linoleic-acid has been researched along with Iridocyclitis* in 1 studies
1 other study(ies) available for linoleic-acid and Iridocyclitis
| Article | Year |
|---|---|
Causal analysis of serum polyunsaturated fatty acids with juvenile idiopathic arthritis and ocular comorbidity.
To investigate the causal effects of plasma Polyunsaturated fatty acids (PUFAs) on the risk of juvenile idiopathic arthritis (JIA) and ocular comorbidity through Mendelian randomization (MR) analysis.. Genetic variants (formerly single nucleotide polymorphisms, SNPs) that are strongly associated with PUFAs levels (P < 5×10. In model 1, genetically predicted n-6 PUFAs linoleic acid (LA) and arachidonic acid (AA) were associated with lower and higher risk of JIA associated iridocyclitis using IVW (OR. Our MR study provides genetic evidence on the possible causality that plasma LA level might protect against JIA associated iridocyclitis, whereas AA was responsible for opposite effect. Topics: Arachidonic Acid; Arthritis, Juvenile; Causality; Comorbidity; Fatty Acids, Unsaturated; Humans; Iridocyclitis; Linoleic Acid; Mendelian Randomization Analysis; Polymorphism, Single Nucleotide | 2023 |