limaprost and Cataract

The aortitis syndrome is a chronic inflammatory process that affects the aorta and its primary branches. Patients with aortitis syndrome exhibit various ocular changes. We present a patient in whom cataract was the initial objective finding. The serum concentration of vascular endothelial growth factor, a cytokine that affects neovascularization, and vasopermeability, was elevated before the initiation of prednisolone treatment. Cataract should be considered as a possible characteristic initial finding in patients with aortitis syndrome. Vascular endothelial growth factor may be involved in the progression of aortitis syndrome.

Topics: Adult; Alprostadil; Angiography; Carotid Artery, Common; Cataract; Endothelial Growth Factors; Female; Glucocorticoids; Humans; Lymphokines; Prednisolone; Subclavian Artery; Takayasu Arteritis; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors