Page last updated: 2024-08-22

limonene and Disease Models, Animal

limonene has been researched along with Disease Models, Animal in 28 studies

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (10.71)29.6817
2010's14 (50.00)24.3611
2020's11 (39.29)2.80

Authors

AuthorsStudies
Chiang, SS; Chu, CY; Lee, KT1
Hamilton, TJ; Leigh, S; Szaszkiewicz, J1
Cho, KS; Choi, B; Koo, BS; Lee, B; Lee, IS; Liu, QF; Shin, C; Shin, M; Song, YJ; Yuan, C; Yun, HS1
Boiangiu, RS; Brinza, I; Cioanca, O; Erdogan Orhan, I; Eren, G; Ertas, H; Gündüz, E; Hancianu, M; Hritcu, L1
Aghazadeh, S; Amini, R; Asle-Rousta, M1
Almeida, RS; Araújo-Filho, HG; Douglas Melo Coutinho, H; Gandhi, SR; Grougnet, R; Guedes da Silva Almeida, JR; Heimfarth, L; Martins, N; Pereira, EWM; Picot, L; Quintans, JSS; Quintans-Júnior, LJ; Santos Passos, FR; Siqueira-Lima, P; Souza Monteiro, B; Viana Dos Santos, MR1
Frey, KM; Kurade, M; Ledent, C; Mustafa, SJ; Narke, D; Patel, M; Ponnoth, DS; Rajalingam, S; Siddiquee, A1
Cha, HJ; Gu, SM; Hong, JT; Min, HK; Seo, S; Song, Y; Yun, J1
Amini-Khoei, H; Bijad, E; Boroujeni, SN; Lorigooini, Z; Rahimi-Madiseh, M; Sayyadi-Shahraki, M1
Feng, T; Li, Q; Lv, W; Qian, B; Xu, L; Yu, H; Zhang, Q; Zhu, T1
Adriana Estrella, GR; Alberto, HL; Azucena, CV; Francisco Javier, LM; María Eva, GT; María Guadalupe, VD; Noé, AV; Sandra, OS1
Albuquerque, TR; Alcantara, IS; Araújo, AAS; Araújo-Filho, HG; Barreto, RSS; Coutinho, HDM; Martins, AOBPB; Menezes, IRA; Menezes, PP; Pereira, EWM; Quintans, JSS; Quintans-Júnior, LJ; Rezende, MM; Silva, BAF1
Fan, G; Pan, SY; Ren, JN; Yang, ZY; Yin, KJ; Zhang, LL1
Bene, MC; Bisson, JF; d'Alessio, PA; Mirshahi, M1
Clausen, PA; Hansen, JS; Larsen, ST; Nielsen, GD; Sørli, JB; Wolkoff, P1
Hiruma-Lima, CA; Kushima, H; Moraes, TM; Pellizzon, CH; Rocha, LR; Rozza, AL1
Croda, J; Formagio, AS; Kassuya, CA; Konkiewitz, EC; Oesterreich, SA; Piccinelli, AC; Santos, JA; Ziff, EB1
Bibi, H; Keinan, E; Reany, O; Waisman, D1
Parhi, R; Patnaik, S; Suresh, P1
da Silva, CC; Desoti, VC; Falzirolli, H; Lazarin-Bidóia, D; Martins, SC; Nakamura, CV; Silva, SO; Ueda-Nakamura, T1
Lindgren, BR; Sinha, AA; Wilson, MJ1
Elcombe, BM; Elcombe, CR; Foster, JR; Warnasuriya, GD1
Morimoto, Y; Shibata, Y1
Bauab, TM; Hiruma-Lima, CA; Kushima, H; Marques, MO; Moraes, Tde M; Pellizzon, CH; Rozza, AL; Tanimoto, A1
Jayachitra, J; Nalini, N; Shenbagam, M; Victor Antony Santiago, J1
Kharya, MD; Raghuvanshi, K; Rajak, H; Sah, AK; Sharma, PC; Singh Pawar, R; Singh Thakur, B; Singh, A; Veerasamy, R1
Abdollahi, M; Golshani, S; Karamkhani, F; Monsef-Esfehani, HR1
Witschi, H1

Other Studies

28 other study(ies) available for limonene and Disease Models, Animal

ArticleYear
Ameliorating Effect on Aβ-Induced Alzheimer's Mice by
    Molecules (Basel, Switzerland), 2021, Sep-21, Volume: 26, Issue:18

    Topics: Acyclic Monoterpenes; Alzheimer Disease; Amyloid beta-Peptides; Animals; Brain; Disease Models, Animal; Humans; Limonene; Litsea; Male; Mice; Mice, Inbred C57BL; Morris Water Maze Test; Neuroprotective Agents; Oils, Volatile; Oxidative Stress; Plant Extracts; Powders; tau Proteins

2021
Robust behavioural effects in response to acute, but not repeated, terpene administration in Zebrafish (Danio rerio).
    Scientific reports, 2021, 09-28, Volume: 11, Issue:1

    Topics: Acyclic Monoterpenes; Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Cannabis; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Humans; Hypnotics and Sedatives; Limonene; Locomotion; Zebrafish

2021
Neuroprotective Effects of Limonene (+) against Aβ42-Induced Neurotoxicity in a Drosophila Model of Alzheimer's Disease.
    Biological & pharmaceutical bulletin, 2020, Mar-01, Volume: 43, Issue:3

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Animals, Genetically Modified; Autophagy; Brain; Disease Models, Animal; Drosophila melanogaster; Limonene; MAP Kinase Signaling System; Neuroglia; Neuroprotective Agents; Peptide Fragments; Phosphorylation; Reactive Oxygen Species; Survival; Terpenes

2020
Cognitive Facilitation and Antioxidant Effects of an Essential Oil Mix on Scopolamine-Induced Amnesia in Rats: Molecular Modeling of In Vitro and In Vivo Approaches.
    Molecules (Basel, Switzerland), 2020, Mar-27, Volume: 25, Issue:7

    Topics: Acetylcholinesterase; Amnesia; Animals; Antioxidants; Behavior Rating Scale; Brain; Butyrylcholinesterase; Cholinesterase Inhibitors; Cognition; Disease Models, Animal; Donepezil; Gas Chromatography-Mass Spectrometry; Inhibitory Concentration 50; Limonene; Male; Memory Disorders; Molecular Docking Simulation; Oils, Volatile; Oxidative Stress; Rats; Rats, Wistar; Scopolamine

2020
Hepatoprotective effect of limonene against chronic immobilization induced liver damage in rats.
    Naunyn-Schmiedeberg's archives of pharmacology, 2020, Volume: 393, Issue:11

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Chronic Disease; Cytokines; Disease Models, Animal; Immobilization; Inflammation Mediators; Limonene; Liver; Liver Diseases; Male; Oxidative Stress; Rats, Wistar

2020
Limonene, a food additive, and its active metabolite perillyl alcohol improve regeneration and attenuate neuropathic pain after peripheral nerve injury: Evidence for IL-1β, TNF-α, GAP, NGF and ERK involvement.
    International immunopharmacology, 2020, Volume: 86

    Topics: Animals; Anti-Inflammatory Agents; Disease Models, Animal; Extracellular Signal-Regulated MAP Kinases; Food Additives; GTPase-Activating Proteins; Humans; Interleukin-1beta; Limonene; Male; Mice; Monoterpenes; Motor Neurons; Nerve Growth Factor; Neuralgia; Peripheral Nerve Injuries; Regeneration; Tumor Necrosis Factor-alpha

2020
Limonene-induced activation of A
    Purinergic signalling, 2020, Volume: 16, Issue:3

    Topics: Animals; Asthma; Disease Models, Animal; Inflammation; Limonene; Lung; Mice; Mice, Transgenic; Ovalbumin; Receptor, Adenosine A2A

2020
D-limonene Inhibits Pentylenetetrazole-Induced Seizure via Adenosine A2A Receptor Modulation on GABAergic Neuronal Activity.
    International journal of molecular sciences, 2020, Dec-04, Volume: 21, Issue:23

    Topics: Animals; Basic Helix-Loop-Helix Transcription Factors; Convulsants; Disease Models, Animal; GABAergic Neurons; Gene Expression Regulation; Glutamate Decarboxylase; Hippocampus; Limonene; Mice; Neuronal Plasticity; Pentylenetetrazole; Phosphorylation; Rats; Receptor, Adenosine A2A; Seizures

2020
Limonene through Attenuation of Neuroinflammation and Nitrite Level Exerts Antidepressant-Like Effect on Mouse Model of Maternal Separation Stress.
    Behavioural neurology, 2021, Volume: 2021

    Topics: Animals; Antidepressive Agents; Behavior, Animal; Depression; Disease Models, Animal; Limonene; Maternal Deprivation; Mice; Nitrites

2021
Stratification of lung adenocarcinoma patients for d-limonene intervention based on the expression signature genes.
    Food & function, 2021, Aug-21, Volume: 12, Issue:16

    Topics: Adenocarcinoma of Lung; Animals; Disease Models, Animal; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Limonene; Lung Neoplasms; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Nude

2021
Limonene from Agastache mexicana essential oil produces antinociceptive effects, gastrointestinal protection and improves experimental ulcerative colitis.
    Journal of ethnopharmacology, 2021, Nov-15, Volume: 280

    Topics: Agastache; Analgesics; Animals; Colitis, Ulcerative; Disease Models, Animal; Dose-Response Relationship, Drug; Gastrointestinal Agents; Limonene; Male; Mice; Mice, Inbred BALB C; Monoterpenes; Oils, Volatile; Pain; Rats; Rats, Wistar; Sulfasalazine

2021
D-limonene exhibits superior antihyperalgesic effects in a β-cyclodextrin-complexed form in chronic musculoskeletal pain reducing Fos protein expression on spinal cord in mice.
    Neuroscience, 2017, 09-01, Volume: 358

    Topics: Analgesics; Animals; beta-Cyclodextrins; Capsaicin; Cyclohexenes; Disease Models, Animal; Drug Combinations; Drug Interactions; GABA Agents; Hyperalgesia; Limonene; Male; Mice; Muscle Strength; Musculoskeletal Pain; Nociception; Pain Measurement; Pain Threshold; Proto-Oncogene Proteins c-fos; Spinal Cord; Statistics, Nonparametric; Terpenes

2017
Antidepressant-like Effect of
    Journal of agricultural and food chemistry, 2019, Dec-18, Volume: 67, Issue:50

    Topics: Animals; Antidepressive Agents; Brain-Derived Neurotrophic Factor; Citrus sinensis; Depression; Disease Models, Animal; Hippocampus; Humans; Hypothalamo-Hypophyseal System; Limonene; Male; Mice; Oils, Volatile

2019
Skin repair properties of d-Limonene and perillyl alcohol in murine models.
    Anti-inflammatory & anti-allergy agents in medicinal chemistry, 2014, Volume: 13, Issue:1

    Topics: Administration, Cutaneous; Angiogenesis Inhibitors; Animals; Cells, Cultured; Citrus sinensis; Cyclohexenes; Cytokines; Dermatitis, Irritant; Disease Models, Animal; Endothelium; Female; Fruit; Gene Expression Regulation; Humans; Inflammation Mediators; Limonene; Mice; Mice, Hairless; Microtubules; Monoterpenes; P-Selectin; Phorbol Esters; Phytotherapy; Skin; Terpenes; Wound Healing

2014
Adjuvant and inflammatory effects in mice after subchronic inhalation of allergen and ozone-initiated limonene reaction products.
    Journal of toxicology and environmental health. Part A, 2013, Volume: 76, Issue:19

    Topics: Administration, Inhalation; Air Pollutants; Allergens; Animals; Asthma; Body Weight; Bronchoalveolar Lavage Fluid; Cyclohexenes; Disease Models, Animal; Female; Immunoglobulin E; Inflammation; Limonene; Lung; Mice; Mice, Inbred BALB C; Ovalbumin; Ozone; Terpenes; Toxicity Tests, Subchronic

2013
Healing actions of essential oils from Citrus aurantium and d-limonene in the gastric mucosa: the roles of VEGF, PCNA, and COX-2 in cell proliferation.
    Journal of medicinal food, 2013, Volume: 16, Issue:12

    Topics: Animals; Cell Proliferation; Citrus; Cyclohexenes; Cyclooxygenase 2; Disease Models, Animal; Gastric Mucosa; Limonene; Male; Oils, Volatile; Plant Oils; Proliferating Cell Nuclear Antigen; Rats; Rats, Wistar; Stomach Ulcer; Terpenes; Vascular Endothelial Growth Factor A

2013
Antihyperalgesic and antidepressive actions of (R)-(+)-limonene, α-phellandrene, and essential oil from Schinus terebinthifolius fruits in a neuropathic pain model.
    Nutritional neuroscience, 2015, Volume: 18, Issue:5

    Topics: Anacardiaceae; Animals; Antidepressive Agents; Cyclohexane Monoterpenes; Cyclohexenes; Disease Models, Animal; Fruit; Hyperalgesia; Limonene; Male; Monoterpenes; Neuralgia; Oils, Volatile; Physical Conditioning, Animal; Plant Oils; Rats; Rats, Wistar; Terpenes

2015
Prophylactic treatment of asthma by an ozone scavenger in a mouse model.
    Bioorganic & medicinal chemistry letters, 2015, Jan-15, Volume: 25, Issue:2

    Topics: Administration, Inhalation; Aldehydes; Animals; Anti-Inflammatory Agents, Non-Steroidal; Asthma; Bronchoalveolar Lavage Fluid; Cyclohexenes; Disease Models, Animal; Inflammation; Limonene; Lung; Mice; Mice, Inbred BALB C; Models, Molecular; Molecular Structure; Ovalbumin; Oxidative Stress; Ozone; Reactive Oxygen Species; Spleen; Structure-Activity Relationship; Terpenes

2015
Application of Response Surface Methodology for Design and Optimization of Reservoir-type Transdermal Patch of Simvastatin.
    Current drug delivery, 2016, Volume: 13, Issue:5

    Topics: Administration, Cutaneous; Animals; Biomarkers; Cyclohexenes; Disease Models, Animal; Drug Compounding; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipidemias; Limonene; Lipids; Male; Middle Aged; Models, Statistical; Permeability; Poloxamer; Rats, Sprague-Dawley; Simvastatin; Skin; Skin Absorption; Technology, Pharmaceutical; Terpenes; Time Factors; Transdermal Patch

2016
1,3,4-Thiadiazole derivatives of R-(+)-limonene benzaldehyde-thiosemicarbazones cause death in Trypanosoma cruzi through oxidative stress.
    Microbes and infection, 2016, Volume: 18, Issue:12

    Topics: Animals; Antiprotozoal Agents; Benzaldehydes; Chagas Disease; Cyclohexenes; Disease Models, Animal; Female; Humans; Limonene; Mice, Inbred BALB C; Molecular Structure; Oxidative Stress; Parasite Load; Parasitemia; Terpenes; Thiadiazoles; Thiosemicarbazones; Treatment Outcome; Trypanosoma cruzi

2016
The effect of dietary supplementation with limonene or myo-inositol on the induction of neoplasia and matrix metalloproteinase and plasminogen activator activities in accessory sex organs of male Lobund-Wistar rats.
    Experimental and molecular pathology, 2008, Volume: 85, Issue:2

    Topics: Alkylating Agents; Animals; Anticarcinogenic Agents; Cyclohexenes; Dietary Supplements; Disease Models, Animal; Genitalia, Male; Incidence; Inositol; Limonene; Male; Matrix Metalloproteinases; Methylnitrosourea; Neoplasms; Plasminogen Activators; Random Allocation; Rats; Rats, Wistar; Terpenes; Time Factors

2008
A Mechanism for the induction of renal tumours in male Fischer 344 rats by short-chain chlorinated paraffins.
    Archives of toxicology, 2010, Volume: 84, Issue:3

    Topics: Alpha-Globulins; Animals; Carcinogens; Cell Proliferation; Chlorobenzenes; Cyclohexenes; Disease Models, Animal; Down-Regulation; Female; Hydrocarbons, Chlorinated; Kidney; Kidney Neoplasms; Limonene; Liver; Male; Peroxisomes; Protein Binding; Rats; Rats, Inbred F344; Terpenes; Transcription, Genetic

2010
Effects of various fragrant ingredients on desmopressin-induced fluid retention in mice.
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2010, Volume: 130, Issue:7

    Topics: Animals; Aromatherapy; Cyclohexenes; Deamino Arginine Vasopressin; Disease Models, Animal; Diuretics; Dose-Response Relationship, Drug; Edema; Furosemide; Guaiacol; Limonene; Male; Mice; Mice, Inbred Strains; Terpenes

2010
Gastroprotective mechanisms of Citrus lemon (Rutaceae) essential oil and its majority compounds limonene and β-pinene: involvement of heat-shock protein-70, vasoactive intestinal peptide, glutathione, sulfhydryl compounds, nitric oxide and prostaglandin E
    Chemico-biological interactions, 2011, Jan-15, Volume: 189, Issue:1-2

    Topics: Animals; Bicyclic Monoterpenes; Bridged Bicyclo Compounds; Citrus; Cyclohexenes; Dinoprostone; Disease Models, Animal; Drug Synergism; Glutathione; Helicobacter Infections; Helicobacter pylori; HSP70 Heat-Shock Proteins; Immunohistochemistry; Limonene; Male; Microbial Sensitivity Tests; Monoterpenes; Nitric Oxide; Plant Oils; Protective Agents; Rats; Rats, Wistar; Stomach Ulcer; Sulfhydryl Compounds; Terpenes; Vasoactive Intestinal Peptide

2011
Dietary d-limonene alleviates insulin resistance and oxidative stress-induced liver injury in high-fat diet and L-NAME-treated rats.
    European journal of nutrition, 2012, Volume: 51, Issue:1

    Topics: Animals; Antioxidants; Cyclohexenes; Diet, High-Fat; Dietary Supplements; Disease Models, Animal; Fatty Liver; Insulin; Insulin Resistance; Insulin Secretion; Limonene; Lipid Metabolism; Lipid Peroxidation; Liver; Male; Metabolic Syndrome; NG-Nitroarginine Methyl Ester; Non-alcoholic Fatty Liver Disease; Oxidative Stress; Pancreas; Random Allocation; Rats; Rats, Wistar; Terpenes

2012
Novel limonene and citral based 2,5-disubstituted-1,3,4-oxadiazoles: a natural product coupled approach to semicarbazones for antiepileptic activity.
    Bioorganic & medicinal chemistry letters, 2013, Feb-01, Volume: 23, Issue:3

    Topics: Acyclic Monoterpenes; Animals; Anticonvulsants; Binding Sites; Cyclohexenes; Disease Models, Animal; gamma-Aminobutyric Acid; Limonene; Monoterpenes; Oxadiazoles; Protein Binding; Rats; Seizures; Semicarbazones; Structure-Activity Relationship; Terpenes

2013
Antinociceptive effects of the essential oil of Dracocephalum kotschyi in the mouse writhing test.
    Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques, 2004, Apr-20, Volume: 7, Issue:1

    Topics: Analgesics; Animals; Cyclohexane Monoterpenes; Cyclohexenes; Disease Models, Animal; Drug Therapy, Combination; Indomethacin; Lamiaceae; Limonene; Male; Mice; Monoterpenes; Pain; Pain Measurement; Plant Oils; Scopolamine; Terpenes

2004
Successful and not so successful chemoprevention of tobacco smoke-induced lung tumors.
    Experimental lung research, 2000, Volume: 26, Issue:8

    Topics: Animals; Anticarcinogenic Agents; Aspirin; Chemoprevention; Cyclohexenes; Dexamethasone; Diet; Disease Models, Animal; Drug Therapy, Combination; Inhalation Exposure; Inositol; Isothiocyanates; Limonene; Lung Neoplasms; Mice; Mice, Inbred A; Organoselenium Compounds; Phytotherapy; Tea; Terpenes; Tobacco Smoke Pollution

2000