lidoflazine has been researched along with Brain Damage, Chronic in 3 studies
Lidoflazine: Coronary vasodilator with some antiarrhythmic action.
Brain Damage, Chronic: A condition characterized by long-standing brain dysfunction or damage, usually of three months duration or longer. Potential etiologies include BRAIN INFARCTION; certain NEURODEGENERATIVE DISORDERS; CRANIOCEREBRAL TRAUMA; ANOXIA, BRAIN; ENCEPHALITIS; certain NEUROTOXICITY SYNDROMES; metabolic disorders (see BRAIN DISEASES, METABOLIC); and other conditions.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Five hundred twenty patients with cardiac arrest who remained comatose after the restoration of spontaneous circulation were randomly assigned to receive three doses of lidoflazine, an experimental calcium-entry blocker, or a placebo and were followed for six months." | 9.07 | A randomized clinical study of a calcium-entry blocker (lidoflazine) in the treatment of comatose survivors of cardiac arrest. ( , 1991) |
| "Five hundred twenty patients with cardiac arrest who remained comatose after the restoration of spontaneous circulation were randomly assigned to receive three doses of lidoflazine, an experimental calcium-entry blocker, or a placebo and were followed for six months." | 5.07 | A randomized clinical study of a calcium-entry blocker (lidoflazine) in the treatment of comatose survivors of cardiac arrest. ( , 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Plum, F | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Vasopressin, Epinephrine, and Corticosteroids for Inhospital Cardiac Arrest: A Multicenter Randomized Controlled Trial[NCT00729794] | Phase 3 | 300 participants (Actual) | Interventional | 2008-09-30 | Completed | ||
| Effect of Stress-dose Steroids on Post-resuscitation Infectious (Septic) Complications After In-hospital Cardiac Arrest. Individual Patient Data-based Re-analysis of Synthesized Prior Randomized Clinical Trial Data[NCT02408939] | 191 participants (Actual) | Observational | 2015-03-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 trials available for lidoflazine and Brain Damage, Chronic
| Article | Year |
|---|---|
A randomized clinical trial of calcium entry blocker administration to comatose survivors of cardiac arrest. Design, methods, and patient characteristics. The Brain Resuscitation Clinical Trial II Study Group.
Topics: Brain Damage, Chronic; Cardiopulmonary Resuscitation; Coma; Double-Blind Method; Heart Arrest; Human | 1991 |
A randomized clinical trial of calcium entry blocker administration to comatose survivors of cardiac arrest. Design, methods, and patient characteristics. The Brain Resuscitation Clinical Trial II Study Group.
Topics: Brain Damage, Chronic; Cardiopulmonary Resuscitation; Coma; Double-Blind Method; Heart Arrest; Human | 1991 |
A randomized clinical trial of calcium entry blocker administration to comatose survivors of cardiac arrest. Design, methods, and patient characteristics. The Brain Resuscitation Clinical Trial II Study Group.
Topics: Brain Damage, Chronic; Cardiopulmonary Resuscitation; Coma; Double-Blind Method; Heart Arrest; Human | 1991 |
A randomized clinical trial of calcium entry blocker administration to comatose survivors of cardiac arrest. Design, methods, and patient characteristics. The Brain Resuscitation Clinical Trial II Study Group.
Topics: Brain Damage, Chronic; Cardiopulmonary Resuscitation; Coma; Double-Blind Method; Heart Arrest; Human | 1991 |
A randomized clinical study of a calcium-entry blocker (lidoflazine) in the treatment of comatose survivors of cardiac arrest.
Topics: Brain Damage, Chronic; Calcium Channel Blockers; Coma; Drug Evaluation; Female; Follow-Up Studies; H | 1991 |
Vulnerability of the brain and heart after cardiac arrest.
Topics: Brain; Brain Damage, Chronic; Calcium Channel Blockers; Coma; Heart; Heart Arrest; Humans; Lidoflazi | 1991 |