Page last updated: 2024-10-28

lidocaine and Sclerosis, Systemic

lidocaine has been researched along with Sclerosis, Systemic in 6 studies

Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.

Research Excerpts

ExcerptRelevanceReference
" No systemic adverse event due to topical lidocaine were observed."5.46Lidocaine controls pain and allows safe wound bed preparation and debridement of digital ulcers in systemic sclerosis: a retrospective study. ( Bartoli, F; Braschi, F; Bruni, C; De Paulis, A; Fantauzzo, C; Fiori, G; Matucci-Cerinic, M; Paganelli, L; Rasero, L, 2017)
"Lidocaine seems to be an alternative treatment for scleroderma considering that: a) the patient's having excessive collagen deposits in tissues affected by scleroderma; b) the patient's demonstrating increased activity of the enzyme prolyl hydroxylase, an essential enzyme for the biosynthesis of collagen; and c) lidocaine's reducing the activity of prolyl hydroxylase."2.76Lidocaine for systemic sclerosis: a double-blind randomized clinical trial. ( Andrade, LE; Kayser, C; Riera, R; Souza, AW; Trevisani, VF; Yanagita, ET, 2011)
" No systemic adverse event due to topical lidocaine were observed."1.46Lidocaine controls pain and allows safe wound bed preparation and debridement of digital ulcers in systemic sclerosis: a retrospective study. ( Bartoli, F; Braschi, F; Bruni, C; De Paulis, A; Fantauzzo, C; Fiori, G; Matucci-Cerinic, M; Paganelli, L; Rasero, L, 2017)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19902 (33.33)18.7374
1990's0 (0.00)18.2507
2000's2 (33.33)29.6817
2010's2 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Braschi, F1
Bartoli, F1
Bruni, C1
Fiori, G1
Fantauzzo, C1
Paganelli, L1
De Paulis, A1
Rasero, L1
Matucci-Cerinic, M1
Riera, R1
Andrade, LE1
Souza, AW1
Kayser, C1
Yanagita, ET1
Trevisani, VF1
Ozgocmen, S1
Kaya, A1
Coskun, BK1
Roustit, M1
Simmons, GH1
Carpentier, P1
Cracowski, JL1
Lewis, GB1
Eisele, JH1
Reitan, JA1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Double-blind Randomized Clinical Trial to Evaluate the Reduction of Pain in the Wounds Treatment Previously Applying Lidocaine Topical Solution vs Placebo, in the Outpatients Area.[NCT03676556]Phase 346 participants (Anticipated)Interventional2021-06-16Recruiting
Randomised, Double-blind Clinical Trial to Evaluate the Reduction of Pain in the Wounds Treatment Previously Applying Lidocaine Topical Solution vs Placebo[NCT02584335]Phase 47 participants (Actual)Interventional2015-07-31Terminated (stopped due to Difficulties with the recruitment)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for lidocaine and Sclerosis, Systemic

ArticleYear
Lidocaine for systemic sclerosis: a double-blind randomized clinical trial.
    Orphanet journal of rare diseases, 2011, Feb-07, Volume: 6

    Topics: Adult; Double-Blind Method; Female; Humans; Lidocaine; Male; Middle Aged; Scleroderma, Systemic; Tre

2011

Other Studies

5 other studies available for lidocaine and Sclerosis, Systemic

ArticleYear
Lidocaine controls pain and allows safe wound bed preparation and debridement of digital ulcers in systemic sclerosis: a retrospective study.
    Clinical rheumatology, 2017, Volume: 36, Issue:1

    Topics: Aged; Anesthetics, Local; Debridement; Female; Fingers; Humans; Lidocaine; Male; Middle Aged; Pain;

2017
Topical lidocaine helps reduce pain of digital ulcers in systemic sclerosis (scleroderma).
    Clinical rheumatology, 2006, Volume: 25, Issue:3

    Topics: Administration, Oral; Administration, Topical; Anesthetics, Local; Anti-Infective Agents; Ciprofloxa

2006
Topical lidocaine helps reduce pain of digital ulcers in systemic sclerosis (scleroderma).
    Clinical rheumatology, 2006, Volume: 25, Issue:3

    Topics: Administration, Oral; Administration, Topical; Anesthetics, Local; Anti-Infective Agents; Ciprofloxa

2006
Topical lidocaine helps reduce pain of digital ulcers in systemic sclerosis (scleroderma).
    Clinical rheumatology, 2006, Volume: 25, Issue:3

    Topics: Administration, Oral; Administration, Topical; Anesthetics, Local; Anti-Infective Agents; Ciprofloxa

2006
Topical lidocaine helps reduce pain of digital ulcers in systemic sclerosis (scleroderma).
    Clinical rheumatology, 2006, Volume: 25, Issue:3

    Topics: Administration, Oral; Administration, Topical; Anesthetics, Local; Anti-Infective Agents; Ciprofloxa

2006
Abnormal digital neurovascular response to local heating in systemic sclerosis.
    Rheumatology (Oxford, England), 2008, Volume: 47, Issue:6

    Topics: Adolescent; Adult; Aged; Anesthetics, Local; Axons; Female; Fingers; Forearm; Hot Temperature; Human

2008
Prolonged regional analgesia in scleroderma.
    Canadian Anaesthetists' Society journal, 1974, Volume: 21, Issue:5

    Topics: Amputation, Surgical; Analgesia; Bicarbonates; Dextrans; Female; Fingers; Humans; Hydrogen-Ion Conce

1974
Scleroderma, Raynaud's phenomenon, and local anesthetics.
    Anesthesiology, 1971, Volume: 34, Issue:4

    Topics: Aged; Anesthesia, Local; Humans; Lidocaine; Male; Raynaud Disease; Scleroderma, Systemic

1971