Page last updated: 2024-10-28

lidocaine and Sterility, Female

lidocaine has been researched along with Sterility, Female in 13 studies

Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.

Research Excerpts

ExcerptRelevanceReference
"We found no difference in pain between the intrauterine-lidocaine and placebo groups."9.11The use of intrauterine lidocaine to minimize pain during hysterosalpingography: a randomized trial. ( Frishman, GN; Plosker, S; Shafi, F; Spencer, PK; Weitzen, S, 2004)
"We found no difference in pain between the intrauterine-lidocaine and placebo groups."5.11The use of intrauterine lidocaine to minimize pain during hysterosalpingography: a randomized trial. ( Frishman, GN; Plosker, S; Shafi, F; Spencer, PK; Weitzen, S, 2004)
"Postoperative pain was evaluated with the use of a visual analog scale with scores ranging from 1-10 immediately after surgery and over the next 48 hours."2.69Postoperative pain control after microlaparoscopy in patients with infertility: a prospective randomized study. ( Di Carlo, C; Nappi, C; Pellicano, M; Zullo, F; Zupi, E, 1998)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19905 (38.46)18.7374
1990's2 (15.38)18.2507
2000's4 (30.77)29.6817
2010's2 (15.38)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Liu, Y1
Pan, L1
Wang, Y1
Chauhan, MB1
Lakra, P1
Jyotsna, D1
Nanda, S1
Malhotra, V1
FORTUNA, A1
Parsanezhad, ME1
Lahsaee, M1
Alborzi, S1
Vafaei, H1
Schmidt, EH1
Lam, KW1
Pun, TC1
Ng, EH1
Wong, KS1
Frishman, GN1
Spencer, PK1
Weitzen, S1
Plosker, S1
Shafi, F1
Edelstam, GA2
Andersson, E1
Rådestad, A1
Flam, F1
Gottlieb, C1
Pellicano, M1
Zullo, F1
Di Carlo, C1
Zupi, E1
Nappi, C1
Sjösten, AC1
Salamon, CW1
Kaba, H1
Rosser, A1
Keverne, B1
Hofmeister, FJ1
Dass, A1
Jain, A1
Dhawan, S1
Joseph, AA1
Kincl, FA1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Effect of Intracervical Lidocaine Versus Intramuscular Diclofenac for Pain Relief During Hysterosalpingography Among Infertile Women In A Tertiary Hospital In Kano: A Randomized Controlled Trial[NCT02918812]Phase 4140 participants (Anticipated)Interventional2016-09-30Recruiting
Evaluation of Aerosolized Bupivacaine Versus Pre-incision Lidocaine Versus Instilled Liquid Bupivacaine Versus Post-operative Bupivacaine Injection for Optimization of Post-operative Pain Control in Laparoscopic Bariatric Surgical Patients[NCT00508976]Phase 2100 participants (Actual)Interventional2007-06-30Completed
Double Blind, Randomized, Prospective Trial of Impact of Pain Scores on Intrauterine Lidocaine vs Normal Saline Infusion Before IUD Placement.[NCT01311102]Phase 440 participants (Actual)Interventional2008-07-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Pain During IUD Placement

"IUD was inserted following the manufacturer's instructions, and a pain score was immediately obtained. Pain was scored on 0-9 scale; with 0 being no pain and 9 being worst pain in life." (NCT01311102)
Timeframe: Immediately after IUD placement

Interventionunits on a scale of 0-9 (Mean)
Lidocaine2.95
Normal Saline3.68

Pain During Tenaculum Placement

"Pain score on 0-9 scale for tenaculum placement (without anesthesia); with 0 being no pain and 9 being worst pain in life. Taken to adjust for different pain thresholds among subjects" (NCT01311102)
Timeframe: Immediately following tenaculum placement

Interventionunits on a scale of 0-9 (Mean)
Lidocaine2.20
Normal Saline2.70

Pain Measurement During Liquid Infusion/Sounding

"After liquid infused into three parts of the endometrial cavity: in the lower one third, the middle, and at the top of the cavity. Pain was scored on a 0-9 scale; with 0 being no pain and 9 being worst pain in life." (NCT01311102)
Timeframe: Recorded at the end of the infusion

Interventionunits on a scale of 0-9 (Mean)
Lidocaine2.50
Normal Saline3.39

Pain Scores During Overall IUD Placement

"Pain score on 0-9 scale obtained just before the patient left the examination room; with 0 being no pain and 9 being worst pain in life." (NCT01311102)
Timeframe: Before patient left the examination room at conclusion of procedure

Interventionunits on a scale of 0-9 (Mean)
Lidocaine2.12
Normal Saline1.73

Trials

7 trials available for lidocaine and Sterility, Female

ArticleYear
[Effects of the combined therapy of heat sensitive moxibustion and acupoint injection on endometrial receptivity of hypdrosalphinx infertility in the patients after hysteroscopy and laparoscopy].
    Zhongguo zhen jiu = Chinese acupuncture & moxibustion, 2018, Jan-12, Volume: 38, Issue:1

    Topics: Acupuncture Points; Amikacin; Cefoxitin; Combined Modality Therapy; Female; Hot Temperature; Humans;

2018
Pain relief during hysterosalpingography: role of intracervical block.
    Archives of gynecology and obstetrics, 2013, Volume: 287, Issue:1

    Topics: Adult; Analgesia; Analgesics; Anesthetics, Local; Cervix Uteri; Fallopian Tube Patency Tests; Female

2013
Comparative, double-blind, randomized, placebo-controlled trial of intraperitoneal of bupivacaine and lidocaine for pain control after diagnostic laparoscopy.
    The Journal of the American Association of Gynecologic Laparoscopists, 2003, Volume: 10, Issue:3

    Topics: Adult; Anesthetics, Local; Bupivacaine; Double-Blind Method; Female; Humans; Infertility, Female; In

2003
Efficacy of preemptive analgesia for wound pain after laparoscopic operations in infertile women: a randomised, double-blind and placebo control study.
    BJOG : an international journal of obstetrics and gynaecology, 2004, Volume: 111, Issue:4

    Topics: Adult; Anesthetics, Local; Double-Blind Method; Female; Humans; Infertility, Female; Laparoscopy; Li

2004
The use of intrauterine lidocaine to minimize pain during hysterosalpingography: a randomized trial.
    Obstetrics and gynecology, 2004, Volume: 103, Issue:6

    Topics: Adult; Anesthetics, Local; Double-Blind Method; Female; Humans; Hysterosalpingography; Infertility,

2004
Postoperative pain control after microlaparoscopy in patients with infertility: a prospective randomized study.
    Fertility and sterility, 1998, Volume: 70, Issue:2

    Topics: Adult; Anesthetics, Local; Bupivacaine; Female; Humans; Infertility, Female; Injections, Intraperito

1998
Pertubation with lignocaine--a possible new treatment for women with endometriosis and impaired fertility.
    Upsala journal of medical sciences, 2001, Volume: 106, Issue:1

    Topics: Adult; Anesthetics, Local; Dose-Response Relationship, Drug; Endometriosis; Female; Humans; Infertil

2001

Other Studies

6 other studies available for lidocaine and Sterility, Female

ArticleYear
[Medical therapy of tubal obstructions].
    Quaderni di clinica ostetrica e ginecologica, 1962, Volume: 17

    Topics: Animals; Anti-Bacterial Agents; Antibiotics, Antitubercular; Fallopian Tube Diseases; Fallopian Tube

1962
The effect of lignocaine on sperm phagocytosis in the peritoneal fluid from women with or without endometriosis.
    Human reproduction (Oxford, England), 1998, Volume: 13, Issue:5

    Topics: Adult; Ascitic Fluid; Case-Control Studies; Cell Survival; Endometriosis; Female; Humans; In Vitro T

1998
Neural basis of olfactory memory in the context of pregnancy block.
    Neuroscience, 1989, Volume: 32, Issue:3

    Topics: Amygdala; Animals; Central Nervous System; Female; Infertility, Female; Lidocaine; Male; Memory; Mic

1989
Culdotomy: a method of evaluating the pelvis.
    American journal of obstetrics and gynecology, 1974, May-01, Volume: 119, Issue:1

    Topics: Anesthesia, General; Anesthesia, Local; Biopsy; Castration; Douglas' Pouch; Female; Genital Diseases

1974
Hysterosalpingography versus tubal insufflation in sterility.
    Journal of obstetrics and gynaecology of India, 1973, Volume: 23, Issue:3

    Topics: Betamethasone; Fallopian Tubes; Female; Fluoroscopy; Humans; Hydrocortisone; Hysterosalpingography;

1973
Toxic and antifertility effects of quinacrine hydrochloride in rats.
    American journal of obstetrics and gynecology, 1974, Aug-01, Volume: 119, Issue:7

    Topics: Animals; Atrophy; Autopsy; Colonic Diseases; Dose-Response Relationship, Drug; Drug Synergism; Embry

1974