linopirdine has been researched along with Memory Disorders in 2 studies
linopirdine: acetylcholine releasing drug
Memory Disorders: Disturbances in registering an impression, in the retention of an acquired impression, or in the recall of an impression. Memory impairments are associated with DEMENTIA; CRANIOCEREBRAL TRAUMA; ENCEPHALITIS; ALCOHOLISM (see also ALCOHOL AMNESTIC DISORDER); SCHIZOPHRENIA; and other conditions.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effects of acute and chronic administration of MKC-231, a new choline uptake enhancer, and two other nootropic agents, linopiridine (Dup 996) and tetrahydroaminoacridine (THA) on working memory deficits and decreased hippocampal acetylcholine (ACh) content were studied in a delayed non-matching to sample task, using a T-maze, in ethylcholine aziridinium ion (AF64A)-treated mice." | 1.29 | MKC-231, a choline uptake enhancer, ameliorates working memory deficits and decreased hippocampal acetylcholine induced by ethylcholine aziridinium ion in mice. ( Abe, E; Itoh, T; Masuda, Y; Murai, S; Odashima, J; Saito, H, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Murai, S | 1 |
| Saito, H | 1 |
| Abe, E | 1 |
| Masuda, Y | 1 |
| Odashima, J | 1 |
| Itoh, T | 1 |
| Börjesson, A | 1 |
| Karlsson, T | 1 |
| Adolfsson, R | 1 |
| Rönnlund, M | 1 |
| Nilsson, L | 1 |
1 trial available for linopirdine and Memory Disorders
| Article | Year |
|---|---|
Linopirdine (DUP 996): cholinergic treatment of older adults using successive and non-successive tests.
Topics: Age Factors; Aged; Analysis of Variance; Cholinergic Agents; Cognition; Cross-Over Studies; Double-B | 1999 |
1 other study available for linopirdine and Memory Disorders
| Article | Year |
|---|---|
MKC-231, a choline uptake enhancer, ameliorates working memory deficits and decreased hippocampal acetylcholine induced by ethylcholine aziridinium ion in mice.
Topics: Acetylcholine; Acetylcholinesterase; Amnesia; Animals; Aziridines; Choline; Choline Deficiency; Data | 1994 |