Page last updated: 2024-10-28

lidocaine and Sinusitis

lidocaine has been researched along with Sinusitis in 15 studies

Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.

Sinusitis: Inflammation of the NASAL MUCOSA in one or more of the PARANASAL SINUSES.

Research Excerpts

ExcerptRelevanceReference
"Background Postoperative nausea and vomiting (PONV) are among the most common unpleasant and distressing adverse events following surgery under general anesthesia."2.87The Role of Endoscopic Sphenopalatine Ganglion Block on Nausea and Vomiting After Sinus Surgery. ( Abubaker, AK; Al-Qudah, MA, 2018)
"Bupivacaine help the lower pain values and less additional painkiller need after FESS."2.82Different anesthetic agents-soaked sinus packings on pain management after functional endoscopic sinus surgery: which is the most effective? ( Arıkan, OK; Haytoğlu, S; Kuran, G; Muluk, NB, 2016)
"Transient abducens nerve palsy rarely occurs after an intranasal sphenopalatine nerve block."1.34Transient abducens nerve palsy during endoscopic sinus surgery: report of three cases. ( Kim, HD; Lim, SC, 2007)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19903 (20.00)18.7374
1990's1 (6.67)18.2507
2000's3 (20.00)29.6817
2010's6 (40.00)24.3611
2020's2 (13.33)2.80

Authors

AuthorsStudies
Garzaro, M1
Dell'Era, V1
Rosa, MS1
Cerasuolo, M1
Garzaro, G1
Aluffi Valletti, P1
Tangbumrungtham, N1
Hwang, PH1
Maul, X1
Borchard, NA1
Dholakia, SS1
Patel, ZM1
Nayak, JV1
Choby, G1
Abubaker, AK1
Al-Qudah, MA1
Valdes, CJ1
Al Badaai, Y1
Bogado, M1
Samaha, M1
Haytoğlu, S1
Kuran, G1
Muluk, NB1
Arıkan, OK1
Mishra, AK1
Sinha, VR1
Nilakantan, A1
Singh, DK1
Schechtman, SA1
Wertz, AP1
Shanks, A1
Thompson, A1
Tremper, K1
Pynnonen, MA1
Healy, DW1
Koo Ng, NK1
Young, D1
McGarry, GW1
Landis, BN1
Beghetti, M1
Morel, DR1
Giger, R1
Rimensberger, PC1
Lacroix, JS1
RAJKA, G1
SKOG, E1
EL-BARBARY, A1
BOTROS, KM1
Kim, HD1
Lim, SC1
Cohen-Kerem, R1
Brown, S1
Villaseñor, LV1
Witterick, I1
Poliakova, TS1
Luchikhin, LA1
Goncharova, MV1
Shubin, MN1
Paulose, KO1
al Khalifa, S1
Shenoy, P1
Sharma, RK1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effects of Adrenaline Infiltration on Surgical Field of View in Endoscopic Sinus Surgery[NCT05867342]Phase 440 participants (Actual)Interventional2017-05-12Completed
The Effect of Local Anesthesia With Lidocaine During Insertion and Removal of Nasal Packing[NCT04519463]Early Phase 160 participants (Anticipated)Interventional2020-09-30Not yet recruiting
Does the Use of Bupivacaine Soaked Vaginal Packing Following Vaginal Surgery Decrease Postoperative Pain?[NCT03266926]140 participants (Actual)Observational [Patient Registry]2017-02-01Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Duration of Surgery

(NCT05867342)
Timeframe: intraoperatively (up to 3 hours)

Interventionminutes (Mean)
1:1000 Epinephrine Plus Saline72.05
1:1000 Epinephrine Plus Infiltration of 1% Lidocaine With 1:100,000 Epinephrine54.23

Estimated Blood Loss During Surgery

(NCT05867342)
Timeframe: intraoperatively (up to 3 hours)

InterventionmL (Mean)
1:1000 Epinephrine Plus Saline95.25
1:1000 Epinephrine Plus Infiltration of 1% Lidocaine With 1:100,000 Epinephrine91.63

Number of Days With Postoperative Bloody Nasal Discharge

Participants indicated number of days with bloody nasal discharge postoperatively using the 1-week postoperative bleeding questionnaire. (NCT05867342)
Timeframe: 1 week after the surgery (up to 2 minutes to complete assessment)

Interventiondays (Mean)
1:1000 Epinephrine Plus Saline2.85
1:1000 Epinephrine Plus Infiltration of 1% Lidocaine With 1:100,000 Epinephrine2.73

Number of Extra Pledgets Used

A pledget is a small wad of absorbent material used to stop bleeding. (NCT05867342)
Timeframe: intraoperatively (up to 3 hours)

Interventionpledgets (Mean)
1:1000 Epinephrine Plus Saline3.25
1:1000 Epinephrine Plus Infiltration of 1% Lidocaine With 1:100,000 Epinephrine2.63

Number of Nostrils With Continuous Fresh Bleeding

Number of nostrils with excessive fresh bleeding postoperatively using the 1-week postoperative bleeding questionnaire. Continuous fresh bleeding was defined as bleeding for over 15 minutes. (NCT05867342)
Timeframe: 1 week after the surgery (up to 2 minutes to complete assessment)

Interventionnostrils (Count of Units)
1:1000 Epinephrine Plus Saline7
1:1000 Epinephrine Plus Infiltration of 1% Lidocaine With 1:100,000 Epinephrine5

Postoperative Bloody Discharge Grading Score

Grading of postoperative bloody discharge postoperatively assessed by patient using the 1-week postoperative bleeding questionnaire. Scores range from 0 (no bleeding) to 5 (continuous heavy bleeding necessitating medical care). (NCT05867342)
Timeframe: 1 week after the surgery (up to 2 minutes to complete assessment)

Interventionscore on a scale (Mean)
1:1000 Epinephrine Plus Saline2.38
1:1000 Epinephrine Plus Infiltration of 1% Lidocaine With 1:100,000 Epinephrine2.2

Surgical Field Grading Score

The video recording of the endoscopic sinus surgery of the participant was graded by another otolaryngology specialist postoperatively and graded according to Wormald Surgical Field Grading Scale. Scores range from 0 (no bleeding) to 10 (severe bleeding with nasal cavity filling rapidly). (NCT05867342)
Timeframe: postoperatively (approximately 20 minutes to assess)

Interventionscore on a scale (Mean)
1:1000 Epinephrine Plus Saline3.54
1:1000 Epinephrine Plus Infiltration of 1% Lidocaine With 1:100,000 Epinephrine3.23

Trials

6 trials available for lidocaine and Sinusitis

ArticleYear
Effects of glove finger- versus lidocaine-soaked nasal packing after endoscopic nasal surgery: a prospective randomized controlled trial.
    European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2020, Volume: 277, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anesthetics, Local; Bandages; Endoscopy; Epistaxis; Fema

2020
The effect of topical epinephrine 1:1000 with and without infiltration of 1% lidocaine with epinephrine 1:100,000 on endoscopic surgical field visualization: a double-blind randomized controlled study.
    International forum of allergy & rhinology, 2020, Volume: 10, Issue:2

    Topics: Administration, Topical; Adult; Aged; Anesthetics, Local; Blood Loss, Surgical; Chronic Disease; Dou

2020
The Role of Endoscopic Sphenopalatine Ganglion Block on Nausea and Vomiting After Sinus Surgery.
    American journal of rhinology & allergy, 2018, Volume: 32, Issue:5

    Topics: Adult; Anesthesia, General; Chronic Disease; Double-Blind Method; Drug Combinations; Endoscopy; Epin

2018
Does pterygopalatine canal injection with local anaesthetic and adrenaline decrease bleeding during functional endoscopic sinus surgery?
    The Journal of laryngology and otology, 2014, Volume: 128, Issue:9

    Topics: Adult; Aged; Anesthetics, Local; Blood Loss, Surgical; Chronic Disease; Epinephrine; Epistaxis; Fema

2014
Different anesthetic agents-soaked sinus packings on pain management after functional endoscopic sinus surgery: which is the most effective?
    European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2016, Volume: 273, Issue:7

    Topics: Adolescent; Adult; Amides; Anesthetics, Local; Bandages; Bupivacaine; Chronic Disease; Endoscopy; Fe

2016
Different anesthetic agents-soaked sinus packings on pain management after functional endoscopic sinus surgery: which is the most effective?
    European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2016, Volume: 273, Issue:7

    Topics: Adolescent; Adult; Amides; Anesthetics, Local; Bandages; Bupivacaine; Chronic Disease; Endoscopy; Fe

2016
Different anesthetic agents-soaked sinus packings on pain management after functional endoscopic sinus surgery: which is the most effective?
    European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2016, Volume: 273, Issue:7

    Topics: Adolescent; Adult; Amides; Anesthetics, Local; Bandages; Bupivacaine; Chronic Disease; Endoscopy; Fe

2016
Different anesthetic agents-soaked sinus packings on pain management after functional endoscopic sinus surgery: which is the most effective?
    European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2016, Volume: 273, Issue:7

    Topics: Adolescent; Adult; Amides; Anesthetics, Local; Bandages; Bupivacaine; Chronic Disease; Endoscopy; Fe

2016
Epinephrine/Lidocaine injection vs. saline during endoscopic sinus surgery.
    The Laryngoscope, 2008, Volume: 118, Issue:7

    Topics: Acute Disease; Adolescent; Adult; Aged; Anesthesia, General; Anesthesia, Local; Blood Loss, Surgical

2008

Other Studies

9 other studies available for lidocaine and Sinusitis

ArticleYear
Rhinosinusitis associated with post-dental extraction chronic oroantral fistula: outcomes of non-surgical management comprising antibiotics and local decongestion therapy.
    The Journal of laryngology and otology, 2016, Volume: 130, Issue:6

    Topics: Administration, Topical; Adult; Aged; Anesthetics, Local; Anti-Bacterial Agents; Chronic Disease; Fe

2016
Preoperative β-blockade and hypertension in the first hour of functional endoscopic sinus surgery.
    The Laryngoscope, 2017, Volume: 127, Issue:7

    Topics: Administration, Topical; Adrenergic beta-Antagonists; Adult; Anesthetics, Local; Chronic Disease; Dr

2017
Reversible nasal airway obstruction: does change in nasal peak inspiratory flow following decongestion predict response to topical steroids in chronic rhinosinusitis patients?
    The Journal of laryngology and otology, 2012, Volume: 126, Issue:12

    Topics: Administration, Intranasal; Adult; Aged; Chronic Disease; Humans; Lidocaine; Middle Aged; Nasal Deco

2012
Somato-sympathetic vasoconstriction to intranasal fluid administration with consecutive decrease in nasal nitric oxide.
    Acta physiologica Scandinavica, 2003, Volume: 177, Issue:4

    Topics: Acetylcysteine; Administration, Intranasal; Adult; Anesthetics, Local; Chronic Disease; Expectorants

2003
[BRONCHIAL ASTHMA AS A RESULT OF LIDOCAINE ALLERGY].
    Allergie und Asthma, 1963, Volume: 9

    Topics: Asthma; Drug Hypersensitivity; Humans; Lidocaine; Sinusitis; Skin Tests; Surgical Procedures, Operat

1963
THE EFFECT OF TEMPORARY AUTONOMIC BLOCK ON THE SO-CALLED ALLERGIC CONDITIONS OF THE NASAL MUCOSA: "A PRELIMINARY REPORT".
    The Journal of laryngology and otology, 1965, Volume: 79

    Topics: Autonomic Nerve Block; Humans; Lidocaine; Nasal Mucosa; Nasal Polyps; Rhinitis, Allergic, Seasonal;

1965
Transient abducens nerve palsy during endoscopic sinus surgery: report of three cases.
    Auris, nasus, larynx, 2007, Volume: 34, Issue:2

    Topics: Abducens Nerve Diseases; Adolescent; Anesthesia, Local; Chronic Disease; Diplopia; Endoscopy; Humans

2007
[Ligenten treatment of sinusitis].
    Vestnik otorinolaringologii, 1997, Issue:2

    Topics: Administration, Topical; Adult; Anti-Infective Agents; Drug Combinations; Female; Gels; Gentamicins;

1997
Maxillary antral lavage--infiltration and surface anaesthesia compared.
    The Journal of laryngology and otology, 1989, Volume: 103, Issue:6

    Topics: Administration, Topical; Adolescent; Adult; Aged; Anesthesia, Local; Cocaine; Epinephrine; Female; H

1989