Page last updated: 2024-10-28

lidocaine and Temporomandibular Disorders

lidocaine has been researched along with Temporomandibular Disorders in 28 studies

Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.

Research Excerpts

ExcerptRelevanceReference
"Cold detection threshold, warm detection threshold, cold pain threshold, heat pain threshold, mechanical detection threshold, mechanical pain threshold, wind-up ratio and pressure pain threshold were assessed on the skin overlying the masseter at three consecutive days (baseline and immediately after lidocaine 4%/placebo cream)."5.34Topical anaesthesia degree is reduced in temporomandibular disorders patients: A novel approach to assess underlying mechanisms of the somatosensory alterations. ( Baad-Hansen, L; Bonjardim, LR; Conti, PCR; Costa, YM; Ferreira, DMAO; Svensson, P, 2020)
"Morphine 1."2.87Effects of intramuscular morphine in men and women with temporomandibular disorder with myofascial pain. ( Auh, QS; Kang, SK; Lee, YH; Park, H; Ro, JY, 2018)
"Atypical odontalgia is a distressing and unusual chronic orofacial pain condition."2.69Analysis of 50 patients with atypical odontalgia. A preliminary report on pharmacological procedures for diagnosis and treatment. ( Chisholm, K; Cousins, MJ; Vickers, ER; Walker, S, 1998)
"The patient experienced profound numbness of the auricle on the ipsilateral side of the injection that lasted for about an hour following unintended injection to the auriculotemporal nerve."1.35Numbness of the ear following inferior alveolar nerve block: the forgotten complication. ( Chai, WL; Ngeow, WC, 2009)
"Inflammation found in temporomandibular disorders and rheumatoid arthritis may result from mediators released by pain-sensing neurons."1.31Local anesthesia does not block mustard-oil-induced temporomandibular inflammation. ( Haas, DA; Hu, JW; Wong, JK, 2001)

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-19903 (10.71)18.7374
1990's10 (35.71)18.2507
2000's9 (32.14)29.6817
2010's5 (17.86)24.3611
2020's1 (3.57)2.80

Authors

AuthorsStudies
Costa, YM1
Ferreira, DMAO1
Conti, PCR1
Baad-Hansen, L1
Svensson, P1
Bonjardim, LR1
Kang, SK1
Lee, YH1
Park, H1
Ro, JY1
Auh, QS1
Zhou, H1
Hu, K1
Ding, Y1
Hebard, RL1
Kumar, N1
Sardana, R1
Kaur, R1
Jain, A1
Young, AL1
Khan, J1
Thomas, DC1
Quek, SY1
Ngeow, WC1
Chai, WL1
Samiee, A1
Sabzerou, D1
Edalatpajouh, F1
Clark, GT2
Ram, S1
Oliveira, MC1
Parada, CA1
Veiga, MC1
Rodrigues, LR1
Barros, SP1
Tambeli, CH1
Gutta, R1
Louis, PJ1
Modla, Z1
Szabó, I1
Yu, XM1
Sessle, BJ1
Vernon, H1
Hu, JW2
Edwards, RM1
Schiffman, EL1
Braun, BL2
Lindgren, BR1
Vickers, ER1
Cousins, MJ1
Walker, S1
Chisholm, K1
Hirota, W1
Gu, ZY1
Wu, HL1
Wu, QL1
Cao, ZQ1
Zhang, YX1
Brown, FF1
Robinson, ME1
Riley, JL1
Gremillion, HA1
McSolay, J1
Meyers, G1
Wong, JK1
Haas, DA1
Tsukiyama, Y1
Baba, K1
Prasad, KC1
Kamath, MP1
Reddy, KJ1
Raju, K1
Agarwal, S1
Yoda, T1
Imai, H1
Shinjyo, Y1
Sakamoto, I1
Abe, M1
Enomoto, S1
Danzig, W1
May, S1
McNeill, C1
Miller, A1
Wenneberg, B1
Kopp, S1
Gröndahl, HG1
Lark, MR1
Gangarosa, LP1
Kimura, S1
Hatano, Y1
Yokozuka, S1
Chem, ZS1
Chao, SY1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Transcranial Direct Current Stimulation for the Treatment of Parkinson's Disease[NCT00082342]Phase 225 participants (Actual)Interventional2003-03-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Bradykinesia Measure Before and After Real and Sham tDCS.

Bradykinesia refers to the slowness in executing a movement. Bradykinesia was assessed by measuring the time in seconds it takes to do the following sequence, 10 times: 1) hand closing and opening while squeezing a ball 2) elbow flexion 3) hand closing and opening, and 4) elbow extension. Subjects were allowed to practice these hand and arm movements until performance appeared not to get faster, and then were abstained from further practice to minimize learning effects. The time it takes subjects to execute the entire sequence 10 times with either the left or right arm/hand was measured. Means are reported for each group. (NCT00082342)
Timeframe: baseline, 1 day post, 1 month post, 3 months post tDCS

,,,
Interventionseconds (Mean)
Baseline1 day post tDCS1 month post tDCS3 months post tDCS
Real tDCS While Off Medication14.58.99.49.7
Real tDCS While on Medication12.38.59.19.0
Sham tDCS While Off Medication14.411.111.711.6
Sham tDCS While on Medication12.310.510.510.4

Gait Speed Before and After Real and Sham tDCS.

Gait speed was measured by the time it took the subject to walk 10m. Subjects were instructed to walk at a fast pace without taking the risk of falling, wearing the same shoes and using assistive devices consistently if needed. Gait speed was measured at baseline and post-tDCS. (NCT00082342)
Timeframe: baseline, 1 day post, 1 month post, 3 months post-tDCS

,,,
InterventionSeconds (Mean)
BaselineOne day post tDCSOne month post tDCSThree month post tDCS
Real tDCS While Off Medication9.77.57.69.0
Real tDCS While on Medication8.77.27.07.2
Sham tDCS While Off Medication9.59.810.99.7
Sham tDCS While on Medication8.67.68.78.8

UPDRS Motor Scores Before and After Real tDCS Course and After Sham tDCS Course.

The Motor Unified Parkinson's Disease Rating Scale (UPDRS) includes only the motor assessment of the UPDRS (Part III) and examines speech, facial expression, tremor at rest, action tremor, rigidity, finger taps, hand movements, hand pronation and supination, leg agility, arising from chair, posture, gait, postural stability and body bradykinesia. The scores range from 0 (no motor impairment) to 108 (severe motor impairment). The Motor UPDRS was administred at baseline and at 1 day post, 1 month post, and 3 months post tDCS or sham. Subjects were assessed on medication and off medication. (NCT00082342)
Timeframe: baseline, 1 day post, 1 month post, and 3 months post real and sham tDCS

,,,
Interventionunits on a scale (Mean)
Baseline1 day post tDCS1 month post tDCS3 months post tDCS
Real tDCS While Off Medication34.031.531.434.0
Real tDCS While on Medication22.220.422.723.1
Sham tDCS While Off Medication26.529.029.027.1
Sham tDCS While on Medication17.515.618.617.6

UPDRS Total Scores Before and After Real tDCS Course and After Sham tDCS Course.

The Total Unified Parkinson's Disease Rating Scale (UPDRS) is an overall clinical rating scale that quantifies the signs and symptoms of Parkinson's disease. The total UPDRS score was obtained from subject examination, subject interviews and questionnaires. The UPDRS encompasses measurement of mentation, behavior, mood, activities of daily living and motor skills. The total UPDRS scores ranges from 0 (not affected) to 176 (most severely affected). The UPDRS was administred at baseline and at 1 day post, 1 month post, and 3 months post tDCS or sham, while on medication and off medication. (NCT00082342)
Timeframe: baseline, 1 day post, 1 month post, 3 months post-tDCS

,,,
Interventionunits on a scale (Mean)
Baseline1 day post tDCS1 month post tDCS3 months post tDCS
Real tDCS While Off Medication58.454.156.160.1
Real tDCS While on Medication42.536.942.543.4
Sham tDCS While Off Medication53.650.454.452.4
Sham tDCS While on Medication39.532.036.135.5

Reviews

1 review available for lidocaine and Temporomandibular Disorders

ArticleYear
An evidence-based assessment of occlusal adjustment as a treatment for temporomandibular disorders.
    The Journal of prosthetic dentistry, 2001, Volume: 86, Issue:1

    Topics: Adult; Anesthetics, Local; Anti-Inflammatory Agents; Betamethasone; Biofeedback, Psychology; Bruxism

2001

Trials

7 trials available for lidocaine and Temporomandibular Disorders

ArticleYear
Topical anaesthesia degree is reduced in temporomandibular disorders patients: A novel approach to assess underlying mechanisms of the somatosensory alterations.
    Journal of oral rehabilitation, 2020, Volume: 47, Issue:2

    Topics: Anesthesia, Local; Humans; Lidocaine; Pain; Pain Measurement; Pain Threshold; Temporomandibular Join

2020
Effects of intramuscular morphine in men and women with temporomandibular disorder with myofascial pain.
    Oral diseases, 2018, Volume: 24, Issue:8

    Topics: Adult; Analgesics, Opioid; Anesthetics, Local; Double-Blind Method; Facial Pain; Female; Humans; Inj

2018
Temporomandibular joint iontophoresis: a double-blind randomized clinical trial.
    Journal of orofacial pain, 1996,Spring, Volume: 10, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analysis of Variance; Anesthetics, Local; Anti-Inflammat

1996
Analysis of 50 patients with atypical odontalgia. A preliminary report on pharmacological procedures for diagnosis and treatment.
    Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics, 1998, Volume: 85, Issue:1

    Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Anesthetics, Combined; Anesthetics, Local;

1998
Intra-articular injection of hyaluronic acid reduces total amounts of leukotriene C4, 6-keto-prostaglandin F1alpha, prostaglandin F2alpha and interleukin-1beta in synovial fluid of patients with internal derangement in disorders of the temporomandibular j
    The British journal of oral & maxillofacial surgery, 1998, Volume: 36, Issue:1

    Topics: 6-Ketoprostaglandin F1 alpha; Adolescent; Adult; Anesthetics, Local; Anti-Inflammatory Agents; Arthr

1998
The effect of intra-articular irrigation injection therapy on osteoarthrosis of the temporomandibular joint.
    The Chinese journal of dental research, 1998, Volume: 1, Issue:3

    Topics: Adult; Chi-Square Distribution; Female; Humans; Injections, Intra-Articular; Lidocaine; Male; Middle

1998
Better palpation of pain: reliability and validity of a new pressure pain protocol in TMD.
    Cranio : the journal of craniomandibular practice, 2000, Volume: 18, Issue:1

    Topics: Adult; Analysis of Variance; Anesthetics, Local; Double-Blind Method; Facial Pain; Female; Humans; I

2000

Other Studies

20 other studies available for lidocaine and Temporomandibular Disorders

ArticleYear
Modified dextrose prolotherapy for recurrent temporomandibular joint dislocation.
    The British journal of oral & maxillofacial surgery, 2014, Volume: 52, Issue:1

    Topics: Adolescent; Adult; Anesthetics, Local; Female; Follow-Up Studies; Glucose Solution, Hypertonic; Huma

2014
iTMJ reduction.
    Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 2014, Volume: 151, Issue:6

    Topics: Aged; Humans; Injections, Intralesional; Injections, Intramuscular; Lidocaine; Male; Musculoskeletal

2014
Intraoperative mandibular nerve block with peripheral nerve stimulator for temporomandibular joint ankylosis.
    Journal of clinical anesthesia, 2016, Volume: 35

    Topics: Androstanols; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous; Anesthetics, L

2016
Use of masseteric and deep temporal nerve blocks for reduction of mandibular dislocation.
    Anesthesia progress, 2009,Spring, Volume: 56, Issue:1

    Topics: Aged, 80 and over; Anesthetics, Local; Female; Humans; Injections; Joint Dislocations; Lidocaine; Ma

2009
Numbness of the ear following inferior alveolar nerve block: the forgotten complication.
    British dental journal, 2009, Jul-11, Volume: 207, Issue:1

    Topics: Adult; Anesthetics, Local; Ear Auricle; Ear Diseases; Female; Humans; Hypesthesia; Lidocaine; Mandib

2009
Temporomandibular joint injection with corticosteroid and local anesthetic for limited mouth opening.
    Journal of oral science, 2011, Volume: 53, Issue:3

    Topics: Adolescent; Adult; Aged; Anesthetics, Local; Female; Glucocorticoids; Humans; Injections, Intra-Arte

2011
Evidence for the involvement of endogenous ATP and P2X receptors in TMJ pain.
    European journal of pain (London, England), 2005, Volume: 9, Issue:1

    Topics: Adenosine Triphosphate; Animals; Anti-Inflammatory Agents; Arthralgia; Arthritis; Carrageenan; Disea

2005
Methemoglobinemia--an unusual cause of intraoperative hypoxia.
    Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics, 2007, Volume: 103, Issue:2

    Topics: Administration, Topical; Adult; Aerosols; Anesthesia, Dental; Anesthetics, Combined; Anesthetics, Lo

2007
[Possibilities of the therapeutic use of electrophoresis in diseases of the temporomandibular joint].
    Fogorvosi szemle, 1981, Volume: 74, Issue:4

    Topics: Administration, Topical; Humans; Iontophoresis; Lidocaine; Muscle Relaxants, Central; Parasympatholy

1981
Effects of inflammatory irritant application to the rat temporomandibular joint on jaw and neck muscle activity.
    Pain, 1995, Volume: 60, Issue:2

    Topics: Animals; Electromyography; Female; Inflammation; Injections; Irritants; Jaw; Lidocaine; Male; Muscle

1995
Awake blind nasal intubation.
    Anaesthesia and intensive care, 1993, Volume: 21, Issue:2

    Topics: Adolescent; Anesthesia, Local; Ankylosis; Face; Humans; Intubation, Intratracheal; Lidocaine; Male;

1993
Local anesthesia does not block mustard-oil-induced temporomandibular inflammation.
    Anesthesia and analgesia, 2001, Volume: 92, Issue:4

    Topics: Anesthetics, Local; Animals; Arthritis; Bupivacaine; Dose-Response Relationship, Drug; Edema; Electr

2001
Elongated styloid process (Eagle's syndrome): a clinical study.
    Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 2002, Volume: 60, Issue:2

    Topics: Adolescent; Adult; Aged; Anesthetics, Local; Calcinosis; Deglutition Disorders; Diagnosis, Different

2002
Effect of arthrocentesis on TMJ disturbance of mouth closure with loud clicking: a preliminary study.
    Cranio : the journal of craniomandibular practice, 2002, Volume: 20, Issue:1

    Topics: Adolescent; Adult; Aged; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Arthrography;

2002
Effect of an anesthetic injected into the temporomandibular joint space in patients with TMD.
    Journal of craniomandibular disorders : facial & oral pain, 1992,Fall, Volume: 6, Issue:4

    Topics: Adolescent; Adult; Aged; Analysis of Variance; Facial Muscles; Facial Pain; Female; Humans; Injectio

1992
Long-term effect of intra-articular injections of a glucocorticosteroid into the TMJ: a clinical and radiographic 8-year follow-up.
    Journal of craniomandibular disorders : facial & oral pain, 1991,Winter, Volume: 5, Issue:1

    Topics: Adult; Aged; Arthritis, Rheumatoid; Betamethasone; Female; Follow-Up Studies; Humans; Lidocaine; Mal

1991
Iontophoresis: an effective modality for the treatment of inflammatory disorders of the temporomandibular joint and myofascial pain.
    Cranio : the journal of craniomandibular practice, 1990, Volume: 8, Issue:2

    Topics: Adult; Discitis; Epinephrine; Facial Pain; Female; Humans; Inflammation; Iontophoresis; Joint Disloc

1990
[The effect of the local anesthesia to the posterior ramus of the mandible in patients with temporomandibular joint problems].
    Shigaku = Odontology; journal of Nihon Dental College, 1990, Volume: 78, Issue:1

    Topics: Diagnosis, Differential; Facial Pain; Humans; Lidocaine; Mandible; Masticatory Muscles; Neck Muscles

1990
[Nonsurgical treatment of TMJ disorders--chemical and physical therapy].
    Zhonghua ya yi xue hui za zhi, 1987, Volume: 6, Issue:3

    Topics: Acetaminophen; Chlorzoxazone; Diazepam; Electric Stimulation Therapy; Facial Pain; Humans; Lidocaine

1987
Treatment of an acute anterior disk displacement in the temporomandibular joint. A case report.
    Physical therapy, 1987, Volume: 67, Issue:8

    Topics: Acute Disease; Aged; Dexamethasone; Female; Humans; Iontophoresis; Lidocaine; Physical Therapy Modal

1987