linoleic-acid-hydroperoxide and Neoplasms

Reactive oxygen species (ROS)-induced apoptosis is a widely practiced strategy for cancer therapy. Although photodynamic therapy (PDT) takes advantage of the spatial-temporal control of ROS generation, the meticulous participation of light, photosensitizer, and oxygen greatly hinders the broad application of PDT as a first-line cancer treatment option. An activatable system has been developed that enables tumor-specific singlet oxygen (

Topics: Animals; Apoptosis; Catalysis; Humans; Hydrogen-Ion Concentration; Iron; Linoleic Acids; Lipid Peroxides; Mice; Mice, Nude; Nanoparticles; Neoplasms; Photochemotherapy; Photosensitizing Agents; Reactive Oxygen Species; Singlet Oxygen; Xenograft Model Antitumor Assays