Page last updated: 2024-10-28

lidocaine and Rhinitis

lidocaine has been researched along with Rhinitis in 5 studies

Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.

Rhinitis: Inflammation of the NASAL MUCOSA, the mucous membrane lining the NASAL CAVITIES.

Research Excerpts

ExcerptRelevanceReference
"Background Postoperative nausea and vomiting (PONV) are among the most common unpleasant and distressing adverse events following surgery under general anesthesia."2.87The Role of Endoscopic Sphenopalatine Ganglion Block on Nausea and Vomiting After Sinus Surgery. ( Abubaker, AK; Al-Qudah, MA, 2018)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (80.00)24.3611
2020's1 (20.00)2.80

Authors

AuthorsStudies
Tangbumrungtham, N1
Hwang, PH1
Maul, X1
Borchard, NA1
Dholakia, SS1
Patel, ZM1
Nayak, JV1
Choby, G1
Abubaker, AK1
Al-Qudah, MA1
Goh, LC1
Arvin, B1
Zulkiflee, AB1
Prepageran, N1
Mishra, AK1
Sinha, VR1
Nilakantan, A1
Singh, DK1
Koo Ng, NK1
Young, D1
McGarry, GW1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effects of Adrenaline Infiltration on Surgical Field of View in Endoscopic Sinus Surgery[NCT05867342]Phase 440 participants (Actual)Interventional2017-05-12Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Duration of Surgery

(NCT05867342)
Timeframe: intraoperatively (up to 3 hours)

Interventionminutes (Mean)
1:1000 Epinephrine Plus Saline72.05
1:1000 Epinephrine Plus Infiltration of 1% Lidocaine With 1:100,000 Epinephrine54.23

Estimated Blood Loss During Surgery

(NCT05867342)
Timeframe: intraoperatively (up to 3 hours)

InterventionmL (Mean)
1:1000 Epinephrine Plus Saline95.25
1:1000 Epinephrine Plus Infiltration of 1% Lidocaine With 1:100,000 Epinephrine91.63

Number of Days With Postoperative Bloody Nasal Discharge

Participants indicated number of days with bloody nasal discharge postoperatively using the 1-week postoperative bleeding questionnaire. (NCT05867342)
Timeframe: 1 week after the surgery (up to 2 minutes to complete assessment)

Interventiondays (Mean)
1:1000 Epinephrine Plus Saline2.85
1:1000 Epinephrine Plus Infiltration of 1% Lidocaine With 1:100,000 Epinephrine2.73

Number of Extra Pledgets Used

A pledget is a small wad of absorbent material used to stop bleeding. (NCT05867342)
Timeframe: intraoperatively (up to 3 hours)

Interventionpledgets (Mean)
1:1000 Epinephrine Plus Saline3.25
1:1000 Epinephrine Plus Infiltration of 1% Lidocaine With 1:100,000 Epinephrine2.63

Number of Nostrils With Continuous Fresh Bleeding

Number of nostrils with excessive fresh bleeding postoperatively using the 1-week postoperative bleeding questionnaire. Continuous fresh bleeding was defined as bleeding for over 15 minutes. (NCT05867342)
Timeframe: 1 week after the surgery (up to 2 minutes to complete assessment)

Interventionnostrils (Count of Units)
1:1000 Epinephrine Plus Saline7
1:1000 Epinephrine Plus Infiltration of 1% Lidocaine With 1:100,000 Epinephrine5

Postoperative Bloody Discharge Grading Score

Grading of postoperative bloody discharge postoperatively assessed by patient using the 1-week postoperative bleeding questionnaire. Scores range from 0 (no bleeding) to 5 (continuous heavy bleeding necessitating medical care). (NCT05867342)
Timeframe: 1 week after the surgery (up to 2 minutes to complete assessment)

Interventionscore on a scale (Mean)
1:1000 Epinephrine Plus Saline2.38
1:1000 Epinephrine Plus Infiltration of 1% Lidocaine With 1:100,000 Epinephrine2.2

Surgical Field Grading Score

The video recording of the endoscopic sinus surgery of the participant was graded by another otolaryngology specialist postoperatively and graded according to Wormald Surgical Field Grading Scale. Scores range from 0 (no bleeding) to 10 (severe bleeding with nasal cavity filling rapidly). (NCT05867342)
Timeframe: postoperatively (approximately 20 minutes to assess)

Interventionscore on a scale (Mean)
1:1000 Epinephrine Plus Saline3.54
1:1000 Epinephrine Plus Infiltration of 1% Lidocaine With 1:100,000 Epinephrine3.23

Trials

3 trials available for lidocaine and Rhinitis

ArticleYear
The effect of topical epinephrine 1:1000 with and without infiltration of 1% lidocaine with epinephrine 1:100,000 on endoscopic surgical field visualization: a double-blind randomized controlled study.
    International forum of allergy & rhinology, 2020, Volume: 10, Issue:2

    Topics: Administration, Topical; Adult; Aged; Anesthetics, Local; Blood Loss, Surgical; Chronic Disease; Dou

2020
The Role of Endoscopic Sphenopalatine Ganglion Block on Nausea and Vomiting After Sinus Surgery.
    American journal of rhinology & allergy, 2018, Volume: 32, Issue:5

    Topics: Adult; Anesthesia, General; Chronic Disease; Double-Blind Method; Drug Combinations; Endoscopy; Epin

2018
Lidocaine/Phenylephrine Nasal Spray versus Nebulization Prior to Nasoendoscopy: A Randomized Controlled Trial.
    Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 2018, Volume: 159, Issue:4

    Topics: Administration, Intranasal; Drug Combinations; Endoscopy; Female; Follow-Up Studies; Humans; Lidocai

2018

Other Studies

2 other studies available for lidocaine and Rhinitis

ArticleYear
Rhinosinusitis associated with post-dental extraction chronic oroantral fistula: outcomes of non-surgical management comprising antibiotics and local decongestion therapy.
    The Journal of laryngology and otology, 2016, Volume: 130, Issue:6

    Topics: Administration, Topical; Adult; Aged; Anesthetics, Local; Anti-Bacterial Agents; Chronic Disease; Fe

2016
Reversible nasal airway obstruction: does change in nasal peak inspiratory flow following decongestion predict response to topical steroids in chronic rhinosinusitis patients?
    The Journal of laryngology and otology, 2012, Volume: 126, Issue:12

    Topics: Administration, Intranasal; Adult; Aged; Chronic Disease; Humans; Lidocaine; Middle Aged; Nasal Deco

2012