lidocaine has been researched along with Sciatica in 30 studies
Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.
Sciatica: A condition characterized by pain radiating from the back into the buttock and posterior/lateral aspects of the leg. Sciatica may be a manifestation of SCIATIC NEUROPATHY; RADICULOPATHY (involving the SPINAL NERVE ROOTS; L4, L5, S1, or S2, often associated with INTERVERTEBRAL DISK DISPLACEMENT); or lesions of the CAUDA EQUINA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A 75% to 100% reduction of the low back pain was experienced by 13 patients, and a 75% to 100% reduction of the radiating pain was experienced by 16 patients within 60 seconds after the intradiskal injection of lidocaine." | 3.69 | Radiating pain to the lower extremities caused by lumbar disk rupture without spinal nerve root involvement. ( Breton, G; Fontaine, S; Lepanto, L; Milette, PC, 1995) |
| "A 51-year-old male with a huge chondrosarcoma received subarachnoid dorsal root blocks with 10% phenol in glycerine to treat severe pain along the left leg." | 3.68 | A low frequency, high amplitude rhythmic fluctuation of laser-Doppler skin blood flow after subarachnoid phenol block. ( Gotou, K; Kano, T; Morioka, T; Shimoda, O, 1993) |
| "To analyze the effect of lidocaine on postoperative pain relief, we performed compression of the right sciatic nerve in Wistar rats and observed the differences on behavior between the group that received lidocaine and the group that was not treated with the local anesthetics pre-operatively." | 1.35 | Preemptive analgesic effect of lidocaine in a chronic neuropathic pain model. ( Almeida, JP; Batista, IM; Batista, LM; Carvalho, CH; Castro-Costa, CM; Castro-Costa, SB, 2009) |
| "The cause of sciatica has been studied by blocking spinal nerves of the lumbosacral plexus in intervertebral foramina." | 1.26 | Spinal nerve block. A diagnostic test in sciatica. ( Jussila, P; Wilppula, E, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (50.00) | 18.7374 |
| 1990's | 5 (16.67) | 18.2507 |
| 2000's | 9 (30.00) | 29.6817 |
| 2010's | 1 (3.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Song, Z | 1 |
| Ansah, OB | 1 |
| Meyerson, BA | 1 |
| Pertovaara, A | 1 |
| Linderoth, B | 1 |
| Laiq, N | 1 |
| Khan, MN | 1 |
| Iqbal, MJ | 1 |
| Khan, S | 1 |
| Batista, LM | 1 |
| Batista, IM | 1 |
| Almeida, JP | 1 |
| Carvalho, CH | 1 |
| Castro-Costa, SB | 1 |
| Castro-Costa, CM | 1 |
| Persaud, N | 1 |
| Strichartz, GR | 1 |
| Dashfield, AK | 1 |
| Taylor, MB | 1 |
| Cleaver, JS | 1 |
| Farrow, D | 1 |
| Sangwan, SS | 1 |
| Mittal, R | 1 |
| Kundu, ZS | 1 |
| Siwach, RC | 1 |
| Aggarwal, S | 1 |
| Garg, RK | 1 |
| Thakkar, CJ | 1 |
| Maniar, AU | 1 |
| Laheri, V | 1 |
| Gandhi, M | 1 |
| Talwalkar, C | 1 |
| Arct, W | 1 |
| Carrera, GF | 2 |
| Milette, PC | 1 |
| Fontaine, S | 1 |
| Lepanto, L | 1 |
| Breton, G | 1 |
| Stanley, D | 1 |
| Stockley, I | 1 |
| Davies, GK | 1 |
| Getty, CJ | 1 |
| Kano, T | 1 |
| Shimoda, O | 1 |
| Gotou, K | 1 |
| Morioka, T | 1 |
| Tajiri, K | 1 |
| Takahashi, K | 1 |
| Ikeda, K | 1 |
| Tomita, K | 1 |
| Rosina, P | 1 |
| Chieregato, C | 1 |
| Miccolis, D | 1 |
| D'Onghia, FS | 1 |
| Vad, VB | 1 |
| Bhat, AL | 1 |
| Lutz, GE | 1 |
| Cammisa, F | 1 |
| Fishman, LM | 1 |
| Dombi, GW | 1 |
| Michaelsen, C | 1 |
| Ringel, S | 1 |
| Rozbruch, J | 1 |
| Rosner, B | 1 |
| Weber, C | 1 |
| Smith, LJ | 1 |
| Shih, A | 1 |
| Miletic, G | 1 |
| Miletic, V | 1 |
| Krempen, JF | 2 |
| Smith, BS | 3 |
| DeFreest, LJ | 1 |
| Yates, DW | 1 |
| Wilppula, E | 1 |
| Jussila, P | 1 |
| Gentili, ME | 1 |
| Samii, K | 1 |
| Biliński, P | 1 |
| Wall, A | 1 |
| Xavier, AV | 1 |
| McDanal, J | 1 |
| Kissin, I | 1 |
| Haueisen, DC | 1 |
| Myers, SR | 1 |
| Pryce, ML | 1 |
| Durand, H | 1 |
| Masson, V | 1 |
| Matte, R | 1 |
| Plante, JM | 1 |
| Haimovici, H | 1 |
| Burn, JM | 1 |
| Langdon, L | 1 |
| Bhatia, MT | 1 |
| Parikh, CJ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Diode Laser as a Biomarker for Neuropathic Pain of Peripheral Origin.[NCT06030297] | 301 participants (Anticipated) | Interventional | 2022-11-01 | Recruiting | |||
| Comparison of the Efficacy Between Transforaminal Steroid Epidural Injection and Epidural Neuroplasty for the Treatment of Herniated Lumbar Disc：A Single Center, Controlled Clinical Trial[NCT03101033] | 92 participants (Actual) | Interventional | 2015-05-31 | Completed | |||
| Investigation of the Presence of Piriformis Syndrome Accompanying Lumbar Radiculopathy[NCT05392933] | 40 participants (Anticipated) | Interventional | 2023-01-15 | Not yet recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
ODI (Oswestry disability index) consists of 10 subscales, which evaluates pain intensity, and functional satus of personal care, lifting, walking, sitting, standing, sleeping, sex, social life, traveling. Each subscales range from 0 to 5, with the higher score indicating more severe functional damage. the ODI score ranges from 0 to 100. it equals the sum of all the subscales and divided by 50. If the patients answers 9 subscale questions, then the total sum should be divided by 45, and by this analogy. (NCT03101033)
Timeframe: at one-month post-treatment
| Intervention | units on a scale (Mean) |
|---|---|
| Epidural Neuroplasty Group | 29.11 |
| Transforaminal Steroid Injection Group | 35.02 |
ODI (Oswestry disability index) consists of 10 subscales, which evaluates pain intensity, and functional satus of personal care, lifting, walking, sitting, standing, sleeping, sex, social life, traveling. Each subscales range from 0 to 5, with the higher score indicating more severe functional damage. the ODI score ranges from 0 to 100. it equals the sum of all the subscales and divided by 50. If the patients answers 9 subscale questions, then the total sum should be divided by 45, and by this analogy. (NCT03101033)
Timeframe: at six-month post-treatment
| Intervention | units on a scale (Mean) |
|---|---|
| Epidural Neuroplasty Group | 30.52 |
| Transforaminal Steroid Injection Group | 46.39 |
ODI (Oswestry disability index) consists of 10 subscales, which evaluates pain intensity, and functional satus of personal care, lifting, walking, sitting, standing, sleeping, sex, social life, traveling. Each subscales range from 0 to 5, with the higher score indicating more severe functional damage. the ODI score ranges from 0 to 100. it equals the sum of all the subscales and divided by 50. If the patients answers 9 subscale questions, then the total sum should be divided by 45, and by this analogy. (NCT03101033)
Timeframe: at three-month post-treatment
| Intervention | units on a scale (Mean) |
|---|---|
| Epidural Neuroplasty Group | 28.93 |
| Transforaminal Steroid Injection Group | 39.82 |
ODI (Oswestry disability index) consists of 10 subscales, which evaluates pain intensity, and functional satus of personal care, lifting, walking, sitting, standing, sleeping, sex, social life, traveling. Each subscales range from 0 to 5, with the higher score indicating more severe functional damage. the ODI score ranges from 0 to 100. it equals the sum of all the subscales and divided by 50. If the patients answers 9 subscale questions, then the total sum should be divided by 45, and by this analogy. (NCT03101033)
Timeframe: before treatment
| Intervention | units on a scale (Mean) |
|---|---|
| Epidural Neuroplasty Group | 53.85 |
| Transforaminal Steroid Injection Group | 57.84 |
VAS (Visual analogue scale), with the highest score of 10, representing the most severe pain one could experience, and the lowest score of 0, representing no pain at all. The higher score means more severe pain. (NCT03101033)
Timeframe: at one-month post-treatment
| Intervention | units on a scale (Mean) |
|---|---|
| Epidural Neuroplasty Group | 2.37 |
| Transforaminal Steroid Injection Group | 2.35 |
VAS (Visual analogue scale), with the highest score of 10, representing the most severe pain one could experience, and the lowest score of 0, representing no pain at all. The higher score means more severe pain. (NCT03101033)
Timeframe: at six-month post-treatment
| Intervention | units on a scale (Mean) |
|---|---|
| Epidural Neuroplasty Group | 2.81 |
| Transforaminal Steroid Injection Group | 4.06 |
VAS (Visual analogue scale), with the highest score of 10, representing the most severe pain one could experience, and the lowest score of 0, representing no pain at all. The higher score means more severe pain. (NCT03101033)
Timeframe: at three-month post-treatment
| Intervention | units on a scale (Mean) |
|---|---|
| Epidural Neuroplasty Group | 2.19 |
| Transforaminal Steroid Injection Group | 3.25 |
VAS (Visual analogue scale), with the highest score of 10, representing the most severe pain one could experience, and the lowest score of 0, representing no pain at all. The higher score means more severe pain. (NCT03101033)
Timeframe: before treatment
| Intervention | units on a scale (Mean) |
|---|---|
| Epidural Neuroplasty Group | 5.63 |
| Transforaminal Steroid Injection Group | 5.92 |
2 reviews available for lidocaine and Sciatica
| Article | Year |
|---|---|
Piriformis syndrome: diagnosis, treatment, and outcome--a 10-year study.
Topics: Activities of Daily Living; Anesthetics, Local; Electric Stimulation; Electrodiagnosis; Female; H-Re | 2002 |
[Accidental epidural injection of hypertonic sodium chloride solution].
Topics: Humans; Injections, Epidural; Lidocaine; Male; Malpractice; Middle Aged; Paresthesia; Saline Solutio | 1991 |
5 trials available for lidocaine and Sciatica
| Article | Year |
|---|---|
Comparison of Epidural Steroid Injections with conservative management in patients with lumbar radiculopathy.
Topics: Adult; Anesthetics, Local; Anti-Inflammatory Agents; Female; Humans; Injections, Epidural; Lidocaine | 2009 |
Comparison of caudal steroid epidural with targeted steroid placement during spinal endoscopy for chronic sciatica: a prospective, randomized, double-blind trial.
Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Local; Anti-Inflammatory Agents; Chronic Disease; Doubl | 2005 |
A prospective study of diagnostic epidural blockade in the assessment of chronic back and leg pain.
Topics: Adult; Aged; Anesthesia, Epidural; Back Pain; Diagnosis, Differential; Female; Humans; Leg; Lidocain | 1993 |
Common peroneal nerve block for sciatica.
Topics: Adult; Aged; Anesthetics, Local; Autonomic Nerve Block; Humans; Intervertebral Disc Displacement; Li | 1998 |
Transforaminal epidural steroid injections in lumbosacral radiculopathy: a prospective randomized study.
Topics: Adult; Anesthetics, Local; Betamethasone; Contrast Media; Fluoroscopy; Follow-Up Studies; Hospitals, | 2002 |
23 other studies available for lidocaine and Sciatica
| Article | Year |
|---|---|
Exploration of supraspinal mechanisms in effects of spinal cord stimulation: role of the locus coeruleus.
Topics: Action Potentials; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Antagonists; | 2013 |
Preemptive analgesic effect of lidocaine in a chronic neuropathic pain model.
Topics: Anesthetics, Local; Animals; Chronic Disease; Disease Models, Animal; Lidocaine; Pain, Postoperative | 2009 |
Micromolar lidocaine selectively blocks propagating ectopic impulses at a distance from their site of origin.
Topics: 4-Aminopyridine; Action Potentials; Anesthetics, Local; Animals; Cnidarian Venoms; Electric Stimulat | 2002 |
Prolapsed intervertebral disc with sciatica: the role of common peroneal nerve block.
Topics: Adolescent; Adult; Anesthetics, Local; Female; Humans; Intervertebral Disc Displacement; Lidocaine; | 2005 |
Caudal epidural injections in treatment of lumbo-sciatic syndrome.
Topics: Adrenal Cortex Hormones; Adult; Aged; Back Pain; Epidural Space; Female; Humans; Injections; Lidocai | 1983 |
[Use of depolarization block in the treatment of backache].
Topics: Adult; Anesthetics, Local; Back Pain; Female; Humans; Injections, Intra-Articular; Intervertebral Di | 1980 |
Lumbar facet joint injection in low back pain and sciatica: preliminary results.
Topics: Adult; Aged; Anesthetics, Local; Back Pain; Female; Fluoroscopy; Humans; Injections, Intra-Articular | 1980 |
Lumbar facet joint injection in low back pain and sciatica: description of technique.
Topics: Anesthetics, Local; Back Pain; Fluoroscopy; Humans; Injections, Intra-Articular; Joint Diseases; Lid | 1980 |
Radiating pain to the lower extremities caused by lumbar disk rupture without spinal nerve root involvement.
Topics: Adult; Anesthesia, Local; Female; Humans; Injections, Spinal; Intervertebral Disc Displacement; Lido | 1995 |
A low frequency, high amplitude rhythmic fluctuation of laser-Doppler skin blood flow after subarachnoid phenol block.
Topics: Administration, Oral; Adrenergic Fibers; Analgesia, Epidural; Autonomic Nerve Block; Capillaries; Ch | 1993 |
Psoriasis and side-effects of mesotherapy.
Topics: Aged; Aminophylline; Anesthetics, Local; Cyclosporine; Dermatologic Agents; Drug Therapy, Combinatio | 2001 |
Continual systemic infusion of lidocaine provides analgesia in an animal model of neuropathic pain.
Topics: Anesthetics, Local; Animals; Chronic Disease; Disease Models, Animal; Dose-Response Relationship, Dr | 2002 |
Selective nerve root infiltration for the evaluation of sciatica.
Topics: Back Pain; Humans; Injections; Lidocaine; Methods; Needles; Sciatica; Spinal Nerve Roots | 1975 |
A comparison of the types of epidural injection commonly used in the treatment of low back pain and sciatica.
Topics: Back Pain; Dura Mater; Humans; Injections; Lidocaine; Sciatica; Sodium Chloride; Triamcinolone Aceto | 1978 |
Spinal nerve block. A diagnostic test in sciatica.
Topics: Adult; Female; Humans; Lidocaine; Male; Myelography; Nerve Block; Sciatica; Spinal Nerves | 1977 |
[The lignoicaine test in the diagnosis of pain in the lumbosacral spine].
Topics: Adult; Back Pain; Diagnosis, Differential; Female; Humans; Injections, Intra-Articular; Lidocaine; L | 1985 |
Relief of sciatic radicular pain by sciatic nerve block.
Topics: Adult; Analgesia, Epidural; Female; Humans; Lidocaine; Male; Middle Aged; Nerve Block; Pain Measurem | 1988 |
The diagnostic accuracy of spinal nerve injection studies. Their role in the evaluation of recurrent sciatica.
Topics: Adult; Aged; Female; Follow-Up Studies; Humans; Laminectomy; Lidocaine; Male; Middle Aged; Nerve Blo | 1985 |
Amours M d',+AMOURS M: [Treatment of acute lumbalgia].
Topics: Acute Disease; Back Pain; Drug Synergism; Female; Humans; Hydrocortisone; Injections; Intervertebral | 1969 |
Nerve-root injection: a method for evaluating the etiology of sciatica.
Topics: Contrast Media; Humans; Lidocaine; Myelography; Prognosis; Sciatica; Spinal Cord Compression; Spinal | 1974 |
Peroneal sensory neuropathy entrapment syndrome.
Topics: Adult; Aged; Arthritis; Diagnosis, Differential; Female; Humans; Intermittent Claudication; Lidocain | 1972 |
Lumbar epidural injection for the treatment of chronic sciatica.
Topics: Adult; Age Factors; Anesthesia, Spinal; Chronic Disease; Female; Follow-Up Studies; Humans; Hydrocor | 1970 |
Epidural-saline therapy in lumbosciatic syndrome.
Topics: Adult; Aged; Female; Humans; Lidocaine; Male; Middle Aged; Sciatica | 1966 |