linezolid and Haemophilus-Infections

linezolid has been researched along with Haemophilus-Infections* in 1 studies

Other Studies

1 other study(ies) available for linezolid and Haemophilus-Infections

Article	Year
New antibacterial tetrahydro-4(2H)-thiopyran and thiomorpholine S-oxide and S,S-dioxide phenyloxazolidinones. Bioorganic & medicinal chemistry letters, 2003, Dec-01, Volume: 13, Issue:23 Combinatorial libraries of N-acylated 5-(S)-aminomethyloxazolidinone derivatives of S-oxide and S,S-dioxide tetrahydro-4(2H)-thiopyranyl and thiomorpholine phenyloxazolidinone series have been synthesized on a solid phase and evaluated for antimicrobial activity. Several novel potent leads have been identified, including orally active oxazolidinones with enhanced activity against respiratory tract infection pathogens Haemophilus influenzae and Moraxella catarrhalis. Topics: Animals; Anti-Bacterial Agents; Biological Availability; Combinatorial Chemistry Techniques; Haemophilus Infections; Haemophilus influenzae; Lipid Metabolism; Male; Microbial Sensitivity Tests; Moraxella catarrhalis; Moraxellaceae Infections; Morpholines; Oxazolidinones; Oxides; Oxygen Compounds; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship	2003

Article

Year

New antibacterial tetrahydro-4(2H)-thiopyran and thiomorpholine S-oxide and S,S-dioxide phenyloxazolidinones.

Bioorganic & medicinal chemistry letters, 2003, Dec-01, Volume: 13, Issue:23

Combinatorial libraries of N-acylated 5-(S)-aminomethyloxazolidinone derivatives of S-oxide and S,S-dioxide tetrahydro-4(2H)-thiopyranyl and thiomorpholine phenyloxazolidinone series have been synthesized on a solid phase and evaluated for antimicrobial activity. Several novel potent leads have been identified, including orally active oxazolidinones with enhanced activity against respiratory tract infection pathogens Haemophilus influenzae and Moraxella catarrhalis.

Topics: Animals; Anti-Bacterial Agents; Biological Availability; Combinatorial Chemistry Techniques; Haemophilus Infections; Haemophilus influenzae; Lipid Metabolism; Male; Microbial Sensitivity Tests; Moraxella catarrhalis; Moraxellaceae Infections; Morpholines; Oxazolidinones; Oxides; Oxygen Compounds; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship

2003