Page last updated: 2024-10-28

lidocaine and Tenosynovitis

lidocaine has been researched along with Tenosynovitis in 19 studies

Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.

Tenosynovitis: Inflammation of the synovial lining of a tendon sheath. Causes include trauma, tendon stress, bacterial disease (gonorrhea, tuberculosis), rheumatic disease, and gout. Common sites are the hand, wrist, shoulder capsule, hip capsule, hamstring muscles, and Achilles tendon. The tendon sheaths become inflamed and painful, and accumulate fluid. Joint mobility is usually reduced.

Research Excerpts

ExcerptRelevanceReference
" Inclusion criteria were documented radial synergy test, Eichoff's test, and ≥90% pain relief after lidocaine/corticosteroid injection."4.31The Radial Synergy Test: An Aid to Diagnose de Quervain's Tenosynovitis. ( Hogan, CJ; Langford, MA; Langford, PN; Lee, C; Ruland, RT; Sullivan, GE, 2023)
"A 26 year old female, was given an intra-lesional injection of 24 mg methyl prednisolone acetate (MPA) with 15 mg lidocaine for treatment of DeQuervain's tenosynovitis."3.79An unexpected temporary suppression of lactation after a local corticosteroid injection for tenosynovitis. ( Babwah, TJ; Maharaj, RG; Nunes, P, 2013)

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19906 (31.58)18.7374
1990's6 (31.58)18.2507
2000's2 (10.53)29.6817
2010's4 (21.05)24.3611
2020's1 (5.26)2.80

Authors

AuthorsStudies
Lee, C1
Langford, PN1
Sullivan, GE1
Langford, MA1
Hogan, CJ1
Ruland, RT1
Knackstedt, R1
Tyler, J1
Bernard, S1
Babwah, TJ1
Nunes, P1
Maharaj, RG1
Sibbitt, WL1
Michael, AA1
Poole, JL1
Chavez-Chiang, NR1
Delea, SL1
Bankhurst, AD1
Hashiuchi, T1
Sakurai, G1
Morimoto, M1
Komei, T1
Takakura, Y1
Tanaka, Y1
Kamel, M1
Moghazy, K1
Eid, H1
Mansour, R1
KOEROESSY, F1
SZAKACS, F1
Denkler, K1
Weiser, HI1
Gould, N1
Murphy, D1
Failla, JM2
Koniuch, MP1
Tan, MY1
Low, CK1
Tan, SK1
Weiss, AP1
Akelman, E1
Tabatabai, M1
Zingas, C1
Van Holsbeeck, M1
Rankin, ME1
Rankin, EA1
An, HK1
Paul, AS1
Davies, DR1
Haines, JF1
McKenzie, JM1
Dupont, C1
Ciaburro, H1
Prévost, Y1
Cloutier, G1

Clinical Trials (5)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Randomized Controlled Trial of the Reciprocating Procedure Device Versus the Conventional Syringe in Syringe-and-Needle Procedures[NCT00651625]437 participants (Actual)Interventional2004-11-30Completed
[NCT02591953]22 participants (Actual)Interventional2015-11-30Terminated (stopped due to Unable to meet enrollment and follow up criteria)
Long Term Effectiveness of Trigger Finger Injections With Triamcinolone vs. Dexamethasone[NCT03641508]Phase 469 participants (Actual)Interventional2014-01-31Completed
Needle-Free Injection of Lidocaine for Local Anesthesia Prior to Trigger Digit Injection[NCT02084706]60 participants (Actual)Interventional2014-03-31Completed
Pain With Trigger Finger Injection: A Comparison of Steroid Alone Versus Steroid/Lidocaine Mixture[NCT02421419]Phase 426 participants (Actual)Interventional2015-06-30Terminated (stopped due to Study closed; recruitment problems)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Adverse Outcomes (Hemorrhage, Infection, Hematoma, Extravasation)

(NCT00651625)
Timeframe: during procedure, 2 weeks afterwards, and 6 months afterwards

Interventionparticipants (Number)
1Conventional Syringe0
2RPD Syringe0

Aspirated Fluid Volume

Aspirated fluid volume during procedure (NCT00651625)
Timeframe: during procedure

Interventionml (Mean)
1Conventional Syringe7.2
2RPD Syringe14.5

Pain Using VAS (Visual Analogue Pain Scale)

0-10 cm VAS pain scale at 2 weeks compared to 0-10 cm VAS pain scale at 0 weeks where 0= no pain, and 10 = the worst pain imaginable. The difference (2 week VAS-0 week VAS) is the primary outcome measure. (NCT00651625)
Timeframe: 2 weeks

Interventioncm (Mean)
1Conventional Syringe5.2
2RPD Syringe6.2

Physician Satisfaction

"0- 10 cm visual analogue satisfaction scale (VASS)~0-10 cm VASS at 2 weeks compared to 0-10 cm VASS pain scale at 0 weeks where 0= completely dissatisfied, and 10 = completely satsified. The difference (2 week VAS-0 week VAS) is the outcome measure" (NCT00651625)
Timeframe: during procedure

Interventioncm (Mean)
1Conventional Syringe6.4
2RPD Syringe8.5

Number of Participants With no Symptoms of Trigger Finger

"Number of participants with no symptoms of trigger finger 1 year after the initial encounter for both groups. Outcomes were determined clinically:~The Quinnell grading system was used for objectively evaluating the trigger finger. This grading system is a scale of 0-4 for severity of triggering with 0 being no triggering." (NCT03641508)
Timeframe: 1 year

InterventionParticipants (Count of Participants)
Triamcinolone20
Dexamethasone13

Number of Participants With no Symptoms of Trigger Finger

"Number of participants with no symptoms of trigger finger 6 months after the initial encounter for both groups. Outcomes were determined clinically:~The Quinnell grading system was used for objectively evaluating the trigger finger. This grading system is a scale of 0-4 for severity of triggering with 0 being no triggering." (NCT03641508)
Timeframe: 6 months

InterventionParticipants (Count of Participants)
Triamcinolone23
Dexamethasone12

Number of Participants With no Symptoms of Trigger Finger

"Number of participants with no symptoms of trigger finger 6 weeks after the initial encounter for both groups. Outcomes were determined clinically:~The Quinnell grading system was used for objectively evaluating the trigger finger. This grading system is a scale of 0-4 for severity of triggering with 0 being no triggering." (NCT03641508)
Timeframe: 6 weeks

InterventionParticipants (Count of Participants)
Triamcinolone28
Dexamethasone9

Difference in Visual-analog Score (VAS) for Anticipated Pain Prior to Injection and Actual Pain After Injection

Members of both study groups completed the Visual Analog Scale (VAS) pain assessment both prior for anticipated pain and after injection for actual pain; these recorded scores were the primary study endpoint and were later compared to determine the difference in anticipated pain versus actual pain experienced. The VAS ranges from 0-10, where 0 is no pain and 10 is worst possible pain. The outcome measure is the mean anticipated pain minus the actual pain experienced. (NCT02084706)
Timeframe: Our outcome measure was collected within the 60 seconds before and following the steroid injection.

Interventionunits on a scale (Mean)
Triamcinolone (20 g) and 2% Lidocaine Injection Over A1 Pulley1.6
J-tip Lidocaine Administration, Then Steroid Injection2.8

Degree of Triggering

A Green classification number (0-4) is given to each subject pre-injection and at 6 weeks post-injection based on their degree of triggering. 0 = No triggering, no pain; 1 = Pre-triggering; pain, history of catching, but not demonstrable on physical examination; tenderness over the A1 pulley; 2 = Active; demonstrable catching, but the patient can actively extend the digit; 3= Passive; demonstrable catching requiring passive extension or inability to actively flex; and 4 = Contracture; demonstrable catching with a fixed flexion contracture of the PIP joint. (NCT02421419)
Timeframe: Patients are assessed pre-injection objectively by investigator and at 6 weeks post-injection subjectively via Patient Survey

,,
InterventionParticipants (Count of Participants)
Green classification 0 (pre-injection)Green classification 1 (pre-injection)Green classification 2 (pre-injection)Green classification 3 (pre-injection)Green Classification 4 (pre-injection)Green classification 0 (6-weeks post-injection)Green classification 1 (6-weeks post-injection)Green classification 2 (6-weeks post-injection)Green classification 3 (6-weeks post-injection)Green classification 4 (6-weeks post-injection)
Corticosteroid Alone (CS) Group0240020220
Corticosteroid/Lidocaine (CSL) Group01100010271
Corticosteroid/Saline (CSS) Group0160110421

Number of Participants With Adverse Effects

Incidence of adverse effects (NCT02421419)
Timeframe: Patients are assessed 1 minute post-injection, 10 minutes post-injection, and at 6 week post-injection.

,,
InterventionParticipants (Count of Participants)
Adverse effects 1 minute post-injectionAdverse effects 10 minutes post-injectionAdverse effects 6 weeks post-injection
Corticosteroid Alone (CS) Group000
Corticosteroid/Lidocaine (CSL) Group000
Corticosteroid/Saline (CSS) Group000

Presence of Triggering

Patients are asked how often their finger triggers - not at all, rarely, occasionally, or frequently at time intervals indicated in the outcome measure time frame. Count of participants for each of these answers was collected. (NCT02421419)
Timeframe: Patients are assessed pre-injection (baseline), 1 minute post-injection, 10 minutes post-injection, and 6 weeks post-injection

,,
InterventionParticipants (Count of Participants)
Triggering frequently pre-injectionTriggering not at all pre-injectionTriggering occasionally pre-injectionTriggering rarely pre-injectionTriggering not at all 1 minute post-injectionTriggering rarely 1 minute post-injectionTriggering occasionally 1 minute post-injectionTriggering frequently 1 minute post-injectionTriggering same as before 1 minute post-injectionTriggering not at all 10 minutes post-injectionTriggering rarely 10 minutes post-injectionTriggering occasionally 10 minutes post-injectionTriggering frequently 10 minutes post-injectionTriggering same as before 10 min. post-injectionTriggering not at all 6 wks post-injectionTriggering rarely 6 wks post-injectionTriggering occasionally 6 weeks post-injectionTriggering frequently 6 wks post-injectiontriggering same as before 6 wks post-injection
Corticosteroid Alone (CS) Group2040301024010130012
Corticosteroid/Lidocaine (CSL) Group7040101082011611018
Corticosteroid/Saline (CSS) Group5210300054000410025

VAS

Visual Analogue Pain Scale (VAS) - measurement of pain on scale of 0 (least) to 10 (worst). (NCT02421419)
Timeframe: Patients are assessed pre-injection (baseline), 1 minute post-injection, 10 minutes post-injection, at 6 weeks post-injection and also asked to recollect their pain at time of injection when seen at 6 weeks post-injection

,,
Interventionunits on a scale (Mean)
VAS pre-injectionVAS 1 minute post-injectionVAS 10 minutes post-injectionVAS 6 weeks post-injectionVAS Recollection
Corticosteroid Alone (CS) Group2.22.32.11.55.2
Corticosteroid/Lidocaine (CSL) Group3.02.21.23.36.6
Corticosteroid/Saline (CSS) Group3.94.93.34.05.9

Reviews

1 review available for lidocaine and Tenosynovitis

ArticleYear
Closed Continuous Irrigation With Lidocaine and Immediate Mobilization for Treatment of Pyogenic Tenosynovitis.
    Techniques in hand & upper extremity surgery, 2017, Volume: 21, Issue:3

    Topics: Anti-Bacterial Agents; Debridement; Female; Follow-Up Studies; Humans; Lidocaine; Male; Range of Mot

2017

Trials

3 trials available for lidocaine and Tenosynovitis

ArticleYear
Nerve blocks at the wrist for painful injections of the palm.
    Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases, 2011, Volume: 17, Issue:4

    Topics: Adrenal Cortex Hormones; Adult; Anesthetics, Local; Dupuytren Contracture; Female; Hand; Humans; Inj

2011
Accuracy of the biceps tendon sheath injection: ultrasound-guided or unguided injection? A randomized controlled trial.
    Journal of shoulder and elbow surgery, 2011, Volume: 20, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Local; Female; Humans; Injections, Intra-Articular; Lid

2011
Steroid versus placebo injection for trigger finger.
    The Journal of hand surgery, 1995, Volume: 20, Issue:4

    Topics: Administration, Topical; Anti-Inflammatory Agents; Betamethasone; Double-Blind Method; Female; Finge

1995
Steroid versus placebo injection for trigger finger.
    The Journal of hand surgery, 1995, Volume: 20, Issue:4

    Topics: Administration, Topical; Anti-Inflammatory Agents; Betamethasone; Double-Blind Method; Female; Finge

1995
Steroid versus placebo injection for trigger finger.
    The Journal of hand surgery, 1995, Volume: 20, Issue:4

    Topics: Administration, Topical; Anti-Inflammatory Agents; Betamethasone; Double-Blind Method; Female; Finge

1995
Steroid versus placebo injection for trigger finger.
    The Journal of hand surgery, 1995, Volume: 20, Issue:4

    Topics: Administration, Topical; Anti-Inflammatory Agents; Betamethasone; Double-Blind Method; Female; Finge

1995
Steroid versus placebo injection for trigger finger.
    The Journal of hand surgery, 1995, Volume: 20, Issue:4

    Topics: Administration, Topical; Anti-Inflammatory Agents; Betamethasone; Double-Blind Method; Female; Finge

1995
Steroid versus placebo injection for trigger finger.
    The Journal of hand surgery, 1995, Volume: 20, Issue:4

    Topics: Administration, Topical; Anti-Inflammatory Agents; Betamethasone; Double-Blind Method; Female; Finge

1995
Steroid versus placebo injection for trigger finger.
    The Journal of hand surgery, 1995, Volume: 20, Issue:4

    Topics: Administration, Topical; Anti-Inflammatory Agents; Betamethasone; Double-Blind Method; Female; Finge

1995
Steroid versus placebo injection for trigger finger.
    The Journal of hand surgery, 1995, Volume: 20, Issue:4

    Topics: Administration, Topical; Anti-Inflammatory Agents; Betamethasone; Double-Blind Method; Female; Finge

1995
Steroid versus placebo injection for trigger finger.
    The Journal of hand surgery, 1995, Volume: 20, Issue:4

    Topics: Administration, Topical; Anti-Inflammatory Agents; Betamethasone; Double-Blind Method; Female; Finge

1995

Other Studies

15 other studies available for lidocaine and Tenosynovitis

ArticleYear
The Radial Synergy Test: An Aid to Diagnose de Quervain's Tenosynovitis.
    Hand (New York, N.Y.), 2023, Volume: 18, Issue:2_suppl

    Topics: De Quervain Disease; Humans; Lidocaine; Pain; Prospective Studies; Retrospective Studies; Tenosynovi

2023
An unexpected temporary suppression of lactation after a local corticosteroid injection for tenosynovitis.
    The European journal of general practice, 2013, Volume: 19, Issue:4

    Topics: Adult; Breast Feeding; Female; Glucocorticoids; Humans; Injections, Intralesional; Lactation; Lidoca

2013
Ultrasonographic diagnosis of de Quervain's tenosynovitis.
    Annals of the rheumatic diseases, 2002, Volume: 61, Issue:11

    Topics: Drug Combinations; Humans; Injections, Intralesional; Lidocaine; Prospective Studies; Tendons; Tenos

2002
[TREATMENT OF TENDOVAGINITIS BASED ON 500 CASES].
    Orvosi hetilap, 1964, May-10, Volume: 105

    Topics: Agricultural Workers' Diseases; Calcium Sulfate; Casts, Surgical; Humans; Hungary; Hydrocortisone; L

1964
Helpful hints for injections of wrist and hand region.
    American family physician, 2003, Nov-15, Volume: 68, Issue:10

    Topics: Anesthetics, Local; Carpal Tunnel Syndrome; Finger Joint; Humans; Injections, Intra-Articular; Lidoc

2003
[A splint for stenosing tenovaginitis of the finger].
    Harefuah, 1981, Jan-01, Volume: 100, Issue:1

    Topics: Fingers; Humans; Lidocaine; Splints; Tenosynovitis; Triamcinolone Acetonide

1981
Stenosing tenosynovitis of the flexor hallucis longus tendon at the great toe.
    Foot & ankle, 1981, Volume: 2, Issue:1

    Topics: Adolescent; Adult; Aged; Constriction, Pathologic; Female; Hallux; Humans; Lidocaine; Male; Middle A

1981
De Quervain's tenosynovitis and ganglion over first dorsal extensor retinacular compartment.
    Annals of the Academy of Medicine, Singapore, 1994, Volume: 23, Issue:6

    Topics: Female; Humans; Hydrocortisone; Lidocaine; Male; Middle Aged; Singapore; Synovial Cyst; Tenosynoviti

1994
Treatment of de Quervain's disease.
    The Journal of hand surgery, 1994, Volume: 19, Issue:4

    Topics: Adolescent; Adult; Aged; Betamethasone; Female; Humans; Injections; Lidocaine; Male; Middle Aged; Sp

1994
Injection accuracy and clinical relief of de Quervain's tendinitis.
    The Journal of hand surgery, 1998, Volume: 23, Issue:1

    Topics: Adult; Anesthetics, Local; Betamethasone; Contrast Media; Female; Glucocorticoids; Humans; Iohexol;

1998
Injection therapy for management of stenosing tenosynovitis (de Quervain's disease) of the wrist.
    Journal of the National Medical Association, 1998, Volume: 90, Issue:8

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anesthetics, Local; Anti-Inflammatory Agents; Female; Fo

1998
Trigger finger, a report on a series of cases.
    The Medical journal of Malaysia, 1978, Volume: 33, Issue:1

    Topics: Adult; Aged; Arthritis, Rheumatoid; Female; Fingers; Humans; Injections; Lidocaine; Male; Prednisolo

1978
Surgical treatment of adult trigger finger under local anaesthetic: the method of choice?
    Journal of the Royal College of Surgeons of Edinburgh, 1992, Volume: 37, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Anesthesia, Local; Female; Fingers; Humans; Lidocaine; Male; Middle

1992
Conservative treatment of de Quervain's disease.
    British medical journal, 1972, Dec-16, Volume: 4, Issue:5841

    Topics: Adult; Aged; Female; Humans; Hydrocortisone; Injections; Lidocaine; Male; Methods; Middle Aged; Teno

1972
Hand surgery under wrist block and local infiltration anesthesia, using an upper arm tourniquet.
    Plastic and reconstructive surgery, 1972, Volume: 50, Issue:5

    Topics: Anesthesia, Local; Dupuytren Contracture; Epinephrine; Hand; Humans; Lidocaine; Nerve Compression Sy

1972