lidoflazine has been researched along with Coma in 5 studies
Lidoflazine: Coronary vasodilator with some antiarrhythmic action.
Coma: A profound state of unconsciousness associated with depressed cerebral activity from which the individual cannot be aroused. Coma generally occurs when there is dysfunction or injury involving both cerebral hemispheres or the brain stem RETICULAR FORMATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Five hundred twenty patients with cardiac arrest who remained comatose after the restoration of spontaneous circulation were randomly assigned to receive three doses of lidoflazine, an experimental calcium-entry blocker, or a placebo and were followed for six months." | 9.07 | A randomized clinical study of a calcium-entry blocker (lidoflazine) in the treatment of comatose survivors of cardiac arrest. ( , 1991) |
| "Five hundred twenty patients with cardiac arrest who remained comatose after the restoration of spontaneous circulation were randomly assigned to receive three doses of lidoflazine, an experimental calcium-entry blocker, or a placebo and were followed for six months." | 5.07 | A randomized clinical study of a calcium-entry blocker (lidoflazine) in the treatment of comatose survivors of cardiac arrest. ( , 1991) |
| "To assess survival after cardiac arrest and to determine whether age is an independent determinant of late mortality or poor neurologic outcome." | 2.68 | Old age does not negate good cerebral outcome after cardiopulmonary resuscitation: analyses from the brain resuscitation clinical trials. The Brain Resuscitation Clinical Trial I and II Study Groups. ( Abramson, NS; Rogove, HJ; Safar, P; Sutton-Tyrrell, K, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rogove, HJ | 1 |
| Safar, P | 1 |
| Sutton-Tyrrell, K | 1 |
| Abramson, NS | 1 |
| Engler, RL | 1 |
| Plum, F | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Evaluation of Prognosis Factors of Neurological Evolution in Cardiac Arrest : Prospective Study of Routine Care[NCT02849561] | 82 participants (Actual) | Interventional | 2014-01-31 | Completed | |||
| Vasopressin, Epinephrine, and Corticosteroids for Inhospital Cardiac Arrest: A Multicenter Randomized Controlled Trial[NCT00729794] | Phase 3 | 300 participants (Actual) | Interventional | 2008-09-30 | Completed | ||
| Effect of Stress-dose Steroids on Post-resuscitation Infectious (Septic) Complications After In-hospital Cardiac Arrest. Individual Patient Data-based Re-analysis of Synthesized Prior Randomized Clinical Trial Data[NCT02408939] | 191 participants (Actual) | Observational | 2015-03-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 trials available for lidoflazine and Coma
1 other study available for lidoflazine and Coma
| Article | Year |
|---|---|
Lidoflazine in the treatment of comatose survivors of cardiac arrest.
Topics: Coma; Heart Arrest; Humans; Lidoflazine | 1991 |