linoleic-acid has been researched along with Rectal-Neoplasms* in 2 studies
1 review(s) available for linoleic-acid and Rectal-Neoplasms
| Article | Year |
|---|---|
Dietary factors in human colorectal cancer.
Colorectal cancer is a significant cause of mortality in Western societies. The progression of the disease from normal colonic epithelium to the acquisition of the malignant phenotype is accompanied by numerous genetic and epigenetic alterations. Compelling experimental and epidemiological evidence indicates that diet and nutrition are key factors in the modulation of colorectal cancer. A salient case in point is the recent observation that a dietary regimen based on a Western-style diet provokes in the rodent colon the appearance of preneoplastic lesions in the absence of any genotoxic insult. This review mainly describes dietary factors that inhibit the development and progression of colorectal cancer. Much is unknown about the precise mechanisms of action of chemically disparate nutrients and how they interfere with the development and progression of this disease. Current knowledge about this important issue is summarized. We believe that continuing scrutiny and precise assessment of the benefits (and potential risks) of nutrients in the treatment and prevention of colorectal cancer will prove significant to controlling this devastating disease. Topics: Animals; Colonic Neoplasms; Diet; Dietary Fiber; Energy Intake; Humans; Linoleic Acid; Nutritional Physiological Phenomena; Rectal Neoplasms; Sphingomyelins | 1999 |
1 other study(ies) available for linoleic-acid and Rectal-Neoplasms
| Article | Year |
|---|---|
Vitamin D, linoleic acid, arachidonic acid and COX-2 in colorectal cancer patients in relation to disease stage, tumour localisation and disease progression.
Evidence shows that vitamin D and cyclooxygenase type 2 (COX-2) might play role in aetiology/progression of cancer. It is suggested that antitumour effect of vitamin D depends on vitamin D-receptor (VDR) expression. Aim of the study was to determine vitamin D and polyunsaturated fatty acids in colorectal cancer patients.. A total of 39 patients with colorectal cancer (mean ± SD age: 65.5 ± 6.8 years) and 25 controls (mean ± SD age: 51.0 ± 6.9 years) were studied. 25-hydroxycholecalciferol-25(OH)D. The mean value of 25(OH)D. The assessment of vitamin D status in patients with colorectal cancer should include measurement of mRNA VDR expression in tumour tissue. Topics: Aged; Arachidonic Acid; Calcifediol; Case-Control Studies; Colon; Colonic Neoplasms; Cyclooxygenase 2; Disease Progression; Female; Humans; Intestinal Mucosa; Linoleic Acid; Male; Middle Aged; Neoplasm Staging; Receptors, Calcitriol; Rectal Neoplasms | 2019 |