lidocaine has been researched along with Rhinitis in 5 studies
Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.
Rhinitis: Inflammation of the NASAL MUCOSA, the mucous membrane lining the NASAL CAVITIES.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Background Postoperative nausea and vomiting (PONV) are among the most common unpleasant and distressing adverse events following surgery under general anesthesia." | 2.87 | The Role of Endoscopic Sphenopalatine Ganglion Block on Nausea and Vomiting After Sinus Surgery. ( Abubaker, AK; Al-Qudah, MA, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (80.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tangbumrungtham, N | 1 |
| Hwang, PH | 1 |
| Maul, X | 1 |
| Borchard, NA | 1 |
| Dholakia, SS | 1 |
| Patel, ZM | 1 |
| Nayak, JV | 1 |
| Choby, G | 1 |
| Abubaker, AK | 1 |
| Al-Qudah, MA | 1 |
| Goh, LC | 1 |
| Arvin, B | 1 |
| Zulkiflee, AB | 1 |
| Prepageran, N | 1 |
| Mishra, AK | 1 |
| Sinha, VR | 1 |
| Nilakantan, A | 1 |
| Singh, DK | 1 |
| Koo Ng, NK | 1 |
| Young, D | 1 |
| McGarry, GW | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effects of Adrenaline Infiltration on Surgical Field of View in Endoscopic Sinus Surgery[NCT05867342] | Phase 4 | 40 participants (Actual) | Interventional | 2017-05-12 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
(NCT05867342)
Timeframe: intraoperatively (up to 3 hours)
| Intervention | minutes (Mean) |
|---|---|
| 1:1000 Epinephrine Plus Saline | 72.05 |
| 1:1000 Epinephrine Plus Infiltration of 1% Lidocaine With 1:100,000 Epinephrine | 54.23 |
(NCT05867342)
Timeframe: intraoperatively (up to 3 hours)
| Intervention | mL (Mean) |
|---|---|
| 1:1000 Epinephrine Plus Saline | 95.25 |
| 1:1000 Epinephrine Plus Infiltration of 1% Lidocaine With 1:100,000 Epinephrine | 91.63 |
Participants indicated number of days with bloody nasal discharge postoperatively using the 1-week postoperative bleeding questionnaire. (NCT05867342)
Timeframe: 1 week after the surgery (up to 2 minutes to complete assessment)
| Intervention | days (Mean) |
|---|---|
| 1:1000 Epinephrine Plus Saline | 2.85 |
| 1:1000 Epinephrine Plus Infiltration of 1% Lidocaine With 1:100,000 Epinephrine | 2.73 |
A pledget is a small wad of absorbent material used to stop bleeding. (NCT05867342)
Timeframe: intraoperatively (up to 3 hours)
| Intervention | pledgets (Mean) |
|---|---|
| 1:1000 Epinephrine Plus Saline | 3.25 |
| 1:1000 Epinephrine Plus Infiltration of 1% Lidocaine With 1:100,000 Epinephrine | 2.63 |
Number of nostrils with excessive fresh bleeding postoperatively using the 1-week postoperative bleeding questionnaire. Continuous fresh bleeding was defined as bleeding for over 15 minutes. (NCT05867342)
Timeframe: 1 week after the surgery (up to 2 minutes to complete assessment)
| Intervention | nostrils (Count of Units) |
|---|---|
| 1:1000 Epinephrine Plus Saline | 7 |
| 1:1000 Epinephrine Plus Infiltration of 1% Lidocaine With 1:100,000 Epinephrine | 5 |
Grading of postoperative bloody discharge postoperatively assessed by patient using the 1-week postoperative bleeding questionnaire. Scores range from 0 (no bleeding) to 5 (continuous heavy bleeding necessitating medical care). (NCT05867342)
Timeframe: 1 week after the surgery (up to 2 minutes to complete assessment)
| Intervention | score on a scale (Mean) |
|---|---|
| 1:1000 Epinephrine Plus Saline | 2.38 |
| 1:1000 Epinephrine Plus Infiltration of 1% Lidocaine With 1:100,000 Epinephrine | 2.2 |
The video recording of the endoscopic sinus surgery of the participant was graded by another otolaryngology specialist postoperatively and graded according to Wormald Surgical Field Grading Scale. Scores range from 0 (no bleeding) to 10 (severe bleeding with nasal cavity filling rapidly). (NCT05867342)
Timeframe: postoperatively (approximately 20 minutes to assess)
| Intervention | score on a scale (Mean) |
|---|---|
| 1:1000 Epinephrine Plus Saline | 3.54 |
| 1:1000 Epinephrine Plus Infiltration of 1% Lidocaine With 1:100,000 Epinephrine | 3.23 |
3 trials available for lidocaine and Rhinitis
| Article | Year |
|---|---|
The effect of topical epinephrine 1:1000 with and without infiltration of 1% lidocaine with epinephrine 1:100,000 on endoscopic surgical field visualization: a double-blind randomized controlled study.
Topics: Administration, Topical; Adult; Aged; Anesthetics, Local; Blood Loss, Surgical; Chronic Disease; Dou | 2020 |
The Role of Endoscopic Sphenopalatine Ganglion Block on Nausea and Vomiting After Sinus Surgery.
Topics: Adult; Anesthesia, General; Chronic Disease; Double-Blind Method; Drug Combinations; Endoscopy; Epin | 2018 |
Lidocaine/Phenylephrine Nasal Spray versus Nebulization Prior to Nasoendoscopy: A Randomized Controlled Trial.
Topics: Administration, Intranasal; Drug Combinations; Endoscopy; Female; Follow-Up Studies; Humans; Lidocai | 2018 |
2 other studies available for lidocaine and Rhinitis
| Article | Year |
|---|---|
Rhinosinusitis associated with post-dental extraction chronic oroantral fistula: outcomes of non-surgical management comprising antibiotics and local decongestion therapy.
Topics: Administration, Topical; Adult; Aged; Anesthetics, Local; Anti-Bacterial Agents; Chronic Disease; Fe | 2016 |
Reversible nasal airway obstruction: does change in nasal peak inspiratory flow following decongestion predict response to topical steroids in chronic rhinosinusitis patients?
Topics: Administration, Intranasal; Adult; Aged; Chronic Disease; Humans; Lidocaine; Middle Aged; Nasal Deco | 2012 |