Page last updated: 2024-10-28

lidocaine and Shock

lidocaine has been researched along with Shock in 41 studies

Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.

Shock: A pathological condition manifested by failure to perfuse or oxygenate vital organs.

Research Excerpts

ExcerptRelevanceReference
"A 9-year-old boy who developed a life-threatening anaphylaxis reaction of the airway and subsequent dyspnea and circulation collapse because of instilled the topical lidocaine into the airway within 2 min before performing flexible bronchoscopy (FB)."7.77Life-threatening anaphylactic reaction after the administration of airway topical lidocaine. ( Jeng, MJ; Lee, YS; Peng, YY; Soong, WJ; Soong, YH; Tsao, PC; Yang, CF, 2011)
"In a rat model of intracranial balloon inflation, intrathecal lidocaine prevented cardiovascular collapse and neurogenic pulmonary edema."7.71Intrathecal lidocaine prevents cardiovascular collapse and neurogenic pulmonary edema in a rat model of acute intracranial hypertension. ( Ford, S; Hall, SR; Hong, M; Milne, B; Wang, L, 2002)
"A quantitative liver test based on the formation of the lidocaine metabolite monoethylglycinexylidide (MEGX), was used to evaluate the effect of hemorrhagic shock at 40 mmHg for 90 min on Sprague-Dawley rats."7.69MEGX (monoethylglycinexylidide): a novel in vivo test to measure early hepatic dysfunction after hypovolemic shock. ( Baue, AE; Chandel, B; Jellinek, M; Kurtz, M; Matthews, M; Rana, WU; Shapiro, MJ, 1995)
"Hypothesizing that propofol's pro and anticonvulsant effects might be dose dependent, we determined the effect of 25, 50, and 100% of a previously determined anesthetic dose of propofol for rats on the amount of lidocaine required to induce seizures."7.69Propofol prevents or elevates the threshold for lidocaine-induced seizures in rats. ( Cottrell, JE; Hartung, J; Weinberger, J; Ying, H, 1994)
" In contrast, ovine pregnancy does not enhance the toxicity of mepivacaine, a drug with properties similar to lidocaine."7.68Pregnancy does not alter lidocaine toxicity. ( Arthur, GR; Covino, BG; Finster, M; Morishima, HO, 1990)
"A 9-year-old boy who developed a life-threatening anaphylaxis reaction of the airway and subsequent dyspnea and circulation collapse because of instilled the topical lidocaine into the airway within 2 min before performing flexible bronchoscopy (FB)."3.77Life-threatening anaphylactic reaction after the administration of airway topical lidocaine. ( Jeng, MJ; Lee, YS; Peng, YY; Soong, WJ; Soong, YH; Tsao, PC; Yang, CF, 2011)
"In a rat model of intracranial balloon inflation, intrathecal lidocaine prevented cardiovascular collapse and neurogenic pulmonary edema."3.71Intrathecal lidocaine prevents cardiovascular collapse and neurogenic pulmonary edema in a rat model of acute intracranial hypertension. ( Ford, S; Hall, SR; Hong, M; Milne, B; Wang, L, 2002)
"A quantitative liver test based on the formation of the lidocaine metabolite monoethylglycinexylidide (MEGX), was used to evaluate the effect of hemorrhagic shock at 40 mmHg for 90 min on Sprague-Dawley rats."3.69MEGX (monoethylglycinexylidide): a novel in vivo test to measure early hepatic dysfunction after hypovolemic shock. ( Baue, AE; Chandel, B; Jellinek, M; Kurtz, M; Matthews, M; Rana, WU; Shapiro, MJ, 1995)
"Hypothesizing that propofol's pro and anticonvulsant effects might be dose dependent, we determined the effect of 25, 50, and 100% of a previously determined anesthetic dose of propofol for rats on the amount of lidocaine required to induce seizures."3.69Propofol prevents or elevates the threshold for lidocaine-induced seizures in rats. ( Cottrell, JE; Hartung, J; Weinberger, J; Ying, H, 1994)
" In contrast, ovine pregnancy does not enhance the toxicity of mepivacaine, a drug with properties similar to lidocaine."3.68Pregnancy does not alter lidocaine toxicity. ( Arthur, GR; Covino, BG; Finster, M; Morishima, HO, 1990)
" An identical sequence of toxic manifestations occurred in the adult, newborn, and fetus: convulsions, hypotension, respiratory arrest, and circulatory collapse."1.26Toxicity of lidocaine in adult, newborn, and fetal sheep. ( Bruce, SL; Covino, BG; Finster, M; Gutsche, BB; Morishima, HO; Pedersen, H; Sakuma, K; Stark, RI, 1981)

Research

Studies (41)

TimeframeStudies, this research(%)All Research%
pre-199030 (73.17)18.7374
1990's5 (12.20)18.2507
2000's2 (4.88)29.6817
2010's4 (9.76)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Xiang, L1
Klemcke, HG1
Ryan, KL1
Osman, BM1
Maga, JM1
Baquero, SM1
Soong, WJ1
Lee, YS1
Soong, YH1
Tsao, PC1
Yang, CF1
Jeng, MJ1
Peng, YY1
Sambrook, PJ1
Smith, W1
Elijah, J1
Goss, AN1
Koerner, KR1
Taylor, SE1
HIGASHINO, KI1
DAWSON-BUTTERWORTH, K1
NAGOSHI, Y1
KANEKO, Z1
UMEZAWA, S1
MICHINOSHITA, K1
YAMAMOTO, K1
NAKAI, Y1
FUKUDA, S1
AOKI, S1
MIYABE, I1
SUGIYAMA, S1
HONJO, S1
YAMADA, T1
KIMURA, S1
NAKAZAWA, A1
FURUYA, M1
HOSOGAWA, A1
KOBAYASHI, Y1
GORDH, T1
NAHOR, A1
MILLIKEN, J1
MINTON, R2
FINE, J2
Grimm, H1
Ward, JT1
Marx, GF1
Morishima, HO3
Pedersen, H2
Finster, M3
Sakuma, K1
Bruce, SL1
Gutsche, BB1
Stark, RI1
Covino, BG3
Brown, DL1
Ransom, DM1
Hall, JA1
Leicht, CH1
Schroeder, DR1
Offord, KP1
Ngan-Kee, WD1
Lee, BB1
Chandel, B1
Shapiro, MJ1
Kurtz, M1
Rana, WU1
Matthews, M1
Jellinek, M1
Baue, AE1
Hartung, J1
Ying, H1
Weinberger, J1
Cottrell, JE1
Hall, SR1
Wang, L1
Milne, B1
Ford, S1
Hong, M1
Arthur, GR2
Duranteau, J1
Edouard, A1
Tarot, J1
Pussard, E1
Berdeaux, A1
Rice, LJ1
Broadman, LM1
Matsumiya, N1
Dohi, S1
Takahashi, H1
Kondo, Y1
Naito, H1
Nakhosteen, JA1
Dohrn, GA1
Wassermann, K1
Oevrenes, A1
Hiraoka, H1
Tsuji, A1
Feldman, HS1
Lawrie, DM1
Higgins, MR1
Godman, MJ1
Oliver, MF1
Julian, DG1
Donald, KW1
Grossman, JI1
Rubin, IL1
Morikawa, KI1
Bonica, JJ1
Tucker, GT1
Murphy, TM1
Sloman, G1
Aas, E1
Lindquist, B1
Browne, RA1
Ashworth, EJ1
Rossi, P1
Floris, B1
Piccardo, G1
Giovannini, E1
De Rubertis, C1
Mattei, G1
Pacilli, L1
Dieterle, P1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Immune Response of Breast Cancer Patients Treated With Levobupivacaine Using Paravertebral or Superficial Chest Blocks[NCT05816538]100 participants (Anticipated)Interventional2023-04-30Not yet recruiting
Comparison of Atropine Versus Glycopyrrolate in Preventing Spinal Anesthesia Induced Hypotension in Adult Patient Undergoing Major Lower Limb Orthopedic Surgeries[NCT03580889]Phase 4138 participants (Anticipated)Interventional2017-09-15Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for lidocaine and Shock

ArticleYear
Changing concepts in the care of patients with acute myocardial infarction.
    The Medical journal of Australia, 1969, Jun-07, Volume: 1, Issue:23

    Topics: Arrhythmias, Cardiac; Atrial Fibrillation; Blood Gas Analysis; Bundle-Branch Block; Cardiac Output;

1969

Other Studies

40 other studies available for lidocaine and Shock

ArticleYear
The life-saving effect of "adenosine, lidocaine, and magnesium" cocktail during hypovolemic shock: One stone, three birds?
    The journal of trauma and acute care surgery, 2018, Volume: 84, Issue:1

    Topics: Adenosine; Animals; Birds; Hypovolemia; Lidocaine; Magnesium; Rats; Shock

2018
Case report: management of differential diagnosis and treatment of severe anaphylaxis in the setting of spinal anesthesia.
    Journal of clinical anesthesia, 2016, Volume: 35

    Topics: Anaphylaxis; Anesthesia, Spinal; Anesthetics, Intravenous; Anesthetics, Local; Arthroplasty, Replace

2016
Life-threatening anaphylactic reaction after the administration of airway topical lidocaine.
    Pediatric pulmonology, 2011, Volume: 46, Issue:5

    Topics: Administration, Topical; Anaphylaxis; Anesthetics, Local; Bronchoscopy; Child; Dyspnea; Humans; Lido

2011
Severe adverse reactions to dental local anaesthetics: systemic reactions.
    Australian dental journal, 2011, Volume: 56, Issue:2

    Topics: Adolescent; Adult; Adverse Drug Reaction Reporting Systems; Aged; Aged, 80 and over; Anesthesia, Den

2011
Emergencies associated with local anesthetics.
    Dentistry today, 2000, Volume: 19, Issue:10

    Topics: Adolescent; Adult; Akathisia, Drug-Induced; Anesthesia, Dental; Anesthetics, Local; Brain; Child, Pr

2000
An invalidated state followed the shock due to xylocaine-anesthesia.
    The science reports of the research institutes, Tohoku University. Ser. C, Medicine. Tohoku Daigaku, 1959, Volume: 9

    Topics: Analgesia; Anesthesia; Anesthesia and Analgesia; Brain; Brain Diseases; Lidocaine; Pain; Pain Manage

1959
Dangers of lignocaine.
    British medical journal, 1963, Jun-22, Volume: 1, Issue:5346

    Topics: Humans; Lidocaine; Shock

1963
[CASES OF SHOCK-LIKE CONDITIONS. (3) CLINICAL CASES OF SHOCK-LIKE CONDITIONS CAUSED BY DRUGS].
    Jibi inkoka Otolaryngology, 1963, Volume: 35

    Topics: Adolescent; Child; Drug Hypersensitivity; Lidocaine; Otolaryngology; Penicillins; Procaine; Shock; S

1963
[CASES OF SHOCK-LIKE CONDITIONS. (6)].
    Jibi inkoka Otolaryngology, 1963, Volume: 35

    Topics: Adenoidectomy; Child; Cocaine; Drug Hypersensitivity; Lidocaine; Otolaryngology; Shock; Shock, Septi

1963
[CASES OF SHOCK-LIKE CONDITIONS. (8)].
    Jibi inkoka Otolaryngology, 1963, Volume: 35

    Topics: Drug Hypersensitivity; Heart Massage; Infant; Lidocaine; Otolaryngology; Resuscitation; Shock; Shock

1963
[CASE OF SUCCESSFUL TREATMENT OF SHOCK IN TONSILLECTOMY AND MEASURES FOR PREVENTING IT].
    Jibi inkoka Otolaryngology, 1963, Volume: 35

    Topics: Blood Sedimentation; Blood Transfusion; Caffeine; Cyanosis; Drug Hypersensitivity; Electrocardiograp

1963
[CASE OF SHOCK CAUSED BY LOCAL ANESTHESIA].
    Jibi inkoka Otolaryngology, 1963, Volume: 35

    Topics: Anesthesia, Local; Blood Transfusion; Cocaine; Drug Hypersensitivity; Lidocaine; Oxygen Inhalation T

1963
[5 RECENT CASES OF LOCAL ANESTHETIC TOXICITY IN TONSILLECTOMY].
    Jibi inkoka Otolaryngology, 1963, Volume: 35

    Topics: Anesthesia, Local; Anesthetics, Local; Child; Cocaine; Drug Hypersensitivity; Lidocaine; Pharmacolog

1963
HEART-VOLUME STUDIES III. PHONOCARDIOGRAPHIC AND ELECTROCARDIOGRAPHIC CHANGES DURING DILATATION OF THE HEART IN THE RABBIT.
    Acta anaesthesiologica Scandinavica, 1964, Volume: 8

    Topics: Aged; Dilatation; Electrocardiography; Heart; Humans; Hypoxia; Lidocaine; Phonocardiography; Shock;

1964
TECHNIQUE OF CELIAC BLOCKADE FOR RELIEF OF SPLANCHNIC ISCHEMIA.
    JAMA, 1965, May-17, Volume: 192

    Topics: Animals; Autonomic Nerve Block; Celiac Plexus; Dogs; Ethanol; Ischemia; Lidocaine; Rabbits; Shock; S

1965
[Emergency equipment, emergency drugs, emergency measures from the anesthesist's viewpoint].
    Fortschritte der Medizin, 1983, Jun-23, Volume: 101, Issue:24

    Topics: Analgesics; Anesthesiology; Bicarbonates; Calcium; Electric Countershock; Emergencies; Epinephrine;

1983
Endotracheal drug therapy.
    The American journal of emergency medicine, 1983, Volume: 1, Issue:1

    Topics: Absorption; Atropine; Diazepam; Drug Therapy; Emergencies; Epinephrine; History, 18th Century; Histo

1983
Cardiotoxicity of local anesthetics--the plot thickens.
    Anesthesiology, 1984, Volume: 60, Issue:1

    Topics: Anesthesia, Obstetrical; Anesthetics, Local; Animals; Bupivacaine; Etidocaine; Female; Heart Arrest;

1984
Toxicity of lidocaine in adult, newborn, and fetal sheep.
    Anesthesiology, 1981, Volume: 55, Issue:1

    Topics: Animals; Animals, Newborn; Cardiovascular System; Central Nervous System; Female; Fetus; Hypotension

1981
Regional anesthesia and local anesthetic-induced systemic toxicity: seizure frequency and accompanying cardiovascular changes.
    Anesthesia and analgesia, 1995, Volume: 81, Issue:2

    Topics: Adult; Anesthesia, Caudal; Anesthesia, Epidural; Anesthetics; Anesthetics, Local; Blood Pressure; Br

1995
Cardiovascular collapse after combined spinal anaesthesia and interscalene brachial plexus block.
    Anaesthesia and intensive care, 1995, Volume: 23, Issue:2

    Topics: Aged; Anesthesia, Spinal; Brachial Plexus; Bupivacaine; Femoral Neck Fractures; Fracture Fixation, I

1995
MEGX (monoethylglycinexylidide): a novel in vivo test to measure early hepatic dysfunction after hypovolemic shock.
    Shock (Augusta, Ga.), 1995, Volume: 3, Issue:1

    Topics: Animals; Biotransformation; Ischemia; Lidocaine; Liver; Liver Function Tests; Male; Microsomes, Live

1995
Propofol prevents or elevates the threshold for lidocaine-induced seizures in rats.
    Journal of neurosurgical anesthesiology, 1994, Volume: 6, Issue:4

    Topics: Animals; Anticonvulsants; Blood Pressure; Dose-Response Relationship, Drug; Electroencephalography;

1994
Intrathecal lidocaine prevents cardiovascular collapse and neurogenic pulmonary edema in a rat model of acute intracranial hypertension.
    Anesthesia and analgesia, 2002, Volume: 94, Issue:4

    Topics: Acute Disease; Anesthetics, Local; Animals; Blood Pressure; Brain; Electrocardiography; Heart Rate;

2002
Pregnancy does not alter lidocaine toxicity.
    American journal of obstetrics and gynecology, 1990, Volume: 162, Issue:5

    Topics: Animals; Blood Pressure; Bupivacaine; Female; Heart Rate; Hypotension; Lidocaine; Mepivacaine; Pregn

1990
[Modification of reflex responses to hypovolemia by lidocaine in man].
    Annales francaises d'anesthesie et de reanimation, 1989, Volume: 8 Suppl

    Topics: Adult; Humans; Lidocaine; Reflex; Shock

1989
Caudal anesthesia and cardiovascular collapse in an infant.
    Anesthesia and analgesia, 1987, Volume: 66, Issue:7

    Topics: Anesthesia, Caudal; Anesthesia, Epidural; Epinephrine; Humans; Infant; Lidocaine; Shock

1987
Cardiovascular collapse in an infant after caudal anesthesia with a lidocaine-epinephrine solution.
    Anesthesia and analgesia, 1986, Volume: 65, Issue:10

    Topics: Anesthesia, Caudal; Anesthesia, Epidural; Cardiovascular System; Epinephrine; Humans; Infant; Lidoca

1986
[Severe complications following topical inhalation anesthesia with 10% lidocaine for bronchoscopies with local anesthesia].
    Praxis und Klinik der Pneumologie, 1985, Volume: 39, Issue:9

    Topics: Adult; Anesthesia, Inhalation; Anesthesia, Local; Bronchial Spasm; Bronchoscopy; Heart Arrest; Human

1985
Bupivacaine toxicity in pregnant and nonpregnant ewes.
    Anesthesiology, 1985, Volume: 63, Issue:2

    Topics: Animals; Blood Pressure; Bupivacaine; Dose-Response Relationship, Drug; Etidocaine; Female; Fetus; H

1985
Ventricular fibrillation complicating acute myocardial infarction.
    Lancet (London, England), 1968, Sep-07, Volume: 2, Issue:7567

    Topics: Age Factors; Arrhythmias, Cardiac; Female; Follow-Up Studies; Heart Arrest; Humans; Lidocaine; Male;

1968
Cardiopulmonary resuscitation. II.
    American heart journal, 1969, Volume: 78, Issue:5

    Topics: Acidosis; Aftercare; Bradycardia; Heart Arrest; Humans; Hyperkalemia; Hypokalemia; Isoproterenol; Li

1969
Effect of acute hypovolaemia on lignocaine absorption and cardiovascular response following epidural block in dogs.
    British journal of anaesthesia, 1974, Volume: 46, Issue:9

    Topics: Analgesia, Epidural; Animals; Depression, Chemical; Dogs; Hemodynamics; Lidocaine; Shock

1974
[On states of collapse and their treatment in practice].
    Den Norske tannlaegeforenings tidende, 1965, Volume: 75, Issue:9

    Topics: Anesthesia, Dental; Humans; Lidocaine; Practice Management, Dental; Shock

1965
Propulsive gastrointestinal motility related to retroperitoneal irritation. An experimental study in the rat.
    Acta chirurgica Scandinavica. Supplementum, 1968, Volume: 384

    Topics: Anesthesia, Local; Animals; Autonomic Nerve Block; Blood; Chromium Isotopes; Digestive System; Gastr

1968
The use of epidural block in acute pancreatitis: a report of eight cases.
    Canadian Anaesthetists' Society journal, 1969, Volume: 16, Issue:5

    Topics: Acute Disease; Adult; Aged; Anesthesia, Spinal; Electrocardiography; Electrolytes; Female; Humans; L

1969
[Pharmacological therapy and temporary intracardiac electrostimulation in treatment of atrioventricular block in acute myocardial infarct].
    Atti della Societa italiana di cardiologia, 1969, Jan-21, Volume: 2

    Topics: Adrenal Cortex Hormones; Arrhythmias, Cardiac; Atropine; Heart Block; Heart Failure; Humans; Lidocai

1969
[On a case of reflex anuria. Considerations of a therapeutic nature].
    Minerva ginecologica, 1967, Jul-15, Volume: 19, Issue:13

    Topics: Anuria; Female; Humans; Lidocaine; Middle Aged; Peritonitis; Reflex; Shock

1967
Mechanism of action of bacterial endotoxin.
    Nature, 1966, Apr-02, Volume: 210, Issue:5031

    Topics: Animals; Catecholamines; Celiac Plexus; Endotoxins; Lidocaine; Liver; Mononuclear Phagocyte System;

1966
[State of severe shock after local anesthesia and its emergency treatment].
    Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde, 1966, Volume: 152, Issue:4

    Topics: Anesthesia, Local; Humans; Lidocaine; Resuscitation; Shock

1966