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lidocaine and Tuberculosis, Multidrug-Resistant

lidocaine has been researched along with Tuberculosis, Multidrug-Resistant in 2 studies

Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.

Tuberculosis, Multidrug-Resistant: Tuberculosis resistant to chemotherapy with two or more ANTITUBERCULAR AGENTS, including at least ISONIAZID and RIFAMPICIN. The problem of resistance is particularly troublesome in tuberculous OPPORTUNISTIC INFECTIONS associated with HIV INFECTIONS. It requires the use of second line drugs which are more toxic than the first line regimens. TB with isolates that have developed further resistance to at least three of the six classes of second line drugs is defined as EXTENSIVELY DRUG-RESISTANT TUBERCULOSIS.

Research Excerpts

ExcerptRelevanceReference
" Pharmacokinetic measures were calculated using noncompartmental analysis."2.87Effect of Coadministration of Lidocaine on the Pain and Pharmacokinetics of Intramuscular Amikacin in Children With Multidrug-Resistant Tuberculosis: A Randomized Crossover Trial. ( Draper, HR; Garcia-Prats, AJ; Hesseling, AC; McIlleron, HM; Norman, J; Rose, PC; Schaaf, HS; Seddon, JA, 2018)
"Lidocaine has been shown to be an effective anaesthetic diluent for some intramuscular injections, but has not been investigated with KM in the treatment of adult patients with MDR-TB."2.87Effect of lidocaine on kanamycin injection-site pain in patients with multidrug-resistant tuberculosis. ( Chirehwa, MT; Court, RG; de Vries, N; Gumbo, T; Harding, J; Maartens, G; McIlleron, H; Stewart, A; Wiesner, L, 2018)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Garcia-Prats, AJ1
Rose, PC1
Draper, HR1
Seddon, JA1
Norman, J1
McIlleron, HM1
Hesseling, AC1
Schaaf, HS1
Court, RG1
Wiesner, L1
Chirehwa, MT1
Stewart, A1
de Vries, N1
Harding, J1
Gumbo, T1
McIlleron, H1
Maartens, G1

Trials

2 trials available for lidocaine and Tuberculosis, Multidrug-Resistant

ArticleYear
Effect of Coadministration of Lidocaine on the Pain and Pharmacokinetics of Intramuscular Amikacin in Children With Multidrug-Resistant Tuberculosis: A Randomized Crossover Trial.
    The Pediatric infectious disease journal, 2018, Volume: 37, Issue:12

    Topics: Adolescent; Amikacin; Anesthetics, Local; Antitubercular Agents; Area Under Curve; Child; Cross-Over

2018
Effect of lidocaine on kanamycin injection-site pain in patients with multidrug-resistant tuberculosis.
    The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease, 2018, 08-01, Volume: 22, Issue:8

    Topics: Adult; Anesthetics, Local; Anti-Bacterial Agents; Cross-Over Studies; Female; HIV Infections; Humans

2018