lidocaine has been researched along with Ventricular Fibrillation in 528 studies
Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.
Ventricular Fibrillation: A potentially lethal cardiac arrhythmia that is characterized by uncoordinated extremely rapid firing of electrical impulses (400-600/min) in HEART VENTRICLES. Such asynchronous ventricular quivering or fibrillation prevents any effective cardiac output and results in unconsciousness (SYNCOPE). It is one of the major electrocardiographic patterns seen with CARDIAC ARREST.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effects of prophylactic lidocaine hydrochloride on early ventricular fibrillation and death in patients with suspected acute myocardial infarction were investigated in an overview of 14 randomized trials." | 10.16 | Effects of prophylactic lidocaine in suspected acute myocardial infarction. An overview of results from the randomized, controlled trials. ( Collins, R; Koster, RW; MacMahon, S; Peto, R; Yusuf, S, 1988) |
| "In this randomized, double-blind trial, we compared parenteral amiodarone, lidocaine, and saline placebo, along with standard care, in adults who had nontraumatic out-of-hospital cardiac arrest, shock-refractory ventricular fibrillation or pulseless ventricular tachycardia after at least one shock, and vascular access." | 9.22 | Amiodarone, Lidocaine, or Placebo in Out-of-Hospital Cardiac Arrest. ( Aufderheide, TP; Brienza, AM; Brown, SP; Callaway, CW; Christenson, J; Colella, MR; Daya, M; Desvigne-Nickens, P; Dorian, P; Dunford, JV; Egan, D; Gray, PC; Gray, R; Idris, AH; Kudenchuk, PJ; Leroux, B; Morrison, LJ; Nichol, G; Ornato, JP; Rea, T; Seals, N; Stiell, IG; Straight, R; Vaillancourt, C; Vilke, GM; Weisfeldt, ML; Wittwer, L, 2016) |
| "5 mg/kg, amiodarone 300 mg, or placebo before aortic crossclamp removal The primary outcomes were the incidence of ventricular fibrillation and the number of shocks required to terminate ventricular fibrillation." | 9.16 | Amiodarone versus lidocaine and placebo for the prevention of ventricular fibrillation after aortic crossclamping: a randomized, double-blind, placebo-controlled trial. ( Abel, MD; Barbara, DW; Li, Z; Mauermann, WJ; Meade, LA; Pulido, JN; Schaff, HV; White, RD, 2012) |
| "The frequency of occurrence of ventricular fibrillation was significantly higher in both the amiodarone (48%) and the control group (45%) as compared with the lidocaine group (20%) with no statistically significant difference between the amiodarone and the control groups." | 9.14 | Prophylactic amiodarone versus lidocaine for prevention of reperfusion ventricular fibrillation after release of aortic cross-clamp. ( Ayoub, CM; Azar, M; Bou-Khalil, P; El-Khatib, MF; Haddadin, AS; Harfouch, D; Nasr, VG; Sfeir, PM, 2009) |
| "As compared with lidocaine, amiodarone leads to substantially higher rates of survival to hospital admission in patients with shock-resistant out-of-hospital ventricular fibrillation." | 9.10 | Amiodarone as compared with lidocaine for shock-resistant ventricular fibrillation. ( Barr, A; Cass, D; Cooper, R; Dorian, P; Gelaznikas, R; Schwartz, B, 2002) |
| "Early meta-analyses suggested that prophylactic lidocaine use reduces ventricular fibrillation but increases mortality rates after acute myocardial infarction." | 9.09 | Prophylactic lidocaine use in acute myocardial infarction: incidence and outcomes from two international trials. The GUSTO-I and GUSTO-IIb Investigators. ( Alexander, JH; Aylward, PE; Califf, RM; Granger, CB; Sadowski, Z; Thompson, TD; Topol, EJ; White, HD, 1999) |
| "To determine the efficacy of a bolus of lidocaine administered by way of the pump before releasing the aortic cross-clamp (ACC) in preventing the occurrence of reperfusion ventricular fibrillation." | 9.09 | Lidocaine for prevention of reperfusion ventricular fibrillation after release of aortic cross-clamping. ( Baraka, A; Dabbous, A; Kawkabani, N; Nawfal, M, 2000) |
| "New congestive heart failure developed during the randomized phase in 9% of patients receiving lidocaine and in 2% of patients receiving placebo (p = 0." | 9.08 | Lidocaine prophylaxis for fatal ventricular arrhythmias after acute myocardial infarction. ( Chow, M; Fisher, J; Kluger, J; O'Rangers, E; Pharand, C; Ujhelyi, M, 1995) |
| "The efficacy of lidocaine to prevent ventricular fibrillation during the prehospital phase of suspected acute myocardial infarction was assessed 3 hours after administration in a randomized controlled trial." | 9.07 | Lidocaine to prevent ventricular fibrillation in the prehospital phase of suspected acute myocardial infarction: the North-Norwegian Lidocaine Intervention Trial. ( Berntsen, RF; Rasmussen, K, 1992) |
| "To compare the effects of Lidocaine (LID) alone or with Magnesium Sulfate (M) on life-threatening ventricular arrhythmias which followed cardioverted prolonged ventricular fibrillation (VF) during an acute myocardial infarction (AMI), we studied 34 (24." | 9.07 | Life-threatening arrhythmias after intravenous lidocaine alone or with magnesium in myocardial infarction complicated by ventricular fibrillation. ( Bertanelli, F; Fabiano, P; Leone, A; Mori, L, 1991) |
| "The authors compared bretylium and lidocaine for reducing the incidence and persistence of ventricular fibrillation following aortic cross-clamp release performed during coronary artery bypass surgery." | 9.06 | Comparison of bretylium and lidocaine in the prevention of ventricular fibrillation after aortic cross-clamp release in coronary artery bypass surgery. ( Briggs, R; Goglin, W; Grishkin, B; Helsel, R; Kirlangitis, J; Knight, R; Middaugh, R, 1990) |
| "One hundred ninety-nine patients with out-of-hospital cardiac arrest persisted in ventricular fibrillation after the first defibrillation attempt and were then randomly assigned to receive either epinephrine or lidocaine before the next two shocks." | 9.06 | Effect of epinephrine and lidocaine therapy on outcome after cardiac arrest due to ventricular fibrillation. ( Cobb, LA; Copass, MK; Fahrenbruch, CE; Hallstrom, AP; Johnson, DD; Weaver, WD, 1990) |
| "The prophylactic use of lidocaine in the patient with cardiac chest pain has been reported to reduce the incidence of sudden death from ventricular dysrhythmias in the hospital setting, but few studies have been done in the early prehospital phase." | 9.06 | Prophylactic lidocaine in the prehospital patient with chest pain of suspected cardiac origin. ( Aprahamian, C; Darin, J; Hargarten, KM; Mateer, JR; Stueven, HA; Thompson, BM, 1986) |
| "A prospective, randomized study using either bretylium tosylate (BT) or lidocaine (L) as the first-line antiarrhythmic for patients in refractory ventricular fibrillation was conducted using the Milwaukee County Paramedic System." | 9.05 | A randomized comparison study of bretylium tosylate and lidocaine in resuscitation of patients from out-of-hospital ventricular fibrillation in a paramedic system. ( Darin, JC; Milbrath, MH; Olson, DW; Thompson, BM, 1984) |
| "Within six hours of suspected acute myocardial infarction, 791 patients entered a randomised double blind study of combined intravenous and oral tocainide for the prophylaxis of primary ventricular fibrillation." | 9.05 | Prophylaxis of primary ventricular fibrillation with tocainide in acute myocardial infarction. ( Campbell, RW; Elton, RA; Goodfellow, RM; Hutton, I; Taylor, E, 1983) |
| "Bretylium tosylate was compared with lidocaine hydrochloride as initial drug therapy in 146 victims of out of hospital ventricular fibrillation in a randomized blinded trial." | 9.05 | Comparison of bretylium tosylate and lidocaine in management of out of hospital ventricular fibrillation: a randomized clinical trial. ( Chinn, TL; Cobb, LA; Copass, MK; Haynes, RE, 1981) |
| "To study the efficacy of prophylactic lidocaine treatment on the genesis of ventricular tachyarrhythmias following recanalization of an occluded coronary artery, 49 patients with an acute myocardial infarction were studied." | 9.05 | [Ineffective use of lidocaine in preventing reperfusion arrhythmias in patients with acute myocardial infarct]. ( Jannasch, B; Kuck, KH; Mathey, DG; Schlüter, M; Schofer, J, 1985) |
| "Four hundred two patients with suspected myocardial infarction seen within 6 hours of the onset of symptoms entered a double-blind randomized trial of lidocaine vs placebo." | 9.05 | Prophylactic lidocaine in the early phase of suspected myocardial infarction. ( Adgey, AA; Campbell, NP; Dunn, HM; Kinney, CD; MacKenzie, G; McComb, JM; Shanks, RG, 1985) |
| "In a randomized controlled study examining the value of an intramuscular injection of lidocaine in the prehospitalization phase of suspected acute myocardial infarction, paramedics used an automatic injector to administer 400 mg of the drug into the patient's deltoid muscle before transport to the hospital." | 9.05 | Intramuscular lidocaine for prevention of lethal arrhythmias in the prehospitalization phase of acute myocardial infarction. ( Dunning, AJ; Koster, RW, 1985) |
| "The effectiveness of intramuscular lidocaine in preventing in-hospital primary ventricular fibrillation within 1 hour after injection of the drug in patients with acute myocardial infarction was assessed in a double-blind randomized study performed in 300 such patients admitted within 6 hours of myocardial infarction." | 9.04 | Efficacy of lidocaine in preventing primary ventricular fibrillation within 1 hour after a 300 mg intramuscular injection. A double-blind, randomized study of 300 hospitalized patients with acute myocardial infarction. ( Durrer, D; Janse, MJ; Lie, KI; Liem, KL; Louridtz, WJ; Willebrands, AF, 1978) |
| "In a double blind study performed in cooperation with 69 emergency doctors and general practitioners in the catchment areas of the university and of the city hospital in Lübeck the action of intramuscular lidocaine on mortality and on the incidence of arrhythmias was investigated in patients with acute myocardial infarction aged less than 70 years." | 9.04 | [Lidocaine prophylaxis in the pre-hospital phase of acute myocardial infarction (author's transl)]. ( Diederich, KW; Djonlagić, H; Fassl, H; Floor-Wieringa, A; Oltmanns, D, 1979) |
| "To determine the clinical effectiveness and safety of prophylactic lidocaine in preventing death among people with myocardial infarction." | 8.91 | Prophylactic lidocaine for myocardial infarction. ( Anand, V; Bangdiwala, S; Martí-Carvajal, AJ; Simancas-Racines, D, 2015) |
| "The prophylactic administration of lidocaine for the prevention of primary ventricular fibrillation (VF) following suspected acute myocardial infarction (MI) is controversial." | 8.78 | Lidocaine prophylaxis in acute myocardial infarction. ( Tisdale, JE, 1991) |
| "There appears to be a theoretical basis for the use of lidocaine in treating ventricular arrhythmias secondary to acute ischemia largely based on voltage- and pH-dependent binding and inactivation of sodium channels by lidocaine under ischemic conditions." | 8.78 | Reconsiderations of the routine and preferential use of lidocaine in the emergent treatment of ventricular arrhythmias. ( Resh, W; Wesley, RC; Zimmerman, D, 1991) |
| "In acute myocardial infarction, lidocaine is considered the drug of choice for the treatment of malignant ventricular arrhythmias." | 8.78 | Lidocaine in the early phase of acute myocardial infarction: the controversy over prophylactic or selective use. ( Just, H; Kasper, W; Zehender, M, 1990) |
| "To describe arrhythmias associated with administration of lidocaine in dogs treated for supraventricular tachyarrhythmias." | 8.12 | Rhythm disturbances associated with lidocaine administration in four dogs with supraventricular tachyarrhythmias. ( Connolly, DJ; Luis Fuentes, V; Porteiro Vázquez, DM; Seo, J; Spalla, I; Tinson, E, 2022) |
| "Clinical trials for patients with shock-refractory out-of-hospital cardiac arrest (OHCA), including the Amiodarone, Lidocaine or Placebo (ALPS) trial, have been unable to demonstrate definitive benefit after treatment with antiarrhythmic drugs." | 8.12 | Bayesian analysis of amiodarone or lidocaine versus placebo for out-of-hospital cardiac arrest. ( Christenson, J; Davis, D; Daya, MR; Dorian, P; Grunau, B; Kudenchuk, P; Lane, DJ; Lupton, J; Okubo, M; Rea, T; Scheuermeyer, F; Vaillancourt, C; Wang, HE; Yannopoulos, D, 2022) |
| " We included adult patients with shockable rhythms, such as ventricular fibrillation and pulseless ventricular tachycardia, who were administered either lidocaine or amiodarone." | 8.12 | Comparison of the effects of lidocaine and amiodarone for out-of-hospital cardiac arrest patients with shockable rhythms: a retrospective observational study from a multicenter registry. ( Amagasa, S; Fukushima, F; Kashiura, M; Kishihara, Y; Moriya, T; Yasuda, H, 2022) |
| "International guidelines recommend amiodarone for out-of-hospital cardiac arrest (OHCA) in refractory ventricular fibrillation (VF)." | 8.02 | Time to amiodarone administration and survival outcomes in refractory ventricular fibrillation. ( Bosley, E; Doan, TN; Rashford, S; Schultz, BV; Wilson, D; Wissa, J, 2021) |
| "Active hydraulic ventricular attaching support system (ASD) placed around the heart is not only a novel, nontransplant surgical device used for epicardial administration of drugs like lidocaine, but also a promising treatment option for ventricular fibrillation (VF) and arrhythmias." | 7.91 | A novel approach to devise the therapy for ventricular fibrillation by epicardial delivery of lidocaine using active hydraulic ventricular attaching support system: An experimental study in rats. ( Chen, D; Ihsan, AU; Khan, FU; Li, C; Li, X; Liao, X; Mikrani, R; Sembatya, KR; Wang, Z; Yasmeen, S; Yu, F; Zhou, X, 2019) |
| "The latest resuscitation guidelines recommend the use of amiodarone in adult patients with out-of-hospital cardiac arrest (OHCA) and refractory ventricular fibrillation (VF) to improve the rates of return of spontaneous circulation." | 7.83 | Amiodarone Compared with Lidocaine for Out-Of-Hospital Cardiac Arrest with Refractory Ventricular Fibrillation on Hospital Arrival: a Nationwide Database Study. ( Fushimi, K; Ishinokami, S; Kaneko, J; Kuno, M; Matsui, H; Tagami, T; Tanaka, C; Unemoto, K; Yasunaga, H, 2016) |
| "To determine the association between amiodarone and lidocaine and outcomes in children with cardiac arrest with pulseless ventricular tachycardia (pVT) and ventricular fibrillation (VF)." | 7.80 | Outcomes associated with amiodarone and lidocaine in the treatment of in-hospital pediatric cardiac arrest with pulseless ventricular tachycardia or ventricular fibrillation. ( Berg, MD; Berg, RA; Donoghue, AJ; Hammond, R; Hoyme, DB; Samson, RA; Valdes, SO, 2014) |
| "To compare the early postarrest inflammatory cytokine response between animals administered amiodarone (AMIO) and lidocaine (LIDO) intra-arrest during resuscitation from ventricular fibrillation (VF)." | 7.79 | Administration of amiodarone during resuscitation is associated with higher tumor necrosis factor-α levels in the early postarrest period in the swine model of ischemic ventricular fibrillation. ( Niemann, JT; Rosborough, JP; Shah, AP; Thomas, JL; Youngquist, ST, 2013) |
| "Antiarrhythmic drugs like lidocaine are usually given to promote return of spontaneous circulation (ROSC) during ongoing out-of-hospital cardiac arrest (OHCA) from ventricular fibrillation/tachycardia (VF/VT)." | 7.79 | Prophylactic lidocaine for post resuscitation care of patients with out-of-hospital ventricular fibrillation cardiac arrest. ( Eisenberg, M; Fahrenbruch, C; Kudenchuk, PJ; Newell, C; Rea, T; White, L, 2013) |
| " The sheep were prophylactically treated with amiodarone plus lidocaine before ligation of the four to six coronary artery branches supplying the apex of the heart (arrhythmia prevention [AP] group, n = 45) and with epinephrine (shock prevention [SP] group, n = 49), respectively." | 7.79 | Prophylactic amiodarone and lidocaine improve survival in an ovine model of large size myocardial infarction. ( Griffith, BP; Li, T; Sanchez, PG; Watkins, AC; Wei, X; Wu, ZJ, 2013) |
| "To compare the efficacy and safety of nifekalant, a pure class III anti-arrhythmic drug, and lidocaine in patients with shock-resistant in-hospital ventricular fibrillation (VF) or ventricular tachycardia (VT)." | 7.76 | Nifekalant versus lidocaine for in-hospital shock-resistant ventricular fibrillation or tachycardia. ( Amino, M; Honda, T; Kasanuki, H; Kato, R; Katoh, T; Matsudo, Y; Ogawa, S; Sagara, K; Shiga, T; Takahashi, A; Takano, T; Tanaka, K; Urashima, M, 2010) |
| "The antiarrhythmic action of the newly developed compound 44Bu (an original compound that was synthesized at our Faculty of Pharmacy) was tested on a model of aconitine-induced arrhythmia and compared with the effect of lidocaine." | 7.74 | Antiarrhythmic effect of newly synthesized compound 44Bu on model of aconitine-induced arrhythmia -- compared to lidocaine. ( Bartosova, L; Bebarova, M; Brunclik, V; Frydrych, M; Kolevska, J; Kollar, P; Mokry, P; Novak, F; Opatrilova, R; Strnadova, V; Suchy, P, 2007) |
| "As compared with lidocaine, nifekalant may improve short-term survival in patients with out-of-hospital cardiac arrest due to shock-refractory ventricular fibrillation." | 7.73 | Comparison of nifekalant and lidocaine for the treatment of shock-refractory ventricular fibrillation. ( Ebina, T; Hibi, K; Kimura, K; Kosuge, M; Kosuge, T; Moriwaki, Y; Sugiyama, M; Sumita, S; Suzuki, N; Tahara, Y; Toyama, H; Umemura, S, 2006) |
| "We performed a pilsicainide challenge test in a 38-year-old man who was resuscitated from ventricular fibrillation without apparent baseline electrocardiogram (ECG) abnormality." | 7.73 | Spontaneous polymorphic ventricular tachycardia after administration of pilsicainide in a patient resuscitated from ventricular fibrillation. ( Araki, S; Ogawa, H; Sadanaga, T; Tanaka, Y, 2006) |
| "A 56-year-old man with Brugada syndrome presented with ventricular fibrillation induced by administration of pilsicainide." | 7.72 | [Brugada syndrome associated with ventricular fibrillation induced by administration of pilsicainide: a case report]. ( Ebina, T; Ishikawa, T; Kimura, K; Kobayashi, T; Matsumoto, K; Matsushita, K; Mochida, Y; Nakagawa, T; Nakazawa, I; Ohkusu, Y; Sumita, S; Uchino, K; Umemura, S; Yamakawa, Y, 2003) |
| "Ventricular fibrillation (VF) is a cause of death in bupivacaine-induced cardiovascular toxicity." | 7.70 | Lidocaine increases the ventricular fibrillation threshold during bupivacaine-induced cardiotoxicity in pigs. ( Endoh, S; Fujita, Y; Sari, A; Yasukawa, T, 1998) |
| "The authors studied the effects of lidocaine in 18 consecutive dogs with myocardial infarction 1 to 4 days after two-stage left anterior descending coronary artery ligation." | 7.69 | Facilitation of reentry by lidocaine in canine myocardial infarction. ( Fazekas, T; Lazzara, R; Mabo, P; Patterson, E; Scherlag, BJ, 1994) |
| "The aim of the present study was to investigate the effect of lidocaine (L) on ventricular tachyarrhythmias with special reference to ventricular fibrillation (VF)." | 7.69 | Lidocaine converts inducible ventricular fibrillation into sustained ventricular tachycardia in conscious dogs with recent myocardial infarction. ( Aidonidis, I; Brachmann, J; Kübler, W; Rizos, I; Toutouzas, P, 1994) |
| " Lidocaine was then given to prolong the ventricular fibrillation cycle length, and the computerized mapping studies were repeated." | 7.69 | The effects of lidocaine on the vulnerable period during ventricular fibrillation. ( Cha, YM; Chen, PS; Peters, BB, 1994) |
| "The aim of this study was to evaluate the efficacy of a single dose of intravenous amiodarone in facilitating defibrillation of ventricular fibrillation refractory to lidocaine and epinephrine plus direct current countershocks in experimental acute myocardial infarction." | 7.69 | Effects of amiodarone on refractory ventricular fibrillation in acute myocardial infarction: experimental study. ( Anastasiou-Nana, MI; Moulopoulos, SD; Nanas, JN; Nanas, SN; Poyadjis, A; Rapti, A; Stathaki, S, 1994) |
| "We compared the ability of a new amiodarone-like agent, SR 33589, with that of amiodarone, D,L-sotalol, and lignocaine to reduce the incidence of ventricular fibrillation (VF) and associated arrhythmias caused by acute coronary artery occlusion in anesthetized pigs." | 7.69 | Effects of a new amiodarone-like agent, SR 33589, in comparison to amiodarone, D,L-sotalol, and lignocaine, on ischemia-induced ventricular arrhythmias in anesthetized pigs. ( Chatelain, P; Finance, O; Manning, A, 1995) |
| "We have assessed the ability of the new amiodarone-like antiarrhythmic agent, SR 33589, to reduce the incidence of ischemia- and reperfusion-induced arrhythmias, in comparison to amiodarone, D-sotalol, and lignocaine." | 7.69 | SR 33589, a new amiodarone-like agent: effect on ischemia- and reperfusion-induced arrhythmias in anesthetized rats. ( Bruyninckx, C; Chatelain, P; Manning, AS; Ramboux, J, 1995) |
| "To describe the proportion of patients with witnessed out-of-hospital cardiac arrest found in ventricular fibrillation who survived and were discharged from hospital in relation to whether they were treated with lidocaine prior to hospital admission." | 7.69 | Lidocaine in out-of-hospital ventricular fibrillation. Does it improve survival? ( Axelsson, A; Bång, A; Ekström, L; Herlitz, J; Holmberg, S; Lindkvist, J; Persson, NG; Wennerblom, B, 1997) |
| "Lidocaine addition to crystalloid cardioplegic solution for prevention of reperfusion ventricular fibrillation after the release of the aortic cross-clamp was studied in 50 patients undergoing coronary artery bypass grafting and in 30 patients undergoing mitral or aortic valve replacement." | 7.68 | Lidocaine cardioplegia for prevention of reperfusion ventricular fibrillation. ( Baraka, A; Dabbous, A; el-Khoury, N; Ghabash, M; Hirt, N; Jamhoury, M; Rouhana, C; Sibaii, A; Taha, S, 1993) |
| "The purposes of the present investigation were 1) to track the incidence of primary ventricular fibrillation (VF) in the control and lidocaine-treated groups in the randomized control trials (RCTs) of lidocaine prophylaxis against primary VF in acute myocardial infarction, with particular emphasis on the time frame of the randomized trial, and 2) to estimate the number of patients who must receive lidocaine currently to prevent one episode of VF." | 7.68 | Declining incidence of ventricular fibrillation in myocardial infarction. Implications for the prophylactic use of lidocaine. ( Antman, EM; Berlin, JA, 1992) |
| "The electrophysiological effects of lidocaine (L) and propafenone (P) in chronic myocardial infarction in relation to tissue drug concentrations (TDC) are unknown." | 7.67 | Epicardial, endocardial and transmural mapping in assessing electrophysiological effects of 14-C lidocaine and 14-C propafenone on activation times in experimental chronic myocardial infarction. Correlations with myocardial drugs concentrations. ( Agarwal, JB; Bracchetti, D; Helfant, RH; Naccarella, FF; Weintraub, WS, 1984) |
| "During the initial hospitalization, ventricular fibrillation (VF) developed in 6 metoprolol-treated patients (0." | 7.67 | Göteborg Metoprolol Trial: effects on arrhythmias. ( Edvardsson, N; Herlitz, J; Hjalmarson, A; Holmberg, S; Rydén, L; Swedberg, K; Waagstein, F; Waldenström, A, 1984) |
| "Metoprolol and other beta-adrenergic blocking drugs are known to exert cardioprotective effects that include significant reduction in occurrence of ventricular fibrillation (VF) following myocardial ischemia and infarction." | 7.67 | Effects of metoprolol, alone and in combination with lidocaine, on ventricular fibrillation threshold: comparison with atenolol, propranolol, and pindolol. ( Beil, ME; Cabot, CF; Coram, WM; Olson, RW; Weiss, GB, 1987) |
| "In the present study, we evaluated the antiarrhythmic interaction (s) of metoprolol and lidocaine in 16 dogs using the ventricular fibrillation threshold (VFT) method." | 7.67 | Interaction of metoprolol and lidocaine on the ventricular fibrillation threshold in the anesthetized dog. ( Balke, CW; de Langen, CD; Levine, JH; Moore, EN; Spear, JF, 1988) |
| "Tocainide was administered to 228 patients referred for treatment of recurrent ventricular tachyarrhythmias that were refractory to therapy with conventional antiarrhythmic drugs." | 7.67 | Short- and long-term therapy with tocainide for malignant ventricular tachyarrhythmias. ( Hohnloser, SH; Lange, HW; Lown, B; Podrid, PJ; Raeder, EA, 1986) |
| "The effects of lidocaine, tocainide and mexiletine were examined in 17 patients with coronary artery disease and chronic, recurrent, sustained ventricular tachycardia (VT) or ventricular fibrillation and inducible VT." | 7.67 | Efficacy of class Ib (lidocaine-like) antiarrhythmic agents for prevention of sustained ventricular tachycardia secondary to coronary artery disease. ( Easley, AR; Mann, DE; Reiter, MJ, 1987) |
| "Eighty-two patients with drug-resistant ventricular tachycardia or fibrillation were treated with oral tocainide." | 7.67 | Tocainide for drug-resistant sustained ventricular tachyarrhythmias. ( Adhar, GC; Bardy, GH; Clay, D; Greene, HL; Lance, BL; Swerdlow, CD, 1988) |
| "Ventricular fibrillation threshold was determined using a train of pulses, 4 ms in duration, delivered at 10 ms intervals, in 20 anaesthetised dogs receiving toxic doses of quinidine sulphate (30 mg X kg-1) injected intravenously over 5 min to prolong the QT interval." | 7.67 | Ventricular fibrillation threshold in canine hearts with quinidine induced prolonged QT interval: effects of atrial pacing, isoproterenol, and lignocaine. ( Inoue, H; Mashima, S; Matsuo, H; Murao, S; Sugimoto, T, 1986) |
| "In this study, we prospectively evaluated the effect of oral cimetidine on serum lidocaine concentrations in 6 patients with suspected myocardial infarction." | 7.67 | The effect of oral cimetidine on total and unbound serum lidocaine concentrations in patients with suspected myocardial infarction. ( Bauman, JL; Berk, SI; Douglas, JB; Gal, P; McCue, JD; Powell, JR, 1987) |
| "Prehospital prevention of primary ventricular fibrillation using 400 mg lidocaine i." | 7.67 | Lidocaine and prevention of ventricular fibrillation complicating acute myocardial infarction. ( Lie, KI, 1985) |
| "Forty-three patients in the acute phase of myocardial infarction who were resistant to conventional doses of lidocaine received Ajmaline intravenously (50 mg bolus followed by constant infusion rate of 1-1." | 7.66 | The efficacy of Ajmaline in ventricular arrhythmias after failure of lidocaine therapy in the acute phase of myocardial infarction. ( Alpan, G; Grenadier, E; Keidar, S; Marmor, A; Palant, A; Weiss, D, 1983) |
| "Tocainide, an oral form of lidocaine, was employed in 120 patients with recurrent malignant ventricular arrhythmia refractory to conventional antiarrhythmic drugs." | 7.66 | Tocainide for refractory symptomatic ventricular arrhythmias. ( Lown, B; Podrid, PJ, 1982) |
| " We therefore studied the effects of diltiazem and reduced serum ionized calcium on ventricular fibrillation (VF) in a reversible ligation model." | 7.66 | The effects of diltiazem and reduced serum ionized calcium on ischemic ventricular fibrillation in the dog. ( Baim, DS; Brett, P; Bristow, MR; Clusin, WT; Harrison, DC; Jaillon, P; Schroeder, JS, 1982) |
| "Because of recent recommendations that lidocaine be used prophylactically in all coronary care unit (CCU) patients with suspected myocardial infarction (MI), an approach not used in our CCU, we analysed our experience with ventricular fibrillation (VF) occurring in the setting of an acute MI." | 7.66 | Ventricular fibrillation complicating acute myocardial infarction: reasons against the routine use of lidocaine. ( Carruth, JE; Silverman, ME, 1982) |
| "Drug management of out-of-hospital countershock refractory ventricular fibrillation was evaluated by including 100 mg lidocaine bolus intravenously as the only anti-arrhythmic option in a protocol for use by paramedics." | 7.66 | Lidocaine in prehospital countershock refractory ventricular fibrillation. ( Harrison, EE, 1981) |
| " The new strategy has been illustrated in a case-control investigation of whether lidocaine prophylaxis prevents death in patients with acute myocardial infarction." | 7.66 | Improved observational method for studying therapeutic efficacy. Suggestive evidence that lidocaine prophylaxis prevents death in acute myocardial infarction. ( Feinstein, AR; Horwitz, RI, 1981) |
| "This study was performed to investigate the prophylactic effect of disopyramide phosphate on ventricular fibrillation in acute myocardial infarction." | 7.66 | Studies on the preventive method of lowered ventricular fibrillation threshold during experimental acute myocardial infarctions. A comparison between disopyramide phosphate and lidocaine. ( Fukuzaki, H; Hatani, M; Hori, Y; Imai, N; Nadai, T; Okamoto, R; Takano, S; Toh, H, 1981) |
| "Lidocaine is most widely used for suppression of recurrent ventricular tachyarrhythmias by IV application." | 7.66 | [Therapy of ventricular tachyarrhythmias refractory to lidocaine with propafenone (author's transl)]. ( Glogar, D; Laimer, H; Zilcher, H, 1981) |
| "We studied the effects of bretylium tosylate and lidocaine on ventricular fibrillation in the isolated, perfused rabbit heart induced by perfusion with potassium-deficient solutions and by premature stimuli." | 7.65 | Effects of bretylium and lidocaine on ventricular fibrillation in the isolated rabbit heart. ( Aravindakshan, V; Gettes, LS, 1975) |
| "The effect of lidocaine on the atrial fibrillation threshold (AFT) and the ventricular fibrillation threshold (VFT) was studied in anesthetized dogs." | 7.65 | Effect of lidocaine on the atrial fibrillation threshold. ( Gerber, NH; Goodking, MJ; Gotzoyannis, S; Kostis, JB; Kuo, PT, 1977) |
| "Several studies have questioned the efficacy of lidocaine in reducing the incidence of ventricular fibrillation shortly after acute myocardial infarction when arrhythmogenic mechanisms may be different from those operative several hours later." | 7.65 | Beneficial effect of lidocaine on ventricular electrical stability and spontaneous ventricular fibrillation during experimental myocardial infarction. ( Borer, JS; Epstein, SE; Goldstein, RE; Harrison, LA; Kent, KM; Levy, R, 1976) |
| "Ventricular fibrillation is common after aortic declamping in patients undergoing open heart surgery." | 6.79 | The effect of lidocaine and amiodarone on prevention of ventricular fibrillation in patients undergoing coronary artery bypass grafting. ( Arslan, ZI; Ata, Y; Aydin, U; Balcı, C; Kocogullari, CU; Turk, T; Yilmaz, M, 2014) |
| "The effects of prophylactic lidocaine hydrochloride on early ventricular fibrillation and death in patients with suspected acute myocardial infarction were investigated in an overview of 14 randomized trials." | 6.16 | Effects of prophylactic lidocaine in suspected acute myocardial infarction. An overview of results from the randomized, controlled trials. ( Collins, R; Koster, RW; MacMahon, S; Peto, R; Yusuf, S, 1988) |
| "Background The effects of amiodarone and lidocaine on the return of spontaneous circulation (ROSC) in relation to time to treatment in patients with out-of-hospital cardiac arrest is not known." | 5.51 | Effect of Time to Treatment With Antiarrhythmic Drugs on Return of Spontaneous Circulation in Shock-Refractory Out-of-Hospital Cardiac Arrest. ( Cheskes, S; Dorian, P; Lebovic, G; Lin, S; Rahimi, M, 2022) |
| "Ventricular fibrillation was induced in 16 pigs, and circulatory arrest was maintained for 14 minutes." | 5.40 | Effects of potassium/lidocaine-induced cardiac standstill during cardiopulmonary resuscitation in a pig model of prolonged ventricular fibrillation. ( Heo, T; Hun Jung, Y; Il Min, Y; Jeong, IS; Joon Lee, S; Kook Lee, B; Lim, V; Woon Jeung, K; Youn Lee, H, 2014) |
| "Ventricular fibrillation is a complication in patients hospitalized for acute myocardial infarction." | 5.29 | Sixty-six episodes of ventricular fibrillation within four hours: electrical stability restored by propafenone. ( Bellone, P; Spirito, P; Vecchio, C, 1994) |
| "A comparative study of two arrhythmia models was carried out using coronary ligation and reperfusion in anesthetized rats and in isolated rat hearts." | 5.27 | Coronary ligation-reperfusion arrhythmia models in anesthetized rats and isolated perfused rat hearts concentration-effect relationships of lidocaine. ( Follath, F; Ha, HR; Hof, RP; Uematsu, T; Vozeh, S, 1986) |
| "Lidocaine did not inhibit the binding of the lysophospholipid to the red cell membrane, but inhibited hemolysis in a manner similar to cholesterol." | 5.27 | The effect of lidocaine on lysophosphatidylcholine-induced cardiac arrhythmias and cellular disturbances. ( Choy, PC; Lederman, CL; Man, RY; Neufeld, KJ, 1985) |
| "In this randomized, double-blind trial, we compared parenteral amiodarone, lidocaine, and saline placebo, along with standard care, in adults who had nontraumatic out-of-hospital cardiac arrest, shock-refractory ventricular fibrillation or pulseless ventricular tachycardia after at least one shock, and vascular access." | 5.22 | Amiodarone, Lidocaine, or Placebo in Out-of-Hospital Cardiac Arrest. ( Aufderheide, TP; Brienza, AM; Brown, SP; Callaway, CW; Christenson, J; Colella, MR; Daya, M; Desvigne-Nickens, P; Dorian, P; Dunford, JV; Egan, D; Gray, PC; Gray, R; Idris, AH; Kudenchuk, PJ; Leroux, B; Morrison, LJ; Nichol, G; Ornato, JP; Rea, T; Seals, N; Stiell, IG; Straight, R; Vaillancourt, C; Vilke, GM; Weisfeldt, ML; Wittwer, L, 2016) |
| " We investigated the association between spontaneous ventricular fibrillation (VF) occurrence and TWA after pilsicainide, a sodium channel blocker administration in BS patients." | 5.13 | Clinical significance of macroscopic T-wave alternans after sodium channel blocker administration in patients with Brugada syndrome. ( Banba, K; Kusano, KF; Miura, D; Morita, H; Nagase, S; Nakamura, K; Nishii, N; Ohe, T; Tada, T; Watanabe, A, 2008) |
| "We aimed to compare the efficacy of sotalol versus lignocaine for the treatment of patients with out-of-hospital ventricular fibrillation refractory to > or = 4 defibrillatory shocks." | 5.11 | Randomized double-blind trial of sotalol versus lignocaine in out-of-hospital refractory cardiac arrest due to ventricular tachyarrhythmia. ( Adelstein, BA; Hall, J; Ho, D; Kovoor, P; Kruit, R; Love, A; Ross, DL; Sadick, N, 2005) |
| "As compared with lidocaine, amiodarone leads to substantially higher rates of survival to hospital admission in patients with shock-resistant out-of-hospital ventricular fibrillation." | 5.10 | Amiodarone as compared with lidocaine for shock-resistant ventricular fibrillation. ( Barr, A; Cass, D; Cooper, R; Dorian, P; Gelaznikas, R; Schwartz, B, 2002) |
| "Early meta-analyses suggested that prophylactic lidocaine use reduces ventricular fibrillation but increases mortality rates after acute myocardial infarction." | 5.09 | Prophylactic lidocaine use in acute myocardial infarction: incidence and outcomes from two international trials. The GUSTO-I and GUSTO-IIb Investigators. ( Alexander, JH; Aylward, PE; Califf, RM; Granger, CB; Sadowski, Z; Thompson, TD; Topol, EJ; White, HD, 1999) |
| "To determine the efficacy of a bolus of lidocaine administered by way of the pump before releasing the aortic cross-clamp (ACC) in preventing the occurrence of reperfusion ventricular fibrillation." | 5.09 | Lidocaine for prevention of reperfusion ventricular fibrillation after release of aortic cross-clamping. ( Baraka, A; Dabbous, A; Kawkabani, N; Nawfal, M, 2000) |
| "New congestive heart failure developed during the randomized phase in 9% of patients receiving lidocaine and in 2% of patients receiving placebo (p = 0." | 5.08 | Lidocaine prophylaxis for fatal ventricular arrhythmias after acute myocardial infarction. ( Chow, M; Fisher, J; Kluger, J; O'Rangers, E; Pharand, C; Ujhelyi, M, 1995) |
| "The efficacy of lidocaine to prevent ventricular fibrillation during the prehospital phase of suspected acute myocardial infarction was assessed 3 hours after administration in a randomized controlled trial." | 5.07 | Lidocaine to prevent ventricular fibrillation in the prehospital phase of suspected acute myocardial infarction: the North-Norwegian Lidocaine Intervention Trial. ( Berntsen, RF; Rasmussen, K, 1992) |
| "To compare the effects of Lidocaine (LID) alone or with Magnesium Sulfate (M) on life-threatening ventricular arrhythmias which followed cardioverted prolonged ventricular fibrillation (VF) during an acute myocardial infarction (AMI), we studied 34 (24." | 5.07 | Life-threatening arrhythmias after intravenous lidocaine alone or with magnesium in myocardial infarction complicated by ventricular fibrillation. ( Bertanelli, F; Fabiano, P; Leone, A; Mori, L, 1991) |
| "The authors compared bretylium and lidocaine for reducing the incidence and persistence of ventricular fibrillation following aortic cross-clamp release performed during coronary artery bypass surgery." | 5.06 | Comparison of bretylium and lidocaine in the prevention of ventricular fibrillation after aortic cross-clamp release in coronary artery bypass surgery. ( Briggs, R; Goglin, W; Grishkin, B; Helsel, R; Kirlangitis, J; Knight, R; Middaugh, R, 1990) |
| "One hundred ninety-nine patients with out-of-hospital cardiac arrest persisted in ventricular fibrillation after the first defibrillation attempt and were then randomly assigned to receive either epinephrine or lidocaine before the next two shocks." | 5.06 | Effect of epinephrine and lidocaine therapy on outcome after cardiac arrest due to ventricular fibrillation. ( Cobb, LA; Copass, MK; Fahrenbruch, CE; Hallstrom, AP; Johnson, DD; Weaver, WD, 1990) |
| "The prophylactic use of lidocaine in the patient with cardiac chest pain has been reported to reduce the incidence of sudden death from ventricular dysrhythmias in the hospital setting, but few studies have been done in the early prehospital phase." | 5.06 | Prophylactic lidocaine in the prehospital patient with chest pain of suspected cardiac origin. ( Aprahamian, C; Darin, J; Hargarten, KM; Mateer, JR; Stueven, HA; Thompson, BM, 1986) |
| "Within six hours of suspected acute myocardial infarction, 791 patients entered a randomised double blind study of combined intravenous and oral tocainide for the prophylaxis of primary ventricular fibrillation." | 5.05 | Prophylaxis of primary ventricular fibrillation with tocainide in acute myocardial infarction. ( Campbell, RW; Elton, RA; Goodfellow, RM; Hutton, I; Taylor, E, 1983) |
| "To study the efficacy of prophylactic lidocaine treatment on the genesis of ventricular tachyarrhythmias following recanalization of an occluded coronary artery, 49 patients with an acute myocardial infarction were studied." | 5.05 | [Ineffective use of lidocaine in preventing reperfusion arrhythmias in patients with acute myocardial infarct]. ( Jannasch, B; Kuck, KH; Mathey, DG; Schlüter, M; Schofer, J, 1985) |
| "Four hundred two patients with suspected myocardial infarction seen within 6 hours of the onset of symptoms entered a double-blind randomized trial of lidocaine vs placebo." | 5.05 | Prophylactic lidocaine in the early phase of suspected myocardial infarction. ( Adgey, AA; Campbell, NP; Dunn, HM; Kinney, CD; MacKenzie, G; McComb, JM; Shanks, RG, 1985) |
| "In a randomized controlled study examining the value of an intramuscular injection of lidocaine in the prehospitalization phase of suspected acute myocardial infarction, paramedics used an automatic injector to administer 400 mg of the drug into the patient's deltoid muscle before transport to the hospital." | 5.05 | Intramuscular lidocaine for prevention of lethal arrhythmias in the prehospitalization phase of acute myocardial infarction. ( Dunning, AJ; Koster, RW, 1985) |
| "The effectiveness of intramuscular lidocaine in preventing in-hospital primary ventricular fibrillation within 1 hour after injection of the drug in patients with acute myocardial infarction was assessed in a double-blind randomized study performed in 300 such patients admitted within 6 hours of myocardial infarction." | 5.04 | Efficacy of lidocaine in preventing primary ventricular fibrillation within 1 hour after a 300 mg intramuscular injection. A double-blind, randomized study of 300 hospitalized patients with acute myocardial infarction. ( Durrer, D; Janse, MJ; Lie, KI; Liem, KL; Louridtz, WJ; Willebrands, AF, 1978) |
| "In a double blind study performed in cooperation with 69 emergency doctors and general practitioners in the catchment areas of the university and of the city hospital in Lübeck the action of intramuscular lidocaine on mortality and on the incidence of arrhythmias was investigated in patients with acute myocardial infarction aged less than 70 years." | 5.04 | [Lidocaine prophylaxis in the pre-hospital phase of acute myocardial infarction (author's transl)]. ( Diederich, KW; Djonlagić, H; Fassl, H; Floor-Wieringa, A; Oltmanns, D, 1979) |
| "We identified three articles addressing lidocaine versus amiodarone in cardiac arrest: 1) a prospective study assessing lidocaine versus amiodarone for refractory ventricular fibrillation in out-of-hospital adults; 2) an observational retrospective cohort study of inpatient pediatric patients with ventricular fibrillation or pulseless ventricular tachycardia who received lidocaine, amiodarone, neither or both; and 3) a prospective study of ventricular tachycardia with a pulse in adults." | 4.95 | Amiodarone Versus Lidocaine for Pediatric Cardiac Arrest Due to Ventricular Arrhythmias: A Systematic Review. ( Atkins, DL; De Caen, AR; Lopez-Herce, J; Marino, BS; McBride, ME; Webster, G; Ziegler, CP, 2017) |
| "To determine the clinical effectiveness and safety of prophylactic lidocaine in preventing death among people with myocardial infarction." | 4.91 | Prophylactic lidocaine for myocardial infarction. ( Anand, V; Bangdiwala, S; Martí-Carvajal, AJ; Simancas-Racines, D, 2015) |
| "Biphasic defibrillation and intravenous amiodarone are useful in shock-resistant ventricular fibrillation." | 4.82 | Strategies for reversing shock-resistant ventricular fibrillation. ( Dorian, P; Sarkozy, A, 2003) |
| " A second prospective, randomized clinical trial of amiodarone for refractory ventricular fibrillation has again shown positive results in improving survival to hospital admission." | 4.82 | Cardiopulmonary Resuscitation Guidelines 2000 update: what's happened since? ( Kern, KB; Xavier, LC, 2003) |
| "The prophylactic administration of lidocaine for the prevention of primary ventricular fibrillation (VF) following suspected acute myocardial infarction (MI) is controversial." | 4.78 | Lidocaine prophylaxis in acute myocardial infarction. ( Tisdale, JE, 1991) |
| "There appears to be a theoretical basis for the use of lidocaine in treating ventricular arrhythmias secondary to acute ischemia largely based on voltage- and pH-dependent binding and inactivation of sodium channels by lidocaine under ischemic conditions." | 4.78 | Reconsiderations of the routine and preferential use of lidocaine in the emergent treatment of ventricular arrhythmias. ( Resh, W; Wesley, RC; Zimmerman, D, 1991) |
| "In acute myocardial infarction, lidocaine is considered the drug of choice for the treatment of malignant ventricular arrhythmias." | 4.78 | Lidocaine in the early phase of acute myocardial infarction: the controversy over prophylactic or selective use. ( Just, H; Kasper, W; Zehender, M, 1990) |
| " Early and adequate intravenous antiarrhythmic prophylaxis with lidocaine to raise the fibrillation threshold in the setting of coronary insufficiency can prevent primary ventricular fibrillation." | 4.75 | The management of acute coronary insufficiency. ( Baker, J; Greenfield, JC; Wagner, GS, 1977) |
| "American Heart Association Advanced Cardiac Life Support (ACLS) guidelines support the use of either amiodarone or lidocaine for cardiac arrest caused by ventricular tachycardia or ventricular fibrillation (VT/VF) based on studies of out-of-hospital cardiac arrest." | 4.31 | Comparative Effectiveness of Amiodarone and Lidocaine for the Treatment of In-Hospital Cardiac Arrest. ( Bradley, SM; Cranford, JA; Kronick, SL; Nawer, H; Neumar, RW; Wagner, D, 2023) |
| "To describe arrhythmias associated with administration of lidocaine in dogs treated for supraventricular tachyarrhythmias." | 4.12 | Rhythm disturbances associated with lidocaine administration in four dogs with supraventricular tachyarrhythmias. ( Connolly, DJ; Luis Fuentes, V; Porteiro Vázquez, DM; Seo, J; Spalla, I; Tinson, E, 2022) |
| "Clinical trials for patients with shock-refractory out-of-hospital cardiac arrest (OHCA), including the Amiodarone, Lidocaine or Placebo (ALPS) trial, have been unable to demonstrate definitive benefit after treatment with antiarrhythmic drugs." | 4.12 | Bayesian analysis of amiodarone or lidocaine versus placebo for out-of-hospital cardiac arrest. ( Christenson, J; Davis, D; Daya, MR; Dorian, P; Grunau, B; Kudenchuk, P; Lane, DJ; Lupton, J; Okubo, M; Rea, T; Scheuermeyer, F; Vaillancourt, C; Wang, HE; Yannopoulos, D, 2022) |
| " We present a case secondary to Chagas disease that was responsive to lidocaine." | 4.12 | The imperfect storm: An uncommon presentation of Chagas disease. ( Johnson, MC; Wang, L, 2022) |
| " We included adult patients with shockable rhythms, such as ventricular fibrillation and pulseless ventricular tachycardia, who were administered either lidocaine or amiodarone." | 4.12 | Comparison of the effects of lidocaine and amiodarone for out-of-hospital cardiac arrest patients with shockable rhythms: a retrospective observational study from a multicenter registry. ( Amagasa, S; Fukushima, F; Kashiura, M; Kishihara, Y; Moriya, T; Yasuda, H, 2022) |
| "International guidelines recommend amiodarone for out-of-hospital cardiac arrest (OHCA) in refractory ventricular fibrillation (VF)." | 4.02 | Time to amiodarone administration and survival outcomes in refractory ventricular fibrillation. ( Bosley, E; Doan, TN; Rashford, S; Schultz, BV; Wilson, D; Wissa, J, 2021) |
| "To determine the association between amiodarone or lidocaine and outcomes in adult in-hospital cardiac arrest (IHCA) with shock-refractory ventricular fibrillation (VF) or pulseless ventricular tachycardia (pVT)." | 3.96 | Outcomes associated with amiodarone and lidocaine for the treatment of adult in-hospital cardiac arrest with shock-refractory pulseless ventricular tachyarrhythmia. ( Chang, WT; Chen, WJ; Huang, CH; Liu, YB; Tsai, MS; Wang, CH; Wu, YW; Yu, PH, 2020) |
| "Active hydraulic ventricular attaching support system (ASD) placed around the heart is not only a novel, nontransplant surgical device used for epicardial administration of drugs like lidocaine, but also a promising treatment option for ventricular fibrillation (VF) and arrhythmias." | 3.91 | A novel approach to devise the therapy for ventricular fibrillation by epicardial delivery of lidocaine using active hydraulic ventricular attaching support system: An experimental study in rats. ( Chen, D; Ihsan, AU; Khan, FU; Li, C; Li, X; Liao, X; Mikrani, R; Sembatya, KR; Wang, Z; Yasmeen, S; Yu, F; Zhou, X, 2019) |
| "We administered intravenous pilsicainide to 245 consecutive patients with Brugada syndrome (181 patients with spontaneous type 1 ECG, 64 patients with non-type 1 ECG)." | 3.88 | Prognostic Significance of the Sodium Channel Blocker Test in Patients With Brugada Syndrome. ( Ito, H; Kawada, S; Miyamoto, M; Morimoto, Y; Morita, H; Nakagawa, K; Nishii, N; Tachibana, M; Ueoka, A; Watanabe, A, 2018) |
| "To determine the association between amiodarone and lidocaine and outcomes in children with cardiac arrest with pulseless ventricular tachycardia (pVT) and ventricular fibrillation (VF)." | 3.80 | Outcomes associated with amiodarone and lidocaine in the treatment of in-hospital pediatric cardiac arrest with pulseless ventricular tachycardia or ventricular fibrillation. ( Berg, MD; Berg, RA; Donoghue, AJ; Hammond, R; Hoyme, DB; Samson, RA; Valdes, SO, 2014) |
| "To compare the early postarrest inflammatory cytokine response between animals administered amiodarone (AMIO) and lidocaine (LIDO) intra-arrest during resuscitation from ventricular fibrillation (VF)." | 3.79 | Administration of amiodarone during resuscitation is associated with higher tumor necrosis factor-α levels in the early postarrest period in the swine model of ischemic ventricular fibrillation. ( Niemann, JT; Rosborough, JP; Shah, AP; Thomas, JL; Youngquist, ST, 2013) |
| "Antiarrhythmic drugs like lidocaine are usually given to promote return of spontaneous circulation (ROSC) during ongoing out-of-hospital cardiac arrest (OHCA) from ventricular fibrillation/tachycardia (VF/VT)." | 3.79 | Prophylactic lidocaine for post resuscitation care of patients with out-of-hospital ventricular fibrillation cardiac arrest. ( Eisenberg, M; Fahrenbruch, C; Kudenchuk, PJ; Newell, C; Rea, T; White, L, 2013) |
| " The sheep were prophylactically treated with amiodarone plus lidocaine before ligation of the four to six coronary artery branches supplying the apex of the heart (arrhythmia prevention [AP] group, n = 45) and with epinephrine (shock prevention [SP] group, n = 49), respectively." | 3.79 | Prophylactic amiodarone and lidocaine improve survival in an ovine model of large size myocardial infarction. ( Griffith, BP; Li, T; Sanchez, PG; Watkins, AC; Wei, X; Wu, ZJ, 2013) |
| "We conducted a retrospective analysis of ST-segment elevation myocardial infarction patients with sustained ventricular tachycardia/ventricular fibrillation in Global Use of Strategies to Open Occluded Coronary Arteries in Acute Coronary Syndromes (GUSTO) IIB and GUSTO III and compared all-cause death in patients receiving amiodarone, lidocaine, or no antiarrhythmic." | 3.77 | Antiarrhythmic drug therapy for sustained ventricular arrhythmias complicating acute myocardial infarction. ( Alexander, JH; Ardissino, D; Califf, RM; Granger, CB; Mehta, RH; Ohman, EM; Piccini, JP; Pieper, KS; Schulte, PJ; Van de Werf, F; White, HD, 2011) |
| "To compare the efficacy and safety of nifekalant, a pure class III anti-arrhythmic drug, and lidocaine in patients with shock-resistant in-hospital ventricular fibrillation (VF) or ventricular tachycardia (VT)." | 3.76 | Nifekalant versus lidocaine for in-hospital shock-resistant ventricular fibrillation or tachycardia. ( Amino, M; Honda, T; Kasanuki, H; Kato, R; Katoh, T; Matsudo, Y; Ogawa, S; Sagara, K; Shiga, T; Takahashi, A; Takano, T; Tanaka, K; Urashima, M, 2010) |
| "Pericardial lidocaine (1) decreased heart rate without affecting stroke volume, (2) preserved the tachycardiac response to isoproterenol but completely blocked the response to atropine, and (3) increased the voltage thresholds for arrhythmias and ventricular fibrillation induced by an electrical fibrillator." | 3.74 | Effects of pericardial lidocaine on hemodynamic parameters and responses in dogs anesthetized with midazolam and fentanyl. ( Akamatsu, S; Dohi, S; Suzuki, A; Takada, M, 2007) |
| "The antiarrhythmic action of the newly developed compound 44Bu (an original compound that was synthesized at our Faculty of Pharmacy) was tested on a model of aconitine-induced arrhythmia and compared with the effect of lidocaine." | 3.74 | Antiarrhythmic effect of newly synthesized compound 44Bu on model of aconitine-induced arrhythmia -- compared to lidocaine. ( Bartosova, L; Bebarova, M; Brunclik, V; Frydrych, M; Kolevska, J; Kollar, P; Mokry, P; Novak, F; Opatrilova, R; Strnadova, V; Suchy, P, 2007) |
| "As compared with lidocaine, nifekalant may improve short-term survival in patients with out-of-hospital cardiac arrest due to shock-refractory ventricular fibrillation." | 3.73 | Comparison of nifekalant and lidocaine for the treatment of shock-refractory ventricular fibrillation. ( Ebina, T; Hibi, K; Kimura, K; Kosuge, M; Kosuge, T; Moriwaki, Y; Sugiyama, M; Sumita, S; Suzuki, N; Tahara, Y; Toyama, H; Umemura, S, 2006) |
| "Antiarrhythmic properties of taurhythman were demonstrated on experimental models of ventricular (early occlusion and calcium chloride-induced) and atrioventricular (aconitine-induced) arrhythmias." | 3.73 | Antiarrhythmic activity of taurhythman. ( Evdokimova, NR; Gavrovskaya, LK; Krylova, IB; Sapronov, NS, 2005) |
| "We performed a pilsicainide challenge test in a 38-year-old man who was resuscitated from ventricular fibrillation without apparent baseline electrocardiogram (ECG) abnormality." | 3.73 | Spontaneous polymorphic ventricular tachycardia after administration of pilsicainide in a patient resuscitated from ventricular fibrillation. ( Araki, S; Ogawa, H; Sadanaga, T; Tanaka, Y, 2006) |
| "A 56-year-old man with Brugada syndrome presented with ventricular fibrillation induced by administration of pilsicainide." | 3.72 | [Brugada syndrome associated with ventricular fibrillation induced by administration of pilsicainide: a case report]. ( Ebina, T; Ishikawa, T; Kimura, K; Kobayashi, T; Matsumoto, K; Matsushita, K; Mochida, Y; Nakagawa, T; Nakazawa, I; Ohkusu, Y; Sumita, S; Uchino, K; Umemura, S; Yamakawa, Y, 2003) |
| ") reduced or completely abolished the ventricular fibrillation (VF) induced by reperfusion after 5 min of regional ischemia, while lidocaine, a class I antiarrhythmic agent, showed less effect against VF as compared with FR168888." | 3.70 | Protective effect of FR168888, a new Na+/H+ exchange inhibitor, on ischemia and reperfusion-induced arrhythmia and myocardial infarction in rats: in comparison with other cardioprotective compounds. ( Goto, T; Maeda, K; Ohara, F; Ohkubo, K; Ozaki, T; Seki, J; Sugimoto, T; Yamamoto, N, 1999) |
| " In nonischemic isolated feline hearts, the following electrophysiologic parameters were measured before and after application of tetrodotoxin (5 x 10(-7) M, n = 6) or lidocaine (1 x 10(-5) M, n = 8): (a) during pacing, epicardial conduction time; refractoriness; the fastest rate for 1:1 pacing/response capture, and all tissue resistivity, indirectly reflecting intercellular electrical resistance; (b) during 8 min of electrically induced tachyarrhythmias, all tissue resistivity; peak frequency (to measure average frequency based on fast-Fourier transformation analysis); and normalized entropy (to measure the degree of arrhythmia organization)." | 3.70 | Role of sodium channels in ventricular fibrillation: a study in nonischemic isolated hearts. ( Amitzur, G; Eldar, M; Kaplinsky, E; Kraft, P; Lev-Ran, V; Mueller, M; Novikov, I; Schoels, W; Visokovsky, A, 2000) |
| "The authors studied the effects of lidocaine in 18 consecutive dogs with myocardial infarction 1 to 4 days after two-stage left anterior descending coronary artery ligation." | 3.69 | Facilitation of reentry by lidocaine in canine myocardial infarction. ( Fazekas, T; Lazzara, R; Mabo, P; Patterson, E; Scherlag, BJ, 1994) |
| "Because recent clinical studies have failed to show evidence of the benefit of lidocaine in the arrhythmias occurring in the early stage of myocardial infarction and have even shown an increased mortality in patients thus treated, we investigated the value of lidocaine as a protective agent against ventricular fibrillation related to myocardial ischemia in the in situ heart of anesthetized open-chest pigs subjected to transient total occlusion of the proximal left anterior descending coronary artery (LAD) under ventricular pacing at a constant high rate." | 3.69 | Profibrillatory effects of lidocaine in the acutely ischemic porcine heart. ( Aupetit, JF; Barral-Cadière, L; Faucon, G; Freysz, M; Lopez, M; Loufoua-Moundanga, J; Timour, Q, 1995) |
| "The aim of the present study was to investigate the effect of lidocaine (L) on ventricular tachyarrhythmias with special reference to ventricular fibrillation (VF)." | 3.69 | Lidocaine converts inducible ventricular fibrillation into sustained ventricular tachycardia in conscious dogs with recent myocardial infarction. ( Aidonidis, I; Brachmann, J; Kübler, W; Rizos, I; Toutouzas, P, 1994) |
| " Lidocaine was then given to prolong the ventricular fibrillation cycle length, and the computerized mapping studies were repeated." | 3.69 | The effects of lidocaine on the vulnerable period during ventricular fibrillation. ( Cha, YM; Chen, PS; Peters, BB, 1994) |
| "Metaanalysis of data from 20 years of randomized trials of lidocaine prophylaxis in preventing primary ventricular fibrillation (VF) in myocardial infarction used separate data for control and active-treatment groups to model the risk of VF as a function of year of publication and other study characteristics." | 3.69 | Advantages and limitations of metaanalytic regressions of clinical trials data. ( Antman, EM; Berlin, JA, 1994) |
| "The aim of this study was to evaluate the efficacy of a single dose of intravenous amiodarone in facilitating defibrillation of ventricular fibrillation refractory to lidocaine and epinephrine plus direct current countershocks in experimental acute myocardial infarction." | 3.69 | Effects of amiodarone on refractory ventricular fibrillation in acute myocardial infarction: experimental study. ( Anastasiou-Nana, MI; Moulopoulos, SD; Nanas, JN; Nanas, SN; Poyadjis, A; Rapti, A; Stathaki, S, 1994) |
| "We compared the ability of a new amiodarone-like agent, SR 33589, with that of amiodarone, D,L-sotalol, and lignocaine to reduce the incidence of ventricular fibrillation (VF) and associated arrhythmias caused by acute coronary artery occlusion in anesthetized pigs." | 3.69 | Effects of a new amiodarone-like agent, SR 33589, in comparison to amiodarone, D,L-sotalol, and lignocaine, on ischemia-induced ventricular arrhythmias in anesthetized pigs. ( Chatelain, P; Finance, O; Manning, A, 1995) |
| "We have assessed the ability of the new amiodarone-like antiarrhythmic agent, SR 33589, to reduce the incidence of ischemia- and reperfusion-induced arrhythmias, in comparison to amiodarone, D-sotalol, and lignocaine." | 3.69 | SR 33589, a new amiodarone-like agent: effect on ischemia- and reperfusion-induced arrhythmias in anesthetized rats. ( Bruyninckx, C; Chatelain, P; Manning, AS; Ramboux, J, 1995) |
| "The primary objective of this study was to determine the effect of esmolol, administered alone and in combination with lidocaine, on ventricular fibrillation threshold (VFT) in pigs." | 3.69 | Antifibrillatory effect of esmolol alone and in combination with lidocaine. ( Chow, MS; Colucci, RD; Fan, CD; Kluger, J; Sun, H; Tisdale, JE; Zhao, H, 1996) |
| "To describe the proportion of patients with witnessed out-of-hospital cardiac arrest found in ventricular fibrillation who survived and were discharged from hospital in relation to whether they were treated with lidocaine prior to hospital admission." | 3.69 | Lidocaine in out-of-hospital ventricular fibrillation. Does it improve survival? ( Axelsson, A; Bång, A; Ekström, L; Herlitz, J; Holmberg, S; Lindkvist, J; Persson, NG; Wennerblom, B, 1997) |
| "The first-pass effect of dauricine (Dau) was compared with that of lidocaine (Lid) by measuring the ventricular fibrillation threshold (VFT) and dauricine plasma concentration in rats or rabbits." | 3.68 | [First-pass effect of dauricine]. ( Du, ZH; Gui, YT; Hu, CJ; Zeng, FD, 1993) |
| "Lidocaine addition to crystalloid cardioplegic solution for prevention of reperfusion ventricular fibrillation after the release of the aortic cross-clamp was studied in 50 patients undergoing coronary artery bypass grafting and in 30 patients undergoing mitral or aortic valve replacement." | 3.68 | Lidocaine cardioplegia for prevention of reperfusion ventricular fibrillation. ( Baraka, A; Dabbous, A; el-Khoury, N; Ghabash, M; Hirt, N; Jamhoury, M; Rouhana, C; Sibaii, A; Taha, S, 1993) |
| " The action of IHC-72 against aconitine induced arrhythmia was similar to that of Lid but stronger than that of Ver in anesthetized rats." | 3.68 | [Comparison of antiarrhythmic effects of IHC-72 (an iodonium-72), lidocaine and verapamil]. ( Ji, GJ; Liu, DQ; Sheng, BH; Zhao, DH, 1992) |
| "The purposes of the present investigation were 1) to track the incidence of primary ventricular fibrillation (VF) in the control and lidocaine-treated groups in the randomized control trials (RCTs) of lidocaine prophylaxis against primary VF in acute myocardial infarction, with particular emphasis on the time frame of the randomized trial, and 2) to estimate the number of patients who must receive lidocaine currently to prevent one episode of VF." | 3.68 | Declining incidence of ventricular fibrillation in myocardial infarction. Implications for the prophylactic use of lidocaine. ( Antman, EM; Berlin, JA, 1992) |
| "A potentially fatal arrhythmia was encountered in a patient with a previous myocardial infarction, who was resistant to treatment with lidocaine, amiodarone and electric defibrillation." | 3.68 | Stabilization of cardiac rhythm in subsequently fatal ventricular tachycardia and fibrillation by calcitonin gene-related peptide. ( Liu, J; Liu, XZ; Zhang, JF, 1992) |
| "Bretylium tosylate has been shown effective in the treatment of ventricular fibrillation and in the prevention of its recurrence." | 3.68 | Bretylium tosylate versus lidocaine in experimental cardiac arrest. ( Blecic, S; Contempré, B; Reuse, C; Vachiery, JL; Vincent, JL, 1990) |
| "Prevention of ventricular fibrillation after aortic unclamping using lidocaine hydrochloride as an additive to cold potassium blood cardioplegia was studied prospectively in 46 patients undergoing elective myocardial revascularization." | 3.68 | Myocardial preservation using lidocaine blood cardioplegia. ( Barner, HB; Braun, P; Fiore, AC; Kaiser, GC; McBride, LR; Naunheim, KS; Pennington, DG; Taub, J; Willman, VL, 1990) |
| "Prehospital prevention of primary ventricular fibrillation using 300 mg lidocaine intramuscularly seems to be ineffective in view of the rather low plasma lidocaine levels obtained with this regimen." | 3.67 | Pre- and in-hospital antiarrhythmic prevention of ventricular fibrillation complicating acute myocardial infarction. ( Lie, KI, 1984) |
| "The electrophysiological effects of lidocaine (L) and propafenone (P) in chronic myocardial infarction in relation to tissue drug concentrations (TDC) are unknown." | 3.67 | Epicardial, endocardial and transmural mapping in assessing electrophysiological effects of 14-C lidocaine and 14-C propafenone on activation times in experimental chronic myocardial infarction. Correlations with myocardial drugs concentrations. ( Agarwal, JB; Bracchetti, D; Helfant, RH; Naccarella, FF; Weintraub, WS, 1984) |
| "During the initial hospitalization, ventricular fibrillation (VF) developed in 6 metoprolol-treated patients (0." | 3.67 | Göteborg Metoprolol Trial: effects on arrhythmias. ( Edvardsson, N; Herlitz, J; Hjalmarson, A; Holmberg, S; Rydén, L; Swedberg, K; Waagstein, F; Waldenström, A, 1984) |
| "Metoprolol and other beta-adrenergic blocking drugs are known to exert cardioprotective effects that include significant reduction in occurrence of ventricular fibrillation (VF) following myocardial ischemia and infarction." | 3.67 | Effects of metoprolol, alone and in combination with lidocaine, on ventricular fibrillation threshold: comparison with atenolol, propranolol, and pindolol. ( Beil, ME; Cabot, CF; Coram, WM; Olson, RW; Weiss, GB, 1987) |
| "In the present study, we evaluated the antiarrhythmic interaction (s) of metoprolol and lidocaine in 16 dogs using the ventricular fibrillation threshold (VFT) method." | 3.67 | Interaction of metoprolol and lidocaine on the ventricular fibrillation threshold in the anesthetized dog. ( Balke, CW; de Langen, CD; Levine, JH; Moore, EN; Spear, JF, 1988) |
| "5 V, 750 ms) or programmed ventricular stimulation, creation of a small myocardial infarction, and application of antiarrhythmic drugs (ajmalin, lidocaine, sotalol)." | 3.67 | Acute induction of sustained ventricular tachycardia: a new porcine model. ( Lüderitz, B; Nitsch, J; Schmid, C, 1989) |
| "Tocainide was administered to 228 patients referred for treatment of recurrent ventricular tachyarrhythmias that were refractory to therapy with conventional antiarrhythmic drugs." | 3.67 | Short- and long-term therapy with tocainide for malignant ventricular tachyarrhythmias. ( Hohnloser, SH; Lange, HW; Lown, B; Podrid, PJ; Raeder, EA, 1986) |
| "The effect of intravenous lidocaine, 2 mg/kg, and bretylium, 5 mg/kg, on defibrillation threshold (DFT) was investigated in alpha-chloralose anesthetized dogs undergoing conventional closed chest cardiopulmonary resuscitation (CPR) following induced ventricular fibrillation." | 3.67 | The effect of lidocaine and bretylium on the defibrillation threshold during cardiac arrest and cardiopulmonary resuscitation. ( Chow, MS; Fieldman, A; Kluger, J; Lawrence, R, 1986) |
| "The effects of lidocaine, tocainide and mexiletine were examined in 17 patients with coronary artery disease and chronic, recurrent, sustained ventricular tachycardia (VT) or ventricular fibrillation and inducible VT." | 3.67 | Efficacy of class Ib (lidocaine-like) antiarrhythmic agents for prevention of sustained ventricular tachycardia secondary to coronary artery disease. ( Easley, AR; Mann, DE; Reiter, MJ, 1987) |
| "Eighty-two patients with drug-resistant ventricular tachycardia or fibrillation were treated with oral tocainide." | 3.67 | Tocainide for drug-resistant sustained ventricular tachyarrhythmias. ( Adhar, GC; Bardy, GH; Clay, D; Greene, HL; Lance, BL; Swerdlow, CD, 1988) |
| "Lidocaine for prevention of lethal arrhythmias in the prehospitalization phase of acute myocardial infarction has often been discussed controversially." | 3.67 | [Preventive use of lidocaine in the prehospital phase of acute myocardial infarct]. ( Dienstl, F; Lechleitner, P, 1987) |
| "Ventricular fibrillation threshold was determined using a train of pulses, 4 ms in duration, delivered at 10 ms intervals, in 20 anaesthetised dogs receiving toxic doses of quinidine sulphate (30 mg X kg-1) injected intravenously over 5 min to prolong the QT interval." | 3.67 | Ventricular fibrillation threshold in canine hearts with quinidine induced prolonged QT interval: effects of atrial pacing, isoproterenol, and lignocaine. ( Inoue, H; Mashima, S; Matsuo, H; Murao, S; Sugimoto, T, 1986) |
| "In this study, we prospectively evaluated the effect of oral cimetidine on serum lidocaine concentrations in 6 patients with suspected myocardial infarction." | 3.67 | The effect of oral cimetidine on total and unbound serum lidocaine concentrations in patients with suspected myocardial infarction. ( Bauman, JL; Berk, SI; Douglas, JB; Gal, P; McCue, JD; Powell, JR, 1987) |
| "Prehospital prevention of primary ventricular fibrillation using 400 mg lidocaine i." | 3.67 | Lidocaine and prevention of ventricular fibrillation complicating acute myocardial infarction. ( Lie, KI, 1985) |
| "The efficacy of verapamil and lidocaine for treating ischemia-induced arrhythmias was determined in a conscious canine model with a previous myocardial infarction remote from the ischemic area." | 3.67 | Effects of verapamil and lidocaine in a canine model of sudden coronary death. ( Hoffman, BF; Legenza, M; Southworth, SR; Temesy-Armos, PN, 1985) |
| "The antifibrillatory effects of lidocaine and bretylium in the postcardiopulmonary resuscitation (CPR) setting were examined using ventricular fibrillation threshold (VFT) determinations in anesthetized dogs." | 3.67 | Antifibrillatory effects of lidocaine and bretylium immediately postcardiopulmonary resuscitation. ( Chow, MS; DiPersio, DM; Fieldman, A; Kluger, J; Lawrence, R, 1985) |
| "The effectiveness of three new antiarrhythmic drugs, aprindine, mexiletine and tocainide in elevating ventricular fibrillation threshold measured in the Langendorff-perfused rabbit heart and in protecting against ouabain-induced arrhythmias in the Langendorff-perfused guinea-pig heart has been compared with that of lignocaine." | 3.66 | The antifibrillatory potency of aprindine, mexiletine, tocainide and lignocaine compared on Langendorff-perfused hearts of rabbits and guinea-pigs. ( Almotrefi, AA; Baker, JB, 1980) |
| "Forty-three patients in the acute phase of myocardial infarction who were resistant to conventional doses of lidocaine received Ajmaline intravenously (50 mg bolus followed by constant infusion rate of 1-1." | 3.66 | The efficacy of Ajmaline in ventricular arrhythmias after failure of lidocaine therapy in the acute phase of myocardial infarction. ( Alpan, G; Grenadier, E; Keidar, S; Marmor, A; Palant, A; Weiss, D, 1983) |
| "Tocainide, an oral form of lidocaine, was employed in 120 patients with recurrent malignant ventricular arrhythmia refractory to conventional antiarrhythmic drugs." | 3.66 | Tocainide for refractory symptomatic ventricular arrhythmias. ( Lown, B; Podrid, PJ, 1982) |
| " We therefore studied the effects of diltiazem and reduced serum ionized calcium on ventricular fibrillation (VF) in a reversible ligation model." | 3.66 | The effects of diltiazem and reduced serum ionized calcium on ischemic ventricular fibrillation in the dog. ( Baim, DS; Brett, P; Bristow, MR; Clusin, WT; Harrison, DC; Jaillon, P; Schroeder, JS, 1982) |
| "Because of recent recommendations that lidocaine be used prophylactically in all coronary care unit (CCU) patients with suspected myocardial infarction (MI), an approach not used in our CCU, we analysed our experience with ventricular fibrillation (VF) occurring in the setting of an acute MI." | 3.66 | Ventricular fibrillation complicating acute myocardial infarction: reasons against the routine use of lidocaine. ( Carruth, JE; Silverman, ME, 1982) |
| "The need to determine whether prophylactic lidocaine has any therapeutic value is generally recognized, and further investigations have been urged: A carefully designed clinical trial of routine lidocaine administration should be carried out to provide definitive information for the physician treating patients who have had myocardial infarction." | 3.66 | Prophylactic lidocaine: uncertain benefits in emergency settings. ( Borak, J; Veilleux, S, 1982) |
| " The new strategy has been illustrated in a case-control investigation of whether lidocaine prophylaxis prevents death in patients with acute myocardial infarction." | 3.66 | Improved observational method for studying therapeutic efficacy. Suggestive evidence that lidocaine prophylaxis prevents death in acute myocardial infarction. ( Feinstein, AR; Horwitz, RI, 1981) |
| "This study was performed to investigate the prophylactic effect of disopyramide phosphate on ventricular fibrillation in acute myocardial infarction." | 3.66 | Studies on the preventive method of lowered ventricular fibrillation threshold during experimental acute myocardial infarctions. A comparison between disopyramide phosphate and lidocaine. ( Fukuzaki, H; Hatani, M; Hori, Y; Imai, N; Nadai, T; Okamoto, R; Takano, S; Toh, H, 1981) |
| "Lidocaine is most widely used for suppression of recurrent ventricular tachyarrhythmias by IV application." | 3.66 | [Therapy of ventricular tachyarrhythmias refractory to lidocaine with propafenone (author's transl)]. ( Glogar, D; Laimer, H; Zilcher, H, 1981) |
| "A patient with severe tricyclic antidepressant poisoning who showed recurrent ventricular fibrillation and wide QRS complexes on the ECG, failed to respond to intravenous physostigmine and lidocaine." | 3.66 | Hyperventilation in tricyclic antidepressant poisoning. ( Kingston, ME, 1979) |
| " All compounds were evaluated for their ability to protect against chloroform-induced ventricular fibrillation in mice." | 3.65 | Isoquinolines. 5. Synthesis and antiarrhythmic activity of benzylisoquinoline derivatives. ( Neumeyer, JL; Perianayagam, C; Ruchirawat, S, 1977) |
| "We studied the effects of bretylium tosylate and lidocaine on ventricular fibrillation in the isolated, perfused rabbit heart induced by perfusion with potassium-deficient solutions and by premature stimuli." | 3.65 | Effects of bretylium and lidocaine on ventricular fibrillation in the isolated rabbit heart. ( Aravindakshan, V; Gettes, LS, 1975) |
| "The effect of lidocaine on the atrial fibrillation threshold (AFT) and the ventricular fibrillation threshold (VFT) was studied in anesthetized dogs." | 3.65 | Effect of lidocaine on the atrial fibrillation threshold. ( Gerber, NH; Goodking, MJ; Gotzoyannis, S; Kostis, JB; Kuo, PT, 1977) |
| "Several studies have questioned the efficacy of lidocaine in reducing the incidence of ventricular fibrillation shortly after acute myocardial infarction when arrhythmogenic mechanisms may be different from those operative several hours later." | 3.65 | Beneficial effect of lidocaine on ventricular electrical stability and spontaneous ventricular fibrillation during experimental myocardial infarction. ( Borer, JS; Epstein, SE; Goldstein, RE; Harrison, LA; Kent, KM; Levy, R, 1976) |
| " In anaesthetized guinea-pigs in which ventricular fibrillation had been produced by an intravenous infusion of ouabain, intravenous administration of Kö 1173 caused reversion to sinus rhythm in ten out of ten animals." | 3.65 | Investigations of the mode of action of a new antidysrhythmic drug, Kö 1173. ( Singh, BN; Vaughan Williams, EM, 1972) |
| " Routine use of intravenous sodium bicarbonate is recommended to combat the severe metabolic acidosis accompanying cardiac arrest." | 3.64 | THE CHEMOTHERAPY OF CARDIAC ARREST. ( MINUCK, M, 1965) |
| "An intravenous bolus injection and subsequent continuous infusion of NIF at a relatively low dosage were effective in treating severe ventricular tachyarrhythmias complicating ACS, reducing the potential risk of proarrhythmia." | 2.74 | Effects of intravenous nifekalant as a lifesaving drug for severe ventricular tachyarrhythmias complicating acute coronary syndrome. ( Abe, A; Ikeda, T; Ishiguro, H; Mera, H; Miwa, Y; Miyakoshi, M; Shimizu, H; Tsukada, T; Yoshino, H; Yusu, S, 2009) |
| "We analyzed the incidence and recurrence rate of early and late primary VF in 9,720 patients with a first acute MI, treated with thrombolytics, enrolled in the Gruppo Italiano per lo Studio della Sopravvivenza nell'Infarto Miocardico (GISSI)-2 trial." | 2.69 | Incidence and prognosis of early primary ventricular fibrillation in acute myocardial infarction--results of the Gruppo Italiano per lo Studio della Sopravvivenza nell'Infarto Miocardico (GISSI-2) database. ( Cavalli, A; Negri, E; Santoro, L; Volpi, A, 1998) |
| "Safe, effective prophylaxis of arrhythmias in acute myocardial infarction (AMI) is an important clinical goal." | 2.37 | Prophylactic antiarrhythmic therapy in acute myocardial infarction. ( Campbell, RW, 1984) |
| "Ventricular arrhythmias represent a common precursor of ventricular fibrillation in acute myocardial infarction in man." | 2.36 | [Prognostic significance of arrhythmias in acute myocardial infarction (author's transl)]. ( Breithardt, G; Loogen, F; Seipel, L, 1977) |
| "Awake patients in ventricular fibrillation is a phenomenon limited to patients who are mechanically supported." | 1.91 | Stable Ventricular Fibrillation: A Paradigm Rather Than Septal Shift? ( Bracy, CL; Gupta, R; Hockstein, MA; Hockstein, MJ; Kobres, PY; Lam, PH; Rao, SD; Sheikh, FH, 2023) |
| "The rat Langendorff-perfused isolated heart, anaesthetised rat and rat ventricular myocyte preparations were utilised in a series of blinded and randomised studies to investigate the antiarrhythmic effectiveness, adverse effects and mechanism of action of OCT2013, compared with lidocaine." | 1.72 | OCT2013, an ischaemia-activated antiarrhythmic prodrug, devoid of the systemic side effects of lidocaine. ( Chowdhury, RA; Curtis, MJ; Firth, J; Hesketh, LM; MacLeod, KT; Mahoney-Sanchez, L; Mazzacuva, F; Ogrodzinski, S; Patterson, LH; Peters, NS; Sikkel, MB; Tzortzis, KN; Wilder, CDE; Winter, J, 2022) |
| "Ventricular fibrillation was induced in 16 pigs, and circulatory arrest was maintained for 14 minutes." | 1.40 | Effects of potassium/lidocaine-induced cardiac standstill during cardiopulmonary resuscitation in a pig model of prolonged ventricular fibrillation. ( Heo, T; Hun Jung, Y; Il Min, Y; Jeong, IS; Joon Lee, S; Kook Lee, B; Lim, V; Woon Jeung, K; Youn Lee, H, 2014) |
| "Recent guidelines for treating ventricular fibrillation (VF) and ventricular tachycardia (VT) stress class III antiarrhythmic drugs, but some malignant arrhythmias refractory to these agents still occur in clinical practice." | 1.40 | Renewed impact of lidocaine on refractory ventricular arrhythmias in the amiodarone era. ( Ikeda, U; Miura, T; Motoki, H; Okada, A; Takeuchi, T; Tomita, T; Yoshie, K, 2014) |
| "Duration of ventricular tachycardia (VT) episodes was reduced from 15." | 1.37 | First direct comparison of the late sodium current blocker ranolazine to established antiarrhythmic agents in an ischemia/reperfusion model. ( Bhandari, A; Dow, JS; Kloner, RA, 2011) |
| "Hydrofluoric acid (HF) is a weak inorganic acid used for etching and as rust remover." | 1.35 | Recurrent life-threatening ventricular dysrhythmias associated with acute hydrofluoric acid ingestion: observations in one case and implications for mechanism of toxicity. ( Benitez, FL; Delaney, KA; Rivera, W; Velez, LI; Vohra, R, 2008) |
| "Nifekalant hydrochloride(NIF) is a novel class III antiarrhythmic agent for malignant VT/VF." | 1.32 | [Efficacy of Nifekalant hydrochloride for life-threatening ventricular tachyarrhythmias in patients with resistance to lidocaine: a study of patients with out-of-hospital cardiac arrest]. ( Amino, M; Ban, K; Deguchi, Y; Fujikura, H; Goto, S; Handa, S; Inokuchi, S; Iwase, H; Iwata, O; Marutani, Y; Morita, S; Nakagawa, Y; Shiina, Y; Tanabe, T; Yamamoto, I; Yoshioka, K, 2003) |
| "Amiodarone (200 mg/day) was administered for 6 months and programmed ventricular stimulation was repeated." | 1.32 | Intravenous administration of class I antiarrhythmic drug induced T wave alternans in an asymptomatic Brugada syndrome patient. ( Kanmatsuse, K; Kasamaki, Y; Kofune, T; Masaki, R; Ohkubo, K; Okumura, Y; Oshikawa, N; Ozawa, Y; Saito, S; Watanabe, I; Yamada, T, 2003) |
| "Ventricular fibrillation was induced with double extrastimuli applied to the right ventricular outflow tract." | 1.31 | [Brugada syndrome occurring in an identical twin: a case report]. ( Fujiki, A; Inoue, H; Mizumaki, K; Nishida, K; Sakabe, M; Sugao, M; Tsuneda, T, 2002) |
| "Flecainide was equi-effective at low and high concentrations, with VF incidence reduced from 92% to 17% (p < 0." | 1.31 | Limited antifibrillatory effectiveness of clinically relevant concentrations of class I antiarrhythmics in isolated perfused rat hearts. ( Curtis, MJ; Farkas, A, 2002) |
| "When examined on premature beats, AT was delayed, depending on the coupling interval and the fiber direction when saline, flecainide or lidocaine was infused." | 1.30 | Electrophysiologic effects of sodium channel blockade on anisotropic conduction and conduction block in canine myocardium: preferential slowing of longitudinal conduction by flecainide versus disopyramide or lidocaine. ( Kondo, T; Kubota, I; Tachibana, H; Tomoike, H; Yamaki, M, 1997) |
| "h-1) doses of lidocaine on defibrillation energy requirements (DER) to relate changes in indexes of sodium-channel blockade with changes in DER values using a dose-response study design." | 1.30 | High-dose lidocaine does not affect defibrillation efficacy: implications for defibrillation mechanisms. ( Miller, AW; Sims, JJ; Ujhelyi, MR, 1998) |
| "Flecainide 2 mg kg(-1) was administered i." | 1.30 | Effects of lidocaine and mexiletine on defibrillation energy requirements in animals treated with flecainide. ( Imagawa, N; Sato, S, 1998) |
| "Ventricular fibrillation was then electrically induced and maintained in arrest for 5 mins (n = 12) or 15 mins (n = 20)." | 1.29 | Sodium bicarbonate may improve outcome in dogs with brief or prolonged cardiac arrest. ( Bircher, NG; Radovsky, A; Safar, P; Vukmir, RB, 1995) |
| "All patients with prehospital cardiac arrest in Gothenburg reached by mobile coronary care unit or standard ambulance between 1980 and 1992." | 1.29 | Survival after cardiac arrest outside hospital over a 12-year period in Gothenburg. ( Axelsson, A; Bång, A; Ekström, L; Herlitz, J; Holmberg, S; Wennerblom, B, 1994) |
| "Ventricular fibrillation is a complication in patients hospitalized for acute myocardial infarction." | 1.29 | Sixty-six episodes of ventricular fibrillation within four hours: electrical stability restored by propafenone. ( Bellone, P; Spirito, P; Vecchio, C, 1994) |
| " Thus the objective of this investigation was to evaluate the antifibrillatory properties of moricizine (a new antiarrhythmic agent) alone and in combination with lidocaine (an established antifibrillatory agent)." | 1.29 | Antifibrillatory and electrophysiologic actions of moricizine alone and in combination with lidocaine: a prospective, randomized trial. ( Chow, MS; Fan, C; Kluger, J; O'Rangers, EA; Ujhelyi, MR, 1993) |
| "Ventricular fibrillation was induced by endocardial electrical stimulation in pigs anaesthetised with pentobarbitone sodium (30 mg/kg intravenously)." | 1.29 | Effects of blockade of fast and slow inward current channels on ventricular fibrillation in the pig heart. ( Adgey, AA; Allen, JD; Devine, AB; Stewart, AJ, 1996) |
| "Reperfusion arrhythmias (RA) occurred in 19(79." | 1.28 | [Reperfusion arrhythmias in acute myocardial infarction]. ( Gao, R, 1992) |
| "Once ventricular fibrillation was induced, shocks were given 15-20 seconds later via the same electrode configuration to determine the DFT50." | 1.28 | Effects of lidocaine on relation between defibrillation threshold and upper limit of vulnerability in open-chest dogs. ( Cha, YM; Chen, PS; Peters, BB; Topham, SL, 1992) |
| "Ventricular fibrillation was induced using alternating current." | 1.28 | Effects of lidocaine and verapamil on defibrillation in humans. ( Brown, JE; Guiraudon, GM; Jones, DL; Klein, GJ; Sharma, AD; Yee, R, 1991) |
| "Ventricular arrhythmias other than VF are common in acute infarction and, for emotional rather than scientific reasons, often are aggressively treated." | 1.27 | Treatment and prophylaxis of ventricular arrhythmias in acute myocardial infarction. ( Campbell, RW, 1983) |
| "The onset of ventricular arrhythmias was associated with continuous electrical activity in epicardial and intramural electrograms recorded from the reperfused zone." | 1.27 | Ventricular arrhythmias following one-stage and two-stage coronary reperfusion: evidence for both reentry and enhanced automaticity. ( Brachmann, J; Harrison, L; Kabell, G; Lazzara, R; Scherlag, BJ, 1985) |
| "Contemporary approaches to the diagnosis and treatment of acute coronary syndromes have revolutionized the role of the nurse in the coronary care unit." | 1.27 | Nursing management of the patient with acute myocardial infarction. ( Boone, S; Del Negro, AA, 1986) |
| "Mexiletine and tocainide were administered to 79 patients to determine whether the response to one of these drugs would predict the effect of the other." | 1.27 | Mexiletine and tocainide: does response to one predict response to the other? ( Blum, R; Hession, M; Lampert, S; Lown, B; Podrid, PJ; Stein, J, 1986) |
| "Correspondingly, ventricular arrhythmias and fibrillation were almost completely prevented by metoprolol, d-sotalol or verapamil, but increased by lidocaine." | 1.27 | Comparative investigations on the antiarrhythmic and electrophysiologic effects of class I-IV antiarrhythmic agents following acute coronary artery occlusion. ( Gülker, H; Haverkamp, W; Hindricks, G; Thale, J, 1987) |
| "A comparative study of two arrhythmia models was carried out using coronary ligation and reperfusion in anesthetized rats and in isolated rat hearts." | 1.27 | Coronary ligation-reperfusion arrhythmia models in anesthetized rats and isolated perfused rat hearts concentration-effect relationships of lidocaine. ( Follath, F; Ha, HR; Hof, RP; Uematsu, T; Vozeh, S, 1986) |
| "Ventricular fibrillation was preceded by progressive widening of the QRS complexes recorded over the area perfused by the LAD." | 1.27 | Differential depressant and electrophysiologic cardiotoxicity of local anesthetics: an experimental study with special reference to lidocaine and bupivacaine. ( Häggmark, S; Johansson, G; Nath, S; Reiz, S, 1986) |
| "Lidocaine did not inhibit the binding of the lysophospholipid to the red cell membrane, but inhibited hemolysis in a manner similar to cholesterol." | 1.27 | The effect of lidocaine on lysophosphatidylcholine-induced cardiac arrhythmias and cellular disturbances. ( Choy, PC; Lederman, CL; Man, RY; Neufeld, KJ, 1985) |
| " The dose-response effectiveness for the prototype antiarrhythmic drugs, propranolol, quinidine and lidocaine in converting the induced ventricular fibrillation to sinus rhythm was determined." | 1.27 | A cardiac antiarrhythmic screening test using the isolated ischaemic perfused rat heart preparation. ( Lee, AY; Mok, CP; Wong, TM; Zhan, CY, 1985) |
| "Lidocaine was effective in 26 patients and 16 (63%) of these had their arrhythmias controlled with tocainide." | 1.26 | Tocainide for drug-resistant ventricular arrhythmias: efficacy, side effects, and lidocaine responsiveness for predicting tocainide success. ( Harrison, DC; Mason, JW; Winkle, RA, 1980) |
| "Disopyramide has the advantage of being available both as an oral and an intravenous preparation and is a useful drug to be added to the list of more conventional anti-dysrhythmic agents." | 1.26 | Disopyramide--an effective treatment for lignocaine resistant ventricular dysrhythmias. ( Green, AG, 1979) |
| "If properly treated primary ventricular fibrillation is associated with a good short and long term prognosis." | 1.26 | Treatment and prevention of primary ventricular fibrillation complicating acute myocardial infarction. ( Durrer, D; Lie, KI; Liem, KL; Wellens, HJ, 1977) |
| "240 episodes of arrhythmia were observed in 182 of the 502 patients." | 1.26 | [Experiences with a mobile intensive care station (Kardiomobil) after 1 year's test operation in Zurich]. ( Baumann, PC; Frey, P; Kreienbühl, G; Steinbrunn, W, 1976) |
| "Practolol was frequently effective in controlling ventricular dysrhythmias which occurred within the first 24 hours after the onset of symptoms of acute myocardial infarction." | 1.25 | The effects of practolol on the dysrhythmias complicating acute ischemic heart disease. ( Allen, JD; Pantridge, JF; Shanks, RG, 1975) |
| " The total volume of GX distribution in man is similar to that of lidocaine but the plasma clearance is less, so that the 10-hr elimination phase half-life of GX is much longer than the 1 1/2 hr half-life reported in normal subjects for lidocaine." | 1.25 | Pharmacological activity, metabolism, and pharmacokinetics of glycinexylidide. ( Atkinson, AJ; Burris, BC; Mayfield, DE; Raymon, F; Strong, JM; Webster, LT, 1975) |
| "Occlusion of the LAD artery produced arrhythmia in all of the animals, with 39% developing ventricular fibrillation (VF)." | 1.25 | Influence of the adrenal medulla on cardiac rhythm disturbances following acute coronary artery occlusions. ( Kelliher, GJ; Roberts, J; Widmer, C, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 323 (61.17) | 18.7374 |
| 1990's | 88 (16.67) | 18.2507 |
| 2000's | 55 (10.42) | 29.6817 |
| 2010's | 44 (8.33) | 24.3611 |
| 2020's | 18 (3.41) | 2.80 |
| Authors | Studies |
|---|---|
| Banitt, EH | 1 |
| Bronn, WR | 1 |
| Coyne, WE | 1 |
| Schmid, JR | 1 |
| Neumeyer, JL | 1 |
| Perianayagam, C | 1 |
| Ruchirawat, S | 1 |
| Aleksandrowicz, D | 1 |
| Seo, J | 1 |
| Spalla, I | 1 |
| Porteiro Vázquez, DM | 1 |
| Luis Fuentes, V | 1 |
| Tinson, E | 1 |
| Connolly, DJ | 1 |
| Hesketh, LM | 1 |
| Sikkel, MB | 1 |
| Mahoney-Sanchez, L | 1 |
| Mazzacuva, F | 1 |
| Chowdhury, RA | 1 |
| Tzortzis, KN | 1 |
| Firth, J | 1 |
| Winter, J | 1 |
| MacLeod, KT | 1 |
| Ogrodzinski, S | 1 |
| Wilder, CDE | 1 |
| Patterson, LH | 1 |
| Peters, NS | 1 |
| Curtis, MJ | 2 |
| Lane, DJ | 1 |
| Grunau, B | 2 |
| Kudenchuk, P | 1 |
| Dorian, P | 11 |
| Wang, HE | 1 |
| Daya, MR | 1 |
| Lupton, J | 1 |
| Vaillancourt, C | 3 |
| Okubo, M | 1 |
| Davis, D | 1 |
| Rea, T | 4 |
| Yannopoulos, D | 1 |
| Christenson, J | 2 |
| Scheuermeyer, F | 1 |
| Rahimi, M | 1 |
| Cheskes, S | 2 |
| Lebovic, G | 1 |
| Lin, S | 1 |
| Johnson, MC | 1 |
| Wang, L | 1 |
| Wagner, D | 1 |
| Kronick, SL | 1 |
| Nawer, H | 1 |
| Cranford, JA | 1 |
| Bradley, SM | 1 |
| Neumar, RW | 1 |
| Kishihara, Y | 1 |
| Kashiura, M | 1 |
| Amagasa, S | 1 |
| Fukushima, F | 1 |
| Yasuda, H | 1 |
| Moriya, T | 1 |
| Jouffroy, R | 1 |
| Ecollan, P | 1 |
| Chollet-Xemard, C | 1 |
| Prunet, B | 1 |
| Elie, C | 1 |
| Treluyer, JM | 1 |
| Vivien, B | 1 |
| Murphy, TW | 1 |
| Kadir, S | 1 |
| Bracy, CL | 1 |
| Kobres, PY | 1 |
| Hockstein, MJ | 1 |
| Rao, SD | 1 |
| Gupta, R | 1 |
| Lam, PH | 1 |
| Sheikh, FH | 1 |
| Hockstein, MA | 1 |
| Hasebe, H | 1 |
| Yokoya, T | 1 |
| Murakoshi, N | 1 |
| Kurebayashi, N | 1 |
| Tijssen, J | 1 |
| DeCaen, A | 1 |
| Arias, MA | 1 |
| Pachón, M | 1 |
| Loughlin, G | 1 |
| Meyer-Szary, J | 1 |
| Gasecka, A | 1 |
| John, I | 1 |
| Jaguszewski, MJ | 1 |
| Peacock, FW | 1 |
| Gilis-Malinowska, N | 1 |
| Szarpak, L | 1 |
| Taki, M | 1 |
| Muraji, S | 1 |
| Mori, H | 1 |
| Nabeshima, T | 1 |
| Toda, K | 1 |
| Iwamoto, Y | 1 |
| Masutani, S | 1 |
| Kojima, T | 1 |
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| Yusa, T | 1 |
| Sato, T | 1 |
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| Hanazono, N | 1 |
| Herbinger, W | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| aMsa and amiOdarone Study in cArdiaC Arrest[NCT04997980] | 500 participants (Anticipated) | Observational | 2015-01-01 | Recruiting | |||
| Etiology, Incidence and Survival of Pediatric Out-of-hospital Cardiac Arrests: a Four-year Danish Analysis[NCT04275856] | 300 participants (Anticipated) | Observational [Patient Registry] | 2019-02-01 | Active, not recruiting | |||
| Amiodarone, Lidocaine or Neither for Out-Of-Hospital Cardiac Arrest Due to Ventricular Fibrillation (VF) or Ventricular Tachycardia (VT)[NCT01401647] | Phase 3 | 3,024 participants (Actual) | Interventional | 2012-05-31 | Completed | ||
| The Use of Amiodarone vs. Lidocaine and Placebo for the Prevention of Ventricular Fibrillation After Myocardial Reperfusion During Cardiopulmonary Bypass[NCT00587483] | 342 participants (Actual) | Interventional | 2007-11-30 | Completed | |||
| Safety of Local Dental Anesthesia in Patients With Cardiac Channelopathies[NCT03182777] | 31 participants (Actual) | Interventional | 2015-05-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Neurologic status at discharge will be assessed using the modified Rankin Score (MRS). A higher value indicates a worse outcome. 0-No symptoms at all; 1-No significant disability despite symptoms; able to carry out all usual duties and activities, 2-Slight disability; unable to carry out all previous activities, but able to look after own affairs without assistance, 3-Moderate disability; requiring some help, but able to walk without assistance; 4-Moderately severe disability; unable to walk without assistance and unable to attend to own bodily needs without assistance, 5-Severe disability; bedridden, incontinent and requiring constant nursing care and attention; 6-Dead (NCT01401647)
Timeframe: Patients will be followed from the time of the cardiac arrest until death, hospital discharge, or December 31, 2015, whichever occurs first.
| Intervention | Participants (Count of Participants) |
|---|---|
| Amiodarone | 182 |
| Lidocaine | 172 |
| Normal Saline | 175 |
Patients may die in the field (outside of the hospital at the time of the cardiac arrest), at the emergency room, in the hospital, or they are discharged alive from the hospital. (NCT01401647)
Timeframe: Patients will be followed from the time of the cardiac arrest until death, hospital discharge, or December 31, 2015, whichever occurs first.
| Intervention | participants (Number) |
|---|---|
| Amiodarone | 237 |
| Lidocaine | 233 |
| Normal Saline | 222 |
(NCT00587483)
Timeframe: Participants were followed from randomization through the 60 minute period following myocardial reperfusion.
| Intervention | Participants (Number) |
|---|---|
| Lidocaine 1.5 mg /kg | 66 |
| Amiodarone 300 mg | 60 |
| Placebo (Saline) | 70 |
(NCT00587483)
Timeframe: Participants were followed from the date of randomization until the date of discharge from the hospital, assessed up to 60 days.
| Intervention | Days (Mean) |
|---|---|
| Lidocaine 1.5 mg /kg | 6.183 |
| Amiodarone 300 mg | 7.5 |
| Placebo (Saline) | 9.423 |
(NCT00587483)
Timeframe: Participants were followed from the date of randomization until the date of discharge from the Intensive Care Unit, assessed up to 40 days.
| Intervention | Days (Mean) |
|---|---|
| Lidocaine 1.5 mg /kg | 1.357 |
| Amiodarone 300 mg | 5.329 |
| Placebo (Saline) | 4.847 |
Number of participants per arm who experienced arrhythmias while on floor care following dismissal from the ICU. (NCT00587483)
Timeframe: Participants were followed from dismissal from the ICU until dismissal from the hospital.
| Intervention | Participants (Number) | ||
|---|---|---|---|
| Ventricular tachycardia | Atrial fibrillation | Other arrhythmias | |
| Amiodarone 300 mg | 2 | 49 | 42 |
| Lidocaine 1.5 mg /kg | 2 | 56 | 36 |
| Placebo (Saline) | 3 | 38 | 24 |
Number of participants per arm who experienced arrhythmias other than ventricular fibrillation while in the ICU. (NCT00587483)
Timeframe: Participants were followed from randomization through the 60 minute period following myocardial reperfusion.
| Intervention | Participants (Number) | ||
|---|---|---|---|
| Ventricular tachycardia | Atrial fibrillation | Other arrhythmias | |
| Amiodarone 300 mg | 2 | 23 | 35 |
| Lidocaine 1.5 mg /kg | 3 | 21 | 27 |
| Placebo (Saline) | 0 | 18 | 27 |
(NCT00587483)
Timeframe: Participants were followed from randomization through the 60 minute period following myocardial reperfusion.
| Intervention | Participants (Number) | ||
|---|---|---|---|
| 0 Attempts | 1 - 3 Attempts | > 3 Attempts | |
| Amiodarone 300 mg | 57 | 43 | 15 |
| Lidocaine 1.5 mg /kg | 46 | 53 | 16 |
| Placebo (Saline) | 40 | 46 | 14 |
Number of participants per arm who required the use of vasopressors in the post-operative period. (NCT00587483)
Timeframe: Participants were followed from randomization until time to discharge from the hospital.
| Intervention | Participants (Number) | ||
|---|---|---|---|
| Epinephrine | Norepinephrine | Vasopressin | |
| Amiodarone 300 mg | 1 | 0 | 2 |
| Lidocaine 1.5 mg /kg | 1 | 0 | 0 |
| Placebo (Saline) | 0 | 0 | 0 |
52 reviews available for lidocaine and Ventricular Fibrillation
| Article | Year |
|---|---|
Antiarrhythmic drugs for out-of-hospital cardiac arrest with refractory ventricular fibrillation.
Topics: Amiodarone; Anti-Arrhythmia Agents; Emergency Medical Services; Humans; Intensive Care Units; Lidoca | 2017 |
Prophylactic lidocaine for myocardial infarction.
Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Bradycardia; Humans; Lidocaine; Myocardial Infarction; | 2015 |
Amiodarone Versus Lidocaine for Pediatric Cardiac Arrest Due to Ventricular Arrhythmias: A Systematic Review.
Topics: Amiodarone; Anti-Arrhythmia Agents; Child; Combined Modality Therapy; Electric Countershock; Heart A | 2017 |
Should amiodarone or lidocaine be given to patients who arrest after cardiac surgery and fail to cardiovert from ventricular fibrillation?
Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Benchmarking; Cardiac Surgical Procedures; Cardiopulmonary | 2008 |
[Brugada syndrome, bupivacaine, lidocaine, and techniques to provide local or regional anesthesia: comments on "Ventricular fibrillation in a patient with a type I Brugada syndrome ECG pattern and hypokalemia"].
Topics: Anesthesia, Conduction; Anesthetics, Local; Brugada Syndrome; Bupivacaine; Female; Humans; Hypokalem | 2008 |
Ventricular tachyarrhythmias (out-of-hospital cardiac arrests).
Topics: Amiodarone; Death, Sudden, Cardiac; Electric Countershock; Humans; Hypothermia, Induced; Lidocaine; | 2010 |
Strategies for reversing shock-resistant ventricular fibrillation.
Topics: Adrenergic beta-Antagonists; Amiodarone; Anti-Arrhythmia Agents; Bretylium Compounds; Cardiopulmonar | 2003 |
Cardiopulmonary Resuscitation Guidelines 2000 update: what's happened since?
Topics: Amiodarone; Anti-Arrhythmia Agents; Cardiopulmonary Resuscitation; Electric Countershock; Emergency | 2003 |
Prophylactic lidocaine in acute myocardial infarction: resurface or reburial?
Topics: Anti-Arrhythmia Agents; Chemoprevention; Humans; Incidence; Lidocaine; Myocardial Infarction; Ventri | 2004 |
Pediatric cardiopulmonary resuscitation.
Topics: Adolescent; Airway Obstruction; Aminophylline; Atropine; Bicarbonates; Blood Circulation; Bretylium | 1983 |
Prophylactic antiarrhythmic therapy in acute myocardial infarction.
Topics: Adrenergic beta-Antagonists; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Hospitalization; Humans; | 1984 |
Should prophylactic antiarrhythmic drug therapy be employed in acute myocardial infarction?
Topics: Aged; Anti-Arrhythmia Agents; Clinical Trials as Topic; Humans; Kinetics; Lidocaine; Myocardial Infa | 1983 |
Prophylaxis and therapy of ventricular fibrillation: bretylium reviewed and lidocaine refuted.
Topics: Animals; Anti-Arrhythmia Agents; Bethanidine; Bretylium Compounds; Bretylium Tosylate; Electrocardio | 1983 |
Arrhythmias in acute myocardial infarction.
Topics: Arrhythmias, Cardiac; Bradycardia; Heart Block; Humans; Lidocaine; Myocardial Infarction; Pacemaker, | 1984 |
Comparison of the efficacy of newly developed antiarrhythmic drugs in the treatment of ventricular tachyarrhythmias.
Topics: Anilides; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Benzeneacetamides; Coronary Disease; Encaini | 1984 |
Antiarrhythmic prophylaxis after acute myocardial infarction. Is lidocaine still useful?
Topics: Humans; Lidocaine; Myocardial Infarction; Ventricular Fibrillation | 1993 |
Prolonged QT syndrome: perioperative management.
Topics: Adolescent; Adult; Atropine; Carcinoma, Squamous Cell; Child; Female; Glossectomy; Heart Arrest; Hum | 1993 |
An overview of antiarrhythmic drug management of electrical storm.
Topics: Amiodarone; Anti-Arrhythmia Agents; Clinical Trials as Topic; Humans; Infusions, Intravenous; Lidoca | 1996 |
Antiarrhythmic drugs in resuscitation.
Topics: Anti-Arrhythmia Agents; Combined Modality Therapy; Electric Countershock; Emergency Treatment; Human | 1998 |
Management of ventricular arrhythmias: detection, drugs, and devices.
Topics: Algorithms; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cardiac Surgical Procedures; Cardiovascula | 1999 |
Prophylactic lidocaine use in acute myocardial infarction revisited in the thrombolytic era.
Topics: Animals; Anti-Arrhythmia Agents; Drug Therapy, Combination; Fibrinolytic Agents; Humans; Lidocaine; | 1999 |
Cardiac arrhythmias in the dog: detection and treatment.
Topics: Animals; Arrhythmia, Sinus; Arrhythmias, Cardiac; Atrial Fibrillation; Bradycardia; Cardiac Complexe | 1976 |
[Significance and therapy of extrasystole].
Topics: Aprindine; Arrhythmias, Cardiac; Cardiac Complexes, Premature; Cardiac Output; Heart Ventricles; Hum | 1977 |
The management of acute coronary insufficiency.
Topics: Acute Disease; Angina Pectoris; Animals; Anti-Arrhythmia Agents; Arteriosclerosis; Aspartate Aminotr | 1977 |
Recognition and treatment of cardiac emergencies.
Topics: Acidosis; Animals; Bicarbonates; Calcium; Dog Diseases; Dogs; Electric Countershock; Electrocardiogr | 1977 |
[Prognostic significance of arrhythmias in acute myocardial infarction (author's transl)].
Topics: Acute Disease; Arrhythmias, Cardiac; Coronary Care Units; Electrocardiography; Humans; Lidocaine; My | 1977 |
Should lidocaine be administered routinely to all patients after acute myocardial infarction?
Topics: Acute Disease; Age Factors; Arrhythmias, Cardiac; Coronary Care Units; Critical Care; Electrocardiog | 1978 |
Lidocaine prophylaxis in acute myocardial infarction.
Topics: Acute Disease; Double-Blind Method; Heart Rate; Humans; Lidocaine; Myocardial Infarction; Risk; Time | 1978 |
Acute myocardial infarction.
Topics: Animals; Aspartate Aminotransferases; Atropine; Clinical Enzyme Tests; Creatine Kinase; Dogs; Electr | 1979 |
Lignocaine and bretylium as adjuncts to electrical defibrillation.
Topics: Animals; Anti-Arrhythmia Agents; Bretylium Compounds; Cardiopulmonary Resuscitation; Electric Counte | 1991 |
Treatment and prevention of ventricular fibrillation: are there better agents?
Topics: Adrenergic beta-Antagonists; Animals; Anti-Arrhythmia Agents; Bretylium Compounds; Cardiopulmonary R | 1991 |
Lidocaine prophylaxis in acute myocardial infarction.
Topics: Humans; Lidocaine; Myocardial Infarction; Ventricular Fibrillation | 1991 |
Reconsiderations of the routine and preferential use of lidocaine in the emergent treatment of ventricular arrhythmias.
Topics: Arrhythmias, Cardiac; Combined Modality Therapy; Electric Countershock; Emergencies; Humans; Lidocai | 1991 |
Lidocaine in the early phase of acute myocardial infarction: the controversy over prophylactic or selective use.
Topics: Acute Disease; Arrhythmias, Cardiac; Humans; Lidocaine; Myocardial Infarction; Time Factors; Ventric | 1990 |
The treatment of ventricular rhythm disturbances.
Topics: Adrenergic beta-Antagonists; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cardiac Complexes, Premat | 1986 |
Effects of prophylactic lidocaine in suspected acute myocardial infarction. An overview of results from the randomized, controlled trials.
Topics: Clinical Trials as Topic; Double-Blind Method; Humans; Injections, Intravenous; Lidocaine; Myocardia | 1988 |
Modification of the electrophysiologic matrix by antiarrhythmic drugs.
Topics: Action Potentials; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Benzocaine; Electrophysiology; Hear | 1985 |
Supraventricular and ventricular dysrhythmias in infants and children.
Topics: Arrhythmias, Cardiac; Bradycardia; Cardiac Complexes, Premature; Child; Child, Preschool; Deafness; | 1972 |
[Anti-arrhythmia agents].
Topics: Action Potentials; Ajmaline; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Fibrillation; Atri | 1974 |
[Treatment of arrhythmia at coronary care units].
Topics: Adult; Aged; Ajmaline; Animals; Arrhythmias, Cardiac; Atropine; Bretylium Compounds; Cardiac Complex | 1974 |
Treatment of cardiac arrhythmias.
Topics: Adams-Stokes Syndrome; Arrhythmia, Sinus; Arrhythmias, Cardiac; Atrial Fibrillation; Atrial Flutter; | 1964 |
Current status of antiarrhythmic drug therapy.
Topics: Anesthetics, Local; Anti-Arrhythmia Agents; Anticonvulsants; Antimalarials; Arrhythmias, Cardiac; At | 1968 |
Cardiac arrhythmias. 6. Present status of electroversion in the management of cardiac dysrhythmias.
Topics: Anticoagulants; Arrhythmias, Cardiac; Atrial Flutter; Cardiomegaly; Digitalis Glycosides; Electric C | 1973 |
[Arrhythmia. 2. Treatment of arrhythmias in a coronary care unit].
Topics: Adrenergic beta-Antagonists; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atropine; Coronary Care U | 1971 |
Life-threatening arrhythmias.
Topics: Adult; Aged; Angina Pectoris; Arrhythmias, Cardiac; Bradycardia; Electrocardiography; Female; Heart | 1973 |
The prophylactic use of anti-arrhythmic drugs in acute myocardial infarction.
Topics: Acute Disease; Aged; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atropine; Bradycardia; Death, Sud | 1973 |
Antiarrhythmic actions of lidocaine.
Topics: Action Potentials; Animals; Cell Membrane; Central Nervous System Diseases; Digitalis; Drug Interact | 1974 |
Reevaluating the use of lidocaine.
Topics: Adult; Animals; Arrhythmias, Cardiac; Cats; Central Nervous System; Depression, Chemical; Dogs; Elec | 1973 |
Editorial: Primary ventricular fibrillation.
Topics: Animals; Dogs; Heart Rate; Humans; Intensive Care Units; Lidocaine; Myocardial Infarction; Procainam | 1974 |
Changing concepts in the care of patients with acute myocardial infarction.
Topics: Arrhythmias, Cardiac; Atrial Fibrillation; Blood Gas Analysis; Bundle-Branch Block; Cardiac Output; | 1969 |
New look at arrhythmias.
Topics: Adams-Stokes Syndrome; Arrhythmias, Cardiac; Diagnosis, Differential; Electric Countershock; Electro | 1969 |
Prevention and treatment of ventricular dysrhythmias.
Topics: Arrhythmias, Cardiac; Atropine; Coronary Care Units; Electric Countershock; Heart Block; Humans; Iso | 1971 |
59 trials available for lidocaine and Ventricular Fibrillation
| Article | Year |
|---|---|
Effect of Time to Treatment With Antiarrhythmic Drugs on Return of Spontaneous Circulation in Shock-Refractory Out-of-Hospital Cardiac Arrest.
Topics: Adult; Amiodarone; Anti-Arrhythmia Agents; Cardiopulmonary Resuscitation; Humans; Lidocaine; Out-of- | 2022 |
Effects of intra-resuscitation antiarrhythmic administration on rearrest occurrence and intra-resuscitation ECG characteristics in the ROC ALPS trial.
Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Canada; Cardiopulmonary Resuscitation; Electrocardiography | 2018 |
Resuscitation Outcomes Consortium-Amiodarone, Lidocaine or Placebo Study (ROC-ALPS): Rationale and methodology behind an out-of-hospital cardiac arrest antiarrhythmic drug trial.
Topics: Adolescent; Adult; Amiodarone; Anti-Arrhythmia Agents; Cardiopulmonary Resuscitation; Dose-Response | 2014 |
The effect of lidocaine and amiodarone on prevention of ventricular fibrillation in patients undergoing coronary artery bypass grafting.
Topics: Amiodarone; Anti-Arrhythmia Agents; Coronary Artery Bypass; Double-Blind Method; Drug Therapy, Combi | 2014 |
Amiodarone, Lidocaine, or Placebo in Out-of-Hospital Cardiac Arrest.
Topics: Adult; Aged; Amiodarone; Anti-Arrhythmia Agents; Cardiopulmonary Resuscitation; Central Nervous Syst | 2016 |
Effects of intravenous nifekalant as a lifesaving drug for severe ventricular tachyarrhythmias complicating acute coronary syndrome.
Topics: Acute Coronary Syndrome; Aged; Amiodarone; Anti-Arrhythmia Agents; Blood Pressure; Electrocardiograp | 2009 |
Prophylactic amiodarone versus lidocaine for prevention of reperfusion ventricular fibrillation after release of aortic cross-clamp.
Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Clinical Protocols; Coronary Artery Bypass; Female; Humans | 2009 |
Amiodarone versus lidocaine and placebo for the prevention of ventricular fibrillation after aortic crossclamping: a randomized, double-blind, placebo-controlled trial.
Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Aorta; Cardiac Surgical Procedures; Chi-Square Distributio | 2012 |
Shock on T versus direct current voltage for induction of ventricular fibrillation: a randomized prospective comparison.
Topics: Amiodarone; Defibrillators, Implantable; Digoxin; Electric Countershock; Female; Humans; Lidocaine; | 2004 |
Randomized double-blind trial of sotalol versus lignocaine in out-of-hospital refractory cardiac arrest due to ventricular tachyarrhythmia.
Topics: Aged; Anti-Arrhythmia Agents; Female; Follow-Up Studies; Heart Arrest; Humans; Lidocaine; Male; Outp | 2005 |
Clinical significance of macroscopic T-wave alternans after sodium channel blocker administration in patients with Brugada syndrome.
Topics: Brugada Syndrome; Electrocardiography; Female; Humans; Lidocaine; Male; Middle Aged; Sodium Channel | 2008 |
Lignocaine prophylaxis in acute myocardial infarction: an evaluation of randomised trials.
Topics: Clinical Trials as Topic; Evaluation Studies as Topic; Humans; Lidocaine; Myocardial Infarction; Ran | 1981 |
[Prevention of ventricular fibrillation using lidocaine in the acute period of a myocardial infarct].
Topics: Cardiac Complexes, Premature; Critical Care; Drug Evaluation; Drug Therapy, Combination; Electrocard | 1982 |
Should prophylactic antiarrhythmic drug therapy be employed in acute myocardial infarction?
Topics: Aged; Anti-Arrhythmia Agents; Clinical Trials as Topic; Humans; Kinetics; Lidocaine; Myocardial Infa | 1983 |
Relationship between infarct size and incidence of severe ventricular arrhythmias in a double-blind trial with metoprolol in acute myocardial infarction.
Topics: Adult; Aged; Clinical Trials as Topic; Double-Blind Method; Female; Humans; L-Lactate Dehydrogenase; | 1984 |
Prophylaxis of primary ventricular fibrillation in acute myocardial infarction. The case against lignocaine.
Topics: Anti-Arrhythmia Agents; Clinical Trials as Topic; Coronary Care Units; Humans; Lidocaine; Myocardial | 1984 |
A randomized comparison study of bretylium tosylate and lidocaine in resuscitation of patients from out-of-hospital ventricular fibrillation in a paramedic system.
Topics: Aged; Allied Health Personnel; Bretylium Compounds; Bretylium Tosylate; Clinical Trials as Topic; Fe | 1984 |
Prophylaxis of primary ventricular fibrillation with tocainide in acute myocardial infarction.
Topics: Anti-Arrhythmia Agents; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Lidocaine; Ma | 1983 |
Prophylaxis against ventricular arrhythmias in suspected acute myocardial infarction: a comparison of tocainide and disopyramide.
Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Disopyramide; Female; Humans; Lidocaine; Male; Middle | 1984 |
Comparison of bretylium tosylate and lidocaine in management of out of hospital ventricular fibrillation: a randomized clinical trial.
Topics: Bretylium Compounds; Bretylium Tosylate; Clinical Trials as Topic; Double-Blind Method; Electric Cou | 1981 |
Lidocaine: antiarrhythmic panacea or cardiac cosmetic agent.
Topics: Clinical Trials as Topic; Double-Blind Method; Humans; Lidocaine; Myocardial Infarction; Random Allo | 1981 |
Lidocaine prophylaxis for fatal ventricular arrhythmias after acute myocardial infarction.
Topics: Aged; Double-Blind Method; Female; Heart Failure; Hospital Mortality; Humans; Infusions, Intravenous | 1995 |
Incidence of ventricular fibrillation after aortic cross-clamp release using lignocaine cardioplegia.
Topics: Adult; Aged; Aged, 80 and over; Aorta; Cardiac Pacing, Artificial; Cardioplegic Solutions; Cardiopul | 1994 |
"Helper:" A critical events prompter for unexpected emergencies.
Topics: Algorithms; Anesthesia, General; Anesthesiology; Anti-Arrhythmia Agents; Bradycardia; Clinical Proto | 1995 |
Relationship between QT dispersion and the incidence of early ventricular arrhythmias in patients with acute myocardial infarction.
Topics: Aged; Chi-Square Distribution; Creatine Kinase; Electric Countershock; Electrocardiography; Electrol | 1997 |
Incidence and prognosis of early primary ventricular fibrillation in acute myocardial infarction--results of the Gruppo Italiano per lo Studio della Sopravvivenza nell'Infarto Miocardico (GISSI-2) database.
Topics: Anti-Arrhythmia Agents; Anticoagulants; Aspirin; Atenolol; Drug Administration Routes; Electrocardio | 1998 |
Prophylactic lidocaine use in acute myocardial infarction: incidence and outcomes from two international trials. The GUSTO-I and GUSTO-IIb Investigators.
Topics: Aged; Anti-Arrhythmia Agents; Drug Therapy, Combination; Female; Fibrinolytic Agents; Follow-Up Stud | 1999 |
Lidocaine for prevention of reperfusion ventricular fibrillation after release of aortic cross-clamping.
Topics: Adult; Aged; Anti-Arrhythmia Agents; Coronary Artery Bypass; Female; Hemodynamics; Humans; Lidocaine | 2000 |
Amiodarone as compared with lidocaine for shock-resistant ventricular fibrillation.
Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Combined Modality Therapy; Double-Blind Method; Electric C | 2002 |
Anti-dysrhythmic treatment in acute myocardial infarction.
Topics: Acute Disease; Administration, Oral; Atenolol; Clinical Trials as Topic; Disopyramide; Double-Blind | 1979 |
Efficacy of lidocaine in preventing primary ventricular fibrillation within 1 hour after a 300 mg intramuscular injection. A double-blind, randomized study of 300 hospitalized patients with acute myocardial infarction.
Topics: Adult; Clinical Trials as Topic; Double-Blind Method; Drug Evaluation; Female; Humans; Injections, I | 1978 |
Lidocaine prophylaxis in acute myocardial infarction.
Topics: Acute Disease; Double-Blind Method; Heart Rate; Humans; Lidocaine; Myocardial Infarction; Risk; Time | 1978 |
[Lidocaine prophylaxis in the pre-hospital phase of acute myocardial infarction (author's transl)].
Topics: Adult; Aged; Clinical Trials as Topic; Double-Blind Method; Hospitalization; Humans; Lidocaine; Midd | 1979 |
Editorial: Lidocaine: prophylactic value in myocardial infarction.
Topics: Acute Disease; Adult; Clinical Trials as Topic; Female; Humans; Injections, Intramuscular; Injection | 1975 |
Effects of the quaternary ammonium compound OX-572 on ventricular tachyarrhythmias complicating acute myocardial infarction.
Topics: Adult; Aged; Blood Pressure; Carbamates; Electrocardiography; Female; Heart Rate; Heart Ventricles; | 1975 |
Lidocaine to prevent ventricular fibrillation in the prehospital phase of suspected acute myocardial infarction: the North-Norwegian Lidocaine Intervention Trial.
Topics: Adult; Aged; Emergency Medical Services; Female; Heart Arrest; Humans; Lidocaine; Male; Middle Aged; | 1992 |
Life-threatening arrhythmias after intravenous lidocaine alone or with magnesium in myocardial infarction complicated by ventricular fibrillation.
Topics: Aged; Aged, 80 and over; Arrhythmias, Cardiac; Drug Therapy, Combination; Female; Humans; Injections | 1991 |
Comparison of bretylium and lidocaine in the prevention of ventricular fibrillation after aortic cross-clamp release in coronary artery bypass surgery.
Topics: Aged; Bretylium Compounds; Constriction; Double-Blind Method; Female; Humans; Lidocaine; Male; Middl | 1990 |
Effect of epinephrine and lidocaine therapy on outcome after cardiac arrest due to ventricular fibrillation.
Topics: Bicarbonates; Electric Countershock; Electrocardiography; Epinephrine; Evaluation Studies as Topic; | 1990 |
Incidence and prognosis of secondary ventricular fibrillation in acute myocardial infarction. Evidence for a protective effect of thrombolytic therapy. GISSI Investigators.
Topics: Aged; Cause of Death; Coronary Care Units; Female; Fibrinolytic Agents; Follow-Up Studies; Hospitali | 1990 |
Prophylactic lidocaine in the prehospital patient with chest pain of suspected cardiac origin.
Topics: Adult; Age Factors; Aged; Angina, Unstable; Arrhythmias, Cardiac; Blood Pressure; Cardiac Complexes, | 1986 |
Effects of prophylactic lidocaine in suspected acute myocardial infarction. An overview of results from the randomized, controlled trials.
Topics: Clinical Trials as Topic; Double-Blind Method; Humans; Injections, Intravenous; Lidocaine; Myocardia | 1988 |
[Ineffective use of lidocaine in preventing reperfusion arrhythmias in patients with acute myocardial infarct].
Topics: Angioplasty, Balloon; Arrhythmias, Cardiac; Combined Modality Therapy; Coronary Circulation; Electro | 1985 |
[Effectiveness of lidocaine in the prevention of primary ventricular fibrillation in acute myocardial infarction. Multiple initial intravenous doses of the drug].
Topics: Adult; Aged; Clinical Trials as Topic; Female; Humans; Infusions, Intravenous; Injections, Intraveno | 1987 |
Lidocaine enhances intraoperative ventricular defibrillation.
Topics: Catecholamines; Coronary Artery Bypass; Dose-Response Relationship, Drug; Electric Countershock; Hum | 1986 |
Prevention of ventricular fibrillation after myocardial revascularization.
Topics: Aorta; Constriction; Coronary Artery Bypass; Humans; Lidocaine; Prospective Studies; Random Allocati | 1987 |
Lidocaine to prevent ventricular fibrillation in early acute myocardial infarction.
Topics: Clinical Trials as Topic; Humans; Lidocaine; Myocardial Infarction; Research Design; Ventricular Fib | 1986 |
Prophylactic lidocaine in the early phase of suspected myocardial infarction.
Topics: Adult; Aged; Arrhythmias, Cardiac; Brain Diseases; Cardiovascular Diseases; Clinical Trials as Topic | 1985 |
Intramuscular lidocaine for prevention of lethal arrhythmias in the prehospitalization phase of acute myocardial infarction.
Topics: Aged; Clinical Trials as Topic; Electrocardiography; Emergency Medical Services; Female; Humans; Inj | 1985 |
Lidocaine to prevent ventricular fibrillation: easy does it.
Topics: Clinical Trials as Topic; Emergency Medical Services; Humans; Injections, Intramuscular; Lidocaine; | 1985 |
Trial of combined intramuscular and intravenous lignocaine in prophylaxis of ventricular tachyarrhythmias.
Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Electrocardiography; Female; Humans; Injections, Intra | 1972 |
Mexiletine (Kö 1173) in the management of ventricular dysrhythmias.
Topics: Administration, Oral; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Bradycardia; Cardiac Complexes, | 1973 |
[Ventricular tachycardia and "volley of ventricular spikes". Morphological frontiers between ventricular dysrhythmias].
Topics: Cardiac Complexes, Premature; Clinical Trials as Topic; Diagnosis, Differential; Electrocardiography | 1973 |
[Anti-arrhythmic efficacy of aprindine during the acute phase of myocardial infarct].
Topics: Administration, Oral; Aniline Compounds; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cardiac Compl | 1974 |
[Ventricular fibrillation at the acute phase of myocardial infarction: prognosis after resuscitation].
Topics: Adult; Ajmaline; Angina Pectoris; Clinical Trials as Topic; Diagnosis, Differential; Electric Counte | 1973 |
Controlled trial of prophylatic treatment with lidocaine in acute myocardial infarction.
Topics: Adult; Aged; Blood Pressure; Bradycardia; Clinical Trials as Topic; Depression, Chemical; Electrocar | 1973 |
Prophylactic lignocaine in hospitalized patients with acute myocardial infarction.
Topics: Acute Disease; Arrhythmias, Cardiac; Clinical Trials as Topic; Humans; Lidocaine; Myocardial Infarct | 1973 |
Lidocaine in the prevention of primary ventricular fibrillation. A double-blind, randomized study of 212 consecutive patients.
Topics: Arrhythmias, Cardiac; Clinical Trials as Topic; Drug Evaluation; Female; Humans; Injections, Intrave | 1974 |
Lignocaine therapy for ventricular ectopic activity after acute myocardial infarction: a double-blind trial.
Topics: Acute Disease; Adult; Aged; Arrhythmias, Cardiac; Blood Gas Analysis; Clinical Trials as Topic; Elec | 1971 |
420 other studies available for lidocaine and Ventricular Fibrillation
| Article | Year |
|---|---|
Antiarrhythmics. 2. Synthesis and antiarrhythmic activity of N-(piperidylalkyl)trifluoroethoxybenzamides.
Topics: Animals; Anti-Arrhythmia Agents; Benzamides; Chloroform; Female; Mice; Structure-Activity Relationsh | 1977 |
Isoquinolines. 5. Synthesis and antiarrhythmic activity of benzylisoquinoline derivatives.
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Chloroform; Dogs; Female; Isoquinolines; Mice | 1977 |
Amiodarone or lidocaine, that is the question - Pharmacological therapy of refractory ventricular fibrillation associated with Brugada syndrome.
Topics: Amiodarone; Anti-Arrhythmia Agents; Brugada Syndrome; Humans; Lidocaine; Ventricular Fibrillation | 2021 |
Rhythm disturbances associated with lidocaine administration in four dogs with supraventricular tachyarrhythmias.
Topics: Animals; Atrial Fibrillation; Dog Diseases; Dogs; Electric Countershock; Lidocaine; Tachycardia; Ven | 2022 |
OCT2013, an ischaemia-activated antiarrhythmic prodrug, devoid of the systemic side effects of lidocaine.
Topics: Animals; Anti-Arrhythmia Agents; Ischemia; Lidocaine; Myocardial Ischemia; Prodrugs; Rats; Rats, Wis | 2022 |
Bayesian analysis of amiodarone or lidocaine versus placebo for out-of-hospital cardiac arrest.
Topics: Adult; Amiodarone; Anti-Arrhythmia Agents; Bayes Theorem; Humans; Lidocaine; Out-of-Hospital Cardiac | 2022 |
The imperfect storm: An uncommon presentation of Chagas disease.
Topics: Arrhythmias, Cardiac; Chagas Disease; Defibrillators, Implantable; Humans; Lidocaine; Tachycardia, V | 2022 |
Comparative Effectiveness of Amiodarone and Lidocaine for the Treatment of In-Hospital Cardiac Arrest.
Topics: Adult; Amiodarone; Anti-Arrhythmia Agents; Cardiopulmonary Resuscitation; Hospitals; Humans; Lidocai | 2023 |
Comparison of the effects of lidocaine and amiodarone for out-of-hospital cardiac arrest patients with shockable rhythms: a retrospective observational study from a multicenter registry.
Topics: Adult; Amiodarone; Cardiopulmonary Resuscitation; Electric Countershock; Emergency Medical Services; | 2022 |
Evaluation of the effectiveness of potassium chloride in the management of out-of hospital cardiac arrest by refractory ventricular fibrillation: Study protocol of the POTACREH study.
Topics: Amiodarone; Cardiopulmonary Resuscitation; Clinical Trials, Phase II as Topic; Electric Countershock | 2023 |
Regarding the Comparative Effectiveness of Lidocaine and Amiodarone for Treatment of In-Hospital Cardiac Arrest.
Topics: Amiodarone; Anti-Arrhythmia Agents; Cardiopulmonary Resuscitation; Heart Arrest; Hospitals; Humans; | 2023 |
Stable Ventricular Fibrillation: A Paradigm Rather Than Septal Shift?
Topics: Amiodarone; Arrhythmias, Cardiac; Humans; Lidocaine; Tachycardia, Ventricular; Ventricular Fibrillat | 2023 |
Pilsicainide Administration Unmasks a Phenotype of Brugada Syndrome in a Patient with Overlap Syndrome due to the E1784K SCN5A Mutation.
Topics: Adult; Anti-Arrhythmia Agents; Brugada Syndrome; Electrocardiography; Humans; Lidocaine; Long QT Syn | 2020 |
No shocking updates for the lidocaine vs amiodarone in pediatric pVT/VF story.
Topics: Amiodarone; Anti-Arrhythmia Agents; Child; Humans; Lidocaine; Ventricular Fibrillation | 2020 |
New Onset Recurrent Syncope Triggered by Fever.
Topics: Amiodarone; Coronary Angiography; Drug Therapy, Combination; Electric Countershock; Electrocardiogra | 2020 |
Outcomes associated with lidocaine and amiodarone administration in pediatric in-hospital cardiac arrest.
Topics: Amiodarone; Anti-Arrhythmia Agents; Child; Heart Arrest; Hospitals; Humans; Lidocaine; Ventricular F | 2021 |
Efficacy of a Subcutaneous Implantable Cardioverter Defibrillator in a Child with Early Repolarization Syndrome.
Topics: Anti-Arrhythmia Agents; Child; Death, Sudden, Cardiac; Defibrillators, Implantable; Electrocardiogra | 2021 |
Time to amiodarone administration and survival outcomes in refractory ventricular fibrillation.
Topics: Adult; Amiodarone; Anti-Arrhythmia Agents; Cardiopulmonary Resuscitation; Emergency Medical Services | 2021 |
Utility of 12-lead and signal-averaged Holter electrocardiograms after pilsicainide provocation for risk stratification in Brugada syndrome.
Topics: Anti-Arrhythmia Agents; Brugada Syndrome; Electrocardiography, Ambulatory; Female; Humans; Lidocaine | 2017 |
Prognostic Significance of the Sodium Channel Blocker Test in Patients With Brugada Syndrome.
Topics: Administration, Intravenous; Adult; Aged; Brugada Syndrome; Death, Sudden, Cardiac; Electrocardiogra | 2018 |
A novel approach to devise the therapy for ventricular fibrillation by epicardial delivery of lidocaine using active hydraulic ventricular attaching support system: An experimental study in rats.
Topics: Animals; Dose-Response Relationship, Drug; Drug Carriers; Drug Liberation; Electrocardiography; Hear | 2019 |
2018 American Heart Association Focused Update on Advanced Cardiovascular Life Support Use of Antiarrhythmic Drugs During and Immediately After Cardiac Arrest: An Update to the American Heart Association Guidelines for Cardiopulmonary Resuscitation and Em
Topics: American Heart Association; Amiodarone; Anti-Arrhythmia Agents; Cardiopulmonary Resuscitation; Emerg | 2018 |
2018 American Heart Association Focused Update on Pediatric Advanced Life Support: An Update to the American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care.
Topics: American Heart Association; Amiodarone; Anti-Arrhythmia Agents; Cardiopulmonary Resuscitation; Child | 2018 |
Clinical and Electrocardiographic Differences in Brugada Syndrome With Spontaneous or Drug-Induced Type 1 Electrocardiogram.
Topics: Adult; Anti-Arrhythmia Agents; Brugada Syndrome; Electrocardiography; Female; Humans; Lidocaine; Mal | 2019 |
Outcomes associated with amiodarone and lidocaine for the treatment of adult in-hospital cardiac arrest with shock-refractory pulseless ventricular tachyarrhythmia.
Topics: Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Electric Countershock; Female; Heart Ar | 2020 |
Administration of amiodarone during resuscitation is associated with higher tumor necrosis factor-α levels in the early postarrest period in the swine model of ischemic ventricular fibrillation.
Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Cardiopulmonary Resuscitation; Coronary Vessels; Diseas | 2013 |
Prophylactic lidocaine for post resuscitation care of patients with out-of-hospital ventricular fibrillation cardiac arrest.
Topics: Aged; Anti-Arrhythmia Agents; Cardiopulmonary Resuscitation; Emergency Medical Services; Female; Hum | 2013 |
Prophylactic amiodarone and lidocaine improve survival in an ovine model of large size myocardial infarction.
Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Fibrillation; Disease Mode | 2013 |
Outcomes associated with amiodarone and lidocaine in the treatment of in-hospital pediatric cardiac arrest with pulseless ventricular tachycardia or ventricular fibrillation.
Topics: Adolescent; Amiodarone; Anti-Arrhythmia Agents; Child; Child, Preschool; Cohort Studies; Heart Arres | 2014 |
A rare loss-of-function SCN5A variant is associated with lidocaine-induced ventricular fibrillation.
Topics: Anesthetics, Local; Female; HEK293 Cells; Humans; Lidocaine; Middle Aged; NAV1.5 Voltage-Gated Sodiu | 2014 |
Effects of potassium/lidocaine-induced cardiac standstill during cardiopulmonary resuscitation in a pig model of prolonged ventricular fibrillation.
Topics: Animals; Biomarkers; Cardioplegic Solutions; Cardiopulmonary Resuscitation; Disease Models, Animal; | 2014 |
Renewed impact of lidocaine on refractory ventricular arrhythmias in the amiodarone era.
Topics: Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Drug Therapy, Combination; Female; Huma | 2014 |
Idiopathic ventricular fibrillation associated with early repolarization which was unmasked by a sodium channel blocker after catheter ablation of atrial fibrillation.
Topics: Atrial Fibrillation; Catheter Ablation; Electrocardiography; Female; Follow-Up Studies; Humans; Inje | 2014 |
Letter to the editor regarding manuscript "resuscitation outcomes consortium-amiodarone, lidocaine or placebo: rationale and methodology behind out-of-hospital cardiac arrest antiarrhythmic drug trial".
Topics: Amiodarone; Cardiopulmonary Resuscitation; Female; Humans; Lidocaine; Male; Out-of-Hospital Cardiac | 2014 |
Regarding manuscript: "resuscitation outcomes consortium-amiodarone, lidocaine, or placebo study: rationale and methodology behind out-of-hospital cardiac arrest antiarrhythmic drug trial".
Topics: Amiodarone; Cardiopulmonary Resuscitation; Female; Humans; Lidocaine; Male; Out-of-Hospital Cardiac | 2014 |
The evaluation of biochemical effects of potassium/lidocaine-induced cardiac standstill application on troponin-I levels in a pig model.
Topics: Animals; Cardioplegic Solutions; Cardiopulmonary Resuscitation; Heart Arrest; Lidocaine; Male; Potas | 2014 |
Significance of electrocardiogram recording in high intercostal spaces in patients with early repolarization syndrome.
Topics: Adult; Anti-Arrhythmia Agents; Brugada Syndrome; Electrocardiography; Electrophysiologic Techniques, | 2016 |
Investigation of the antifibrillatory drug interactions between Amiodarone and Ibutilide in isolated, perfused Rabbit hearts.
Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Drug Interactions; Heart; Lidocai | 2015 |
Amiodarone, Lidocaine, or Placebo in Out-of-Hospital Cardiac Arrest.
Topics: Amiodarone; Anti-Arrhythmia Agents; Cardiopulmonary Resuscitation; Emergency Medical Services; Heart | 2016 |
Amiodarone, Lidocaine, or Placebo in Out-of-Hospital Cardiac Arrest.
Topics: Amiodarone; Anti-Arrhythmia Agents; Cardiopulmonary Resuscitation; Emergency Medical Services; Heart | 2016 |
Amiodarone, Lidocaine, or Placebo in Out-of-Hospital Cardiac Arrest.
Topics: Amiodarone; Anti-Arrhythmia Agents; Cardiopulmonary Resuscitation; Emergency Medical Services; Heart | 2016 |
Amiodarone Compared with Lidocaine for Out-Of-Hospital Cardiac Arrest with Refractory Ventricular Fibrillation on Hospital Arrival: a Nationwide Database Study.
Topics: Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Databases, Factual; Female; Hospital Mo | 2016 |
In Patients With Cardiac Arrest, Does Amiodarone or Lidocaine Increase Meaningful Survival?
Topics: Amiodarone; Anti-Arrhythmia Agents; Heart Arrest; Humans; Lidocaine; Ventricular Fibrillation | 2017 |
Action potential alternans in the right ventricular outflow tract in a patient with asymptomatic Brugada syndrome.
Topics: Action Potentials; Aged; Anti-Arrhythmia Agents; Brugada Syndrome; Electrocardiography; Humans; Lido | 2009 |
Nifekalant versus lidocaine for in-hospital shock-resistant ventricular fibrillation or tachycardia.
Topics: Aged; Anti-Arrhythmia Agents; Chi-Square Distribution; Female; Humans; Lidocaine; Male; Middle Aged; | 2010 |
Predicting drug-induced slowing of conduction and pro-arrhythmia: identifying the 'bad' sodium current blockers.
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; CHO Cells; Cricetinae; Cricetulus; Drug Evalu | 2010 |
What variables were associated with the inducibility of ventricular fibrillation during electrophysiologic stimulation test in patients without apparent organic heart disease?
Topics: Brugada Syndrome; Electric Stimulation; Electrocardiography; Female; Humans; Lidocaine; Male; Middle | 2010 |
Ventricular fibrillation diagnosed during electrophysiological study for non-sustained tachycardia.
Topics: Adult; Anti-Arrhythmia Agents; Brugada Syndrome; Electrocardiography; Humans; Japan; Lidocaine; Male | 2010 |
Differential effects of four xylidine derivatives in the model of ischemia- and re-perfusion-induced arrhythmias in rats in vivo.
Topics: Amides; Anesthetics, Local; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Blood Pressure; C | 2010 |
Efficacy of amiodarone on refractory ventricular fibrillation resistant to lidocaine and cardioversion during weaning from cardiopulmonary bypass in aortic valve replacement for severe aortic stenosis with left ventricular hypertrophy.
Topics: Aged; Amiodarone; Anesthesia, General; Anti-Arrhythmia Agents; Aortic Valve; Aortic Valve Stenosis; | 2010 |
Antiarrhythmic drug therapy for sustained ventricular arrhythmias complicating acute myocardial infarction.
Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Cohort Studies; Confidence Intervals; Dose-Response Relati | 2011 |
Drug therapy for sustained ventricular arrhythmias complicating acute myocardial infarction: What does the crystal ball tell you?
Topics: Amiodarone; Anti-Arrhythmia Agents; Critical Care; Critical Illness; Electrocardiography; Female; Hu | 2011 |
First direct comparison of the late sodium current blocker ranolazine to established antiarrhythmic agents in an ischemia/reperfusion model.
Topics: Acetanilides; Animals; Anti-Arrhythmia Agents; Enzyme Inhibitors; Female; Infusions, Intravenous; In | 2011 |
Role of KATP channels in the maintenance of ventricular fibrillation in cardiomyopathic human hearts.
Topics: Action Potentials; Animals; Cardiomyopathy, Dilated; Endocardium; Glyburide; Humans; In Vitro Techni | 2011 |
House arrest. When the fallen is one of our own, emotions run high.
Topics: Cardiopulmonary Resuscitation; Defibrillators; Emergency Medical Services; Emergency Medical Technic | 2011 |
Amiodarone versus lidocaine for shock-resistant ventricular fibrillation.
Topics: Amiodarone; Anti-Arrhythmia Agents; Cost-Benefit Analysis; Heart Arrest; Hospitalization; Humans; Li | 2002 |
Amiodarone versus lidocaine for shock-resistant ventricular fibrillation.
Topics: Amiodarone; Anti-Arrhythmia Agents; Hospitalization; Humans; Lidocaine; Survival Rate; Time Factors; | 2002 |
Amiodarone versus lidocaine for shock-resistant ventricular fibrillation.
Topics: Amiodarone; Anti-Arrhythmia Agents; Cost-Benefit Analysis; Hospitalization; Humans; Lidocaine; Survi | 2002 |
Amiodarone versus lidocaine for shock-resistant ventricular fibrillation.
Topics: Amiodarone; Anti-Arrhythmia Agents; Double-Blind Method; Excipients; Humans; Lidocaine; Placebos; Po | 2002 |
Pilsicanide-induced marked T wave alternans and ventricular fibrillation in a patient with Brugada syndrome.
Topics: Adult; Anti-Arrhythmia Agents; Bundle-Branch Block; Electrocardiography; Humans; Lidocaine; Long QT | 2002 |
Secondary cross-clamping and blood cardioplegia for refractory ventricular fibrillation after aortic cross-clamp removal.
Topics: Anti-Arrhythmia Agents; Aortic Diseases; Cardiac Surgical Procedures; Cardioplegic Solutions; Combin | 2002 |
[Brugada syndrome occurring in an identical twin: a case report].
Topics: Anti-Arrhythmia Agents; Bundle-Branch Block; Diseases in Twins; Electrocardiography; Humans; Lidocai | 2002 |
Risk stratification for asymptomatic patients with Brugada syndrome.
Topics: Adult; Aged; Anti-Arrhythmia Agents; Bundle-Branch Block; Cardiac Pacing, Artificial; Electrocardiog | 2003 |
[Efficacy of Nifekalant hydrochloride for life-threatening ventricular tachyarrhythmias in patients with resistance to lidocaine: a study of patients with out-of-hospital cardiac arrest].
Topics: Adult; Aged; Anti-Arrhythmia Agents; Cardiopulmonary Resuscitation; Drug Resistance; Emergency Medic | 2003 |
Enhancement of J-ST-segment elevation by the glucose and insulin test in Brugada syndrome.
Topics: Adult; Anti-Arrhythmia Agents; Bundle-Branch Block; Electrocardiography; Glucose; Heart Arrest; Huma | 2003 |
Electrical heterogeneity and arrhythmogenesis: importance of conduction velocity dispersion.
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Coronary Vessels; Disease Models, Animal; Ele | 2003 |
Intravenous administration of class I antiarrhythmic drug induced T wave alternans in an asymptomatic Brugada syndrome patient.
Topics: Amiodarone; Anti-Arrhythmia Agents; Bundle-Branch Block; Cardiac Pacing, Artificial; Electrocardiogr | 2003 |
THE CHEMOTHERAPY OF CARDIAC ARREST.
Topics: Acidosis; Arrhythmias, Cardiac; Bicarbonates; Brugada Syndrome; Cardiac Conduction System Disease; C | 1965 |
ELECTRICAL CONVERSION OF VENTRICUALAR TACHYCARDIA.
Topics: Coronary Disease; Drug Therapy; Electric Countershock; Electrocardiography; Humans; Lidocaine; Proca | 1965 |
[Defibrillating action of lidocaine and novocaine].
Topics: Anesthetics; Anesthetics, Local; Electric Countershock; Lidocaine; Procaine; Ventricular Fibrillatio | 1955 |
Electrical storm: case series and review of management.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Amiodarone; Anti-Arrhythmia Agents; Anti-Obesity Agents; B | 2003 |
Further evidence that melanocortins prevent myocardial reperfusion injury by activating melanocortin MC3 receptors.
Topics: alpha-MSH; Animals; Coronary Disease; Cosyntropin; Female; FMRFamide; gamma-MSH; Hypotension; Inject | 2003 |
The significant role of membrane stabilization in hypothermic cardioplegic cardiac preservation in a canine experimental model.
Topics: Animals; Betamethasone; Biomarkers; Calcium; Cardioplegic Solutions; Creatine Kinase; Creatine Kinas | 1992 |
[Brugada syndrome associated with ventricular fibrillation induced by administration of pilsicainide: a case report].
Topics: Anti-Arrhythmia Agents; Atrial Fibrillation; Electrocardiography; Electrophysiology; Humans; Lidocai | 2003 |
Brugada syndrome-like ST-segment elevation increase exacerbated by vomiting.
Topics: Acetylcholine; Anti-Arrhythmia Agents; Coronary Vessels; Electrocardiography; Humans; Infusions, Int | 2004 |
Protection against ventricular arrhythmias and cardiac death using adenosine and lidocaine during regional ischemia in the in vivo rat.
Topics: Adenosine; Animals; Anti-Arrhythmia Agents; Drug Combinations; Hemodynamics; Lidocaine; Male; Myocar | 2004 |
Prevention of primary ventricular fibrillation in acute myocardial infarction with prophylactic lidocaine.
Topics: Aged; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Chemoprevention; Female; Humans; Incidence; Lido | 2004 |
Salvage application of secondary blood cardioplegia in intractable ventricular fibrillation.
Topics: Adult; Amiodarone; Anti-Arrhythmia Agents; Blood Gas Analysis; Cardiopulmonary Bypass; Dose-Response | 2004 |
[The filter region of the myocardial Na channel, together with ion selectivity, controls pharmacodynamics of anti-arrhythmia agents--an analysis using the channel altered by idiopathic ventricular fibrillation].
Topics: Anti-Arrhythmia Agents; Filtration; Heart; Humans; In Vitro Techniques; Lidocaine; Mexiletine; Muscl | 2004 |
Primary ventricular fibrillation cannot be buried; it never died.
Topics: Anti-Arrhythmia Agents; Bias; Cross-Sectional Studies; Hospital Mortality; Humans; Incidence; Lidoca | 2005 |
Comparison of nifekalant and lidocaine for the treatment of shock-refractory ventricular fibrillation.
Topics: Aged; Anti-Arrhythmia Agents; Cardiopulmonary Resuscitation; Epinephrine; Female; Heart Arrest; Huma | 2006 |
Cellular basis for trigger and maintenance of ventricular fibrillation in the Brugada syndrome model: high-resolution optical mapping study.
Topics: Action Potentials; Animals; Cardiovascular Agents; Disease Models, Animal; Dogs; Electrocardiography | 2006 |
Antiarrhythmic activity of taurhythman.
Topics: Aconitine; Alkanesulfonic Acids; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cardiotonic | 2005 |
The full stomach test as a novel diagnostic technique for identifying patients at risk of Brugada syndrome.
Topics: Adult; Brugada Syndrome; Circadian Rhythm; Electrocardiography; Electrophysiologic Techniques, Cardi | 2006 |
Spontaneous polymorphic ventricular tachycardia after administration of pilsicainide in a patient resuscitated from ventricular fibrillation.
Topics: Adult; Anti-Arrhythmia Agents; Cardiopulmonary Resuscitation; Electric Countershock; Humans; Lidocai | 2006 |
Multiple premature beats triggered ventricular arrhythmias during pilsicainide infusion in a patient with inferior ST-segment elevation.
Topics: Adolescent; Anti-Arrhythmia Agents; Atrial Flutter; Electrocardiography; Humans; Infusions, Intraven | 2006 |
Limiting sarcolemmal Na+ entry during resuscitation from ventricular fibrillation prevents excess mitochondrial Ca2+ accumulation and attenuates myocardial injury.
Topics: Animals; Anti-Arrhythmia Agents; Blood Pressure; Calcium; Coronary Circulation; Disease Models, Anim | 2007 |
Effects of pericardial lidocaine on hemodynamic parameters and responses in dogs anesthetized with midazolam and fentanyl.
Topics: Anesthesia; Animals; Coronary Artery Bypass, Off-Pump; Dogs; Fentanyl; Heart Rate; Lidocaine; Midazo | 2007 |
Antiarrhythmic effect of newly synthesized compound 44Bu on model of aconitine-induced arrhythmia -- compared to lidocaine.
Topics: Aconitine; Anesthetics, Local; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Benzoates; Lid | 2007 |
[Case of intractable ventricula fibrillation by a multicomponent dietary supplement containing ephedra and caffeine overdose].
Topics: Adult; Caffeine; Dietary Supplements; Drug Overdose; Drug Synergism; Electric Countershock; Ephedra; | 2007 |
Recurrent life-threatening ventricular dysrhythmias associated with acute hydrofluoric acid ingestion: observations in one case and implications for mechanism of toxicity.
Topics: Aged, 80 and over; Calcium Chloride; Electric Countershock; Electrocardiography; Emergency Service, | 2008 |
Re: Clinical significance of macroscopic T-wave alternans after sodium channel blocker administration in patients with Brugada syndrome.
Topics: Brugada Syndrome; Electrocardiography; Female; Humans; Lidocaine; Male; Middle Aged; Sodium Channel | 2008 |
Control of recurrent ventricular fibrillation by transvenous pacing in the absence of heart block.
Topics: Aged; Atropine; Electric Countershock; Heart Block; Heart Massage; Humans; Lidocaine; Male; Pacemake | 1967 |
The coronary care unit. A year's experience in a community hospital.
Topics: Aged; Anticoagulants; Atropine; Bradycardia; Community Health Services; Diet Therapy; Digitalis Glyc | 1967 |
The antifibrillatory potency of aprindine, mexiletine, tocainide and lignocaine compared on Langendorff-perfused hearts of rabbits and guinea-pigs.
Topics: Anilides; Animals; Anti-Arrhythmia Agents; Aprindine; Dose-Response Relationship, Drug; Female; Guin | 1980 |
How does lignocaine prevent ventricular fibrillation?
Topics: Calmodulin; Drug Interactions; Humans; Lidocaine; Myocardial Infarction; Ventricular Fibrillation | 1981 |
[Ventricular heart rhythm disorders in acute myocardial infarction].
Topics: Adrenergic beta-Antagonists; Animals; Arrhythmias, Cardiac; Calcium; Dogs; Heart Ventricles; Humans; | 1983 |
Recurrent ventricular fibrillation after subarachnoid haemorrhage. Dose-related effect of lidocaine infusion.
Topics: Dose-Response Relationship, Drug; Electrocardiography; Female; Heart; Humans; Lidocaine; Middle Aged | 1982 |
The efficacy of Ajmaline in ventricular arrhythmias after failure of lidocaine therapy in the acute phase of myocardial infarction.
Topics: Ajmaline; Cardiac Complexes, Premature; Digoxin; Heart Conduction System; Heart Failure; Humans; Lid | 1983 |
[Value of lidocaine in the prevention of ventricular arrhythmias in the acute phase of myocardial infarct].
Topics: Adult; Aged; Arrhythmias, Cardiac; Cardiac Complexes, Premature; Female; Heart Ventricles; Humans; L | 1983 |
Management of ventricular dysrhythmias in the prehospital and emergency department setting.
Topics: Arrhythmias, Cardiac; Bretylium Compounds; Bretylium Tosylate; Coronary Disease; Electric Countersho | 1984 |
Antifibrillatory drugs: the case for lidocaine and procainamide.
Topics: Electrophysiology; Heart; Humans; Lidocaine; Procainamide; Ventricular Fibrillation | 1984 |
Pre- and in-hospital antiarrhythmic prevention of ventricular fibrillation complicating acute myocardial infarction.
Topics: Aged; Dose-Response Relationship, Drug; Electric Countershock; Humans; Infusions, Parenteral; Lidoca | 1984 |
[Prophylaxis of primary ventricular fibrillation in the acute phase of acute myocardial infarct].
Topics: Acute Disease; Humans; Lidocaine; Myocardial Infarction; Ventricular Fibrillation | 1984 |
Epicardial, endocardial and transmural mapping in assessing electrophysiological effects of 14-C lidocaine and 14-C propafenone on activation times in experimental chronic myocardial infarction. Correlations with myocardial drugs concentrations.
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Carbon Radioisotopes; Coronary Circulation; D | 1984 |
Lidocaine prophylaxis in myocardial infarction: a concept whose time has come.
Topics: Aged; Humans; Lidocaine; Myocardial Infarction; Premedication; Ventricular Fibrillation | 1983 |
Routine prophylactic lidocaine in acute myocardial infarction.
Topics: Aged; Confusion; Coronary Care Units; Drug Administration Schedule; Electrocardiography; Female; Hum | 1983 |
Treatment and prophylaxis of ventricular arrhythmias in acute myocardial infarction.
Topics: Arrhythmias, Cardiac; Humans; Lidocaine; Metoprolol; Myocardial Infarction; Resuscitation; Time Fact | 1983 |
[Intensive monitoring ward for coronary patients].
Topics: Acute Disease; Coronary Care Units; Hospitalization; Humans; Lidocaine; Monitoring, Physiologic; Myo | 1984 |
[Lidocaine prophylaxis in acute myocardial infarct].
Topics: Animals; Dogs; Humans; Lidocaine; Myocardial Infarction; Ventricular Fibrillation | 1984 |
Göteborg Metoprolol Trial: effects on arrhythmias.
Topics: Adult; Aged; Arrhythmias, Cardiac; Clinical Trials as Topic; Double-Blind Method; Female; Heart Arre | 1984 |
Tocainide for drug-resistant ventricular arrhythmias: efficacy, side effects, and lidocaine responsiveness for predicting tocainide success.
Topics: Aged; Anilides; Dose-Response Relationship, Drug; Female; Glomerulonephritis; Humans; Lidocaine; Mal | 1980 |
Tocainide for refractory symptomatic ventricular arrhythmias.
Topics: Adult; Aged; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Electrophysiology; Exercise Test; Female; | 1982 |
[Incidence of ventricular fibrillation in acute myocardial infarction with and without the use of lidocaine].
Topics: Coronary Care Units; Humans; Lidocaine; Myocardial Infarction; Prognosis; Ventricular Fibrillation | 1983 |
[Lidocaine prevention of ventricular fibrillation in acute myocardial infarct at the first-aid and early hospital stages].
Topics: Adult; First Aid; Heart Failure; Hospitalization; Humans; Lidocaine; Middle Aged; Myocardial Infarct | 1983 |
Lignocaine therapy in myocardial infarction.
Topics: Humans; Lidocaine; Myocardial Infarction; Ventricular Fibrillation | 1982 |
Should prophylactic antiarrhythmic drug therapy be used in acute myocardial infarction?
Topics: Acute Disease; Humans; Lidocaine; Metabolism; Methods; Myocardial Infarction; Time Factors; Ventricu | 1982 |
The effects of diltiazem and reduced serum ionized calcium on ischemic ventricular fibrillation in the dog.
Topics: Animals; Benzazepines; Calcium; Citrates; Citric Acid; Coronary Circulation; Coronary Disease; Dilti | 1982 |
Should prophylactic lidocaine be routinely used in patients suspected of acute myocardial infarction?
Topics: Anti-Arrhythmia Agents; Humans; Lidocaine; Myocardial Infarction; Ventricular Fibrillation | 1982 |
Effects of sulfinpyrazone on ventricular vulnerability in the normal and the ischemic heart.
Topics: Animals; Coronary Disease; Dogs; Female; Heart; Heart Conduction System; Lidocaine; Male; Myocardial | 1982 |
Ventricular fibrillation complicating acute myocardial infarction: reasons against the routine use of lidocaine.
Topics: Aged; Coronary Care Units; Female; Humans; Lidocaine; Male; Middle Aged; Myocardial Infarction; Vent | 1982 |
Prophylactic lidocaine: uncertain benefits in emergency settings.
Topics: Emergency Medical Services; Ethics, Medical; Humans; Lidocaine; Myocardial Infarction; Research Desi | 1982 |
The efficacy of lidocaine in ventricular fibrillation due to coronary artery ligation: endotracheal vs intravenous use.
Topics: Animals; Coronary Vessels; Female; Injections, Intravenous; Intubation, Intratracheal; Lidocaine; Ma | 1982 |
Tiapamil in the treatment of lidocaine-resistant ventricular arrhythmias complicating acute myocardial infarction.
Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Blood Pressure; Calcium Channel Blockers; Drug Resista | 1982 |
[Relationship between lidocaine-induced suppression of premature excitation and reduced possibility of the appearance of ventricular fibrillation in myocardial infarction].
Topics: Action Potentials; Heart Conduction System; Humans; Lidocaine; Myocardial Infarction; Ventricular Fi | 1982 |
[Adult respiratory distress syndrome (ARDS) after poisoning by local anesthetics].
Topics: Arrhythmias, Cardiac; Child, Preschool; Dibucaine; Female; Humans; Intracranial Pressure; Lidocaine; | 1982 |
[The importance of premonitory arrhythmias of primary ventricular fibrillation (PVF) in myocardial infarct].
Topics: Arrhythmias, Cardiac; Electric Countershock; Humans; Lidocaine; Myocardial Infarction; Ventricular F | 1981 |
Lidocaine in prehospital countershock refractory ventricular fibrillation.
Topics: Anti-Arrhythmia Agents; Drug Evaluation; Electric Countershock; Emergency Medical Technicians; Femal | 1981 |
Recurrence of ventricular fibrillation in acute ischemic heart disease.
Topics: Acute Disease; Anti-Arrhythmia Agents; Coronary Disease; Female; Heart Arrest; Humans; Lidocaine; Ma | 1981 |
Improved observational method for studying therapeutic efficacy. Suggestive evidence that lidocaine prophylaxis prevents death in acute myocardial infarction.
Topics: Acute Disease; Aged; Clinical Trials as Topic; Evaluation Studies as Topic; Humans; Lidocaine; Male; | 1981 |
Studies on the preventive method of lowered ventricular fibrillation threshold during experimental acute myocardial infarctions. A comparison between disopyramide phosphate and lidocaine.
Topics: Animals; Disease Models, Animal; Disopyramide; Dogs; Dose-Response Relationship, Drug; Injections, I | 1981 |
[Therapy of ventricular tachyarrhythmias refractory to lidocaine with propafenone (author's transl)].
Topics: Administration, Oral; Adolescent; Adult; Aged; Drug Evaluation; Drug Resistance; Female; Heart Ventr | 1981 |
Mexiletine therapy in 15 patients with drug-resistant ventricular tachycardia.
Topics: Adult; Aged; Dose-Response Relationship, Drug; Drug Resistance; Electrocardiography; Female; Humans; | 1980 |
The relationship between the repetitive extrasystole threshold and the ventricular fibrillation threshold in the dog. Non-parallel changes following pharmacological intervention.
Topics: Acebutolol; Animals; Dogs; Electric Stimulation; Lidocaine; Myocardial Contraction; Systole; Time Fa | 1980 |
Ventricular tachyarrhythmias in regional myocardial hyperkalemia: efficacy of three antiarrhythmic agents.
Topics: Animals; Coronary Disease; Disease Models, Animal; Dogs; Electrocardiography; Heart Conduction Syste | 1980 |
Prolonged QT interval, atrioventricular block, and torsade de pointes after antiarrhythmic therapy.
Topics: Aged; Disopyramide; Electrocardiography; Female; Heart; Heart Block; Humans; Lidocaine; Pyridines; T | 1980 |
[Intramuscular administration of lignocaine for prevention of life-threatening arrhythmia in acute myocardial infarct].
Topics: Acute Disease; Adult; Aged; Female; Humans; Injections, Intramuscular; Lidocaine; Male; Middle Aged; | 1980 |
First-aid treatment for acute coronary thrombosis.
Topics: Acute Disease; Coronary Disease; Digoxin; Humans; Lidocaine; Tachycardia; Ventricular Fibrillation | 1980 |
Failure of antiarrhythmic drugs to prevent experimental reperfusion ventricular fibrillation.
Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Coronary Vessels; Dogs; Lidocaine; Ligation; Perfusion; | 1981 |
Prophylactic lidocaine.
Topics: Humans; Lidocaine; Myocardial Infarction; Ventricular Fibrillation | 1980 |
Reappraisal of lignocaine therapy in management of myocardial infarction.
Topics: Aged; Drug Administration Schedule; Female; Humans; Lidocaine; Male; Middle Aged; Myocardial Infarct | 1981 |
Facilitation of reentry by lidocaine in canine myocardial infarction.
Topics: Animals; Blood Pressure; Cardiac Complexes, Premature; Dogs; Electric Stimulation; Electrocardiograp | 1994 |
Profibrillatory effects of lidocaine in the acutely ischemic porcine heart.
Topics: Action Potentials; Animals; Cardiac Pacing, Artificial; Coronary Disease; Disease Models, Animal; El | 1995 |
Ventricular defibrillation in canines with chronic infarction, and effects of lidocaine and procainamide.
Topics: Animals; Dogs; Electric Countershock; Female; Hemodynamics; Lidocaine; Male; Myocardial Infarction; | 1993 |
Lidocaine converts inducible ventricular fibrillation into sustained ventricular tachycardia in conscious dogs with recent myocardial infarction.
Topics: Animals; Dogs; Electrocardiography; Female; Heart Conduction System; Heart Rate; Lidocaine; Male; My | 1994 |
[Circulatory arrest after splanchnic neurolysis with phenol in unresectable cancer of the pancreas].
Topics: Aged; Aged, 80 and over; Female; Heart Arrest; Humans; Lidocaine; Male; Pain, Postoperative; Pancrea | 1994 |
Sodium bicarbonate may improve outcome in dogs with brief or prolonged cardiac arrest.
Topics: Acidosis; Animals; Atropine; Blood Circulation; Dogs; Epinephrine; Heart Arrest; Hemodynamics; Hydro | 1995 |
Attenuation of antifibrillatory effects of lidocaine by its metabolite, glycylxylidide: application of modulated receptor hypothesis.
Topics: Animals; Dogs; Drug Interactions; Electrophysiology; Lidocaine; Ventricular Fibrillation; Ventricula | 1994 |
The effects of lidocaine on the vulnerable period during ventricular fibrillation.
Topics: Animals; Dogs; Electrophysiology; Female; Heart; Lidocaine; Male; Shock, Cardiogenic; Ventricular Fi | 1994 |
Early afterdepolarization formation in cardiac myocytes: analysis of phase plane patterns, action potential, and membrane currents.
Topics: Action Potentials; Animals; Arrhythmias, Cardiac; Cardiotonic Agents; Cells, Cultured; Cnidarian Ven | 1994 |
Survival after cardiac arrest outside hospital over a 12-year period in Gothenburg.
Topics: Adult; Age Distribution; Aged; Ambulances; Cardiopulmonary Resuscitation; Electric Countershock; Epi | 1994 |
Sixty-six episodes of ventricular fibrillation within four hours: electrical stability restored by propafenone.
Topics: Amiodarone; Electric Countershock; Humans; Injections, Intravenous; Lidocaine; Male; Middle Aged; My | 1994 |
Advantages and limitations of metaanalytic regressions of clinical trials data.
Topics: Acute Disease; Confounding Factors, Epidemiologic; Crohn Disease; Humans; Immunosuppression Therapy; | 1994 |
Effects of amiodarone on refractory ventricular fibrillation in acute myocardial infarction: experimental study.
Topics: Amiodarone; Animals; Disease Models, Animal; Dogs; Electric Stimulation; Epinephrine; Female; Heart | 1994 |
[First-pass effect of dauricine].
Topics: Alkaloids; Animals; Anti-Arrhythmia Agents; Benzylisoquinolines; Ear; Female; Forelimb; Infusions, I | 1993 |
Antifibrillatory and electrophysiologic actions of moricizine alone and in combination with lidocaine: a prospective, randomized trial.
Topics: Animals; Blood Pressure; Disease Models, Animal; Double-Blind Method; Electrocardiography; Lidocaine | 1993 |
Use of lignocaine in ventricular defibrillation?
Topics: Cardiopulmonary Resuscitation; Humans; Lidocaine; Ventricular Fibrillation | 1993 |
Lidocaine cardioplegia for prevention of reperfusion ventricular fibrillation.
Topics: Cardioplegic Solutions; Coronary Artery Bypass; Female; Heart Arrest, Induced; Heart Block; Heart Va | 1993 |
Effects of a new amiodarone-like agent, SR 33589, in comparison to amiodarone, D,L-sotalol, and lignocaine, on ischemia-induced ventricular arrhythmias in anesthetized pigs.
Topics: Amiodarone; Analysis of Variance; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Benzofurans | 1995 |
[Anesthesiologic management in cardiomyoplasty].
Topics: Adult; Aged; Anesthesia, General; Anti-Arrhythmia Agents; Cardiomyoplasty; Cardiotonic Agents; Dobut | 1995 |
SR 33589, a new amiodarone-like agent: effect on ischemia- and reperfusion-induced arrhythmias in anesthetized rats.
Topics: Administration, Oral; Amiodarone; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Benzofurans | 1995 |
Mechanism of antiarrhythmic drug-induced changes in defibrillation threshold: role of potassium and sodium channel conductance.
Topics: Animals; Anti-Arrhythmia Agents; Cesium; Lidocaine; Potassium Channels; Sodium Channels; Swine; Vent | 1996 |
Idiopathic ventricular fibrillation initiated by a short-coupled ventricular premature beat.
Topics: Adult; Anti-Arrhythmia Agents; Cardiac Complexes, Premature; Drug Therapy, Combination; Electrocardi | 1996 |
Antifibrillatory effect of esmolol alone and in combination with lidocaine.
Topics: Adrenergic beta-Antagonists; Animals; Anti-Arrhythmia Agents; Blood Pressure; Drug Therapy, Combinat | 1996 |
[Comparative anti-arrhythmia activity of rinocaine and lidocaine].
Topics: Anesthetics, Local; Animals; Anti-Arrhythmia Agents; Cats; Dogs; Electrocardiography; Female; In Vit | 1996 |
Hypertonic saline does not reverse the sodium channel blocking actions of lidocaine: evidence from electrophysiologic and defibrillation studies.
Topics: Action Potentials; Animals; Electrophysiology; Heart Conduction System; Lidocaine; Potassium; Saline | 1997 |
Effects of blockade of fast and slow inward current channels on ventricular fibrillation in the pig heart.
Topics: Animals; Anti-Arrhythmia Agents; Calcium Channel Blockers; Disopyramide; Electrocardiography; Flecai | 1996 |
Ischaemia-induced loss or reversal of the effects of the class I antiarrhythmic drugs on vulnerability to fibrillation.
Topics: Animals; Anti-Arrhythmia Agents; Blood Pressure; Coronary Vessels; Disopyramide; Electric Stimulatio | 1997 |
Lidocaine: work still in progress.
Topics: Ambulances; Anti-Arrhythmia Agents; Cardiopulmonary Resuscitation; Epinephrine; Humans; Lidocaine; N | 1997 |
Lidocaine in out-of-hospital ventricular fibrillation. Does it improve survival?
Topics: Adult; Aged; Aged, 80 and over; Anti-Arrhythmia Agents; Cardiopulmonary Resuscitation; Electrocardio | 1997 |
Effects of lidocaine, ajmaline, and diltiazem on ventricular defibrillation energy requirements in isolated rabbit heart.
Topics: Ajmaline; Analysis of Variance; Animals; Anti-Arrhythmia Agents; Cardiovascular Agents; Defibrillato | 1997 |
Electrophysiologic effects of sodium channel blockade on anisotropic conduction and conduction block in canine myocardium: preferential slowing of longitudinal conduction by flecainide versus disopyramide or lidocaine.
Topics: Animals; Anti-Arrhythmia Agents; Cardiac Complexes, Premature; Disopyramide; Dogs; Electric Conducti | 1997 |
[Etiologies of electric storm].
Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Bretylium Tosylate; Electric Countershock; Female; Hemodyn | 1997 |
[Effect of KLN-93 on ventricular fibrillation induced by reperfusion or electrical stimulation in cats].
Topics: 4-Aminobenzoic Acid; Anesthetics, Local; Animals; Anti-Arrhythmia Agents; Cats; Dose-Response Relati | 1997 |
Contrast-medium-induced ventricular fibrillation: arrhythmogenic mechanisms and the role of antiarrhythmic drugs in dogs.
Topics: Action Potentials; Amiodarone; Animals; Anti-Arrhythmia Agents; Catheterization; Contrast Media; Cor | 1995 |
High-dose lidocaine does not affect defibrillation efficacy: implications for defibrillation mechanisms.
Topics: Animals; Dose-Response Relationship, Drug; Electric Countershock; Electrophysiology; Heart; Heart Co | 1998 |
Lidocaine increases the ventricular fibrillation threshold during bupivacaine-induced cardiotoxicity in pigs.
Topics: Anesthetics, Combined; Anesthetics, Local; Animals; Anti-Arrhythmia Agents; Bupivacaine; Electrocard | 1998 |
Effects of lidocaine and mexiletine on defibrillation energy requirements in animals treated with flecainide.
Topics: Animals; Anti-Arrhythmia Agents; Dogs; Electric Countershock; Flecainide; Lidocaine; Mexiletine; Ven | 1998 |
Intracoronary flecainide induces ST alternans and reentrant arrhythmia on intact canine heart: A role of 4-aminopyridine-sensitive current.
Topics: 4-Aminopyridine; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Coronary Vessels; Disopyrami | 1999 |
The technique of reversing ventricular fibrillation: improve the odds of success with this five-phase approach.
Topics: Bretylium Compounds; Clinical Protocols; Electric Countershock; Epinephrine; Humans; Intubation, Int | 1994 |
Grand mal seizure during cardiopulmonary bypass: probable lidocaine toxicity.
Topics: Anesthetics, Local; Aortic Valve; Aortic Valve Stenosis; Cardiopulmonary Bypass; Epilepsy, Tonic-Clo | 1999 |
Nicorandil, a potassium channel opener, abolished torsades de pointes in a patient with complete atrioventricular block.
Topics: Aged; Anesthetics, Local; Anti-Arrhythmia Agents; Bradycardia; Cardiotonic Agents; Electrocardiograp | 1999 |
Ventricular arrhythmias and the use of antiarrhythmic drugs after cardiovascular surgery.
Topics: Amiodarone; Anti-Arrhythmia Agents; Bretylium Compounds; Cardiovascular Surgical Procedures; Clinica | 1998 |
Protective effect of FR168888, a new Na+/H+ exchange inhibitor, on ischemia and reperfusion-induced arrhythmia and myocardial infarction in rats: in comparison with other cardioprotective compounds.
Topics: Anesthesia; Animals; Arrhythmias, Cardiac; Benzyl Alcohol; Benzyl Alcohols; Diltiazem; Dose-Response | 1999 |
[Multi-recurrent cardiac arrest: when to discontinue cardiopulmonary resuscitation?].
Topics: Anti-Arrhythmia Agents; Cardiopulmonary Resuscitation; Coma; Combined Modality Therapy; Coronary Car | 2000 |
Anisotropic effects of sodium channel blockers on the wavelength for ventricular excitation in dogs.
Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Disopyramide; Dogs; Electr | 2000 |
Ventricular arrhythmias with or without programmed electrical stimulation after incremental overdosage with lidocaine, bupivacaine, levobupivacaine, and ropivacaine.
Topics: Amides; Anesthetics, Local; Animals; Bupivacaine; Cardiac Pacing, Artificial; Dogs; Drug Overdose; L | 2000 |
Role of sodium channels in ventricular fibrillation: a study in nonischemic isolated hearts.
Topics: Anesthetics, Local; Animals; Arrhythmias, Cardiac; Cats; Echocardiography, Three-Dimensional; Electr | 2000 |
Relatively benign clinical course in asymptomatic patients with brugada-type electrocardiogram without family history of sudden death.
Topics: Adult; Anti-Arrhythmia Agents; Bundle-Branch Block; Death, Sudden, Cardiac; Electrocardiography; Ele | 2001 |
Lidocaine increases the proarrhythmic effects of monophasic but not biphasic shocks.
Topics: Animals; Anti-Arrhythmia Agents; Cardiac Pacing, Artificial; Electric Countershock; Electrocardiogra | 2001 |
Paradoxic abbreviation of repolarization in epicardium of the right ventricular outflow tract during augmentation of Brugada-type ST segment elevation.
Topics: Anti-Arrhythmia Agents; Bundle-Branch Block; Cardiotonic Agents; Electrocardiography; Heart Ventricl | 2001 |
Limited antifibrillatory effectiveness of clinically relevant concentrations of class I antiarrhythmics in isolated perfused rat hearts.
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Coronary Circulation; Electrocardiography; Fl | 2002 |
J wave and ST segment elevation in the inferior leads: a latent type of variant Brugada syndrome?
Topics: Adult; Bundle-Branch Block; Diagnosis, Differential; Electrocardiography; Humans; Lidocaine; Male; S | 2002 |
Mechanisms contributing to dysrhythmias induced by ischemia and their therapeutic implications.
Topics: Adrenergic beta-Antagonists; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Coronary Disease | 1978 |
Cyclic adenosine monophosphate, ventricular fibrillation, and antiarrhythmic drugs.
Topics: Adrenergic beta-Antagonists; Animals; Anti-Arrhythmia Agents; Calcium; Coronary Disease; Cyclic AMP; | 1976 |
Arrhythmias in myocardial infarction.
Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atropine; Bradycardia; Cardiac Complexes, Premature; D | 1976 |
Should premature ventricular beats be treated in the ambulatory patient? A protagonist's view.
Topics: Adult; Aged; Alprenolol; Ambulatory Care; Cardiac Complexes, Premature; Death, Sudden; Electrocardio | 1977 |
Disopyramide--an effective treatment for lignocaine resistant ventricular dysrhythmias.
Topics: Arrhythmias, Cardiac; Cardiac Complexes, Premature; Disopyramide; Female; Humans; Lidocaine; Male; M | 1979 |
Elevation of ventricular defibrillation threshold in dogs by antiarrhythmic drugs.
Topics: Animals; Anti-Arrhythmia Agents; Blood Pressure; Dogs; Lidocaine; Phenytoin; Quinidine; Ventricular | 1979 |
Effects of bretylium and lidocaine on ventricular fibrillation in the isolated rabbit heart.
Topics: Animals; Bretylium Compounds; Electric Countershock; Electric Stimulation; Electrodes; Heart; Heart | 1975 |
Treatment and prevention of primary ventricular fibrillation complicating acute myocardial infarction.
Topics: Electric Countershock; Humans; Lidocaine; Myocardial Infarction; Ventricular Fibrillation | 1977 |
The treatment of ventricular arrhythmias in acute myocardial infarction.
Topics: Anti-Arrhythmia Agents; Electric Countershock; Electrocardiography; Humans; Lidocaine; Mexiletine; M | 1979 |
Treatment of arrhythmias in the Wolff-Parkinson-White syndrome.
Topics: Administration, Oral; Atrial Fibrillation; Disopyramide; Humans; Injections, Intravenous; Lidocaine; | 1979 |
Hyperventilation in tricyclic antidepressant poisoning.
Topics: Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Female; Humans; Lidocaine; Physostigmine; Re | 1979 |
[Hazards of 2% levorenone eyedrops].
Topics: Adult; Anesthesia, Inhalation; Drug Combinations; Drug Interactions; Epinephrine; Female; Halothane; | 1979 |
[Preventive effectiveness of verapamil in ventricular fibrillation in the first 24 hours after myocardial infarct].
Topics: Acute Disease; Adult; Aged; Female; Humans; Lidocaine; Male; Middle Aged; Myocardial Infarction; Ven | 1979 |
Electrophysiologic properties of a new antiarrhythmic drug--tocainide.
Topics: Action Potentials; Anilides; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cardiac Pacing, | 1978 |
Ventricular arrhythmias associated with coronary artery occlusion and reperfusion in the isolated perfused rat heart: a model for assessment of antifibrillatory action of antiarrhythmic agents.
Topics: Animals; Arrhythmias, Cardiac; Coronary Disease; In Vitro Techniques; Lidocaine; Perfusion; Potassiu | 1978 |
[Prevention of ventricular fibrillation in animal experiments].
Topics: Ajmaline; Animals; Anti-Arrhythmia Agents; Drug Evaluation; Lidocaine; Pindolol; Rats; Ventricular F | 1978 |
Effects of tocainide on ventricular fibrillation threshold. Comparison with lidocaine.
Topics: Animals; Anti-Arrhythmia Agents; Dogs; Dose-Response Relationship, Drug; Lidocaine; Myocardial Contr | 1978 |
[Current viewpoints on prevention and treatment of ventricular fibrillation in acute heart infarct].
Topics: Acute Disease; Digoxin; Drug Therapy, Combination; Electric Countershock; Humans; Lidocaine; Myocard | 1978 |
[Primary ventricular fibrillation during the acute phase of myocardial infarction (author's transl)].
Topics: Acute Disease; Adult; Age Factors; Aged; Anti-Arrhythmia Agents; Humans; Lidocaine; Middle Aged; Myo | 1978 |
Restricted lignocaine prophylaxis in acute myocardial infarction.
Topics: Acute Disease; Adult; Aged; Coronary Care Units; Humans; Lidocaine; Male; Middle Aged; Myocardial In | 1977 |
Electrocardiographic antecedent of primary ventricular fibrillation.
Topics: Electrocardiography; Humans; Lidocaine; Myocardial Infarction; Ventricular Fibrillation | 1977 |
[Lidocaine and the ventricular preexcitation syndrome].
Topics: Adult; Aged; Arrhythmias, Cardiac; Atrial Flutter; Drug Evaluation; Female; Humans; Lidocaine; Male; | 1977 |
Anesthetic management of prolonged Q-T interval syndrome.
Topics: Adolescent; Adult; Anesthesia, Endotracheal; Anesthesia, Local; Arrhythmias, Cardiac; Autonomic Nerv | 1977 |
Comparison of the effects of lignocaine and mexiletine on experimental ventricular arrhythmias.
Topics: Animals; Arrhythmias, Cardiac; Dogs; Lidocaine; Mexiletine; Propylamines; Tachycardia; Ventricular F | 1977 |
Ventricular fibrillation and acute myocardial infarction.
Topics: Acute Disease; Adult; Aged; Electric Countershock; Humans; Lidocaine; Middle Aged; Myocardial Infarc | 1977 |
Prevention of ventricular arrhythmias after myocardial infarction.
Topics: Disopyramide; Humans; Lidocaine; Mexiletine; Myocardial Infarction; Procainamide; Propranolol; Quini | 1977 |
Effect of lidocaine on the atrial fibrillation threshold.
Topics: Action Potentials; Animals; Atrial Fibrillation; Dogs; Heart; Lidocaine; Ventricular Fibrillation | 1977 |
Differing mechanisms for ventricular vulnerability during coronary artery occlusion and release.
Topics: Animals; Coronary Circulation; Coronary Disease; Dogs; Female; Heart; Lidocaine; Male; Phentolamine; | 1976 |
Disopyramide in a case of recurrent ventricular fibrillation.
Topics: Aged; Disopyramide; Humans; Lidocaine; Male; Pyridines; Recurrence; Ventricular Fibrillation | 1976 |
Lidocaine for VF.
Topics: Humans; Lidocaine; Ventricular Fibrillation | 1976 |
[Lidocaine therapy in the early phase of arrhythmia after acute myocardial infarct without influence on the fibrillatory threshold and on the spontaneous ventricular fibrillation of the heart].
Topics: Acute Disease; Animals; Arrhythmias, Cardiac; Dogs; Lidocaine; Myocardial Infarction; Time Factors; | 1976 |
[Ventricular fibrillation in "sick sinus syndrome"].
Topics: Aged; Bradycardia; Female; Humans; Lidocaine; Potassium; Sinoatrial Node; Ventricular Fibrillation | 1976 |
I.M. lidocaine injections for myocardial infarction.
Topics: Humans; Injections, Intramuscular; Lidocaine; Myocardial Infarction; Ventricular Fibrillation | 1975 |
The effects of practolol on the dysrhythmias complicating acute ischemic heart disease.
Topics: Aged; Arrhythmias, Cardiac; Bradycardia; Coronary Disease; Electrocardiography; Female; Humans; Lido | 1975 |
Pharmacological activity, metabolism, and pharmacokinetics of glycinexylidide.
Topics: Animals; Chromatography; Chromatography, Gas; Dose-Response Relationship, Drug; Electrocardiography; | 1975 |
Editorial: Doubts about lignocaine.
Topics: Coronary Care Units; Coronary Disease; Female; Humans; Lidocaine; Male; Myocardial Infarction; Ventr | 1975 |
[LETTER: Lidocaine per os. Its value in ventricular rhythm disorders].
Topics: Administration, Oral; Arrhythmias, Cardiac; Body Weight; Drug Tolerance; Heart Ventricles; Humans; L | 1975 |
Ventricular fibrillation threshold; its physiological and pharmacological importance.
Topics: Acidosis, Respiratory; Action Potentials; Aminophylline; Animals; Digitalis Glycosides; Dogs; Electr | 1975 |
[Letter: Recurring ventricular fibrillation].
Topics: Humans; Lidocaine; Recurrence; Ventricular Fibrillation | 1975 |
Practical guidelines for the use of lidocaine. Prevention and treatment of cardiac arrhythmias.
Topics: Arrhythmias, Cardiac; Humans; Injections, Intramuscular; Injections, Intravenous; Lidocaine; Tachyca | 1975 |
Ventricular fibrillation threshold and vulnerable period in the isolated perfused rat heart.
Topics: Animals; Blood Pressure; Electric Stimulation; Electrocardiography; Heart; In Vitro Techniques; Lido | 1975 |
Influence of the adrenal medulla on cardiac rhythm disturbances following acute coronary artery occlusions.
Topics: Adrenal Medulla; Animals; Arrhythmias, Cardiac; Cats; Coronary Disease; Epinephrine; Female; Lidocai | 1975 |
Percutaneous cannulation of the internal jugular vein for temporary endocardial pacing.
Topics: Adult; Aged; Cardiac Catheterization; Electrocardiography; Female; Fluoroscopy; Heart Diseases; Huma | 1975 |
The management of acute myocardial infarction.
Topics: Acute Disease; Arrhythmias, Cardiac; Catecholamines; Coronary Disease; Glycosides; Humans; Lidocaine | 1975 |
[Cardiovascular effects of glycerol-1-(2-diethyl-amino-ethylether)-3-(2-methoxyphenylether) in the anaesthetized cat (author's transl)].
Topics: Anesthetics, Local; Animals; Anti-Arrhythmia Agents; Blood Pressure; Cardiac Output; Cats; Diethylam | 1975 |
[Experiences with a mobile intensive care station (Kardiomobil) after 1 year's test operation in Zurich].
Topics: Arrhythmias, Cardiac; Coronary Care Units; Humans; Lidocaine; Mobile Health Units; Myocardial Infarc | 1976 |
Pindolol (Viscén) in persistent ventricular fibrillation. A case report.
Topics: Aged; Aortic Aneurysm; Electric Countershock; Female; Humans; Lidocaine; Pindolol; Resuscitation; Ta | 1976 |
Beneficial effect of lidocaine on ventricular electrical stability and spontaneous ventricular fibrillation during experimental myocardial infarction.
Topics: Animals; Dogs; Electrophysiology; Heart Ventricles; Lidocaine; Myocardial Infarction; Ventricular Fi | 1976 |
[Relation between the occurrence of malignant arrhythmia during acute myocardial ischemia and the weight of ischemic myocardium in goats].
Topics: Animals; Goats; Lidocaine; Male; Myocardial Ischemia; Myocardium; Tachycardia, Ventricular; Ventricu | 1992 |
Drug treatment of arrhythmias during cardiopulmonary resuscitation. A statement for the Advanced Life Support Working Party of the European Resuscitation Council.
Topics: Amiodarone; Animals; Arrhythmias, Cardiac; Atropine; Bretylium Compounds; Calcium; Cardiopulmonary R | 1992 |
[Comparison of antiarrhythmic effects of IHC-72 (an iodonium-72), lidocaine and verapamil].
Topics: Aconitine; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Edetic Acid; Female; Guinea Pigs; | 1992 |
[Reperfusion arrhythmias in acute myocardial infarction].
Topics: Aged; Angioplasty, Balloon, Coronary; Arrhythmias, Cardiac; Female; Humans; Lidocaine; Male; Middle | 1992 |
Cardiac sympathetic nervous activity during myocardial ischemia, reperfusion and ventricular fibrillation in the dog--effects of intravenous lidocaine.
Topics: Animals; Blood Pressure; Coronary Disease; Dogs; Electrocardiography; Female; Heart; Heart Conductio | 1992 |
Declining incidence of ventricular fibrillation in myocardial infarction. Implications for the prophylactic use of lidocaine.
Topics: Humans; Incidence; Lidocaine; Multivariate Analysis; Myocardial Infarction; Randomized Controlled Tr | 1992 |
Effects of lidocaine on relation between defibrillation threshold and upper limit of vulnerability in open-chest dogs.
Topics: Algorithms; Animals; Cardiac Pacing, Artificial; Dogs; Electric Countershock; Heart Conduction Syste | 1992 |
Stabilization of cardiac rhythm in subsequently fatal ventricular tachycardia and fibrillation by calcitonin gene-related peptide.
Topics: Amiodarone; Calcitonin Gene-Related Peptide; Electric Countershock; Electrocardiography, Ambulatory; | 1992 |
Torsades de pointes and ventricular fibrillation in a canine model of quinidine-induced QT prolongation.
Topics: Animals; Bretylium Tosylate; Cardiac Pacing, Artificial; Dogs; Female; Heart Conduction System; Isop | 1992 |
Chloroquine poisoning: ventricular fibrillation following 'trivial' overdose in a child.
Topics: Adolescent; Cardiopulmonary Resuscitation; Chloroquine; Drug Overdose; Electrocardiography; Gastric | 1992 |
Intracellular calcium during pacing-induced ventricular fibrillation. Effects of lidocaine.
Topics: Animals; Calcium; Cardiac Pacing, Artificial; Endocardium; Heart Conduction System; Lidocaine; Myoca | 1992 |
Successful defibrillation with near-simultaneous orthogonal discharges.
Topics: Bicarbonates; Electric Countershock; Epinephrine; Extracorporeal Circulation; Humans; Infusions, Int | 1991 |
Prevention of sudden coronary death.
Topics: Adrenergic beta-Antagonists; Analgesics; Animals; Anti-Anxiety Agents; Anti-Arrhythmia Agents; Benzo | 1991 |
Treatment with esmolol of ventricular fibrillation unresponsive to lidocaine and procainamide.
Topics: Adrenergic beta-Antagonists; Adult; Humans; Lidocaine; Male; Procainamide; Propanolamines; Ventricul | 1991 |
Implantable pharmacological defibrillator (AIPhD): preliminary investigations in animals.
Topics: Animals; Bretylium Tosylate; Electric Countershock; Electrocardiography; Equipment Design; Infusion | 1991 |
Effects of lidocaine on defibrillation threshold in the pig: evidence of anesthesia related increase.
Topics: Anesthesia; Animals; Electric Countershock; Electrocardiography; Halothane; Lidocaine; Pentobarbital | 1991 |
Effects of lidocaine and verapamil on defibrillation in humans.
Topics: Adult; Blood Pressure; Electric Countershock; Electrocardiography; Female; Heart; Heart Rate; Humans | 1991 |
The effect of lidocaine on myocardial ischemia with asanguinous reperfusion. An in vitro study.
Topics: Adenine Nucleotides; Animals; Coronary Circulation; Heart Arrest, Induced; In Vitro Techniques; Lact | 1991 |
[Pharmacotherapy of ventricular fibrillation. A prospective study in an emergency medical service].
Topics: Administration, Inhalation; Aged; Aged, 80 and over; Electric Countershock; Emergencies; Epinephrine | 1991 |
[Anti-arrhythmia therapy in emergencies--lidocaine versus ajmaline].
Topics: Ajmaline; Combined Modality Therapy; Electric Countershock; Electrocardiography; Emergencies; Heart | 1991 |
Bretylium tosylate versus lidocaine in experimental cardiac arrest.
Topics: Animals; Bretylium Tosylate; Disease Models, Animal; Dogs; Electric Countershock; Heart Arrest; Hemo | 1990 |
Myocardial preservation using lidocaine blood cardioplegia.
Topics: Aged; Body Temperature; Cardioplegic Solutions; Female; Humans; Lidocaine; Male; Middle Aged; Myocar | 1990 |
Potassium channel blockade: A mechanism for suppressing ventricular fibrillation.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Bethanidine; Bretylium Compounds; Cesium; Chickens; Decapo | 1986 |
Effects of metoprolol, alone and in combination with lidocaine, on ventricular fibrillation threshold: comparison with atenolol, propranolol, and pindolol.
Topics: Animals; Atenolol; Differential Threshold; Dogs; Drug Combinations; Isoproterenol; Lidocaine; Metopr | 1987 |
Interaction of metoprolol and lidocaine on the ventricular fibrillation threshold in the anesthetized dog.
Topics: Anesthesia; Animals; Dogs; Drug Synergism; Electrocardiography; Half-Life; Lidocaine; Metoprolol; Ti | 1988 |
Prophylactic lidocaine: concentrations in plasma and myocardial tissue and antifibrillatoric efficacy during early ischemia in dogs and pigs.
Topics: Animals; Anti-Arrhythmia Agents; Coronary Disease; Dogs; Hemodynamics; Lidocaine; Myocardium; Specie | 1988 |
Effects of antiarrhythmic drugs on the repetitive extrasystole threshold and the ventricular fibrillation threshold.
Topics: Animals; Anti-Arrhythmia Agents; Cardiac Complexes, Premature; Cardiac Pacing, Artificial; Disopyram | 1989 |
Evaluation of antiarrhythmic drugs on defibrillation energy requirements in dogs. Sodium channel block and action potential prolongation.
Topics: Acecainide; Action Potentials; Animals; Anti-Arrhythmia Agents; Cesium; Dogs; Electric Countershock; | 1989 |
Evaluation of cardiac vulnerability and antifibrillatory properties of anti-arrhythmic drugs.
Topics: Animals; Anti-Arrhythmia Agents; Cardiac Pacing, Artificial; Dogs; Electrocardiography; Heart; Heart | 1989 |
Lignocaine prophylaxis for reperfusion arrhythmias during treatment with streptokinase in acute myocardial infarction.
Topics: Humans; Lidocaine; Myocardial Infarction; Myocardial Reperfusion; Retrospective Studies; Streptokina | 1989 |
Ventricular arrhythmias following one-stage and two-stage coronary reperfusion: evidence for both reentry and enhanced automaticity.
Topics: Animals; Arrhythmias, Cardiac; Cardiac Complexes, Premature; Cardiac Pacing, Artificial; Coronary Ci | 1985 |
Acute induction of sustained ventricular tachycardia: a new porcine model.
Topics: Animals; Disease Models, Animal; Electric Stimulation; Electrocardiography; Heart; Heart Ventricles; | 1989 |
Myocardial infarction--coronary care.
Topics: Adrenergic beta-Antagonists; Animals; Coronary Care Units; Fibrinolytic Agents; Heart Rupture; Human | 1986 |
Prophylactic lidocaine in acute MI.
Topics: Drug Therapy, Combination; Humans; Lidocaine; Myocardial Infarction; Prognosis; Ventricular Fibrilla | 1989 |
Nursing management of the patient with acute myocardial infarction.
Topics: Angioplasty, Balloon; Coronary Care Units; Early Ambulation; Emergency Medical Services; Fibrinolyti | 1986 |
Short- and long-term therapy with tocainide for malignant ventricular tachyarrhythmias.
Topics: Adolescent; Adult; Aged; Anti-Arrhythmia Agents; Death, Sudden; Female; Heart Ventricles; Humans; Li | 1986 |
Mexiletine and tocainide: does response to one predict response to the other?
Topics: Adult; Aged; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Electric Stimulation; Electrocardiography | 1986 |
The effect of lidocaine and bretylium on the defibrillation threshold during cardiac arrest and cardiopulmonary resuscitation.
Topics: Animals; Bicarbonates; Bretylium Compounds; Carbon Dioxide; Dogs; Electric Countershock; Female; Hea | 1986 |
Efficacy of class Ib (lidocaine-like) antiarrhythmic agents for prevention of sustained ventricular tachycardia secondary to coronary artery disease.
Topics: Adult; Aged; Anti-Arrhythmia Agents; Coronary Disease; Electrophysiology; Female; Heart Ventricles; | 1987 |
Efficacy and tolerance of tocainide during long-term treatment of malignant ventricular arrhythmias.
Topics: Death, Sudden; Female; Follow-Up Studies; Humans; Kinetics; Lidocaine; Male; Middle Aged; Recurrence | 1987 |
Tocainide for drug-resistant sustained ventricular tachyarrhythmias.
Topics: Anti-Arrhythmia Agents; Cardiac Pacing, Artificial; Electrocardiography; Electrophysiology; Female; | 1988 |
Antifibrillatory effects of high dose bretylium and a lidocaine-bretylium combination during cardiopulmonary resuscitation.
Topics: Animals; Blood Pressure; Bretylium Compounds; Carbon Dioxide; Dogs; Drug Combinations; Electric Coun | 1988 |
[First pass effect of gallanilide in rats].
Topics: Animals; Anti-Arrhythmia Agents; Carbon Tetrachloride Poisoning; Chloramphenicol; Drug Incompatibili | 1988 |
Lignocaine in experimental myocardial infarction: failure to prevent neutrophil accumulation and ventricular fibrillation and to reduce infarct size.
Topics: Animals; Dogs; Female; Heart; Leukocyte Count; Lidocaine; Male; Myocardial Infarction; Myocardium; N | 1988 |
[Use of ethacizine and lidocaine to prevent ventricular fibrillation in acute myocardial infarction].
Topics: Adult; Aged; Anti-Arrhythmia Agents; Female; Humans; Lidocaine; Male; Middle Aged; Myocardial Infarc | 1988 |
Repetitive ventricular fibrillation preceded by both ST segment depression and elevation during acute myocardial ischemia.
Topics: Aged; Coronary Disease; Electric Countershock; Electrocardiography; Heparin; Humans; Lidocaine; Male | 1988 |
[Hyperkinetic ventricular arrhythmias in acute myocardial infarction: different etiopathogenetic mechanisms?].
Topics: Aged; Amiodarone; Electric Countershock; Electrocardiography; Female; Humans; Lidocaine; Male; Middl | 1987 |
Comparative investigations on the antiarrhythmic and electrophysiologic effects of class I-IV antiarrhythmic agents following acute coronary artery occlusion.
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Coronary Disease; Dogs; Female; Heart Conduct | 1987 |
Antiarrhythmic potency of naloxone determined by a screening test using the isolated ischaemic perfused rat heart preparation.
Topics: Animals; Anti-Arrhythmia Agents; Female; Lidocaine; Naloxone; Propranolol; Quinidine; Rats; Rats, In | 1987 |
[Preventive use of lidocaine in the prehospital phase of acute myocardial infarct].
Topics: Arrhythmias, Cardiac; Dose-Response Relationship, Drug; Electrocardiography; First Aid; Humans; Lido | 1987 |
Electrophysiologic, antiarrhythmic and hemodynamic effects of transcainide.
Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Fibrillation; Calci | 1987 |
Lidocaine causes a reversible, concentration-dependent increase in defibrillation energy requirements.
Topics: Animals; Dogs; Dose-Response Relationship, Drug; Electric Countershock; Lidocaine; Quinidine; Ventri | 1986 |
Coronary ligation-reperfusion arrhythmia models in anesthetized rats and isolated perfused rat hearts concentration-effect relationships of lidocaine.
Topics: Anesthesia; Animals; Arrhythmias, Cardiac; Coronary Circulation; Coronary Vessels; Dose-Response Rel | 1986 |
Ventricular fibrillation threshold in canine hearts with quinidine induced prolonged QT interval: effects of atrial pacing, isoproterenol, and lignocaine.
Topics: Animals; Cardiac Pacing, Artificial; Disease Models, Animal; Dogs; Female; Heart; Isoproterenol; Lid | 1986 |
Differential depressant and electrophysiologic cardiotoxicity of local anesthetics: an experimental study with special reference to lidocaine and bupivacaine.
Topics: Animals; Bupivacaine; Electrocardiography; Heart; Hemodynamics; Injections, Intra-Arterial; Lidocain | 1986 |
EMT-D fibrillation: more shocks for the future.
Topics: Allied Health Personnel; Electric Countershock; Emergency Medical Technicians; Humans; Lidocaine; Re | 1986 |
Immediate primary care of a suspected heart attack.
Topics: Combined Modality Therapy; Drug Therapy, Combination; Emergencies; Humans; Lidocaine; Myocardial Inf | 1986 |
The effect of oral cimetidine on total and unbound serum lidocaine concentrations in patients with suspected myocardial infarction.
Topics: Administration, Oral; Aged; Cimetidine; Drug Interactions; Humans; Lidocaine; Male; Middle Aged; Myo | 1987 |
Potential antiarrhythmic agents. II. Antiarrhythmic activity of basic N-(substituted phenyl and benzyl)dipeptides.
Topics: Aconitine; Animals; Anti-Arrhythmia Agents; Chemical Phenomena; Chemistry; Dipeptides; Guinea Pigs; | 1985 |
Effect of lidocaine and bretylium on energy requirements for transthoracic defibrillation: experimental studies.
Topics: Animals; Bretylium Compounds; Bretylium Tosylate; Chloralose; Dogs; Drug Interactions; Electric Coun | 1986 |
Treatment of perinfarction recurrent ventricular fibrillation by percutaneous pharmacological block of left stellate ganglion.
Topics: Anti-Arrhythmia Agents; Autonomic Nerve Block; Combined Modality Therapy; Electrocardiography; Human | 1985 |
Lidocaine and prevention of ventricular fibrillation complicating acute myocardial infarction.
Topics: Aged; Coronary Care Units; Critical Care; Humans; Lidocaine; Myocardial Infarction; Prognosis; Recur | 1985 |
[Ventricular fibrillation caused by myocardial infarction refractory to electric shock and xylocaine. Positive response to intravenous mexiletine].
Topics: Electric Countershock; Humans; Lidocaine; Male; Mexiletine; Middle Aged; Myocardial Infarction; Prop | 1985 |
Effects of verapamil and lidocaine in a canine model of sudden coronary death.
Topics: Animals; Arrhythmias, Cardiac; Death, Sudden; Dogs; Female; Heart Conduction System; Heart Rate; Lid | 1985 |
[Poisoning with detajmium bitartrate (tachmalcor)--a case report].
Topics: Adult; Ajmaline; Combined Modality Therapy; Dose-Response Relationship, Drug; Electrocardiography; F | 1985 |
The effect of lidocaine on lysophosphatidylcholine-induced cardiac arrhythmias and cellular disturbances.
Topics: Albumins; Animals; Arrhythmias, Cardiac; Cell Membrane; Cholesterol; Electrocardiography; Erythrocyt | 1985 |
Serum lidocaine levels during cardiopulmonary resuscitation after intravenous and endotracheal administration.
Topics: Absorption; Humans; Injections, Intravenous; Intubation, Intratracheal; Lidocaine; Resuscitation; Ve | 1985 |
Antifibrillatory effects of lidocaine and bretylium immediately postcardiopulmonary resuscitation.
Topics: Animals; Bretylium Compounds; Dogs; Dose-Response Relationship, Drug; Female; Lidocaine; Male; Resus | 1985 |
A cardiac antiarrhythmic screening test using the isolated ischaemic perfused rat heart preparation.
Topics: Animals; Anti-Arrhythmia Agents; Coronary Disease; Dose-Response Relationship, Drug; Drug Evaluation | 1985 |
[Favorable outcome after recurrent ventricular fibrillation in myocardial infarct].
Topics: Electric Countershock; Humans; Lidocaine; Male; Middle Aged; Myocardial Infarction; Recurrence; Vent | 1985 |
Effects of vagotomy and drugs on the ventricular fibrillation threshold of normal and ischemic hearts in the anesthetized rat.
Topics: Adenosine; Anesthesia; Animals; Aspirin; Blood Pressure; Bretylium Compounds; Coronary Disease; Hear | 1985 |
[Tachyarrhythmias caused by acute myocardial infarct].
Topics: Arrhythmias, Cardiac; Cardiac Complexes, Premature; Glucose; Humans; Insulin; Lidocaine; Myocardial | 1970 |
Incidence and management of ventricular arrhythmias after acute myocardial infarction.
Topics: Adult; Aged; Arrhythmias, Cardiac; Blood Pressure; Bundle-Branch Block; Cardiac Complexes, Premature | 1969 |
[Cardiac rhythm disorders. 2. Therapy].
Topics: Adrenergic alpha-Antagonists; Arrhythmia, Sinus; Arrhythmias, Cardiac; Atrial Fibrillation; Atrial F | 1971 |
Lidocaine (Xylocaine) as an anti-arrhythmic agent.
Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cardiac Complexes, Premature; Electrocardiography; Hea | 1971 |
Treatment of ventricular arrhythmias.
Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Heart Arrest; Heart Ventricles; Humans; Lidocaine; Myo | 1971 |
Prehospital care of acute myocardial infarction.
Topics: Cardiac Complexes, Premature; Death, Sudden; Electrocardiography; Emergency Medical Services; Health | 1972 |
Effect of lidocaine on the ventricular fibrillation threshold in the dog during acute ischemia and premature ventricular contractions.
Topics: Anesthesia, General; Animals; Cardiac Complexes, Premature; Coronary Disease; Dogs; Female; Infusion | 1972 |
Treatment of ventricular arrhythmias with mexiletine (Kö 1173).
Topics: Administration, Oral; Adult; Aged; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cardiac Complexes, | 1973 |
[Recurrent ventricular fibrillation due to renal potassium loss (author's transl)].
Topics: Cardiac Complexes, Premature; Cell Membrane Permeability; Coronary Angiography; Electrocardiography; | 1973 |
Use of plasma levels in evaluation of procainamide dosage.
Topics: Administration, Oral; Adult; Aged; Arrhythmias, Cardiac; Body Weight; Cardiac Complexes, Premature; | 1974 |
Comparison of ventricular parasystole with other dysrhythmias after acute myocardial infarction.
Topics: Arrhythmias, Cardiac; Cardiac Complexes, Premature; Electrocardiography; Female; Heart Arrest; Heart | 1974 |
[Arrhythmias in acute myocardial infarct].
Topics: Acidosis; Acute Disease; Arrhythmias, Cardiac; Aspartic Acid; Atrial Fibrillation; Atrial Flutter; B | 1973 |
[Therapy of arrhythmias].
Topics: Ajmaline; Arrhythmias, Cardiac; Atrial Fibrillation; Bradycardia; Caffeine; Cardiac Complexes, Prema | 1973 |
[Treatment of paroxysmal disorders of cardiac rhythm].
Topics: Acetanilides; Adrenergic beta-Antagonists; Ajmaline; Amino Alcohols; Arrhythmias, Cardiac; Atrial Fi | 1972 |
Cellular basis of cardiac dysrhythmias.
Topics: Action Potentials; Arrhythmias, Cardiac; Benzofurans; Bretylium Compounds; Cell Membrane Permeabilit | 1974 |
A mobile intensive-care unit in the management of myocardial infarction.
Topics: Adult; Aged; Ambulances; Electric Countershock; Electrocardiography; Female; Heart Arrest; Heart Mas | 1967 |
Prognosis after recovery from ventricular fibrillation complicating ischaemic heart-disease.
Topics: Anti-Bacterial Agents; Anticoagulants; Female; Follow-Up Studies; Furosemide; Glucose; Heart Arrest; | 1967 |
Lignocaine for arrythmias.
Topics: Cardiac Complexes, Premature; Humans; Lidocaine; Male; Middle Aged; Myocardial Infarction; Tachycard | 1968 |
Lignocaine for arrhythmias.
Topics: Arrhythmias, Cardiac; Humans; Lidocaine; Ventricular Fibrillation | 1968 |
Ventricular fibrillation complicating acute myocardial infarction.
Topics: Age Factors; Arrhythmias, Cardiac; Female; Follow-Up Studies; Heart Arrest; Humans; Lidocaine; Male; | 1968 |
Ethyl-3-ethoxycarbonyl-4-hydroxy-2H-1,2-benzothiazine-2-acetate-1,1-dioxide, a compound producing ventricular arrhythmias.
Topics: Animals; Arrhythmias, Cardiac; Atropine; Chlorisondamine; Dogs; Electrocardiography; Female; Lidocai | 1969 |
Lignocaine in the management of ventricular arrhythmias.
Topics: Adult; Arrhythmias, Cardiac; Cardiac Complexes, Premature; Coronary Disease; Digitalis Glycosides; H | 1969 |
Lidocaine as an antiarrhythmic Experience in 68 patients.
Topics: Adult; Aged; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Fibrillation; Atrial Flutter; Card | 1969 |
[Arrhythmias in myocardial infarct].
Topics: Aged; Arrhythmias, Cardiac; Atrial Fibrillation; Cardiac Complexes, Premature; Heart Block; Heart Ma | 1970 |
[Lidocaine in the therapy of ventricular arrhythmias].
Topics: Adolescent; Adult; Aged; Arrhythmias, Cardiac; Cardiac Complexes, Premature; Child; Female; Humans; | 1970 |
Impaired absorption and metabolism of oral lignocaine in patients undergoing laparoscopy.
Topics: Administration, Oral; Adult; Anesthesia, General; Female; Halothane; Humans; Laparoscopy; Lidocaine; | 1973 |
Cardiopulmonary resuscitation. II.
Topics: Acidosis; Aftercare; Bradycardia; Heart Arrest; Humans; Hyperkalemia; Hypokalemia; Isoproterenol; Li | 1969 |
[The pharmacological actions of butidrine. A comparative study of this new beta-adrenergic receptor antagonist and its four stereoisomers].
Topics: Amino Alcohols; Anesthetics, Local; Animals; Arteries; Birds; Blood Pressure; Calcium Chloride; Cate | 1968 |
A critical evaluation of three methods for the study of adrenergic beta-blocking and anti-arrhythmic agents.
Topics: Aconitum; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Bronchi; Chloroform; Constriction; | 1969 |
The reversal of experimental cardiac arrhythmias by indoramin (Wy 21901).
Topics: Amides; Anesthetics, Local; Animals; Arrhythmia, Sinus; Arrhythmias, Cardiac; Blood Pressure; Cats; | 1971 |
Characteristics and predictability of primary ventricular fibrillation.
Topics: Adult; Age Factors; Aged; Aspartate Aminotransferases; Electrocardiography; Female; Humans; L-Lactat | 1974 |
Low energy electrical defibrillation of human hearts during cardiac surgery.
Topics: Adult; Age Factors; Aged; Blood; Body Temperature; Carbon Dioxide; Cardiac Surgical Procedures; Card | 1974 |
Treatment of cardiac arrhythmias.
Topics: Arrhythmias, Cardiac; Atrial Fibrillation; Atrial Flutter; Digitalis; Digoxin; Electric Countershock | 1974 |
Heart failure and cardiac arrhythmias.
Topics: Arrhythmia, Sinus; Arrhythmias, Cardiac; Coronary Disease; Digoxin; Diuretics; Electroconvulsive The | 1974 |
[Contraindications to the use of digitalis in atrial fibrillation in the course of Wolff-Parkinson-White syndrome].
Topics: Aged; Atrial Fibrillation; Digoxin; Electrocardiography; Hemodynamics; Humans; Lidocaine; Male; Prac | 1974 |
Ventricular fibrillation in type B Wolff-Parkinson-White syndrome.
Topics: Adult; Female; Humans; Lidocaine; Pacemaker, Artificial; Practolol; Procainamide; Recurrence; Ventri | 1974 |
Gentamicin, tubocurarine, lignocaine and neuromuscular blockade. A case report.
Topics: Aortic Valve; Drug Interactions; Gentamicins; Heart Valve Prosthesis; Humans; Kidney Diseases; Lidoc | 1972 |
Quinidine syncope; report of a case successfully treated with lidocaine.
Topics: Adult; Atrial Fibrillation; Electrocardiography; Female; Humans; Lidocaine; Quinidine; Syncope; Tach | 1972 |
[Combination of xylocaine therapy and electric cardioversion in the management of ventricular fibrillation].
Topics: Adult; Aged; Electric Countershock; Female; Humans; Lidocaine; Male; Middle Aged; Ventricular Fibril | 1972 |
Acute sodium fluoride poisoning.
Topics: Acute Disease; Adult; Calcium; Diazepam; Diuretics; Electric Countershock; Esophageal Stenosis; Fluo | 1972 |
Cardiopulmonary resuscitation.
Topics: Arrhythmias, Cardiac; Bicarbonates; Calcium Chloride; Electric Countershock; Electrocardiography; Ep | 1973 |
Three therapeutic approaches in tachycardia.
Topics: Atrial Fibrillation; Atrial Flutter; Digitalis Glycosides; Electric Countershock; Heart Conduction S | 1973 |
Experimental acute myocardial infarction. Characterization and treatment of the malignant premature ventricular contraction.
Topics: Acute Disease; Animals; Arrhythmias, Cardiac; Atropine; Coronary Vessels; Dogs; Injections, Intraven | 1973 |
Cardiac arrhythmias. 6. Ventricular tachyarrhythmias. Clinical aspects.
Topics: Action Potentials; Bretylium Compounds; Digitalis Glycosides; Electric Countershock; Electrocardiogr | 1973 |
Experimental model for study of "sudden death" from ventricular fibrillation or asystole.
Topics: Angiocardiography; Animals; Aorta, Thoracic; Arrhythmias, Cardiac; Autopsy; Coronary Angiography; Co | 1973 |
Prophylactic uses of antiarrhythmic drugs in acute myocardial infarction.
Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atropine; Humans; Injections, Intravenous; Isoproteren | 1973 |
Lidocaine asystole.
Topics: Female; Heart Ventricles; Humans; Injections; Lidocaine; Middle Aged; Ventricular Fibrillation | 1973 |
Effect of current pulses delivered during the ventricular vulnerable period upon the ventricular fibrillation threshold.
Topics: Animals; Coronary Disease; Dogs; Electricity; Electrocardiography; Electrodes, Implanted; Female; Li | 1973 |
Experimental effects of anti-arrhythmic drugs on ventricular fibrillation thresholds altered by regional hyperkalemia.
Topics: Animals; Anti-Arrhythmia Agents; Bretylium Compounds; Dogs; Drug Evaluation, Preclinical; Electrocar | 1973 |
[1:1 Conduction in atrial flutter through lidocaine].
Topics: Adult; Atrial Flutter; Humans; Lidocaine; Male; Myocardial Infarction; Ventricular Fibrillation | 1973 |
Treatment of nontraumatic cardiac emergencies.
Topics: Adams-Stokes Syndrome; Arrhythmias, Cardiac; Atropine; Bradycardia; Electric Countershock; Emergency | 1974 |
The comparative antiarrhythmic actions of lidocaine and its quarternary derivative, methyl lidocaine.
Topics: Animals; Arrhythmias, Cardiac; Coronary Vessels; Digitalis Glycosides; Electrocardiography; Lidocain | 1974 |
Pathogenesis and prevention of sudden cardiac death.
Topics: Animals; Arteriosclerosis; Coronary Disease; Death, Sudden; Dogs; Heart; Humans; Lidocaine; Potassiu | 1974 |
Comprehensive treatment plan for the prevention of primary ventricular fibrillation in acute myocardial infarction.
Topics: Bretylium Compounds; Coronary Care Units; Drug Therapy, Combination; Humans; Injections, Intravenous | 1974 |
Paroxysmal familial ventricular fibrillation.
Topics: Child; Death, Sudden; Electrocardiography; Electrophysiology; Humans; Lidocaine; Male; Propranolol; | 1974 |
[Evaluation of some methods of treating cardiac arrhythmias].
Topics: Adams-Stokes Syndrome; Adult; Aged; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Fibrillatio | 1974 |
Letter: Effect of lidocaine on "gating" mechanism.
Topics: Animals; Disease Models, Animal; Dogs; Dose-Response Relationship, Drug; Heart; Heart Conduction Sys | 1974 |
Drugs in cardiopulmonary resuscitation.
Topics: Alkalies; Animals; Anti-Arrhythmia Agents; Bicarbonates; Dogs; Epinephrine; Humans; Lidocaine; Norep | 1966 |
[Value of xylocaine in coronary thrombosis].
Topics: Adult; Aged; Arrhythmias, Cardiac; Coronary Disease; Female; Humans; Lidocaine; Male; Middle Aged; M | 1969 |
Some cardiac effects of 1-allyl-2-benzyl-piperidine hc1, in vitro and in vivo.
Topics: Alkenes; Allyl Compounds; Animals; Anti-Arrhythmia Agents; Anura; Benzyl Compounds; Calcium Chloride | 1972 |
Investigations of the mode of action of a new antidysrhythmic drug, Kö 1173.
Topics: Action Potentials; Anesthetics, Local; Animals; Anti-Arrhythmia Agents; Anura; Bradycardia; Guinea P | 1972 |
Multiple episodes of ventricular fibrillation in acute myocardial infarction.
Topics: Acute Disease; Electric Countershock; Humans; Lidocaine; Male; Middle Aged; Myocardial Infarction; P | 1972 |
Treatment of ventricular tachycardia in an infant.
Topics: Adolescent; Adult; Age Factors; Angiocardiography; Cardiac Catheterization; Child; Child, Preschool; | 1972 |
Quantitative study of the effect of lidocaine on the threshold for ventricular fibrillation in the dog.
Topics: Animals; Anti-Arrhythmia Agents; Blood Gas Analysis; Blood Pressure; Dogs; Heart Ventricles; Lidocai | 1972 |
Blood levels of lignocaine after intramuscular administration to patients with proven or suspected acute myocardial infarction.
Topics: Adult; Aged; Aspartate Aminotransferases; Blood Pressure; Buttocks; Chromatography; Female; Heart Ra | 1972 |
Rational use of drugs for cardiac arrest and after cardiac resuscitation.
Topics: Adams-Stokes Syndrome; Arrhythmias, Cardiac; Atropine; Bicarbonates; Blood Circulation; Electric Cou | 1971 |
Arrhythmias in myocardial infarction.
Topics: Arrhythmias, Cardiac; Coronary Care Units; Electrocardiography; Humans; Lidocaine; Myocardial Infarc | 1971 |
[General anesthesia for a patient with past history of paroxysmal ventricular fibrillation].
Topics: Adams-Stokes Syndrome; Adult; Anesthesia, General; Cholecystectomy; Electrocardiography; Electrolyte | 1971 |
Effects of lignocaine, propranolol and bretylium on ventricular fibrillation threshold.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Bretylium Compounds; Dogs; Electrocardio | 1971 |
[Result report of a control by an apparatus of 208 myocardial infarct patients in an intensive care station. Preliminary report].
Topics: Adult; Aged; Arrhythmias, Cardiac; Atropine; Austria; Digitalis Glycosides; Electric Countershock; E | 1971 |
[Suicide attempt using ajmaline].
Topics: Adult; Ajmaline; Anuria; Bicarbonates; Bundle-Branch Block; Electrocardiography; Female; Humans; Iso | 1971 |
Acute coronary care.
Topics: Electric Countershock; Electrocardiography; Facility Design and Construction; Heart Massage; Humans; | 1968 |
Acute coronary care: a year's experience at Napier Hospital.
Topics: Anticoagulants; Arrhythmias, Cardiac; Atropine; Digoxin; Electric Countershock; Heart Arrest; Humans | 1968 |
Ventricular tachyarrhythmias and lignocaine prophylaxis in acute myocardial infarction. A clinical and therapeutic study.
Topics: Aged; Arrhythmias, Cardiac; Coronary Care Units; Electrocardiography; Female; Heart Failure; Humans; | 1970 |
Comparison of drugs used in management of arrhythmias developing after acute myocardial infarction.
Topics: Acetanilides; Arrhythmias, Cardiac; Humans; Lidocaine; Myocardial Infarction; Phenytoin; Procainamid | 1969 |
The effect of lignocaine on the stimulation threshold and conduction disturbances in patients treated with pacemaker.
Topics: Aged; Electric Stimulation; Female; Heart Block; Humans; Lidocaine; Male; Middle Aged; Pacemaker, Ar | 1969 |
[Arrhythmia as a cause of sudden death in cardiac infarction].
Topics: Aged; Death, Sudden; Electric Countershock; Female; Heart Arrest; Humans; Lidocaine; Male; Middle Ag | 1969 |
Pharmacology of intravenous local anesthetics.
Topics: Anesthetics, Local; Autonomic Nervous System; Cardiovascular System; Central Nervous System; Electro | 1969 |
[Ventricular fibrillation in acute myocardial infarct. Apropos of 7 cases with recovery].
Topics: Acute Disease; Aged; Electric Countershock; Female; Humans; Lidocaine; Male; Middle Aged; Myocardial | 1969 |
[The treatment of ventricular arrhythmias caused by myocardial infarct with xylocaine. Importance to recourse of electrosystolic pacing].
Topics: Adult; Aged; Ajmaline; Arrhythmias, Cardiac; Electric Countershock; Female; Humans; Lidocaine; Male; | 1969 |
Suppression of refractory recurrent ventricular tachycardia by transvenous rapid cardiac pacing and antiarrhythmic drugs. Report of seven cases.
Topics: Adult; Aged; Anti-Arrhythmia Agents; Atropine; Digitalis Glycosides; Digoxin; Electrocardiography; F | 1970 |
Bretylium tosylate in treatment of refractory ventricular arrhythmias complicating myocardial infarction.
Topics: Adult; Aged; Arrhythmias, Cardiac; Bradycardia; Bretylium Compounds; Electrocardiography; Female; Hu | 1970 |
A screening method for antiarrhythmic agents in the rat.
Topics: Animals; Anti-Arrhythmia Agents; Apnea; Bretylium Compounds; Chloroform; Dextroamphetamine; Guanethi | 1970 |
Antiarrhythmic drugs in the prevention of ventricular arrhythmias related to paired pacing.
Topics: Animals; Bretylium Compounds; Coronary Vessels; Dogs; Lidocaine; Myocardial Infarction; Pacemaker, A | 1970 |
[Lidocaine for arrhythmias. A case of ventricular flutter-fibrillation presumably provoked by lidocaine].
Topics: Aged; Atrial Fibrillation; Electric Countershock; Female; Humans; Injections, Intravenous; Lidocaine | 1970 |
[Therapy of the most important cardiac arrhythmias].
Topics: Arrhythmias, Cardiac; Atrial Fibrillation; Atrial Flutter; Bradycardia; Electric Countershock; Gluca | 1970 |
Cardiac arrhythmias during electroshock therapy: significance, prevention, and treatment.
Topics: Acidosis, Respiratory; Aged; Arrhythmias, Cardiac; Blood Gas Analysis; Coronary Disease; Electrocard | 1970 |
The comparative antiarrhythmic effects of mepivacaine and lignocaine.
Topics: Anesthesia, Local; Animals; Arrhythmias, Cardiac; Dogs; Electric Stimulation; Electrocardiography; H | 1970 |
Comparative effectiveness of lignocaine, quinidine, propranolol and procainamide as antifibrillatory agents.
Topics: Animals; Depression, Chemical; Electric Stimulation; Heart; Heart Rate; In Vitro Techniques; Lidocai | 1970 |
[Treatment of the most severe postoperative cardiac arrhythmias].
Topics: Aged; Arrhythmias, Cardiac; Bradycardia; Digitoxin; Electrocardiography; Female; Humans; Lidocaine; | 1970 |
Relative effectiveness of three antiarrhythmic agents in the treatment of ventricular arrhythmias in experimental acute myocardial ischemia.
Topics: Animals; Anti-Arrhythmia Agents; Dogs; Lidocaine; Male; Myocardial Infarction; Phenytoin; Procainami | 1971 |
Bretylium tosylate in the management of refractory ventricular fibrillation.
Topics: Adult; Age Factors; Aged; Angina Pectoris; Aortic Valve Insufficiency; Aortic Valve Stenosis; Bretyl | 1971 |
[Use of lidocaine in an unusual case of ventricular fibrillation].
Topics: Arrhythmias, Cardiac; Coronary Disease; Electrocardiography; Female; Humans; Lidocaine; Middle Aged; | 1971 |
Primary ventricular fibrillation complicating acute myocardial infarction.
Topics: Acute Disease; Adult; Age Factors; Aged; Arrhythmias, Cardiac; Electrocardiography; Female; Humans; | 1971 |
Quinidine-induced recurrent ventricular fibrillation: (quinidine syncope) treated with transvenous pacemaker.
Topics: Adult; Atrial Fibrillation; Atropine; Blood Cell Count; Chlorpromazine; Coumarins; Creatine Kinase; | 1971 |
Cardiac arrhythmias. I.
Topics: Arrhythmias, Cardiac; Atropine; Bradycardia; Cardiac Catheterization; Heart Block; Humans; Lidocaine | 1971 |
Quantitiative comparison of bretylium with other antifibrillatory drugs.
Topics: Animals; Anti-Arrhythmia Agents; Bretylium Compounds; Dogs; Electrocardiography; Guanethidine; Lidoc | 1968 |
Resuscitation from ventricular fibrillation. Drug therapy.
Topics: Animals; Bicarbonates; Blood Pressure; Bradycardia; Carbon Dioxide; Dogs; Electric Countershock; Epi | 1968 |
Management of persistently recurring ventricular fibrillation with propranolol hydrochloride.
Topics: Electric Countershock; Electrocardiography; Humans; Lidocaine; Male; Middle Aged; Myocardial Infarct | 1968 |
Fibrilation threshold curves and anti-arrhythmic drugs.
Topics: Animals; Anti-Arrhythmia Agents; Bretylium Compounds; Dogs; Electric Stimulation; Hydroxyzine; Imida | 1968 |
Evaluation of antifibrillatory agents and catecholamines by a physiologic method.
Topics: Animals; Catecholamines; Dogs; Epinephrine; Heart; Heart Ventricles; Lidocaine; Norepinephrine; Prop | 1968 |
Ventricular fibrillation threshold (VFRT) in experimental coronary occlusion: comparative studies on the effect of G-I-K solution and some new antiarrhythmic agents.
Topics: Animals; Anti-Arrhythmia Agents; Dogs; Electrocardiography; Glucose; Hematocrit; Hydrogen-Ion Concen | 1968 |
Case report: successful treatment of ventricular tachycardia associated with thioridazine (Mellaril).
Topics: Arrhythmias, Cardiac; Aspartate Aminotransferases; Electric Countershock; Electrocardiography; Human | 1969 |
[Lidocaine as an anti-arrhythmic drug].
Topics: Anti-Arrhythmia Agents; Emergencies; Female; Humans; Lidocaine; Middle Aged; Pacemaker, Artificial; | 1969 |
Treatment of arrhythmias in myocardial infarction.
Topics: Arrhythmias, Cardiac; Atropine; Bradycardia; Digitalis Glycosides; Electric Countershock; Electrocar | 1969 |
Direct current shock and lidocaine in the treatment of digitalis-induced ventricular tachycardia.
Topics: Animals; Digitalis Glycosides; Dogs; Electric Countershock; Electrocardiography; Lidocaine; Ouabain; | 1966 |
Recurrent ventricular fibrillation treated by multiple countershocks.
Topics: Coronary Disease; Dextrans; Electric Countershock; Electrocardiography; Humans; Lidocaine; Male; Mid | 1966 |
Ventricular tachycardia. Control by intermittent, intravenous administration of lidocaine hydrochloride.
Topics: Adult; Electric Countershock; Electrocardiography; Female; Heart Ventricles; Humans; Injections, Int | 1966 |