Page last updated: 2024-10-28

lidocaine and Uterine Cervical Neoplasms

lidocaine has been researched along with Uterine Cervical Neoplasms in 15 studies

Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.

Uterine Cervical Neoplasms: Tumors or cancer of the UTERINE CERVIX.

Research Excerpts

ExcerptRelevanceReference
"Lidocaine spray is an effective and practical alternative measure for reducing pain associated with electrical excision of the cervix during LEEP."9.17Lidocaine spray compared with submucosal injection for reducing pain during loop electrosurgical excision procedure: a randomized controlled trial. ( Charoenkwan, K; Vanichtantikul, A, 2013)
"Our study evaluated whether buffering reduces pain from lidocaine injection for loop electrosurgical excisional procedures (LEEPs) of the cervix when compared to unbuffered lidocaine."5.19A randomized trial of buffered versus nonbuffered lidocaine with epinephrine for cervical loop excision. ( Ioffe, Y; Kizer, NT; Massad, LS; Peipert, JF; Zhao, Q, 2014)
"Lidocaine spray is an effective and practical alternative measure for reducing pain associated with electrical excision of the cervix during LEEP."5.17Lidocaine spray compared with submucosal injection for reducing pain during loop electrosurgical excision procedure: a randomized controlled trial. ( Charoenkwan, K; Vanichtantikul, A, 2013)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19901 (6.67)18.7374
1990's7 (46.67)18.2507
2000's3 (20.00)29.6817
2010's4 (26.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kizer, NT1
Zhao, Q1
Peipert, JF1
Ioffe, Y1
Massad, LS1
Vanichtantikul, A1
Charoenkwan, K1
Öz, M1
Korkmaz, E1
Cetinkaya, N1
Baş, S1
Özdal, B1
Meydanl, MM1
Güngör, T1
Wang, HL1
Yan, HD1
Liu, YY1
Sun, BZ1
Huang, R1
Wang, XS1
Lei, WF1
Gaus, P1
Eich, C1
Hildebrandt, J1
Mercadante, S1
Villari, P1
Ferrera, P1
Arcuri, E1
McLucas, B1
McGill, J1
McLachlin, CM1
Devine, P1
Muto, M1
Genest, DR1
Chen, RJ1
Chow, SN1
Huang, SC1
Chen, HC1
Leung, SW1
Wang, CJ1
Sun, LM1
Fang, FM1
Huang, EY1
Wang, SJ1
Yang, CW1
Yeo, SN1
Chong, JL1
Due, J1
Ebert, A1
Goetze, B1
Sopracordevole, F1
Campagnutta, E1
Scarabelli, C1
Sarkar, PK1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Buffered Lidocaine for Paracervical Block to Decrease Injection Pain During First Trimester Uterine Aspirations[NCT03107754]Phase 498 participants (Actual)Interventional2017-05-15Completed
Lidocaine Spray Compared With Submucosal Injection in Reducing Pain During Loop Electrosurgical Excision Procedure: a Randomized Controlled Trial[NCT01505920]Phase 3101 participants (Actual)Interventional2011-09-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Injection Pain

For the primary outcome, pain immediately after paracervical block injection was measured by a scale. The scale used was the 100-mm visual analog scale. The minimum score was 0 and the maximum score was 100. Higher numbers indicate worse pain. (NCT03107754)
Timeframe: Immediately after injection of the paracervical block

Interventionunits on a scale (Median)
Standard Paracervical Block44.5
Buffered Lidocaine Paracervical Block30

Pain After Speculum Placement, Cervical Dilation, and Aspiration

Pain scores were measured at multiple points throughout the procedure. Pain scores were measured using a 100 mm visual analog scale with 0 being no pain and 100 being the worst pain ever. (NCT03107754)
Timeframe: Immediately after speculum placement, cervical dilation, uterine aspiration

,
Interventionunits on a scale (Median)
After insertion of speculumAfter cervical dilationAfter uterine aspiration
Buffered Lidocaine Paracervical Block175569
Standard Paracervical Block1360.0667.5

Reviews

1 review available for lidocaine and Uterine Cervical Neoplasms

ArticleYear
Pure cutting current for loop excision of squamous intraepithelial lesions.
    The Journal of reproductive medicine, 1994, Volume: 39, Issue:5

    Topics: Carcinoma, Squamous Cell; Colposcopy; Drug Combinations; Electrosurgery; Epinephrine; Female; Follow

1994

Trials

8 trials available for lidocaine and Uterine Cervical Neoplasms

ArticleYear
A randomized trial of buffered versus nonbuffered lidocaine with epinephrine for cervical loop excision.
    Journal of lower genital tract disease, 2014, Volume: 18, Issue:1

    Topics: Adolescent; Adult; Anesthetics, Local; Buffers; Double-Blind Method; Electrosurgery; Epinephrine; Fe

2014
Lidocaine spray compared with submucosal injection for reducing pain during loop electrosurgical excision procedure: a randomized controlled trial.
    Obstetrics and gynecology, 2013, Volume: 122, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Analgesia; Anesthetics, Local; Electrosurgery; Female; Humans; Injec

2013
Comparison of Topical Lidocaine Spray With Placebo for Pain Relief in Colposcopic Procedures: A Randomized, Placebo-Controlled, Double-Blind Study.
    Journal of lower genital tract disease, 2015, Volume: 19, Issue:3

    Topics: Adult; Anesthetics, Local; Colposcopy; Curettage; Double-Blind Method; Female; Hospitals; Humans; Li

2015
Intraoperative intravenous lidocaine exerts a protective effect on cell-mediated immunity in patients undergoing radical hysterectomy.
    Molecular medicine reports, 2015, Volume: 12, Issue:5

    Topics: Adult; Aged; Anesthetics, Local; Apoptosis; Cell Proliferation; Cells, Cultured; Female; HMGB1 Prote

2015
A study on the usefulness of local anaesthesia for the laser vaporization of conizations in the uterine cervix.
    Annals of the Academy of Medicine, Singapore, 1994, Volume: 23, Issue:1

    Topics: Adult; Anesthesia, Local; Female; Humans; Laser Therapy; Lidocaine; Pain; Patient Acceptance of Heal

1994
Local vaginal anesthesia during high-dose-rate intracavitary brachytherapy for cervical cancer.
    International journal of radiation oncology, biology, physics, 1998, Oct-01, Volume: 42, Issue:3

    Topics: Anesthesia, Local; Anesthetics, Local; Brachytherapy; Female; Humans; Lidocaine; Middle Aged; Prospe

1998
[Local anesthesia in cervix biopsy].
    Minerva ginecologica, 1992, Volume: 44, Issue:6

    Topics: Anesthesia, Local; Biopsy; Cervix Uteri; Diagnosis, Differential; Female; Humans; Lidocaine; Uterine

1992
Topical anaesthesia with lignocaine-prilocaine cream (EMLA) for carbon dioxide treatment to the cervix--a pilot study.
    The British journal of clinical practice, 1990, Volume: 44, Issue:9

    Topics: Adult; Anesthesia, Local; Anesthetics, Local; Drug Combinations; Female; Humans; Laser Therapy; Lido

1990

Other Studies

6 other studies available for lidocaine and Uterine Cervical Neoplasms

ArticleYear
[Delayed occurrence of subdural malposition of epidural catheter].
    Der Anaesthesist, 2002, Volume: 51, Issue:11

    Topics: Adult; Anesthesia, Epidural; Anesthetics, Local; Catheterization; Cranial Nerves; Female; Humans; Li

2002
Local anesthetic switching for intrathecal tachyphylaxis in cancer patients with pain.
    Anesthesia and analgesia, 2003, Volume: 97, Issue:1

    Topics: Adult; Anesthetics, Local; Bupivacaine; Carcinoma, Small Cell; Endometrial Neoplasms; Female; Humans

2003
Pseudoinvasion of vascular spaces: report of an artifact caused by cervical lidocaine injection prior to loop diathermy.
    Human pathology, 1994, Volume: 25, Issue:2

    Topics: Adult; Anesthesia, Local; Artifacts; Blood Vessels; Cervix Uteri; Diathermy; Female; Humans; Injecti

1994
A case report on the treatment of intractable anal pain from metastatic carcinoma of the cervix.
    Annals of the Academy of Medicine, Singapore, 2001, Volume: 30, Issue:6

    Topics: Adult; Anal Canal; Anesthetics, Local; Autonomic Nerve Block; Carcinoma; Female; Ganglia, Autonomic;

2001
[Easing of a painful death].
    Nederlands tijdschrift voor geneeskunde, 1977, Dec-31, Volume: 121, Issue:53

    Topics: Adult; Aged; Celiac Plexus; Ethanol; Female; Humans; Injections, Spinal; Lidocaine; Lung Neoplasms;

1977
[Use of xylocaine in placing afterloading applicators in the gynecologic area--a simplified and analgesic method].
    Zentralblatt fur Gynakologie, 1992, Volume: 114, Issue:12

    Topics: Anesthesia, Local; Brachytherapy; Female; Humans; Lidocaine; Pain Measurement; Uterine Cervical Neop

1992