lidocaine has been researched along with Syncope in 49 studies
Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.
Syncope: A transient loss of consciousness and postural tone caused by diminished blood flow to the brain (i.e., BRAIN ISCHEMIA). Presyncope refers to the sensation of lightheadedness and loss of strength that precedes a syncopal event or accompanies an incomplete syncope. (From Adams et al., Principles of Neurology, 6th ed, pp367-9)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Tussive syncope is a rare condition that often responds to treatment of the underlying cause of coughing." | 5.30 | Nebulized lidocaine in the treatment of refractory tussive syncope. ( Morley, TF; Whims, LA; Zappasodi, SJ, 1998) |
| " We discuss the literature that has influenced current office behavior regarding endocarditis prophylaxis, the use of electrosurgery with pacemakers, arrhythmogenic drug interactions, vasovagal syncope, lidocaine "allergy," and bleeding complications from oral anticoagulants." | 4.79 | Medical issues and emergencies in the dermatology office. ( Fader, DJ; Johnson, TM, 1997) |
| "A 70-year-old man, on prenylamine for exertional angina, complained of syncopal attacks which seemed to be caused by bursts of ventricular tachycardia associated with Q-T prolongation." | 3.66 | Prenylamine-induced ventricular arrhythmias and syncopal attacks with Q-T prolongation. Report of a case and comment on therapeutic use of lignocaine. ( Bartolomei, C; Riccioni, N; Soldani, S, 1980) |
| "Double vision was noticed once intraoperatively (Articain) and postoperatively (Lidocain)." | 2.67 | [General complications in dental local anesthesia]. ( Hidding, J; Khoury, F, 1991) |
| "Finally, seizure-like nonepileptic disorders were reviewed and differential diagnostic points highlighted." | 2.36 | Seizures and seizure-like states in the child: an approach to emergency management. ( Oppenheimer, EY; Rosman, NP, 1983) |
| "Syncope was abolished after successful radiofrequency catheter ablation of the AFL." | 1.31 | Syncope in patients with atrial flutter during treatment with class Ic antiarrhythmic drugs. ( Azegami, K; Hiejima, K; Hirao, K; Horikawa, T; Kawabata, M; Motokawa, K; Suzuki, F; Suzuki, K, 2001) |
| "Tussive syncope is a rare condition that often responds to treatment of the underlying cause of coughing." | 1.30 | Nebulized lidocaine in the treatment of refractory tussive syncope. ( Morley, TF; Whims, LA; Zappasodi, SJ, 1998) |
| "A 28-year-old woman experienced respiratory depression and hemiplegia after the injection of a superficial trapezius trigger point." | 1.30 | Intrathecal injection: unusual complication of trigger-point injection therapy. ( Hoffman, RS; Nelson, LS, 1998) |
| "Torsade de pointes (TdP) syncopal episodes were almost invariably precipitated by emotional stress or menstruation in a 17-year-old girl." | 1.28 | Role of early afterdepolarization in familial long QTU syndrome and torsade de pointes. ( Liu, WY; Zheng, LR; Zhou, JT, 1992) |
| "Diazepam was also effective in reducing the cardiac response." | 1.26 | Changes in heart rate during administration of local anesthetics in neuropsychiatric patients. ( Nakajima, T; Yakata, H; Yokobayashi, T, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 23 (46.94) | 18.7374 |
| 1990's | 10 (20.41) | 18.2507 |
| 2000's | 8 (16.33) | 29.6817 |
| 2010's | 5 (10.20) | 24.3611 |
| 2020's | 3 (6.12) | 2.80 |
| Authors | Studies |
|---|---|
| Ola, O | 1 |
| Gharacholou, SM | 1 |
| Del-Carpio Munoz, F | 1 |
| Ke, Z | 1 |
| Li, C | 1 |
| Bai, G | 1 |
| Tan, L | 1 |
| Wang, J | 1 |
| Zhou, M | 1 |
| Zhou, J | 1 |
| Chen, SY | 1 |
| Dong, X | 1 |
| Arias, MA | 1 |
| Pachón, M | 1 |
| Loughlin, G | 1 |
| Lloyd, MG | 1 |
| Wakeling, JM | 1 |
| Koehle, MS | 1 |
| Drapala, RJ | 1 |
| Claydon, VE | 1 |
| Petit, PF | 1 |
| Hantson, P | 1 |
| Jadoul, M | 1 |
| Gillion, V | 1 |
| DeLillo, DM | 1 |
| Jesty, SA | 1 |
| Souza, MJ | 1 |
| Beyer, A | 1 |
| Ganti, B | 1 |
| Majkrzak, A | 1 |
| Theyyunni, N | 1 |
| Takaya, T | 1 |
| Okamoto, M | 1 |
| Yodoi, K | 1 |
| Hata, K | 1 |
| Kijima, Y | 1 |
| Nakajima, H | 1 |
| Nishikawa, Y | 1 |
| Kita, T | 1 |
| Ito, M | 1 |
| Seo, T | 1 |
| Kawashima, S | 1 |
| Mizobuchi, M | 1 |
| Enjoji, Y | 1 |
| Nakamura, S | 1 |
| Muranishi, H | 1 |
| Utsunomiya, M | 1 |
| Funatsu, A | 1 |
| Kobayashi, T | 1 |
| Nogami, A | 1 |
| Nakao, M | 1 |
| Kubota, S | 1 |
| Sugiyasu, A | 1 |
| Doi, H | 1 |
| Yokoyama, K | 1 |
| Yumoto, K | 1 |
| Tamaki, T | 1 |
| Kato, K | 1 |
| Hosokawa, N | 1 |
| Sagai, H | 1 |
| Nakamura, H | 1 |
| Nitta, J | 1 |
| Yamauchi, Y | 1 |
| Aonuma, K | 1 |
| Ikeda, T | 1 |
| Abe, A | 1 |
| Yusu, S | 1 |
| Nakamura, K | 1 |
| Ishiguro, H | 1 |
| Mera, H | 1 |
| Yotsukura, M | 1 |
| Yoshino, H | 1 |
| Yoshisato, T | 1 |
| Takeda, H | 1 |
| Sekiguchi, Y | 1 |
| Tsuburaya, R | 1 |
| Endo, N | 1 |
| Niitsuma, T | 1 |
| Miura, E | 1 |
| Hirosaka, A | 1 |
| Owada, K | 1 |
| Tamagawa, K | 1 |
| Bamgbade, OA | 1 |
| Surber, R | 1 |
| Hensellek, S | 1 |
| Prochnau, D | 1 |
| Werner, GS | 1 |
| Benndorf, K | 1 |
| Figulla, HR | 1 |
| Zimmer, T | 1 |
| Lew, HT | 1 |
| March, HW | 1 |
| Oppenheimer, EY | 1 |
| Rosman, NP | 1 |
| Milne, JR | 1 |
| Ward, DE | 2 |
| Spurrell, RA | 1 |
| Camm, AJ | 1 |
| Gmeiner, R | 1 |
| Ng, CK | 1 |
| Kirchmair, W | 1 |
| Hochleitner, M | 1 |
| Tamari, I | 1 |
| Rabinowitz, B | 1 |
| Neufeld, HN | 2 |
| Riccioni, N | 1 |
| Bartolomei, C | 1 |
| Soldani, S | 1 |
| Sutherland, R | 1 |
| Fader, DJ | 1 |
| Johnson, TM | 1 |
| Selcuk, E | 1 |
| Ertürk, S | 1 |
| Afrashi, A | 1 |
| Whims, LA | 1 |
| Zappasodi, SJ | 1 |
| Morley, TF | 1 |
| Nelson, LS | 1 |
| Hoffman, RS | 1 |
| Lustig, JP | 1 |
| Zusman, SP | 1 |
| Rood, JP | 1 |
| Kawabata, M | 1 |
| Hirao, K | 1 |
| Horikawa, T | 1 |
| Suzuki, K | 1 |
| Motokawa, K | 1 |
| Suzuki, F | 1 |
| Azegami, K | 1 |
| Hiejima, K | 1 |
| Yakata, H | 1 |
| Yokobayashi, T | 1 |
| Nakajima, T | 1 |
| Cass, N | 1 |
| Morgan, C | 1 |
| Verrill, PJ | 1 |
| Muir, VM | 1 |
| Leonard, M | 1 |
| Haddaway, E | 1 |
| Zhou, JT | 1 |
| Zheng, LR | 1 |
| Liu, WY | 1 |
| Waxman, MB | 1 |
| Asta, JA | 1 |
| Cameron, DA | 1 |
| Endrenyi, L | 1 |
| D'Eramo, EM | 1 |
| Hidding, J | 1 |
| Khoury, F | 1 |
| Levy, SM | 1 |
| Baker, KA | 1 |
| Cheesman, M | 1 |
| Slama, R | 1 |
| Coumel, P | 1 |
| Motte, G | 1 |
| Gourgon, R | 1 |
| Waynberger, M | 1 |
| Touche, S | 1 |
| Lyon, LJ | 1 |
| Singer, K | 1 |
| Lundberg, WB | 1 |
| Kaplinsky, E | 1 |
| Yahini, JH | 1 |
| Barzilai, J | 1 |
| McRae, JR | 1 |
| Wagner, GS | 1 |
| Rogers, MC | 1 |
| Canent, RV | 1 |
| Pomerantz, B | 1 |
| O'Rourke, RA | 1 |
| Schacher, V | 1 |
| Iranpour, B | 1 |
| Mills, J | 1 |
| Kornprobst, L | 1 |
| Sapru, RP | 1 |
| Griffiths, PH | 1 |
| Guz, A | 1 |
| Eisele, J | 1 |
| Miller, DS | 1 |
| Blount, AW | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Antipruritic Effect of Topical Ketamine, Amitriptyline, and Lidocaine[NCT03096444] | Phase 2 | 13 participants (Actual) | Interventional | 2017-05-23 | Terminated (stopped due to Efficacy was not seen after interim analysis) | ||
| Maternal-Fetal Monitoring of Patients With Rheumatic Heart Disease During Dental Procedure Under Local Anesthesia[NCT00482573] | Phase 1 | 31 participants (Actual) | Interventional | 2004-04-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
"Peak itch intensity between the vehicle and 4 other active treatments (individual ketamine, amitriptyline, or lidocaine, and KeAmLi-combo). Itch intensity was measured on a 100mm scale visual analog scale for 10 minutes. 0 was weighted with no itch and 100 was weighted with most itch imaginable." (NCT03096444)
Timeframe: 10 minutes
| Intervention | Intensity score (Mean) |
|---|---|
| Topical KeAmLi Combo | 62.7 |
| Topical Ketamine | 63.1 |
| Topical Amitriptyline | 69.2 |
| Topical Lidocaine | 65.8 |
| Topical Vehicle | 61.9 |
Assess mechanical detection and pain thresholds using von Frey filaments stimulators (measured in force mN) to calculate the final threshold as the geometric mean of five series of ascending and descending stimuli. (NCT03096444)
Timeframe: 5 minutes
| Intervention | mN (Mean) | |
|---|---|---|
| Mechanical Detection Threshold | Mechanical Pain Threshold | |
| Topical Amitriptyline | 3.573423965 | 152.4768146 |
| Topical KeAmLi Combo | 3.519376956 | 152.3293608 |
| Topical Ketamine | 3.464204768 | 135.9 |
| Topical Lidocaine | 3.546037659 | 126.9 |
| Topical Vehicle | 3.525692637 | 148.7138273 |
Two standardized quantitative sensory tests are performed to measure warmth detection threshold (assesses the threshold of which warmth sensation is first detected) and heat pain threshold (assesses the threshold at which heat pain sensation is first detected). Measured in change in celsius. (NCT03096444)
Timeframe: 3 minutes
| Intervention | Degrees celsius (Mean) | |
|---|---|---|
| Warm Detection Threshold | Heat Pain Threshold | |
| Topical Amitriptyline | 33.9 | 40.0 |
| Topical KeAmLi Combo | 33.6 | 39.8 |
| Topical Ketamine | 34.0 | 40.0 |
| Topical Lidocaine | 33.7 | 39.4 |
| Topical Vehicle | 33.8 | 39.7 |
5 reviews available for lidocaine and Syncope
| Article | Year |
|---|---|
Severe needle phobia in the perianesthesia setting.
Topics: Acute Disease; Adult; Ambulatory Surgical Procedures; Desensitization, Psychologic; Epilepsies, Part | 2007 |
Seizures and seizure-like states in the child: an approach to emergency management.
Topics: Anesthesia, General; Child; Child, Preschool; Diagnosis, Differential; Diazepam; Emergencies; Humans | 1983 |
Medical issues and emergencies in the dermatology office.
Topics: Anaphylaxis; Anesthetics, Local; Anti-Arrhythmia Agents; Anticoagulants; Cerebrovascular Disorders; | 1997 |
An adverse reaction to local anaesthesia: report of a case.
Topics: Adult; Anesthesia, Dental; Anesthesia, Local; Anesthetics, Local; Diagnostic Errors; Drug Hypersensi | 1996 |
The Stokes-Adams syndrome.
Topics: Adams-Stokes Syndrome; Adrenal Cortex Hormones; Arrhythmias, Cardiac; Atropine; Chlorothiazide; Digi | 1969 |
3 trials available for lidocaine and Syncope
| Article | Year |
|---|---|
[General complications in dental local anesthesia].
Topics: Adult; Anesthesia, Dental; Anesthesia, Local; Anesthetics, Local; Carticaine; Diplopia; Double-Blind | 1991 |
[Ventricular tachycardia and "volley of ventricular spikes". Morphological frontiers between ventricular dysrhythmias].
Topics: Cardiac Complexes, Premature; Clinical Trials as Topic; Diagnosis, Differential; Electrocardiography | 1973 |
The local anesthetic efficacy of tripelennamine hydrochloride.
Topics: Anesthesia, Dental; Anesthesia, Local; Animals; Clinical Trials as Topic; Dental Cavity Preparation; | 1967 |
41 other studies available for lidocaine and Syncope
| Article | Year |
|---|---|
Massive Discordant T-Wave Alternans and Imminent Torsades de Pointes: The "Elephant in the Room".
Topics: Anti-Arrhythmia Agents; Chest Pain; Cocaine-Related Disorders; Electrocardiography; Female; Humans; | 2021 |
KCNH2 mutation c.3099_3112del causes congenital long QT syndrome type 2 with gender differences.
Topics: ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Female; Humans; Lidocaine; Long QT Syndrom | 2023 |
New Onset Recurrent Syncope Triggered by Fever.
Topics: Amiodarone; Coronary Angiography; Drug Therapy, Combination; Electric Countershock; Electrocardiogra | 2020 |
Carotid sinus hypersensitivity: block of the sternocleidomastoid muscle does not affect responses to carotid sinus massage in healthy young adults.
Topics: Adult; Anesthetics, Local; Baroreflex; Blood Pressure; Carotid Sinus; Female; Humans; Lidocaine; Mal | 2017 |
The Case | Severe hypokalemia complicated by a syncope.
Topics: Administration, Topical; Aged, 80 and over; Benzalkonium Compounds; Drug Combinations; Electrocardio | 2018 |
Episodic syncope caused by ventricular flutter in a tiger (Panthera tigris).
Topics: Animals; Anti-Arrhythmia Agents; Lidocaine; Male; Panthera; Sotalol; Syncope; Ventricular Flutter | 2013 |
A Perfect Storm: Tyrosine Kinase Inhibitor-Associated Polymorphic Ventricular Tachycardia.
Topics: Adenine; Amiodarone; Anti-Arrhythmia Agents; Antineoplastic Agents; Cardiotonic Agents; Electric Cou | 2017 |
Torsades de Pointes with QT prolongation related to donepezil use.
Topics: Aged, 80 and over; Alzheimer Disease; Cholinesterase Inhibitors; Colitis; Donepezil; Electrocardiogr | 2009 |
Ventricular late potential in patients with apparently normal electrocardiogram; predictor of Brugada syndrome.
Topics: Adult; Aged; Aged, 80 and over; Brugada Syndrome; Chi-Square Distribution; Electrocardiography; Fema | 2010 |
Enhancement of J-ST-segment elevation by the glucose and insulin test in Brugada syndrome.
Topics: Adult; Anti-Arrhythmia Agents; Bundle-Branch Block; Electrocardiography; Glucose; Heart Arrest; Huma | 2003 |
The full stomach test as a novel diagnostic technique for identifying patients at risk of Brugada syndrome.
Topics: Adult; Brugada Syndrome; Circadian Rhythm; Electrocardiography; Electrophysiologic Techniques, Cardi | 2006 |
[Elderly Brugada syndrome with recurrent syncope, diagnosed by pilsicainide challenge test].
Topics: Aged; Brugada Syndrome; Electrocardiography; Humans; Lidocaine; Male; Recurrence; Syncope | 2007 |
Combination of cardiac conduction disease and long QT syndrome caused by mutation T1620K in the cardiac sodium channel.
Topics: Action Potentials; Adolescent; Adult; Ajmaline; Animals; Anti-Arrhythmia Agents; Bundle-Branch Block | 2008 |
Control of recurrent ventricular fibrillation by transvenous pacing in the absence of heart block.
Topics: Aged; Atropine; Electric Countershock; Heart Block; Heart Massage; Humans; Lidocaine; Male; Pacemake | 1967 |
The long QT syndrome; effects of drugs and left stellate ganglion block.
Topics: Adult; Arrhythmias, Cardiac; Autonomic Nerve Block; Child; Electrocardiography; Female; Humans; Inje | 1982 |
[Clinical and electrophysiological observations in a case of Romano-Ward syndrome ].
Topics: Adolescent; Arrhythmias, Cardiac; Electrocardiography; Female; Heart Ventricles; Humans; Lidocaine; | 1982 |
Torsade de pointes due to prenylamine controlled by lignocaine.
Topics: Aged; Angina Pectoris; Coronary Disease; Dizziness; Electrocardiography; Female; Humans; Lidocaine; | 1982 |
Prenylamine-induced ventricular arrhythmias and syncopal attacks with Q-T prolongation. Report of a case and comment on therapeutic use of lignocaine.
Topics: Aged; Electrocardiography; Heart Ventricles; Humans; Lidocaine; Male; Prenylamine; Syncope; Tachycar | 1980 |
Fit with finger block.
Topics: Anxiety; Fingers; Humans; Lidocaine; Nerve Block; Seizures; Syncope | 1993 |
Nebulized lidocaine in the treatment of refractory tussive syncope.
Topics: Aerosols; Aged; Anesthetics, Local; Cough; Humans; Lidocaine; Male; Syncope | 1998 |
Intrathecal injection: unusual complication of trigger-point injection therapy.
Topics: Administration, Topical; Adult; Anesthetics, Local; Anti-Inflammatory Agents; Drug Combinations; Fac | 1998 |
Immediate complications of local anesthetic administered to 1,007 consecutive patients.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anesthesia, Dental; Anesthesia, Local; Anesthetics, Loca | 1999 |
Adverse reaction to dental local anaesthetic injection--'allergy' is not the cause.
Topics: Anesthesia, Dental; Anesthetics, Local; Drug Hypersensitivity; Female; Humans; Immunologic Tests; In | 2000 |
Syncope in patients with atrial flutter during treatment with class Ic antiarrhythmic drugs.
Topics: Adult; Anti-Arrhythmia Agents; Atrial Flutter; Catheter Ablation; Electrocardiography; Electrophysio | 2001 |
Changes in heart rate during administration of local anesthetics in neuropsychiatric patients.
Topics: Adult; Anesthesia, Dental; Anesthesia, Local; Anti-Anxiety Agents; Autonomic Nervous System; Diazepa | 1979 |
Sensitivity to lignocaine.
Topics: Aged; Drug Hypersensitivity; Humans; Lidocaine; Male; Syncope | 1977 |
Collapse during spinal anaesthesia?
Topics: Aged; Analgesia; Anesthesia, Spinal; Humans; Lidocaine; Male; Pentobarbital; Preanesthetic Medicatio | 1978 |
Adverse reactions to local anaesthetics and vasoconstrictor drugs.
Topics: Anaphylaxis; Anesthesia, Dental; Anesthetics, Local; Arteriosclerosis; Blood Pressure; Coronary Dise | 1975 |
Morbidity following dental extraction. A comparative survey of local analgesia and general anaesthesia.
Topics: Adolescent; Adult; Age Factors; Aged; Anesthesia, Dental; Anesthesia, General; Anesthesia, Local; Ch | 1976 |
Role of early afterdepolarization in familial long QTU syndrome and torsade de pointes.
Topics: Action Potentials; Adolescent; Cardiac Pacing, Artificial; Epinephrine; Female; Heart Conduction Sys | 1992 |
Vasodepressor reaction induced by inferior vena caval occlusion and isoproterenol.
Topics: Animals; Atropine; Disease Models, Animal; Drug Administration Routes; Heart Rate; Hypotension; Infu | 1992 |
Morbidity and mortality with outpatient anesthesia: the Massachusetts experience.
Topics: Aged; Ambulatory Surgical Procedures; Anesthesia, Dental; Anesthesia, General; Anesthesia, Intraveno | 1992 |
Considerations in differential diagnosis of adverse reactions to local anesthetic: report of case.
Topics: Anesthesia, Dental; Anesthesia, Local; Diagnosis, Differential; Drug Hypersensitivity; Female; Human | 1986 |
Exacerbation of ventricular tachycardia by tocainide.
Topics: Aged; Electrocardiography; Female; Heart Ventricles; Humans; Hypotension; Lidocaine; Male; Middle Ag | 1985 |
Communications to the editor: Lidocaine for quinidine syncope.
Topics: Humans; Lidocaine; Quinidine; Syncope | 1974 |
Ventricular arrhythmias associated with the ingestion of alcohol.
Topics: Adult; Alcohol Drinking; Arrhythmias, Cardiac; Electrocardiography; Epilepsy, Tonic-Clonic; Ethanol; | 1972 |
Quinidine syncope; report of a case successfully treated with lidocaine.
Topics: Adult; Atrial Fibrillation; Electrocardiography; Female; Humans; Lidocaine; Quinidine; Syncope; Tach | 1972 |
Paroxysmal familial ventricular fibrillation.
Topics: Child; Death, Sudden; Electrocardiography; Electrophysiology; Humans; Lidocaine; Male; Propranolol; | 1974 |
[Can everything be foreseen? An exceptional case of fatal syncope during local anesthesia].
Topics: Anesthesia, Local; Female; France; Humans; Lidocaine; Malpractice; Surgery, Plastic; Syncope | 1970 |
Syncope on swallowing.
Topics: Adult; Atropine; Deglutition; Electrocardiography; Female; Heart Block; Humans; Lidocaine; Reflex, A | 1971 |
Quinidine-induced recurrent ventricular fibrillation: (quinidine syncope) treated with transvenous pacemaker.
Topics: Adult; Atrial Fibrillation; Atropine; Blood Cell Count; Chlorpromazine; Coumarins; Creatine Kinase; | 1971 |