lidocaine has been researched along with Urination Disorders in 17 studies
Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.
Urination Disorders: Abnormalities in the process of URINE voiding, including bladder control, frequency of URINATION, as well as the volume and composition of URINE.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Lidocaine EMDA is superior to alkalized lidocaine in that it allows for a greater distention of the bladder for a longer period of time but does not eliminate the pain of bladder distention." | 5.11 | Pilot study of the feasibility of in-office bladder distention using electromotive drug adminstration (EMDA). ( Azevedo, K; Payne, CK; Rose, AE, 2005) |
| "Phenazopyridine has been associated with methemoglobinemia in patients who have received an overdose, have decreased renal function, or are discovered to be unusually susceptible to the drug (ie, they may have an undetected NADH methemoglobin reductase deficiency)." | 3.68 | Acquired methemoglobinemia from multiple oxidants. ( Bailey, MK; Baker, JD; Conroy, JM; Dorman, BH; Martin, WJ, 1993) |
| "To evaluate the effect of placement of urethral catheter combined with lidocaine on urethral irritation caused by postoperative indwelling catheters." | 2.77 | [Effect of painless urethral catheterization combined with lidocaine on urethral irritation]. ( Bian, J; Li, F; Liu, C; Xue, K; Yang, J; Zhong, Q; Zhou, Q, 2012) |
| " No patients were admitted to hospital due to adverse events associated with hydrodistension." | 2.74 | Hydrodistension under local anesthesia for patients with suspected painful bladder syndrome/interstitial cystitis: safety, diagnostic potential and therapeutic efficacy. ( Aihara, K; Fujimoto, K; Hirao, Y; Hirayama, A; Tanaka, N; Yoshida, K, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (47.06) | 18.7374 |
| 1990's | 3 (17.65) | 18.2507 |
| 2000's | 3 (17.65) | 29.6817 |
| 2010's | 3 (17.65) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Breebaart, MB | 2 |
| Teune, A | 1 |
| Sermeus, LA | 1 |
| Vercauteren, MP | 2 |
| Mazzo, A | 1 |
| Pecci, GL | 1 |
| Fumincelli, L | 1 |
| Neves, RC | 1 |
| Dos Santos, RC | 1 |
| Cassini, MF | 1 |
| Tucci, S | 1 |
| Aihara, K | 1 |
| Hirayama, A | 1 |
| Tanaka, N | 1 |
| Fujimoto, K | 1 |
| Yoshida, K | 1 |
| Hirao, Y | 1 |
| Yang, J | 1 |
| Zhou, Q | 1 |
| Liu, C | 1 |
| Li, F | 1 |
| Bian, J | 1 |
| Zhong, Q | 1 |
| Xue, K | 1 |
| Hoffmann, VL | 1 |
| Adriaensen, HA | 1 |
| Rose, AE | 1 |
| Payne, CK | 1 |
| Azevedo, K | 1 |
| Reuther, K | 1 |
| Aagaard, J | 1 |
| Jensen, KS | 1 |
| Conroy, JM | 1 |
| Baker, JD | 1 |
| Martin, WJ | 1 |
| Bailey, MK | 1 |
| Dorman, BH | 1 |
| Loo, CC | 1 |
| Irestedt, L | 1 |
| Moir, DD | 1 |
| Slater, PJ | 1 |
| Thorburn, J | 1 |
| McLaren, R | 1 |
| Moodie, J | 1 |
| Curelaru, I | 1 |
| Bridenbaugh, LD | 1 |
| Lanz, E | 1 |
| Grab, BM | 1 |
| Morikawa, K | 1 |
| Yamauchi, T | 1 |
| Kato, H | 1 |
| Ito, Y | 1 |
| Dawkins, CJ | 1 |
| de Morsier, G | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Influence of Spinal or Intravenous Dexmedetomidine on Spinal Anesthesia With Chloroprocaine and Bladder Function in Day-case Surgery. A Double Blind Randomized Study.[NCT02282319] | Phase 4 | 150 participants (Anticipated) | Interventional | 2014-10-31 | Completed | ||
| Use of Preemptive Pudendal Nerve Block Prior to Hydrodistension for the Treatment of Interstitial Cystitis/Painful Bladder Syndrome (IC/PBS): a Prospective, Double-blinded, Randomized Control Trial[NCT02517996] | 18 participants (Actual) | Interventional | 2015-02-28 | Terminated (stopped due to Preliminary results were promising when interim analysis performed but terminated due to primary investigators left recruitment site.) | |||
| Unilateral Versus Bilateral Spinal Anesthesia in Day Case Procedures: Difference in Block Characteristics, Micturition Quality and Discharge Time[NCT01877356] | 25 participants (Actual) | Interventional | 2012-12-31 | Terminated (stopped due to intermittent evaluation of results: high incendence of complications) | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
"To determine the change in interstitial cystitis symptom index at baseline, 2 hours, 2 weeks, 6 weeks and 3 months after hydrodistention with preemptive pudendal nerve block (1% Lidocaine) compared to hydrodistention with placebo (saline).~The IC symptom index questionnaire consists of 4 questions on IC symptoms. 2 of the questions have 6 answer choices ranging from 0-never, to 5-almost always. 1 question has 6 answer choices ranging from 0-never to 5-usually. 1 question has 7 answer choices ranging from 0-never to 6-5 or more times. The numerical score for each question are added together, with a minimum score of 0 and a maximum score of 21. A higher score indicates greater severity of IC symptoms." (NCT02517996)
Timeframe: Baseline, 2 weeks, 6 weeks, 3 months (Up to 3 months)
| Intervention | score on a scale (Mean) | |||
|---|---|---|---|---|
| Baseline | 2 weeks | 6 weeks | 12 weeks | |
| 1% Lidocaine | 12.5 | 11.43 | 11.8 | 10 |
| Normal Saline | 10 | 9 | 8.67 | 5 |
"To determine the change in pain at 2 hours, 2 weeks, 6 weeks, and 3 months postoperatively in patients undergoing hydrodistention with preemptive pudendal nerve block (1% Lidocaine) compared to hydrodistention with placebo (saline) using the visual analog scale (VAS).~VAS consists of a 10cm horizontal line with the minimum endpoint labeled no pain (0) and maximum labeled worst pain ever (10). Patients placed a mark on the point that corresponds to the level of pain severity they felt. The cm distance from the low end of the VAS to the patient's mark is used as the numerical index of the intensity of pain. Pain scores of 3.0-5.4 cm are moderate, over 5.4 indicates severe pain." (NCT02517996)
Timeframe: Baseline, 2 hours, 2 weeks, 6 weeks, 3 months (Up to 3 months)
| Intervention | score on a scale (Mean) | ||||
|---|---|---|---|---|---|
| Pre operative VAS score | Post operative VAS score | 2 week post operative VAS scores | 6 week post operative VAS score | 12 weeks post operative VAS score | |
| 1% Lidocaine | 3.125 | 3.75 | 2.7 | 3 | 2.6 |
| Normal Saline | 4.5 | 5 | 4.8 | 4.33 | 2 |
"To determine the change in pelvic urgency, pain and frequency (PUF) questionnaire at baseline, 2 hours, 2 weeks, 6 weeks and 3 months after hydrodistention with preemptive pudendal nerve block (1% Lidocaine) compared to hydrodistention with placebo (saline).~The Pelvic Urgency, Pain, and Frequency Patient Symptom Scale asks 11 questions, 7 on PUF symptoms, 4 on how bothersome PUF symptoms are. Symptom questions include 3, 4, or 5 ranked answers, with higher answers indicating more voids, or greater frequency of pain. The bother questions each of 4 ranked answers from 0-never, to 3-always. The symptom score is added, the bother score is added, and then the total score is added. The total PUF score is then reported. The minimum score is 0 and the maximum score is 35, and a higher score indicates greater symptoms and higher bother from pelvic pain and frequency." (NCT02517996)
Timeframe: Baseline, 2 hours, 2 weeks, 6 weeks, 3 months (Up to 3 months)
| Intervention | score on a scale (Mean) | |||
|---|---|---|---|---|
| Baseline | 2 weeks | 6 weeks | 12 weeks | |
| 1% Lidocaine | 22.63 | 18.83 | 18.2 | 17.2 |
| Normal Saline | 19 | 17.4 | 16.7 | 14 |
"To determine the change in problem index (O'Leary Sant) at baseline, 2 hours, 2 weeks, 6 weeks and 3 months after hydrodistention with preemptive pudendal nerve block (1% Lidocaine) compared to hydrodistention with placebo (saline).~The IC problem index questionnaire consists of 4 questions on how much of a problem a patient's IC symptoms cause them. Each question has 5 answer choices ranging from 0-no problem, to 4-big problem. The numerical score for each question are added together, with a minimum score of 0 and a maximum score of 16. A higher score indicates that IC symptoms cause more problems for the patient." (NCT02517996)
Timeframe: Baseline, 2 hours, 2 weeks, 6 weeks, 3 months (Up to 3 months)
| Intervention | score on a scale (Mean) | |||
|---|---|---|---|---|
| Baseline | 2 weeks | 6 weeks | 12 weeks | |
| 1% Lidocaine | 11.75 | 9.71 | 10 | 9.6 |
| Normal Saline | 9.43 | 8.6 | 7.33 | 6 |
1 review available for lidocaine and Urination Disorders
| Article | Year |
|---|---|
An analysis of the complications of extradural and caudal block.
Topics: Adult; Aged; Anesthesia, Spinal; Back Pain; Blood Pressure; Catheterization; Dura Mater; Epinephrine | 1969 |
7 trials available for lidocaine and Urination Disorders
| Article | Year |
|---|---|
Intrathecal chloroprocaine vs. lidocaine in day-case surgery: recovery, discharge and effect of pre-hydration on micturition.
Topics: Adult; Aged; Ambulatory Surgical Procedures; Anesthesia Recovery Period; Anesthesia, Spinal; Anesthe | 2014 |
Hydrodistension under local anesthesia for patients with suspected painful bladder syndrome/interstitial cystitis: safety, diagnostic potential and therapeutic efficacy.
Topics: Administration, Intravesical; Adult; Aged; Anesthesia, Local; Anesthetics, Local; Cystitis, Intersti | 2009 |
[Effect of painless urethral catheterization combined with lidocaine on urethral irritation].
Topics: Adult; Humans; Lidocaine; Male; Middle Aged; Urinary Catheterization; Urinary Catheters; Urination D | 2012 |
Urinary bladder scanning after day-case arthroscopy under spinal anaesthesia: comparison between lidocaine, ropivacaine, and levobupivacaine.
Topics: Adolescent; Adult; Amides; Anesthesia, Spinal; Anesthetics, Local; Arthroscopy; Bupivacaine; Double- | 2003 |
Urinary bladder scanning after day-case arthroscopy under spinal anaesthesia: comparison between lidocaine, ropivacaine, and levobupivacaine.
Topics: Adolescent; Adult; Amides; Anesthesia, Spinal; Anesthetics, Local; Arthroscopy; Bupivacaine; Double- | 2003 |
Urinary bladder scanning after day-case arthroscopy under spinal anaesthesia: comparison between lidocaine, ropivacaine, and levobupivacaine.
Topics: Adolescent; Adult; Amides; Anesthesia, Spinal; Anesthetics, Local; Arthroscopy; Bupivacaine; Double- | 2003 |
Urinary bladder scanning after day-case arthroscopy under spinal anaesthesia: comparison between lidocaine, ropivacaine, and levobupivacaine.
Topics: Adolescent; Adult; Amides; Anesthesia, Spinal; Anesthetics, Local; Arthroscopy; Bupivacaine; Double- | 2003 |
Pilot study of the feasibility of in-office bladder distention using electromotive drug adminstration (EMDA).
Topics: Adult; Anesthesia, Local; Anesthetics, Local; Cystitis, Interstitial; Cystoscopy; Feasibility Studie | 2005 |
Extradural analgesia in obstetrics: a controlled trial of carbonated lignocaine and bupivacaine hydrochloride with or without adrenaline.
Topics: Anesthesia, Epidural; Anesthesia, Obstetrical; Back Pain; Bupivacaine; Epinephrine; Female; Headache | 1976 |
[Micturition disorders following spinal anesthesia of different durations of action (lidocaine 2% versus bupivacaine 0.5%)].
Topics: Adult; Anesthesia, Spinal; Bupivacaine; Double-Blind Method; Female; Germany; Humans; Lidocaine; Mal | 1992 |
9 other studies available for lidocaine and Urination Disorders
| Article | Year |
|---|---|
Intermittent urethral catheterisation: the reality of the lubricants and catheters in the clinical practice of a Brazilian service.
Topics: Adolescent; Adult; Ambulatory Care Facilities; Anesthetics, Local; Brazil; Catheters; Child; Equipme | 2016 |
Lignocaine test and detrusor instability.
Topics: Aged; Humans; Lidocaine; Male; Middle Aged; Muscle, Smooth; Prostatectomy; Prostatic Hyperplasia; Ur | 1983 |
Acquired methemoglobinemia from multiple oxidants.
Topics: Administration, Topical; Adult; Analgesia, Epidural; Blood Gas Analysis; Bupivacaine; Cytochrome-B(5 | 1993 |
Cauda equina syndrome after spinal anaesthesia with hyperbaric 5% lignocaine: a review of six cases of cauda equina syndrome reported to the Swedish Pharmaceutical Insurance 1993-1997.
Topics: Adult; Adverse Drug Reaction Reporting Systems; Anesthesia, Spinal; Anesthetics, Local; Cauda Equina | 1999 |
Long duration subarachnoid anaesthesia with continuous epidural block.
Topics: Adolescent; Adult; Aged; Anesthesia, Epidural; Anesthesia, Spinal; Cachexia; Dibucaine; Drug Combina | 1979 |
Catheterization after long- and short-acting local anesthetics for continuous caudal block for vaginal delivery.
Topics: Anesthesia, Caudal; Anesthesia, Epidural; Anesthesia, Obstetrical; Anesthetics, Local; Bupivacaine; | 1977 |
Local anesthetic creams.
Topics: Anesthetics, Local; Drug Combinations; Ear Diseases; Female; Herpes Genitalis; Humans; Lidocaine; Li | 1988 |
[Effects of 3-methyl-4-oxo-2-phenyl-N-[2-piperidinyl) ethyl]-4H-1-benzopyran-8-carboxyamide hydrochloride monohydrate (FL-155), a new anti-pollakiuria agent, on rhythmic bladder contractions in anesthetized rats].
Topics: Animals; Atropine; Flavoxate; Lidocaine; Male; Periodicity; Piperidines; Rats; Rats, Inbred Strains; | 1986 |
[Traumatic intervertebral disk disorders. A study of 31 new cases].
Topics: Adult; Back Pain; Female; Humans; Intervertebral Disc; Intervertebral Disc Displacement; Lidocaine; | 1971 |