lignans has been researched along with Malaria--Falciparum* in 2 studies
2 other study(ies) available for lignans and Malaria--Falciparum
| Article | Year |
|---|---|
Bioactive Neolignans and Other Compounds from Magnolia grandiflora L.: Isolation and Antiplasmodial Activity.
Bioassay-guided fractionation of a methanol extract of Magnolia grandiflora against Plasmodium falciparum yielded two new (1 and 2) and six known (3 - 8) bioactive compounds. The structures of the new compounds were assigned by mass spectrometric and 1D- and 2D-NMR data. Known compounds were identified by comparison of Topics: Antimalarials; Humans; Lignans; Magnolia; Malaria, Falciparum; Plant Extracts; Plasmodium falciparum | 2017 |
Antimalarial and antiplasmodial activities of norneolignans. Syntheses and SAR.
A systematic change of the substituents and side chain of the norneolignan hinokiresinol afforded a 10 fold improvement of the IC(50) value toward inhibition of the growth of Plasmodium falciparum. The more potent compounds controlled the parasitemia in mice infected with Plasmodium berghei. Topics: Animals; Antimalarials; Dose-Response Relationship, Drug; In Vitro Techniques; Lignans; Malaria, Falciparum; Mice; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium berghei; Plasmodium falciparum; Structure-Activity Relationship | 2006 |