Page last updated: 2024-10-28

lidocaine and Uterine Hemorrhage

lidocaine has been researched along with Uterine Hemorrhage in 22 studies

Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.

Uterine Hemorrhage: Bleeding from blood vessels in the UTERUS, sometimes manifested as vaginal bleeding.

Research Excerpts

ExcerptRelevanceReference
"The results of our study showed that lidocaine puffs provided the best pain relief than the other analgesics used."9.20Effect of paracetamol, dexketoprofen trometamol, lidocaine spray, pethidine & diclofenac sodium application for pain relief during fractional curettage: A randomized controlled trial. ( Acmaz, G; Aksoy, H; Başer, M; Bayraktar, E; Müderris, İİ; Yilmaz, MO, 2015)
"The results of our study showed that lidocaine puffs provided the best pain relief than the other analgesics used."5.20Effect of paracetamol, dexketoprofen trometamol, lidocaine spray, pethidine & diclofenac sodium application for pain relief during fractional curettage: A randomized controlled trial. ( Acmaz, G; Aksoy, H; Başer, M; Bayraktar, E; Müderris, İİ; Yilmaz, MO, 2015)
"Lidocaine spray was the most effective medication for reducing pain during OEB (P-score = 0."5.01Medications for pain relief in outpatient endometrial sampling or biopsy: a systematic review and network meta-analysis. ( Abbas, AM; Abdallah, KM; Abdelbaky, WH; Ahmed, MAM; Badawy, MA; El-Naser Abd El-Gaber Ali, A; El-Rasheedy, MI; Elktatny, HH; Khodry, MM; Mohammed, AE; Raslan, OK; Samy, A, 2019)
"Of the 305 women approached, 300 women were randomised into the study."2.71Randomised comparison of distension media for outpatient hysteroscopy. ( Davidson, A; Habiba, M; Shankar, M; Taub, N, 2004)
"Cesarean scar pregnancy and cervical pregnancy are unrelated forms of pathological pregnancies carrying significant diagnostic and treatment challenges, with a wide range of treatment effectiveness and complication rates ranging from 10% to 62%."1.43A new minimally invasive treatment for cesarean scar pregnancy and cervical pregnancy. ( Bennett, TA; Foley, C; Kaelin Agten, A; Monteagudo, A; Ramos, J; Timor-Tritsch, IE, 2016)
"However, studies of hemorrhagic shock in nonpregnant animals may not be applicable to less severe hemorrhage in pregnant animals."1.28Epidural anesthesia worsens uterine blood flow and fetal oxygenation during hemorrhage in gravid ewes. ( Chatterjee, P; Chestnut, DH; DeBruyn, CS; Sipes, SL; Thompson, CS; Vincent, RD, 1992)

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19907 (31.82)18.7374
1990's5 (22.73)18.2507
2000's6 (27.27)29.6817
2010's4 (18.18)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Abbas, AM1
Samy, A1
El-Naser Abd El-Gaber Ali, A1
Khodry, MM1
Ahmed, MAM1
El-Rasheedy, MI1
Abdallah, KM1
Mohammed, AE1
Abdelbaky, WH1
Raslan, OK1
Badawy, MA1
Elktatny, HH1
Mittal, P1
Goyal, M1
Acmaz, G1
Bayraktar, E1
Aksoy, H1
Başer, M1
Yilmaz, MO1
Müderris, İİ1
Timor-Tritsch, IE1
Monteagudo, A1
Bennett, TA1
Foley, C1
Ramos, J1
Kaelin Agten, A1
Titapant, V1
Chawanpaiboon, S1
Boonpektrakul, K1
SANDMIRE, HF2
AUSTIN, SD2
Shankar, M1
Davidson, A1
Taub, N1
Habiba, M1
Rattanachaiyanont, M1
Leerasiri, P1
Indhavivadhana, S1
Hui, SK1
Lee, L1
Ong, C1
Yu, V1
Ho, LC1
McLucas, B1
McGill, J1
Finikiotis, G1
Lau, WC1
Lo, WK1
Tam, WH1
Yuen, PM1
Kozman, E1
Collins, P1
Howard, A1
Akanmu, T1
Gibbs, A1
Frazer, M1
van Trotsenburg, M1
Wieser, F1
Nagele, F1
Broadbent, JA1
Hill, NC1
Molnár, BG1
Rolfe, KJ1
Magos, AL1
Vincent, RD1
Chestnut, DH1
Sipes, SL1
DeBruyn, CS1
Chatterjee, P1
Thompson, CS1
Dunn, SR1
Walker, JS1
Aston, DL1
Cripps, D1
Habersetzer, B1
Raudrant, D1
Broussard, P1
Hasson, HM1
Alfredsson, J1
Higier, J1
Krajewski, J1
Turowski, J1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
[NCT01993589]144 participants (Actual)Interventional2012-11-30Completed
Double Blind, Randomized, Prospective Trial of Impact of Pain Scores on Intrauterine Lidocaine vs Normal Saline Infusion Before IUD Placement.[NCT01311102]Phase 440 participants (Actual)Interventional2008-07-31Completed
A Prospective Randomized Study Comparing Different Types of Local Anesthesia in Outpatient Procedural Hysteroscopy[NCT05967936]242 participants (Anticipated)Interventional2023-09-01Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Pain During IUD Placement

"IUD was inserted following the manufacturer's instructions, and a pain score was immediately obtained. Pain was scored on 0-9 scale; with 0 being no pain and 9 being worst pain in life." (NCT01311102)
Timeframe: Immediately after IUD placement

Interventionunits on a scale of 0-9 (Mean)
Lidocaine2.95
Normal Saline3.68

Pain During Tenaculum Placement

"Pain score on 0-9 scale for tenaculum placement (without anesthesia); with 0 being no pain and 9 being worst pain in life. Taken to adjust for different pain thresholds among subjects" (NCT01311102)
Timeframe: Immediately following tenaculum placement

Interventionunits on a scale of 0-9 (Mean)
Lidocaine2.20
Normal Saline2.70

Pain Measurement During Liquid Infusion/Sounding

"After liquid infused into three parts of the endometrial cavity: in the lower one third, the middle, and at the top of the cavity. Pain was scored on a 0-9 scale; with 0 being no pain and 9 being worst pain in life." (NCT01311102)
Timeframe: Recorded at the end of the infusion

Interventionunits on a scale of 0-9 (Mean)
Lidocaine2.50
Normal Saline3.39

Pain Scores During Overall IUD Placement

"Pain score on 0-9 scale obtained just before the patient left the examination room; with 0 being no pain and 9 being worst pain in life." (NCT01311102)
Timeframe: Before patient left the examination room at conclusion of procedure

Interventionunits on a scale of 0-9 (Mean)
Lidocaine2.12
Normal Saline1.73

Reviews

2 reviews available for lidocaine and Uterine Hemorrhage

ArticleYear
Medications for pain relief in outpatient endometrial sampling or biopsy: a systematic review and network meta-analysis.
    Fertility and sterility, 2019, Volume: 112, Issue:1

    Topics: Ambulatory Care; Analgesics; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Biopsy; En

2019
Pure cutting current for loop excision of squamous intraepithelial lesions.
    The Journal of reproductive medicine, 1994, Volume: 39, Issue:5

    Topics: Carcinoma, Squamous Cell; Colposcopy; Drug Combinations; Electrosurgery; Epinephrine; Female; Follow

1994

Trials

8 trials available for lidocaine and Uterine Hemorrhage

ArticleYear
Effect of paracetamol, dexketoprofen trometamol, lidocaine spray, pethidine & diclofenac sodium application for pain relief during fractional curettage: A randomized controlled trial.
    The Indian journal of medical research, 2015, Volume: 142, Issue:4

    Topics: Acetaminophen; Adult; Aged; Analgesia; Curettage; Diclofenac; Female; Gynecologic Surgical Procedure

2015
Double-blind randomized comparison of xylocaine and saline in paracervical block for diagnostic fractional curettage.
    Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2003, Volume: 86, Issue:2

    Topics: Adult; Anesthesia, Conduction; Chi-Square Distribution; Dilatation and Curettage; Double-Blind Metho

2003
Randomised comparison of distension media for outpatient hysteroscopy.
    BJOG : an international journal of obstetrics and gynaecology, 2004, Volume: 111, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Ambulatory Care; Anesthetics, Local; Carbon Dioxide; Dilatation; Fem

2004
Effectiveness of intrauterine anesthesia for pain relief during fractional curettage.
    Obstetrics and gynecology, 2005, Volume: 106, Issue:3

    Topics: Administration, Intravaginal; Adult; Anesthesia, Obstetrical; Anesthetics, Local; Dilatation and Cur

2005
Intrauterine lignocaine as an anaesthetic during endometrial sampling: a randomised double-blind controlled trial.
    BJOG : an international journal of obstetrics and gynaecology, 2006, Volume: 113, Issue:1

    Topics: Adult; Anesthetics, Local; Double-Blind Method; Endometrium; Female; Gynecologic Surgical Procedures

2006
Paracervical anaesthesia in outpatient hysteroscopy: a randomised double-blind placebo-controlled trial.
    British journal of obstetrics and gynaecology, 1999, Volume: 106, Issue:4

    Topics: Adult; Ambulatory Care; Anesthesia, Local; Anesthetics, Local; Biopsy; Blood Pressure; Cervix Uteri;

1999
The effect of an intrauterine application of two percent lignocaine gel on pain perception during Vabra endometrial sampling: a randomised double-blind, placebo-controlled trial.
    BJOG : an international journal of obstetrics and gynaecology, 2001, Volume: 108, Issue:1

    Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Anesthetics, Local; Biopsy; Double-Blind Me

2001
Randomized placebo controlled trial to assess the role of intracervical lignocaine in outpatient hysteroscopy.
    British journal of obstetrics and gynaecology, 1992, Volume: 99, Issue:9

    Topics: Adult; Ambulatory Care; Anesthesia, Local; Double-Blind Method; Female; Humans; Hysteroscopy; Lidoca

1992

Other Studies

12 other studies available for lidocaine and Uterine Hemorrhage

ArticleYear
Pain relief during minor procedures: a challenge for gynaecologists.
    The Indian journal of medical research, 2015, Volume: 142, Issue:4

    Topics: Anesthesia, Obstetrical; Anti-Inflammatory Agents, Non-Steroidal; Biopsy; Endometrium; Female; Human

2015
A new minimally invasive treatment for cesarean scar pregnancy and cervical pregnancy.
    American journal of obstetrics and gynecology, 2016, Volume: 215, Issue:3

    Topics: Anesthetics, Local; Catheterization; Catheters; Cesarean Section; Cicatrix; Female; Humans; Lidocain

2016
CURETTAGE AS A OFFICE PROCEDURE.
    Obstetrics and gynecology, 1964, Volume: 24

    Topics: Curettage; Equipment and Supplies; Female; Humans; Lidocaine; Office Management; Postoperative Compl

1964
Side-effects and complications of outpatient hysteroscopy.
    The Australian & New Zealand journal of obstetrics & gynaecology, 1993, Volume: 33, Issue:1

    Topics: Ambulatory Care; Anesthesia, Local; Epinephrine; Female; Humans; Hysteroscopy; Lidocaine; Nerve Bloc

1993
Diagnostic hysteroscopy for the investigation of abnormal uterine bleeding in premenopausal patients.
    Contributions to gynecology and obstetrics, 2000, Volume: 20

    Topics: Adolescent; Adult; Age Factors; Ambulatory Care; Anesthetics, Local; Female; Humans; Hysteroscopy; L

2000
Epidural anesthesia worsens uterine blood flow and fetal oxygenation during hemorrhage in gravid ewes.
    Anesthesiology, 1992, Volume: 76, Issue:5

    Topics: Anesthesia, Epidural; Anesthesia, Obstetrical; Animals; Bupivacaine; Carbon Dioxide; Epinephrine; Fe

1992
Effect of anaesthetic technique on blood loss in termination of pregnancy.
    British journal of anaesthesia, 1973, Volume: 45, Issue:6

    Topics: Abortion, Induced; Adult; Anesthesia, Conduction; Anesthesia, General; Cervix Uteri; Diazepam; Femal

1973
[Uterine evacuation under local anesthesia by paracervical block with xylocaine (apropos of 40 cases)].
    Journal de medecine de Lyon, 1972, Nov-05, Volume: 53, Issue:236

    Topics: Anesthesia, Local; Curettage; Female; Humans; Lidocaine; Methods; Pregnancy; Uterine Hemorrhage; Ute

1972
Curettage as an office procedure.
    American journal of obstetrics and gynecology, 1974, May-01, Volume: 119, Issue:1

    Topics: Abortion, Therapeutic; Anesthesia, Local; Costs and Cost Analysis; Curettage; Dilatation; Drug Hyper

1974
Clinical applications of the wing sound device.
    Obstetrics and gynecology, 1974, Volume: 43, Issue:4

    Topics: Adult; Biopsy; Cervix Uteri; Endometrium; Female; Follow-Up Studies; Genital Diseases, Female; Gynec

1974
[Paracervical blockade in primary exeresis].
    Lakartidningen, 1972, Jul-12, Volume: 69, Issue:29

    Topics: Abortion, Legal; Adolescent; Adult; Anesthesia, Conduction; Anesthesia, Obstetrical; Cervix Uteri; D

1972
[Analysis of blood loss in artificial termination of pregnancy under local anesthesia].
    Wiadomosci lekarskie (Warsaw, Poland : 1960), 1970, Aug-01, Volume: 23, Issue:15

    Topics: Abortion, Therapeutic; Adolescent; Adult; Anesthesia, Local; Anesthesia, Obstetrical; Female; Hemogl

1970