Page last updated: 2024-10-28

lidocaine and Urinary Incontinence, Stress

lidocaine has been researched along with Urinary Incontinence, Stress in 11 studies

Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.

Urinary Incontinence, Stress: Involuntary discharge of URINE as a result of physical activities that increase abdominal pressure on the URINARY BLADDER without detrusor contraction or overdistended bladder. The subtypes are classified by the degree of leakage, descent and opening of the bladder neck and URETHRA without bladder contraction, and sphincter deficiency.

Research Excerpts

ExcerptRelevanceReference
"Alkalinized lidocaine and heparin have been reported to provide relief from pain and urgency symptoms associated with IC."5.20Heparin and alkalinized lidocaine versus alkalinized lidocaine for treatment of interstitial cystitis symptoms. ( Argade, S; Koziol, JA; Parsons, CL; Proctor, JG; Zupkas, P, 2015)
" No significant difference was observed in the proportion of women requesting analgesia and in the total dosage of analgesics between the two groups."2.79Effect of local infiltration analgesia on post-operative pain following TVT-O: a double-blind, placebo-controlled randomized study. ( Di Carlo, C; Fabozzi, A; Formisano, C; Nappi, C; Tommaselli, GA, 2014)
"The primary long-term outcome was backache occurring within 3 months of the birth persisting for longer than 6 weeks."2.76Long-term effects of epidural analgesia in labor: a randomized controlled trial comparing high dose with two mobile techniques. ( Lancashire, RJ; MacArthur, C; Moore, PA; Shennan, A; Wilson, MJ, 2011)
" Two women received a toxic dose of lidocaine, and both were in the VH + VR group."1.56Lidocaine Use in Vaginal Surgery and Risk of Toxicity. ( Brueseke, TJ; Connolly, A; Geller, EJ; Husk, KE; Willis-Gray, MG, 2020)
"Lidocaine cytotoxicity has been reported in some cell types, which could affect its use as a local anesthetic in cell-based therapy."1.35In vitro and in vivo effect of lidocaine on rat muscle-derived cells for treatment of stress urinary incontinence. ( Chancellor, MB; de Miguel, F; Furuta, A; Honda, M; Jankowski, RJ; Kim, DK; Pruchnic, R; Yoshimura, N, 2009)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19901 (9.09)18.7374
1990's3 (27.27)18.2507
2000's3 (27.27)29.6817
2010's3 (27.27)24.3611
2020's1 (9.09)2.80

Authors

AuthorsStudies
Willis-Gray, MG1
Husk, KE1
Brueseke, TJ1
Connolly, A1
Geller, EJ1
Tommaselli, GA1
Di Carlo, C1
Formisano, C1
Fabozzi, A1
Nappi, C1
Parsons, CL1
Koziol, JA1
Proctor, JG1
Zupkas, P1
Argade, S1
Park, AJ1
Fisch, JM1
Fisch, JL1
Walters, MD1
Kim, DK1
Jankowski, RJ1
Pruchnic, R1
de Miguel, F1
Yoshimura, N1
Honda, M1
Furuta, A1
Chancellor, MB2
Wilson, MJ1
Moore, PA1
Shennan, A1
Lancashire, RJ1
MacArthur, C1
Shafik, A1
Thind, P2
Lose, G2
Bagi, P1
Mieszczak, C1
Jung, SY1
Fraser, MO1
Ozawa, H1
Yokoyama, O1
Yoshiyama, M1
De Groat, WC1
Growdon, WA1
Lebherz, TB1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Evaluation of Postoperative Pain After Tension-free Obturator Tape Operation (TVT-O) With or Without Local Anesthetic[NCT03479996]22 participants (Actual)Interventional2018-11-13Completed
AMPLIFY: Amplifying Sensation in Underactive Bladder[NCT04516434]20 participants (Anticipated)Interventional2021-09-01Recruiting
Potential Biomarkers in the Study of Overactive Bladder in Women[NCT03516292]108 participants (Anticipated)Observational2018-01-29Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

3 trials available for lidocaine and Urinary Incontinence, Stress

ArticleYear
Effect of local infiltration analgesia on post-operative pain following TVT-O: a double-blind, placebo-controlled randomized study.
    Archives of gynecology and obstetrics, 2014, Volume: 290, Issue:2

    Topics: Analgesia; Analgesics; Anesthesia, Local; Anesthetics, Local; Double-Blind Method; Drug Administrati

2014
Heparin and alkalinized lidocaine versus alkalinized lidocaine for treatment of interstitial cystitis symptoms.
    The Canadian journal of urology, 2015, Volume: 22, Issue:2

    Topics: Adult; Aged; Anesthetics, Local; Anticoagulants; Cystitis, Interstitial; Drug Therapy, Combination;

2015
Long-term effects of epidural analgesia in labor: a randomized controlled trial comparing high dose with two mobile techniques.
    Birth (Berkeley, Calif.), 2011, Volume: 38, Issue:2

    Topics: Adult; Analgesia, Obstetrical; Anesthesia, Epidural; Anesthetics, Local; Back Pain; Bupivacaine; Fec

2011

Other Studies

8 other studies available for lidocaine and Urinary Incontinence, Stress

ArticleYear
Lidocaine Use in Vaginal Surgery and Risk of Toxicity.
    Female pelvic medicine & reconstructive surgery, 2020, Volume: 26, Issue:9

    Topics: Aged; Anesthetics, Local; Dose-Response Relationship, Drug; Female; Humans; Hysterectomy; Length of

2020
Transient obturator neuropathy due to local anesthesia during transobturator sling placement.
    International urogynecology journal and pelvic floor dysfunction, 2009, Volume: 20, Issue:2

    Topics: Adult; Anesthetics, Local; Bupivacaine; Female; Humans; Lidocaine; Nervous System Diseases; Obturato

2009
In vitro and in vivo effect of lidocaine on rat muscle-derived cells for treatment of stress urinary incontinence.
    Urology, 2009, Volume: 73, Issue:2

    Topics: Anesthetics, Local; Animals; Cells, Cultured; Female; Lidocaine; Muscle Cells; Rats; Rats, Sprague-D

2009
Stress urinary incontinence: new concept of pathogenesis and treatment by pudendal canal decompression.
    Advances in experimental medicine and biology, 2003, Volume: 539, Issue:Pt A

    Topics: Adult; Anesthesia, Local; Cough; Decompression, Surgical; Electromyography; Female; Follow-Up Studie

2003
The effect of bilateral pudendal blockade on the adjunctive urethral closure forces in healthy females.
    Scandinavian journal of urology and nephrology, 1994, Volume: 28, Issue:3

    Topics: Adult; Cough; Female; Humans; Lidocaine; Muscle Contraction; Muscle, Skeletal; Nerve Block; Pelvic F

1994
Influence of pudendal nerve blockade on stress relaxation in the female urethra.
    Neurourology and urodynamics, 1996, Volume: 15, Issue:1

    Topics: Adult; Anesthetics, Local; Autonomic Nervous System; Drug Combinations; Elasticity; Female; Humans;

1996
Urethral afferent nerve activity affects the micturition reflex; implication for the relationship between stress incontinence and detrusor instability.
    The Journal of urology, 1999, Volume: 162, Issue:1

    Topics: Anesthetics, Local; Animals; Capsaicin; Enzyme Inhibitors; Female; Lidocaine; Muscle Contraction; Mu

1999
Urethral afferent nerve activity affects the micturition reflex; implication for the relationship between stress incontinence and detrusor instability.
    The Journal of urology, 1999, Volume: 162, Issue:1

    Topics: Anesthetics, Local; Animals; Capsaicin; Enzyme Inhibitors; Female; Lidocaine; Muscle Contraction; Mu

1999
Urethral afferent nerve activity affects the micturition reflex; implication for the relationship between stress incontinence and detrusor instability.
    The Journal of urology, 1999, Volume: 162, Issue:1

    Topics: Anesthetics, Local; Animals; Capsaicin; Enzyme Inhibitors; Female; Lidocaine; Muscle Contraction; Mu

1999
Urethral afferent nerve activity affects the micturition reflex; implication for the relationship between stress incontinence and detrusor instability.
    The Journal of urology, 1999, Volume: 162, Issue:1

    Topics: Anesthetics, Local; Animals; Capsaicin; Enzyme Inhibitors; Female; Lidocaine; Muscle Contraction; Mu

1999
Modified Pereyra procedure under local anesthesia.
    Obstetrics and gynecology, 1986, Volume: 68, Issue:2

    Topics: Aged; Anesthesia, Local; Female; Humans; Length of Stay; Lidocaine; Methods; Middle Aged; Time Facto

1986