lidocaine has been researched along with Retinoblastoma in 2 studies
Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.
Retinoblastoma: A malignant tumor arising from the nuclear layer of the retina that is the most common primary tumor of the eye in children. The tumor tends to occur in early childhood or infancy and may be present at birth. The majority are sporadic, but the condition may be transmitted as an autosomal dominant trait. Histologic features include dense cellularity, small round polygonal cells, and areas of calcification and necrosis. An abnormal pupil reflex (leukokoria); NYSTAGMUS, PATHOLOGIC; STRABISMUS; and visual loss represent common clinical characteristics of this condition. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, p2104)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Lidocaine is a local anesthetic and anti‑arrhythmic drug, and has been reported to possess anti‑tumor properties." | 5.51 | Lidocaine inhibits the progression of retinoblastoma in vitro and in vivo by modulating the miR‑520a‑3p/EGFR axis. ( Mu, X; Wang, L; Xia, W; Yu, D; Zhou, X, 2019) |
| "Lidocaine is a local anesthetic and anti‑arrhythmic drug, and has been reported to possess anti‑tumor properties." | 1.51 | Lidocaine inhibits the progression of retinoblastoma in vitro and in vivo by modulating the miR‑520a‑3p/EGFR axis. ( Mu, X; Wang, L; Xia, W; Yu, D; Zhou, X, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Xia, W | 1 |
| Wang, L | 1 |
| Yu, D | 1 |
| Mu, X | 1 |
| Zhou, X | 1 |
| Massey, GV | 1 |
| Pedigo, S | 1 |
| Dunn, NL | 1 |
| Grossman, NJ | 1 |
| Russell, EC | 1 |
2 other studies available for lidocaine and Retinoblastoma
| Article | Year |
|---|---|
Lidocaine inhibits the progression of retinoblastoma in vitro and in vivo by modulating the miR‑520a‑3p/EGFR axis.
Topics: Apoptosis; Base Sequence; Cell Line, Tumor; Cell Proliferation; Child; Child, Preschool; Disease Pro | 2019 |
Continuous lidocaine infusion for the relief of refractory malignant pain in a terminally ill pediatric cancer patient.
Topics: Analgesics, Opioid; Child, Preschool; Female; Humans; Injections, Spinal; Lidocaine; Neoplasm Metast | 2002 |