brain Ischemia
| Article | Year |
|---|---|
Effects of the nitric oxide donor 3-morpholinosydnonimine (SIN-1) in focal cerebral ischemia dependent on intracellular brain pH.
Topics: Animals; Brain Ischemia; Cerebral Cortex; Cerebral Infarction; Cerebrovascular Circulation; Hydrogen | 2002 |
Intracellular pH-dependent peroxynitrite-evoked synergistic death of glucose-deprived astrocytes.
Topics: Amiloride; Ammonium Chloride; Anaerobiosis; Animals; Astrocytes; Brain Ischemia; Caspases; Cyclospor | 2004 |
Cardiotrophin-1 protects cortical neuronal cells against free radical-induced injuries in vitro.
Topics: Animals; Brain Damage, Chronic; Brain Ischemia; Cells, Cultured; Cerebral Cortex; Cerebral Infarctio | 2005 |
Adenosine and purine nucleosides prevent the disruption of mitochondrial transmembrane potential by peroxynitrite in rat primary astrocytes.
Topics: Adenosine; Animals; Astrocytes; Brain Ischemia; Cell Survival; Cells, Cultured; Dose-Response Relati | 2005 |
Mitogen-activated protein kinases (MAPKs) mediate SIN-1/ glucose deprivation-induced death in rat primary astrocytes.
Topics: Adenosine Triphosphate; Animals; Anthracenes; Astrocytes; Brain Ischemia; Cell Culture Techniques; C | 2005 |
Neuroprotective effects of NU1025, a PARP inhibitor in cerebral ischemia are mediated through reduction in NAD depletion and DNA fragmentation.
Topics: Animals; Apoptosis; Brain; Brain Ischemia; Cell Survival; Disease Models, Animal; DNA Fragmentation; | 2006 |
Reduction of focal cerebral ischemic damage by delayed treatment with nitric oxide donors.
Topics: Animals; Brain; Brain Ischemia; Cerebrovascular Circulation; Electroencephalography; Male; Molsidomi | 1994 |
Nitric oxide donors increase blood flow and reduce brain damage in focal ischemia: evidence that nitric oxide is beneficial in the early stages of cerebral ischemia.
Topics: Animals; Arterial Occlusive Diseases; Brain; Brain Ischemia; Cerebral Arteries; Cerebral Infarction; | 1994 |
Epidermal growth factor protects neuronal cells in vivo and in vitro against transient forebrain ischemia- and free radical-induced injuries.
Topics: Animals; Apoptosis; Avoidance Learning; Brain Ischemia; Cells, Cultured; DNA Fragmentation; Epiderma | 1998 |
The Ginkgo biloba extract (EGb 761) protects and rescues hippocampal cells against nitric oxide-induced toxicity: involvement of its flavonoid constituents and protein kinase C.
Topics: Alkaloids; Alzheimer Disease; Animals; Antioxidants; Azoles; Benzophenanthridines; Brain Ischemia; C | 2000 |
Dehydroepiandrosterone inhibits the death of immunostimulated rat C6 glioma cells deprived of glucose.
Topics: Adjuvants, Immunologic; Animals; Astrocytes; Brain; Brain Ischemia; Cell Death; Cytokines; Dehydroep | 2001 |