lidocaine has been researched along with Wounds, Penetrating in 21 studies
Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.
Wounds, Penetrating: Wounds caused by objects penetrating the skin.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To determine whether application of topical aqueous lidocaine to a laceration attenuates the pain from the subsequent lidocaine injection in children." | 6.18 | Use of topical lidocaine in pediatric laceration repair: a review of topical anesthetics. ( Rosenberg, NM; Simpson, P; Stewart, GM, 1998) |
| "To compare pain on infiltration, need for additional anesthesia, and pain on suturing in patients given plain, warm, and buffered lidocaine preparations before the suturing of traumatic wounds in the emergency department." | 5.08 | Comparison of plain, warmed, and buffered lidocaine for anesthesia of traumatic wounds. ( Brogan, GX; Cassara, G; Giarrusso, E; Hollander, JE; Maranga, MC; Thode, HC, 1995) |
| "Our previous study demonstrated that 1% diphenhydramine is as effective as 1% lidocaine for anesthesia in minor laceration repair, but that it also is more painful to inject." | 5.07 | 1% lidocaine versus 0.5% diphenhydramine for local anesthesia in minor laceration repair. ( Ernst, AA; Mall, G; Marvez-Valls, E; Patterson, J; Weiss, SJ; Xie, X, 1994) |
| "The incidence of wound infection was 2." | 1.28 | Comparison of topical tetracaine, adrenaline, and cocaine anesthesia with lidocaine infiltration for repair of lacerations in children. ( Altieri, MF; Greene, A; Hawk, WH; Hegenbarth, MA; O'Donnell, R; Ochsenschlager, DW, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (19.05) | 18.7374 |
| 1990's | 12 (57.14) | 18.2507 |
| 2000's | 3 (14.29) | 29.6817 |
| 2010's | 2 (9.52) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Saghi, B | 1 |
| Momeni, M | 1 |
| Saeedi, M | 1 |
| Ghane, M | 1 |
| Okur, OM | 1 |
| Şener, A | 1 |
| Kavakli, HŞ | 1 |
| Çelik, GK | 1 |
| Doğan, NÖ | 1 |
| Içme, F | 1 |
| Günaydin, GP | 1 |
| Geary, PM | 1 |
| Vanderweele, RA | 1 |
| Schwartz, SA | 1 |
| Beeson, TJ | 1 |
| Brogan, GX | 1 |
| Giarrusso, E | 1 |
| Hollander, JE | 1 |
| Cassara, G | 1 |
| Maranga, MC | 1 |
| Thode, HC | 1 |
| Ernst, AA | 4 |
| Marvez, E | 1 |
| Nick, TG | 2 |
| Chin, E | 1 |
| Wood, E | 1 |
| Gonzaba, WT | 1 |
| Marvez-Valls, E | 2 |
| Weiss, SJ | 2 |
| Mall, G | 1 |
| Patterson, J | 1 |
| Xie, X | 1 |
| Smith, GA | 2 |
| Strausbaugh, SD | 2 |
| Harbeck-Weber, C | 2 |
| Shields, BJ | 2 |
| Powers, JD | 2 |
| Hackenberg, D | 1 |
| Ochsenreither, JM | 1 |
| Stewart, GM | 1 |
| Simpson, P | 1 |
| Rosenberg, NM | 1 |
| Zempsky, WT | 1 |
| Burnett, JW | 1 |
| Zook, EG | 1 |
| Hegenbarth, MA | 1 |
| Altieri, MF | 1 |
| Hawk, WH | 1 |
| Greene, A | 1 |
| Ochsenschlager, DW | 1 |
| O'Donnell, R | 1 |
| Martin, JR | 1 |
| Doezema, D | 1 |
| Tandberg, D | 1 |
| Umland, E | 1 |
| Crabbe, LH | 1 |
| Winsemius, DK | 1 |
| Bragdon, R | 1 |
| Link, R | 1 |
| Fitzgerald, M | 1 |
| Millard, C | 1 |
| McIntosh, N | 1 |
| Zato, M | 1 |
| Zaragoza, P | 1 |
| Lincoff, H | 1 |
| Kreissig, I | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Traditional Dorsal Digital Block vs Volar Subcutaneous Digital Block[NCT05280704] | 150 participants (Anticipated) | Interventional | 2023-12-31 | Not yet recruiting | |||
| Saline Injection - Assisted Anesthesia in Eyelid Surgery[NCT01239498] | Phase 4 | 60 participants (Anticipated) | Interventional | 2010-11-30 | Recruiting | ||
| The Efficacy of the Eutectic Mixture of Local Anesthetics (EMLA) Cream Versus the Synera Patch for Pain Reduction During Venipuncture in Children[NCT00530803] | Phase 2 | 100 participants (Actual) | Interventional | 2007-06-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
The NRS (Numerical Rating Scale) is a 6-point rating scale where 0= no pain and 5 = worst pain. Blinded observers reported their own subjective evaluation of the level of pain experienced by the participants at tourniquet placement. Total number of participants subjectively evaluated as experiencing each pain level is reported. (NCT00530803)
Timeframe: before venipuncture
| Intervention | Participants (Count of Participants) | |||||
|---|---|---|---|---|---|---|
| Participants evaluated at NRS = 0 (No pain) | Participants evaluated at NRS = 1 | Participants evaluated at NRS = 2 | Participants evaluated at NRS = 3 | Participants evaluated at NRS = 4 | Participants evaluated at NRS = 5 | |
| EMLA Cream | 41 | 6 | 2 | 1 | 0 | 0 |
| Synera Patch | 37 | 6 | 5 | 1 | 1 | 0 |
The NRS (Numerical Rating Scale) is a 6-point rating scale where 0= no pain and 5 = worst pain. Blinded observers reported their own subjective evaluation of the level of pain participants were experiencing 5 minutes after the venipuncture was completed. Total number of participants subjectively evaluated as experiencing each pain level is reported. (NCT00530803)
Timeframe: 5 minutes post venipuncture
| Intervention | Participants (Count of Participants) | |||||
|---|---|---|---|---|---|---|
| Participants evaluated at NRS = 0 (No pain) | Participants evaluated at NRS = 1 | Participants evaluated at NRS = 2 | Participants evaluated at NRS = 3 | Participants evaluated at NRS = 4 | Participants evaluated at NRS = 5 | |
| EMLA Cream | 45 | 3 | 1 | 1 | 0 | 0 |
| Synera Patch | 45 | 4 | 1 | 0 | 0 | 0 |
The NRS (Numerical Rating Scale) is a 6-point rating scale where 0= no pain and 5 = worst pain. Blinded observers reported their own subjective evaluation of the level of pain experienced by the participants at needle insertion. Total number of participants subjectively evaluated as experiencing each pain level is reported. (NCT00530803)
Timeframe: during needle insertion
| Intervention | Participants (Count of Participants) | |||||
|---|---|---|---|---|---|---|
| Participants evaluated at NRS = 0 (No pain) | Participants evaluated at NRS = 1 | Participants evaluated at NRS = 2 | Participants evaluated at NRS = 3 | Participants evaluated at NRS = 4 | Participants evaluated at NRS = 5 | |
| EMLA Cream | 32 | 14 | 2 | 2 | 0 | 0 |
| Synera Patch | 25 | 12 | 9 | 2 | 2 | 0 |
The Numerical Rating Scale (NRS) is a 6-point rating scale where 0= no pain and 5 = worst pain. Parents reported their own subjective evaluation of participants pain level. Each participant had only one parental assessment. Total number of parental assessment for each pain level on the 6-point NRS is reported as total number of participants experiencing that pain level. (NCT00530803)
Timeframe: immediately after venipuncture is completed
| Intervention | Participants (Count of Participants) | |||||
|---|---|---|---|---|---|---|
| number of participants with NRS=0 (no pain) | number of participants with NRS=1 | number of participants with NRS=2 | number of participants with NRS=3 | number of participants with NRS=4 | number of participants with NRS=5 | |
| EMLA Cream | 42 | 6 | 1 | 1 | 0 | 0 |
| Synera Patch | 41 | 5 | 1 | 2 | 0 | 1 |
"Participants were asked to report their level of pain using a 6-point Wong-Baker FACES Pain Rating Scale ranging from 0, no pain, to 5, the most pain you can have. The Wong-Baker FACES Pain Rating Scale is a validated tool for measuring pain in patients as young as 3 years old. A FACES pain score less than or equal to 2 is considered no pain to mild pain, and is clinically acceptable. Studies have shown average FACES pain scores for children receiving vascular access with placebo to be 2.2 to 3.5." (NCT00530803)
Timeframe: immediately after completion of venipuncture
| Intervention | Participants (Count of Participants) | |||||
|---|---|---|---|---|---|---|
| Participants with FACES Score = 0 (No pain) | Participants with FACES Score = 1 | Participants with FACES Score = 2 | Participants with FACES Score = 3 | Participants with FACES Score = 4 | Participants with FACES Score = 5 | |
| EMLA Cream | 42 | 6 | 2 | 0 | 0 | 0 |
| Synera Patch | 38 | 8 | 3 | 1 | 0 | 0 |
1 review available for lidocaine and Wounds, Penetrating
| Article | Year |
|---|---|
Use of topical lidocaine in pediatric laceration repair: a review of topical anesthetics.
Topics: Adolescent; Adult; Anesthetics, Local; Child; Child, Preschool; Double-Blind Method; Emergency Servi | 1998 |
11 trials available for lidocaine and Wounds, Penetrating
| Article | Year |
|---|---|
Efficacy of the jet injector in local anaesthesia for small wound sutures: a randomised clinical trial compared with the needle infiltration technique.
Topics: Adult; Anesthesia, Local; Anesthetics, Local; Double-Blind Method; Facial Injuries; Female; Humans; | 2015 |
Two injection digital block versus single subcutaneous palmar injection block for finger lacerations.
Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Local; Drug Administration Schedule; Emergency Service, | 2017 |
Comparison of plain, warmed, and buffered lidocaine for anesthesia of traumatic wounds.
Topics: Adolescent; Adult; Anesthesia, Local; Buffers; Hot Temperature; Humans; Lidocaine; Pain; Pain Measur | 1995 |
Lidocaine adrenaline tetracaine gel versus tetracaine adrenaline cocaine gel for topical anesthesia in linear scalp and facial lacerations in children aged 5 to 17 years.
Topics: Adolescent; Anesthesia, Local; Anesthetics, Local; Child; Child, Preschool; Cocaine; Double-Blind Me | 1995 |
LAT (lidocaine-adrenaline-tetracaine) versus TAC (tetracaine-adrenaline-cocaine) for topical anesthesia in face and scalp lacerations.
Topics: Adult; Anesthetics, Local; Cocaine; Double-Blind Method; Drug Combinations; Drug Costs; Epinephrine; | 1995 |
1% lidocaine versus 0.5% diphenhydramine for local anesthesia in minor laceration repair.
Topics: Adult; Anesthesia, Local; Diphenhydramine; Double-Blind Method; Emergency Service, Hospital; Female; | 1994 |
Comparison of topical anesthetics without cocaine to tetracaine-adrenaline-cocaine and lidocaine infiltration during repair of lacerations: bupivacaine-norepinephrine is an effective new topical anesthetic agent.
Topics: Administration, Cutaneous; Adolescent; Anesthetics, Local; Bupivacaine; Child; Child, Preschool; Coc | 1996 |
Comparison of topical anesthetics with lidocaine infiltration during laceration repair in children.
Topics: Adolescent; Analysis of Variance; Anesthetics, Combined; Anesthetics, Local; Chi-Square Distribution | 1997 |
Use of topical lidocaine in pediatric laceration repair: a review of topical anesthetics.
Topics: Adolescent; Adult; Anesthetics, Local; Child; Child, Preschool; Double-Blind Method; Emergency Servi | 1998 |
Comparison of tetracaine, adrenaline, and cocaine with cocaine alone for topical anesthesia.
Topics: Administration, Topical; Adolescent; Adult; Anesthetics, Local; Child; Child, Preschool; Cocaine; Do | 1990 |
Cutaneous hypersensitivity following peripheral tissue damage in newborn infants and its reversal with topical anaesthesia.
Topics: Anesthetics, Local; Ankle Injuries; Blood Specimen Collection; Double-Blind Method; Drug Combination | 1989 |
10 other studies available for lidocaine and Wounds, Penetrating
| Article | Year |
|---|---|
Removal of foreign bodies using hydrostatic pressure.
Topics: Adult; Anesthetics, Local; Female; Foot; Foot Injuries; Foreign Bodies; Glass; Humans; Hydrostatic P | 2005 |
Effect of blood contamination on retention characteristics of MTA when mixed with different liquids.
Topics: Aluminum Compounds; Analysis of Variance; Anesthetics, Local; Blood; Calcium Compounds; Dental Bondi | 2006 |
Better topical anesthetic.
Topics: Administration, Topical; Adult; Anesthetics, Local; Child; Drug Combinations; Epinephrine; Facial In | 1996 |
Use of topical lidocaine in pediatric laceration repair.
Topics: Anesthetics, Local; Child; Ethics, Medical; Humans; Lidocaine; Pain; Research Design; United States; | 1999 |
Bolus ejection: a method for removing sea urchin spines.
Topics: Anesthetics, Local; Animals; Fingers; Foreign Bodies; Lidocaine; Sea Urchins; Wounds, Penetrating | 2002 |
The care of facial lacerations.
Topics: Anesthesia, Local; Bandages; Debridement; Facial Injuries; First Aid; Humans; Lidocaine; Methods; Pr | 1978 |
Comparison of topical tetracaine, adrenaline, and cocaine anesthesia with lidocaine infiltration for repair of lacerations in children.
Topics: Administration, Topical; Adolescent; Anesthetics, Local; Child; Child, Preschool; Cocaine; Drug Comb | 1990 |
The effect of local anesthetics on bacterial proliferation: TAC versus lidocaine.
Topics: Administration, Topical; Anesthetics, Local; Animals; Bacteria; Cocaine; Drug Combinations; Epinephr | 1990 |
[Use of an embolectomy probe to repair a sectioned lacrimal duct].
Topics: Anesthesia, Local; Catheterization; Humans; Lacrimal Apparatus; Lidocaine; Methods; Wounds, Penetrat | 1986 |
[Local anesthesia with accidental perforation of the eye--an acute emergency?].
Topics: Adult; Anesthetics, Local; Animals; Cats; Electroretinography; Emergencies; Epinephrine; Eye; Eye In | 1986 |