Page last updated: 2024-10-30

linopirdine and Disease Models, Animal

linopirdine has been researched along with Disease Models, Animal in 9 studies

linopirdine: acetylcholine releasing drug

Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.

Research Excerpts

ExcerptRelevanceReference
"In BFNC, seizures begin shortly after birth, and spontaneously remit in the first few months of life."1.34K+ M-current regulates the transition to seizures in immature and adult hippocampus. ( Johnson, BN; Qiu, C; Tallent, MK, 2007)
"Szt1 mouse seizure thresholds were significantly reduced relative to B6 littermates in the minimal clonic, minimal tonic hindlimb extension, and partial psychomotor seizure models."1.32Mice carrying the szt1 mutation exhibit increased seizure susceptibility and altered sensitivity to compounds acting at the m-channel. ( Frankel, WN; Otto, JF; White, HS; Wilcox, KS; Yang, Y, 2004)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (44.44)29.6817
2010's3 (33.33)24.3611
2020's2 (22.22)2.80

Authors

AuthorsStudies
Solinski, HJ1
Dranchak, P1
Oliphant, E1
Gu, X1
Earnest, TW1
Braisted, J1
Inglese, J1
Hoon, MA1
Abrams, RPM1
Yasgar, A1
Teramoto, T1
Lee, MH1
Dorjsuren, D1
Eastman, RT1
Malik, N1
Zakharov, AV1
Li, W1
Bachani, M1
Brimacombe, K1
Steiner, JP1
Hall, MD1
Balasubramanian, A1
Jadhav, A1
Padmanabhan, R1
Simeonov, A1
Nath, A1
Babu, FS1
Majetschak, M1
Stott, JB1
Barrese, V1
Jepps, TA1
Leighton, EV1
Greenwood, IA1
Sanchez, G1
Rodriguez, MJ1
Pomata, P1
Rela, L1
Murer, MG1
Passmore, GM1
Selyanko, AA1
Mistry, M1
Al-Qatari, M1
Marsh, SJ1
Matthews, EA1
Dickenson, AH1
Brown, TA1
Burbidge, SA1
Main, M1
Brown, DA1
Dost, R1
Rostock, A1
Rundfeldt, C1
Otto, JF1
Yang, Y1
Frankel, WN1
Wilcox, KS1
White, HS1
Qiu, C1
Johnson, BN1
Tallent, MK1

Other Studies

9 other studies available for linopirdine and Disease Models, Animal

ArticleYear
Inhibition of natriuretic peptide receptor 1 reduces itch in mice.
    Science translational medicine, 2019, 07-10, Volume: 11, Issue:500

    Topics: Animals; Behavior, Animal; Cell-Free System; Dermatitis, Contact; Disease Models, Animal; Ganglia, S

2019
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
    Proceedings of the National Academy of Sciences of the United States of America, 2020, 12-08, Volume: 117, Issue:49

    Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Dr

2020
Linopirdine-supplemented resuscitation fluids reduce mortality in a model of ischemia-reperfusion injury induced acute respiratory distress syndrome.
    Physiological research, 2021, 08-31, Volume: 70, Issue:4

    Topics: Animals; Blood Pressure; Disease Models, Animal; Fluid Therapy; Indoles; Infusions, Intravenous; Mal

2021
Contribution of Kv7 channels to natriuretic peptide mediated vasodilation in normal and hypertensive rats.
    Hypertension (Dallas, Tex. : 1979), 2015, Volume: 65, Issue:3

    Topics: Animals; Aorta; Chromans; Cyclic GMP; Disease Models, Animal; Hypertension; Indoles; KCNQ Potassium

2015
Reduction of an afterhyperpolarization current increases excitability in striatal cholinergic interneurons in rat parkinsonism.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2011, Apr-27, Volume: 31, Issue:17

    Topics: Acetylcholine; Action Potentials; Analysis of Variance; Animals; Anthracenes; Apamin; Ascorbic Acid;

2011
KCNQ/M currents in sensory neurons: significance for pain therapy.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2003, Aug-06, Volume: 23, Issue:18

    Topics: Animals; Anthracenes; Anura; Carbamates; Cells, Cultured; CHO Cells; Cricetinae; Disease Models, Ani

2003
The anti-hyperalgesic activity of retigabine is mediated by KCNQ potassium channel activation.
    Naunyn-Schmiedeberg's archives of pharmacology, 2004, Volume: 369, Issue:4

    Topics: Acute Disease; Amines; Analgesics, Opioid; Animals; Carbamates; Cyclohexanecarboxylic Acids; Disease

2004
Mice carrying the szt1 mutation exhibit increased seizure susceptibility and altered sensitivity to compounds acting at the m-channel.
    Epilepsia, 2004, Volume: 45, Issue:9

    Topics: Animals; Anticonvulsants; Carbamates; Disease Models, Animal; Electroshock; Female; Genetic Predispo

2004
K+ M-current regulates the transition to seizures in immature and adult hippocampus.
    Epilepsia, 2007, Volume: 48, Issue:11

    Topics: Action Potentials; Animals; Anticonvulsants; Carbamates; Disease Models, Animal; Epilepsy, Benign Ne

2007