Page last updated: 2024-10-28

lidocaine and Spasm

lidocaine has been researched along with Spasm in 46 studies

Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.

Spasm: An involuntary contraction of a muscle or group of muscles. Spasms may involve SKELETAL MUSCLE or SMOOTH MUSCLE.

Research Excerpts

ExcerptRelevanceReference
"To investigate the possible advantage of topical lidocaine and intravenous midazolam in preventing spasm and pain related to the radial artery."9.69Topical Lidocaine And Or/ Intravenous Midazolam Before Radial Coronary Angiography To Prevent Radial Artery Spasm. ( Elattar, MM; Haseeb, WA; NBiomy, R; Salama, MK, 2023)
"Topical lidocaine is an effective and safe method for suppressing colorectal spasm during colonoscopy (UMIN000024733)."9.30Inhibitory effect of lidocaine on colonic spasm during colonoscopy: A multicenter double-blind, randomized controlled trial. ( Aizawa, M; Fujita, T; Hewett, DG; Iwaki, T; Katsuki, S; Matsuda, T; Mori, H; Nemoto, D; Suzuki, S; Takeuchi, Y; Togashi, K; Uraoka, T, 2019)
"The effect of topical administration of 2 or 20% lidocaine and of 3% pentobarbital on traumatic vasospasm was studied in the central ear artery of the rabbit."7.68Modulatory effects of topically administered lidocaine and pentobarbital on traumatic vasospasm in the rabbit ear artery. ( Gerdin, B; Wadström, J, 1991)
"Significant improvement in symptoms of disabling cramps and muscle spasms was obtained in 9 patients with motor neuron diseases, tetany, and myotonic disorders who were treated with tocainide, a lidocaine analog."7.68Tocainide therapy in muscle cramps and spasms due to neuromuscular disease. ( Bertorini, TE; Puniani, TS, 1991)
"To investigate the possible advantage of topical lidocaine and intravenous midazolam in preventing spasm and pain related to the radial artery."5.69Topical Lidocaine And Or/ Intravenous Midazolam Before Radial Coronary Angiography To Prevent Radial Artery Spasm. ( Elattar, MM; Haseeb, WA; NBiomy, R; Salama, MK, 2023)
"Topical lidocaine is an effective and safe method for suppressing colorectal spasm during colonoscopy (UMIN000024733)."5.30Inhibitory effect of lidocaine on colonic spasm during colonoscopy: A multicenter double-blind, randomized controlled trial. ( Aizawa, M; Fujita, T; Hewett, DG; Iwaki, T; Katsuki, S; Matsuda, T; Mori, H; Nemoto, D; Suzuki, S; Takeuchi, Y; Togashi, K; Uraoka, T, 2019)
"We report a case of acute myocardial infarction (AMI) occurring after a local injection of lidocaine."5.22Acute myocardial infarction after a local anesthetic procedure in a middle-aged patient. ( Chen, M; He, S; Li, G; Liu, J; Xiao, L; Zheng, Y, 2022)
"We report two female infants with early myoclonic encephalopathy (EME) whose intractable focal seizures were suppressed with lidocaine and carbamazepine (CBZ)."3.79Successful treatment of early myoclonic encephalopathy using lidocaine and carbamazepine. ( Kobayashi, K; Kodani, N; Maniwa, S; Nakano, K; Ohtsuka, Y, 2013)
"Lidocaine has been used as an injection or spray solution to protect spasm reaction during tracheal intubation and bronchoscopy."3.76Effects of lidocaine on rat's isolated tracheal smooth muscle. ( Chu, YH; Kao, CH; Wang, HW, 2010)
"5- year-old girl with systemic lidocaine toxicity following treatment for postoperative bladder spasms."3.70Lidocaine toxicity secondary to postoperative bladder instillation in a pediatric patient. ( Cilento, BG; Clapp, CR; Poss, WB, 1999)
"The effect of topical administration of 2 or 20% lidocaine and of 3% pentobarbital on traumatic vasospasm was studied in the central ear artery of the rabbit."3.68Modulatory effects of topically administered lidocaine and pentobarbital on traumatic vasospasm in the rabbit ear artery. ( Gerdin, B; Wadström, J, 1991)
"Significant improvement in symptoms of disabling cramps and muscle spasms was obtained in 9 patients with motor neuron diseases, tetany, and myotonic disorders who were treated with tocainide, a lidocaine analog."3.68Tocainide therapy in muscle cramps and spasms due to neuromuscular disease. ( Bertorini, TE; Puniani, TS, 1991)
"Oromandibular dystonia (OMD) is a focal dystonia manifested by involuntary masticatory and/or lingual muscle contractions."1.31Factors influencing the therapeutic effect of muscle afferent block for oromandibular dystonia and dyskinesia: implications for their distinct pathophysiology. ( Iizuka, T; Kaji, R; Shibasaki, H; Yoshida, K, 2002)
"Vasospasm is known to be present during most microvascular procedures."1.27Experimental vasospasm. ( Seaber, AV, 1987)

Research

Studies (46)

TimeframeStudies, this research(%)All Research%
pre-199025 (54.35)18.7374
1990's7 (15.22)18.2507
2000's6 (13.04)29.6817
2010's6 (13.04)24.3611
2020's2 (4.35)2.80

Authors

AuthorsStudies
Xiao, L1
Liu, J1
Li, G1
Zheng, Y1
Chen, M1
He, S1
Elattar, MM1
NBiomy, R1
Haseeb, WA1
Salama, MK1
Nemoto, D1
Suzuki, S1
Mori, H1
Katsuki, S1
Iwaki, T1
Aizawa, M1
Takeuchi, Y1
Uraoka, T1
Matsuda, T1
Fujita, T1
Hewett, DG1
Togashi, K1
Nakano, K1
Kobayashi, K1
Maniwa, S1
Kodani, N1
Ohtsuka, Y1
Hebard, RL1
Ouadhour, A1
Sideris, G1
Smida, W1
Logeart, D1
Stratiev, V1
Henry, P1
Kao, CH1
Chu, YH1
Wang, HW1
Glück, J1
Rymarczyk, B1
Rogala, B1
Saçak, B1
Sirinoğlu, H1
Yoshida, K1
Kaji, R1
Shibasaki, H1
Iizuka, T1
Azma, T1
Okida, M1
FUNKQUIST, B1
OBEL, N1
CALLAHAN, A1
MIYABE, I1
SUGIYAMA, S1
KIMURA, S1
NAKAZAWA, A1
FURUYA, M1
HOSOGAWA, A1
KOBAYASHI, Y1
Langford, CF1
Udvari Nagy, S1
Ghoniem, GM1
Roy, N1
Smith, ME1
Allen, B1
Merrill, RM1
Urban, BJ1
McDonald, HP1
Steen, SN1
Bouche, J1
Frèche, C1
Fombeur, JP1
Achard, M1
Jessop, J1
Beinart, C1
Sos, TA1
Saddekni, S1
Weiner, MA1
Sniderman, KW1
Cunningham, E1
Korbon, GA1
Crabb, IJ1
Allan, L1
Latvala, K1
Clapp, CR1
Poss, WB1
Cilento, BG1
Kang, YM1
Choi, WS1
Pickar, JG1
Ben-Menachem, Y1
Dosseh, MB1
Dupiot, M1
Guèye, MS1
Cibils, LA1
Santonja-Lucas, JJ1
Roper, B1
Paul, AS1
Davies, DR1
Haines, JF1
Wadström, J1
Gerdin, B1
Puniani, TS1
Bertorini, TE1
Wendt, JR1
Seaber, AV1
Wisborg, T1
Jørgensen, BC1
Leicht, BP1
Sadat-Ali, M1
Chowdhary, UM1
Mohanna, M1
Brismar, J1
Geter, RK1
Winters, RR1
Puckett, CL1
Osguthorpe, JD1
Adkins, WY1
Robertson, JT1
Sakabe, T1
Kindt, GW1
Hudson, JS1
Gosh, HH1
Gabrielsen, TO1
Ferris, EJ1
Athanasoulis, CA1
Shapiro, JH1
Duffield, R1
Stern, MB1
Lane, CS1
Sachs, D1
Klos, I1
Gregory, JE1
Bentley, GA1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Assessment Of Pain Subsidence And Sexual Function Amelioration Using Either Pelvic Rehabilitation Or Trigger Point Injections[NCT02022722]Phase 436 participants (Anticipated)Interventional2013-08-31Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for lidocaine and Spasm

ArticleYear
Acute myocardial infarction after a local anesthetic procedure in a middle-aged patient.
    The American journal of the medical sciences, 2022, Volume: 364, Issue:1

    Topics: Anesthetics, Local; Anti-Arrhythmia Agents; Coronary Angiography; Electrocardiography; Humans; Lidoc

2022
Cerebral arterial spasm: current concepts.
    Clinical neurosurgery, 1974, Volume: 21

    Topics: Anesthesia, General; Animals; Blood Coagulation; Blood Platelets; Brain; Catecholamines; Cerebral Ar

1974
[Central effect of local anesthetics].
    Masui. The Japanese journal of anesthesiology, 1974, Volume: 23, Issue:12

    Topics: Anesthetics, Local; Animals; Brain; Diazepam; Dogs; Electroencephalography; Lidocaine; Spasm

1974

Trials

5 trials available for lidocaine and Spasm

ArticleYear
Topical Lidocaine And Or/ Intravenous Midazolam Before Radial Coronary Angiography To Prevent Radial Artery Spasm.
    JPMA. The Journal of the Pakistan Medical Association, 2023, Volume: 73(Suppl 4), Issue:4

    Topics: Cardiac Catheterization; Coronary Angiography; Female; Humans; Lidocaine; Male; Midazolam; Pain; Per

2023
Inhibitory effect of lidocaine on colonic spasm during colonoscopy: A multicenter double-blind, randomized controlled trial.
    Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society, 2019, Volume: 31, Issue:2

    Topics: Administration, Topical; Adult; Aged; Anesthetics, Local; Colonoscopy; Colorectal Neoplasms; Double-

2019
Usefulness of subcutaneous nitrate for radial access.
    Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2008, Sep-01, Volume: 72, Issue:3

    Topics: Aged; Anesthetics, Local; Cardiac Catheterization; Double-Blind Method; Feasibility Studies; Female;

2008
Levator ani trigger point injections: An underutilized treatment for chronic pelvic pain.
    Neurourology and urodynamics, 2007, Volume: 26, Issue:1

    Topics: Adult; Aged; Anesthetics, Local; Anti-Inflammatory Agents; Anus Diseases; Bupivacaine; Chronic Disea

2007
[Preventive use of lignocaine against laryngeal spasm after extubation].
    Ugeskrift for laeger, 1986, Jun-16, Volume: 148, Issue:25

    Topics: Anesthesia, General; Child; Child, Preschool; Clinical Trials as Topic; Double-Blind Method; Female;

1986

Other Studies

38 other studies available for lidocaine and Spasm

ArticleYear
Successful treatment of early myoclonic encephalopathy using lidocaine and carbamazepine.
    Epileptic disorders : international epilepsy journal with videotape, 2013, Volume: 15, Issue:3

    Topics: Anesthetics, Local; Anticonvulsants; Brain; Carbamazepine; Electroencephalography; Epilepsy, Tonic-C

2013
iTMJ reduction.
    Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 2014, Volume: 151, Issue:6

    Topics: Aged; Humans; Injections, Intralesional; Injections, Intramuscular; Lidocaine; Male; Musculoskeletal

2014
Effects of lidocaine on rat's isolated tracheal smooth muscle.
    European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2010, Volume: 267, Issue:5

    Topics: Anesthetics, Local; Animals; Bronchoscopy; Intubation, Intratracheal; Lidocaine; Muscle, Smooth; Rat

2010
An immediate hypersensitivity reaction caused by tolperisone hydrochloride.
    Journal of investigational allergology & clinical immunology, 2011, Volume: 21, Issue:5

    Topics: Drug Hypersensitivity; Edema; Erythema; Humans; Lidocaine; Male; Middle Aged; Muscle Relaxants, Cent

2011
A new and useful method to prevent spasm of microvascular anastomosis in the postoperative period.
    Microsurgery, 2012, Volume: 32, Issue:6

    Topics: Anastomosis, Surgical; Catheters; Free Tissue Flaps; Humans; Lidocaine; Microsurgery; Postoperative

2012
Factors influencing the therapeutic effect of muscle afferent block for oromandibular dystonia and dyskinesia: implications for their distinct pathophysiology.
    International journal of oral and maxillofacial surgery, 2002, Volume: 31, Issue:5

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analysis of Variance; Anesthetics, Local; Central Nervou

2002
Does lidocaine provoke clinically significant vasospasm?
    Acta anaesthesiologica Scandinavica, 2003, Volume: 47, Issue:9

    Topics: Aged; Anesthetics, Local; Female; Humans; Lidocaine; Middle Aged; Spasm; Vasoconstriction

2003
Tonic muscle spasms and blood pressure changes following the subarachnoid injection of contrast media. An experimental study in dogs with injection of Kontrast U and mixtures of Kontrast U and Xylocaine.
    Acta radiologica, 1960, Volume: 53

    Topics: Animals; Blood Pressure; Contrast Media; Dogs; Injections; Lidocaine; Muscles; Spasm

1960
BLEPHAROSPASM WITH RESECTION OF PART OF ORBICULARIS NERVE SUPPLY. CORRECTION OF INTRACTABLE CASES.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1963, Volume: 70

    Topics: Anesthesia; Anesthesia, Local; Blepharospasm; Eyelids; Facial Nerve; Humans; Keratoconjunctivitis; L

1963
[CASE OF SUCCESSFUL TREATMENT OF SHOCK IN TONSILLECTOMY AND MEASURES FOR PREVENTING IT].
    Jibi inkoka Otolaryngology, 1963, Volume: 35

    Topics: Blood Sedimentation; Blood Transfusion; Caffeine; Cyanosis; Drug Hypersensitivity; Electrocardiograp

1963
[5 RECENT CASES OF LOCAL ANESTHETIC TOXICITY IN TONSILLECTOMY].
    Jibi inkoka Otolaryngology, 1963, Volume: 35

    Topics: Anesthesia, Local; Anesthetics, Local; Child; Cocaine; Drug Hypersensitivity; Lidocaine; Pharmacolog

1963
Adductor spasmodic dysphonia versus muscle tension dysphonia: examining the diagnostic value of recurrent laryngeal nerve lidocaine block.
    The Annals of otology, rhinology, and laryngology, 2007, Volume: 116, Issue:3

    Topics: Adult; Aged; Anesthetics, Local; Autonomic Nerve Block; Diagnosis, Differential; Female; Humans; Inj

2007
Axillary block and dialysis.
    JAMA, 1967, Mar-20, Volume: 199, Issue:12

    Topics: Adolescent; Adult; Arteriovenous Fistula; Autonomic Nerve Block; Brachial Plexus; Female; Humans; In

1967
[Facial hemispasm].
    Annales d'oto-laryngologie et de chirurgie cervico faciale : bulletin de la Societe d'oto-laryngologie des hopitaux de Paris, 1967, Volume: 84, Issue:9

    Topics: Adult; Aged; Ethanol; Facial Paralysis; Female; Humans; Lidocaine; Male; Middle Aged; Spasm

1967
Muscle spasms associated with Sudeck's atrophy after injury.
    British medical journal (Clinical research ed.), 1984, Feb-25, Volume: 288, Issue:6417

    Topics: Anesthesia, Local; Humans; Lidocaine; Reflex Sympathetic Dystrophy; Spasm

1984
Arterial spasm during renal angioplasty.
    Radiology, 1983, Volume: 149, Issue:1

    Topics: Adolescent; Adult; Aged; Angioplasty, Balloon; Arterial Occlusive Diseases; Arteriosclerosis; Child;

1983
Venospasm preventing peripheral venous access.
    Anesthesiology, 1983, Volume: 59, Issue:2

    Topics: Catheterization; Child; Humans; Infusions, Parenteral; Lidocaine; Male; Muscle Spasticity; Spasm; Va

1983
Opisthotonus and hysteria.
    Anaesthesia, 1993, Volume: 48, Issue:5

    Topics: Adult; Analgesia, Epidural; Back Pain; Female; Humans; Hysteria; Lidocaine; Spasm

1993
[Paraspinal muscle spasm].
    Duodecim; laaketieteellinen aikakauskirja, 1996, Volume: 112, Issue:17

    Topics: Accidental Falls; Adolescent; Female; Humans; Lidocaine; Lumbosacral Region; Muscle, Skeletal; Pain;

1996
Lidocaine toxicity secondary to postoperative bladder instillation in a pediatric patient.
    Urology, 1999, Volume: 53, Issue:6

    Topics: Administration, Intravesical; Anesthetics; Child, Preschool; Female; Humans; Lidocaine; Postoperativ

1999
Electrophysiologic evidence for an intersegmental reflex pathway between lumbar paraspinal tissues.
    Spine, 2002, Feb-01, Volume: 27, Issue:3

    Topics: Action Potentials; Afferent Pathways; Anesthetics, Local; Animals; Cats; Electric Stimulation; Elect

2002
Paradoxic response to intraarterial lidocaine analgesia.
    AJR. American journal of roentgenology, 1978, Volume: 130, Issue:2

    Topics: Adult; Analgesia; Blood Vessels; Humans; Injections, Intra-Arterial; Lidocaine; Male; Spasm

1978
[Apropos of a severe complication of local anesthesia using xylocaine].
    Bulletin de la Societe medicale d'Afrique noire de langue francaise, 1977, Volume: 22, Issue:3

    Topics: Adult; Anesthesia, Dental; Anesthetics, Local; Drug Hypersensitivity; Female; Hiccup; Humans; Lidoca

1977
Clinical significance of fetal heart rate patterns during labor. III. Effect of paracervical block anesthesia.
    American journal of obstetrics and gynecology, 1978, Jan-01, Volume: 130, Issue:1

    Topics: Adult; Anesthesia, Local; Anesthesia, Obstetrical; Anesthetics, Local; Arteries; Cervix Uteri; Femal

1978
Evaluation of spasticity.
    The Hand, 1975, Volume: 7, Issue:1

    Topics: Cerebrovascular Disorders; Contracture; Diagnosis, Differential; Follow-Up Studies; Humans; Lidocain

1975
Surgical treatment of adult trigger finger under local anaesthetic: the method of choice?
    Journal of the Royal College of Surgeons of Edinburgh, 1992, Volume: 37, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Anesthesia, Local; Female; Fingers; Humans; Lidocaine; Male; Middle

1992
Modulatory effects of topically administered lidocaine and pentobarbital on traumatic vasospasm in the rabbit ear artery.
    British journal of plastic surgery, 1991, Volume: 44, Issue:5

    Topics: Animals; Arteries; Constriction; Ear; Female; Lidocaine; Male; Pentobarbital; Rabbits; Spasm; Time F

1991
Tocainide therapy in muscle cramps and spasms due to neuromuscular disease.
    Muscle & nerve, 1991, Volume: 14, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Electromyography; Female; Humans; Lidocaine; Male; Middle Aged; Musc

1991
Prevention of arterial spasm with transcutaneous catheters.
    Plastic and reconstructive surgery, 1990, Volume: 86, Issue:5

    Topics: Adult; Arteries; Catheters, Indwelling; Hand Injuries; Humans; Lidocaine; Male; Spasm

1990
Experimental vasospasm.
    Microsurgery, 1987, Volume: 8, Issue:4

    Topics: Animals; Electromagnetic Phenomena; Lidocaine; Microsurgery; Muscles; Papaverine; Parasympatholytics

1987
Drug-induced arterial spasm relieved by lidocaine. Case report.
    Acta chirurgica Scandinavica, 1986, Volume: 152

    Topics: Adult; Angiography; Arteries; Humans; Injections, Intra-Arterial; Lidocaine; Male; Muscle, Smooth, V

1986
Resolution of experimental microvascular spasm and improvement in anastomotic patency by direct topical agent application.
    Plastic and reconstructive surgery, 1986, Volume: 77, Issue:1

    Topics: Administration, Topical; Animals; Chlorpromazine; Disease Models, Animal; Drug Evaluation; Epinephri

1986
Carotid arteriospasm.
    The Laryngoscope, 1985, Volume: 95, Issue:8

    Topics: Adult; Branchioma; Carotid Artery Diseases; Cerebrovascular Disorders; Coma; Female; Head and Neck N

1985
Relief of arterial spasm associated with cerebral aneurysms.
    European neurology, 1972, Volume: 8, Issue:1

    Topics: Animals; Cerebral Angiography; Cerebral Arterial Diseases; Cerebrovascular Circulation; Haplorhini;

1972
Pharmacological aspects of intracerebral spasm secondary to cerebral hemorrhage. Experimental observations.
    Radiology, 1970, Volume: 95, Issue:3

    Topics: Animals; Carotid Arteries; Cerebral Angiography; Cerebrovascular Disorders; Femoral Vein; Haplorhini

1970
Iatrogenic pneumothorax. A report of three cases.
    Clinical orthopaedics and related research, 1972, Volume: 84

    Topics: Adult; Aged; Back; Female; Humans; Iatrogenic Disease; Injections, Intramuscular; Lidocaine; Muscles

1972
[Lysis of mechanically produced spasms of small arteries through local drug administration].
    Zeitschrift fur experimentelle Chirurgie, 1971, Volume: 4, Issue:5

    Topics: Animals; Chlorpromazine; Disease Models, Animal; Lidocaine; Rabbits; Renal Artery; Spasm; Vascular D

1971
The peristaltic reflex in the isolated guinea-pig ileum during drug-induced spasm of the longitudinal muscle.
    The Australian journal of experimental biology and medical science, 1968, Volume: 46, Issue:1

    Topics: Acetylcholine; Amphetamine; Animals; Electromyography; Female; Guanethidine; Guinea Pigs; Hexamethon

1968