linezolid and Malaria--Falciparum

linezolid has been researched along with Malaria--Falciparum* in 1 studies

Other Studies

1 other study(ies) available for linezolid and Malaria--Falciparum

ArticleYear
Telithromycin and quinupristin-dalfopristin induce delayed death in Plasmodium falciparum.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:2

    Antibacterial agents are used in malaria therapy due to their effect on two prokaryote organelles, the mitochondrion and the apicoplast. We demonstrate here that the ribosome-blocking antibiotics telithromycin and quinupristin-dalfopristin, but not linezolid, inhibit the growth of Plasmodium falciparum. Both drugs induce delayed death in the parasite, suggesting that their effect involves the impairment of apicoplast translation processes.

    Topics: Animals; Humans; Ketolides; Malaria, Falciparum; Parasitic Sensitivity Tests; Plasmodium falciparum; Protein Biosynthesis; Protein Synthesis Inhibitors; Time Factors; Virginiamycin

2008