Page last updated: 2024-10-28

lidocaine and Radiculopathy

lidocaine has been researched along with Radiculopathy in 55 studies

Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.

Radiculopathy: Disease involving a spinal nerve root (see SPINAL NERVE ROOTS) which may result from compression related to INTERVERTEBRAL DISK DISPLACEMENT; SPINAL CORD INJURIES; SPINAL DISEASES; and other conditions. Clinical manifestations include radicular pain, weakness, and sensory loss referable to structures innervated by the involved nerve root.

Research Excerpts

ExcerptRelevanceReference
"Determine the efficacy of intravenous lidocaine when compared to ketorolac for the treatment of acute radicular low back pain."9.19Intravenous lidocaine for the emergency department treatment of acute radicular low back pain, a randomized controlled trial. ( Danish, DC; Dos Santos, F; Makela, M; Riffenburgh, RH; Shimada, M; Tanen, DA, 2014)
"Cervical radiculopathy is a mixed pain syndrome characterized by neuropathic, skeletal and myofascial pain."5.42[Conservative treatment of cervical radiculopathy with 5% lidocaine medicated plaster]. ( Mattozzi, I, 2015)
"Determine the efficacy of intravenous lidocaine when compared to ketorolac for the treatment of acute radicular low back pain."5.19Intravenous lidocaine for the emergency department treatment of acute radicular low back pain, a randomized controlled trial. ( Danish, DC; Dos Santos, F; Makela, M; Riffenburgh, RH; Shimada, M; Tanen, DA, 2014)
", periradicular injection of Lidocaine and triamcinolone) for lumbar monoradiculopathy in patients with a mild neurological deficit in National Institute of Traumatology & Orthopaedic Rehabilitation (NITOR), Dhaka, Bangladesh from March 2014 to December 2014."3.83The Role of Selective Nerve Root Block in the Treatment of Lumbar Radicular Leg Pain. ( Akter, S; Alam, S; Jonayed, SA; Kamruzzaman, M; Saha, MK, 2016)
"Our study suggests that needle instillation of steroid and lidocaine is effective in short-term pain occurs in different painful spine conditions (Sy cervicale, lumbare and radiculopathy)."3.80Short-term results after local application of steroids and anesthetics in patients with painful spine conditions. ( Aganovic, D; Biscevic, M; Hadziahmetovic, NV; Kadic, A, 2014)
" Prior to their first injection, subjects rated the pain intensity of a standardized subcutaneous (SQ) injection of lidocaine prior to the full dose."3.79Does pain score in response to a standardized subcutaneous local anesthetic injection predict epidural steroid injection outcomes in patients with lumbosacral radiculopathy? A prospective correlational study. ( Buckenmaier, CC; Chen, L; Christo, PJ; Cohen, SP; Erdek, MA; Griffith, SR; Gupta, A; Kurihara, C; Mao, J; Strassels, SA; Vu, TN, 2013)
"Forty-four patients with mild cervical stenosis and 30 patients with moderate to severe cervical stenosis were consecutively enrolled into two groups."1.91Ultrasound-guided nerve hydrodissection of cervical nerve roots for cervical radicular pain in patients with mild and moderate to severe stenosis: a retrospective cohort study. ( Lin, CH; Wu, CY; Yen, YS, 2023)
"Thirty-eight injections did not provoke referred pain symptoms and were excluded from further analysis."1.51Induced lumbosacral radicular symptom referral patterns: a descriptive study. ( Furman, MB; Johnson, SC, 2019)
"Cervical radiculopathy is a mixed pain syndrome characterized by neuropathic, skeletal and myofascial pain."1.42[Conservative treatment of cervical radiculopathy with 5% lidocaine medicated plaster]. ( Mattozzi, I, 2015)
"Pharmaceutical treatments for radiculopathy include opioid, antiinflammatory (steroidal and nonsteroidal), neuromodulating, topical, and adjuvant treatments."1.37Pharmaceutical therapy for radiculopathy. ( Cheng, DS; Kennedy, DJ; Visco, CJ, 2011)
"L3 radiculopathy was characterized by various lower limb pain and neurologic deficit."1.35Characteristics of L3 nerve root radiculopathy. ( Ebara, S; Hashidate, H; Hirabayashi, H; Kato, H; Misawa, H; Mitsui, K; Ogihara, N; Takahashi, J; Tashiro, A; Wakabayashi, S, 2009)
"Lidocaine (Xylocaine) was used in the diagnostic injections and a mixture of lidocaine and betamethasone was used in the therapeutic injections."1.33Complications and side effects of cervical and lumbosacral selective nerve root injections. ( Garvin, C; Huston, CW; Slipman, CW, 2005)

Research

Studies (55)

TimeframeStudies, this research(%)All Research%
pre-19901 (1.82)18.7374
1990's9 (16.36)18.2507
2000's20 (36.36)29.6817
2010's23 (41.82)24.3611
2020's2 (3.64)2.80

Authors

AuthorsStudies
Lin, CH1
Yen, YS1
Wu, CY1
Makkar, JK1
Gourav, KKP1
Jain, K1
Singh, PM1
Dhatt, SS1
Sachdeva, N1
Bhadada, S1
Falsafi, M1
Baghianimoghadam, B1
Bahrami-Freiduni, M1
Esmaeilnejad-Ganji, SM1
McCormick, ZL1
Nelson, A1
Kendall, MC1
McCarthy, RJ1
Nagpal, G1
Walega, DR1
Park, D1
Furman, MB1
Johnson, SC1
Ko, S1
Chae, S1
Choi, W1
Kwon, J1
Li, K1
Zhang, T1
Gao, K1
Lv, CL1
Tagowski, M1
Lewandowski, Z1
Hodler, J1
Spiegel, T1
Goerres, GW1
Mallinson, PI1
Tapping, CR1
Bartlett, R1
Maliakal, P1
Tanen, DA1
Shimada, M1
Danish, DC1
Dos Santos, F1
Makela, M1
Riffenburgh, RH1
Hadziahmetovic, NV1
Aganovic, D1
Kadic, A1
Biscevic, M1
Woo, JH1
Park, HS1
Mattozzi, I1
Kim, ED1
Roh, MS1
Park, JJ1
Jo, D1
Jonayed, SA1
Kamruzzaman, M1
Saha, MK1
Alam, S1
Akter, S1
Gungor, S1
Aiyer, R1
Fish, DE2
Kobayashi, HW1
Chang, TL1
Pham, Q2
Hirabayashi, H1
Takahashi, J1
Hashidate, H1
Ogihara, N1
Tashiro, A1
Misawa, H1
Ebara, S1
Mitsui, K1
Wakabayashi, S1
Kato, H1
Laiq, N1
Khan, MN1
Iqbal, MJ1
Khan, S1
Murata, Y1
Kato, Y1
Miyamoto, K1
Takahashi, K1
Buchanan, DD1
J MacIvor, F1
Visco, CJ1
Cheng, DS1
Kennedy, DJ1
Chung, SG1
Manchikanti, L3
Singh, V2
Cash, KA3
Pampati, V3
Damron, KS1
Boswell, MV1
Park, KD1
Lee, J1
Jee, H1
Park, Y1
Wargo, BW1
Malla, Y1
Falco, FJ1
Cohen, SP1
Mao, J1
Vu, TN1
Strassels, SA1
Gupta, A1
Erdek, MA1
Christo, PJ1
Kurihara, C1
Griffith, SR1
Buckenmaier, CC1
Chen, L1
Avidan, A1
Gomori, M1
Davidson, E1
Kelekis, AD1
Martin, JB1
Somon, T1
Wetzel, SG1
Dietrich, PY1
Ruefenacht, DA1
Karasek, M1
Bogduk, N1
Rodrigues-Filho, R1
Campos, MM1
Ferreira, J1
Santos, AR1
Bertelli, JA1
Calixto, JB1
de Jong, RH2
Dougherty, P1
Bajwa, S1
Burke, J1
Dishman, JD1
Huston, CW1
Slipman, CW1
Garvin, C1
Schaufele, MK1
Hatch, L1
Jones, W1
Botwin, K1
Brown, LA1
Fishman, M1
Rao, S1
Shirazi, EP1
Albrecht, A1
Hogg, M1
Robinson, S1
Hampl, KF1
Schneider, MC1
Pargger, H1
Gut, J1
Drewe, J1
Drasner, K1
Lambert, DH1
Lambert, LA1
Strichartz, GR1
Grange, C1
Bright, S1
Douglas, J1
Ramasamy, D1
Eadie, R1
Mardirosoff, C1
Dumont, L1
Mattys, M1
Soto, G1
Zennaro, H1
Dousset, V1
Viaud, B1
Allard, M1
Dehais, J1
Sénégas, J1
Caillé, JM1
Panadero, A1
Monedero, P1
Fernandez-Liesa, JI1
Percaz, J1
Olavide, I1
Iribarren, MJ1
Arregui Martínez de Lejarza, LM1
Alonso Chico, A1
Pacheco Jiménez, JA1
Sánchez García, ML1
Johnson, ME1
Murtagh, R1
Vad, VB1
Bhat, AL1
Lutz, GE1
Cammisa, F1
Canady, J1
Hargrove, M1
Ganz, A1
Derby, R1
Kine, G1
Saal, JA1
Reynolds, J1
Goldthwaite, N1
White, AH1
Hsu, K1
Zucherman, J1
Warfield, CA1
Crews, DA1

Clinical Trials (5)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Erector Spinae Plane Block Versus Transforaminal Epidural Injection in Chronic Discogenic Low Back Pain[NCT04212845]60 participants (Anticipated)Interventional2020-01-02Recruiting
The Study of Perioperative Intravenous Infusion of Lidocaine on Postoperative Analgesia in Patients Undergoing Single-port Thoracoscopic[NCT04043624]Phase 480 participants (Anticipated)Interventional2019-08-01Recruiting
A Prospective Randomized Comparative Trial of Targeted Injection Via a Transforaminal Approach With Dexamethasone Versus an Epidural Catheter Via an Interlaminar Approach With Particulate Steroid for the Treatment of Cervical Radicular Pain[NCT03382821]Phase 4120 participants (Actual)Interventional2017-09-15Completed
Using Inflammatory Biomarkers and EMG Results to Predict Epidural Injection Response in Patients Diagnosed With Lumbar Stenosis[NCT03511053]11 participants (Actual)Interventional2017-12-19Completed
Comparison of the Efficacy Between Transforaminal Steroid Epidural Injection and Epidural Neuroplasty for the Treatment of Herniated Lumbar Disc:A Single Center, Controlled Clinical Trial[NCT03101033]92 participants (Actual)Interventional2015-05-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

The Percentage of Participants With Reduction of 50% or More of Neck and Arm Pain NRS Score

The Percentage of Participants with Reduction of 50% or More of Neck and Arm Pain NRS score (NCT03382821)
Timeframe: 1 month follow up

Interventionpercentage of participants (Number)
Transforaminal ESI With Dexamethasone49.1
Interlaminar Catheter-targeted ESI With Triamcinolone68.5

"The Percentage of Participants Reporting Patient Global Impression of Change Score of 6-7 (Indicating Much Improved and Very Much Improved)"

"Patient Global Impression of Change is a scale which measures participant reported satisfaction after an intervention. The outcome was measured as the percent of patients reporting a PGIC score of 6-7 (indicating much improved and very much improved)" (NCT03382821)
Timeframe: 1 month, 3 month, 6 month, and 1 year follow up

,
Interventionpercentage of participants (Number)
One monthThree monthsSix monthsOne year
Transforaminal Catheter-targeted ESI With Triamcinolone59575361
Transforaminal ESI With Dexamethasone41425557

Neck Disability Index-5

Percentage of patients with >30% improvement in Neck Disability Index-5 score. (NCT03382821)
Timeframe: 1 month, 3 month, 6 month, and 1 year follow up

,
Interventionpercentage of participants (Number)
One monthThree monthSix monthOne year
Transforaminal Catheter-targeted ESI With Triamcinolone62585660
Transforaminal ESI With Dexamethasone48565547

Percentage of Participants Reporting >6.8 Reduction on the Medication Quantification Scale III

The Medication Quantification Scale (MQS) is an instrument used for clinical and research applications for quantifying medication regimen use in chronic pain populations. A 6.8 point reduction is considered equivalent to 10 morphine eqivalents. (NCT03382821)
Timeframe: 1 month, 3 month, 6 month, and 1 year follow up

,
Interventionpercentage of participants (Number)
One monthThree monthSix monthOne year
Transforaminal Catheter-targeted ESI With Triamcinolone1917198
Transforaminal ESI With Dexamethasone1620157

Pain Disability Questionnaire

Measures how pain is affecting the patients lifestyle on a scale from 0 to 10 as defined by each question. The questionnaire contains 15 questions that each range on a scale form 0 to 10. The total score of the questionnaire ranges from 0 to 150. Lower values represent a better outcome. (NCT03511053)
Timeframe: Change between baseline, 1 month and 2 months post injection

Interventionscore on a scale (Mean)
Average at baselineAverage at 1 monthAverage at 2 monthsAverage at 1 month changeAverage at 2 month change
All Participants77.553.364.327.316.2

Swiss Spinal Stenosis Questionnaire

Measures how pain due to spinal stenosis is effected the patient based on quality of life/pain questions and satisfaction questions for months 1 and 2 (no scales are used) SSSQ scores are reported in percentages 0-100%, higher scores indicate worse outcomes. (NCT03511053)
Timeframe: Change between baseline, 1 month and 2 months post injection

InterventionPercentage (Mean)
Average at baselineAverage at 1 monthAverage at 2 monthsAverage at 1 month changeAverage at 2 month change
All Participants64.153.253.511.710.3

Visual Analogue Scale

Number rating of back/leg pain from 0 to 10, 0 being no pain/discomfort, 10 being extreme pain/discomfort (NCT03511053)
Timeframe: Change between baseline, 1 month and 2 months post injection

Interventionscore on a scale (Mean)
Average at baselineAverage at 1 monthAverage at 2 monthsAverage 1 month changeAverage 2 month change
All Participants6.25.05.00.81

Functional Status Assessed by Oswestry Disability Index

ODI (Oswestry disability index) consists of 10 subscales, which evaluates pain intensity, and functional satus of personal care, lifting, walking, sitting, standing, sleeping, sex, social life, traveling. Each subscales range from 0 to 5, with the higher score indicating more severe functional damage. the ODI score ranges from 0 to 100. it equals the sum of all the subscales and divided by 50. If the patients answers 9 subscale questions, then the total sum should be divided by 45, and by this analogy. (NCT03101033)
Timeframe: at one-month post-treatment

Interventionunits on a scale (Mean)
Epidural Neuroplasty Group29.11
Transforaminal Steroid Injection Group35.02

Functional Status Assessed by Oswestry Disability Index

ODI (Oswestry disability index) consists of 10 subscales, which evaluates pain intensity, and functional satus of personal care, lifting, walking, sitting, standing, sleeping, sex, social life, traveling. Each subscales range from 0 to 5, with the higher score indicating more severe functional damage. the ODI score ranges from 0 to 100. it equals the sum of all the subscales and divided by 50. If the patients answers 9 subscale questions, then the total sum should be divided by 45, and by this analogy. (NCT03101033)
Timeframe: at six-month post-treatment

Interventionunits on a scale (Mean)
Epidural Neuroplasty Group30.52
Transforaminal Steroid Injection Group46.39

Functional Status Assessed by Oswestry Disability Index

ODI (Oswestry disability index) consists of 10 subscales, which evaluates pain intensity, and functional satus of personal care, lifting, walking, sitting, standing, sleeping, sex, social life, traveling. Each subscales range from 0 to 5, with the higher score indicating more severe functional damage. the ODI score ranges from 0 to 100. it equals the sum of all the subscales and divided by 50. If the patients answers 9 subscale questions, then the total sum should be divided by 45, and by this analogy. (NCT03101033)
Timeframe: at three-month post-treatment

Interventionunits on a scale (Mean)
Epidural Neuroplasty Group28.93
Transforaminal Steroid Injection Group39.82

Functional Status Assessed by Oswestry Disability Index

ODI (Oswestry disability index) consists of 10 subscales, which evaluates pain intensity, and functional satus of personal care, lifting, walking, sitting, standing, sleeping, sex, social life, traveling. Each subscales range from 0 to 5, with the higher score indicating more severe functional damage. the ODI score ranges from 0 to 100. it equals the sum of all the subscales and divided by 50. If the patients answers 9 subscale questions, then the total sum should be divided by 45, and by this analogy. (NCT03101033)
Timeframe: before treatment

Interventionunits on a scale (Mean)
Epidural Neuroplasty Group53.85
Transforaminal Steroid Injection Group57.84

Pain Assessed by Visual Analogue Scale

VAS (Visual analogue scale), with the highest score of 10, representing the most severe pain one could experience, and the lowest score of 0, representing no pain at all. The higher score means more severe pain. (NCT03101033)
Timeframe: at one-month post-treatment

Interventionunits on a scale (Mean)
Epidural Neuroplasty Group2.37
Transforaminal Steroid Injection Group2.35

Pain Assessed by Visual Analogue Scale

VAS (Visual analogue scale), with the highest score of 10, representing the most severe pain one could experience, and the lowest score of 0, representing no pain at all. The higher score means more severe pain. (NCT03101033)
Timeframe: at six-month post-treatment

Interventionunits on a scale (Mean)
Epidural Neuroplasty Group2.81
Transforaminal Steroid Injection Group4.06

Pain Assessed by Visual Analogue Scale

VAS (Visual analogue scale), with the highest score of 10, representing the most severe pain one could experience, and the lowest score of 0, representing no pain at all. The higher score means more severe pain. (NCT03101033)
Timeframe: at three-month post-treatment

Interventionunits on a scale (Mean)
Epidural Neuroplasty Group2.19
Transforaminal Steroid Injection Group3.25

Pain Assessed by Visual Analogue Scale

VAS (Visual analogue scale), with the highest score of 10, representing the most severe pain one could experience, and the lowest score of 0, representing no pain at all. The higher score means more severe pain. (NCT03101033)
Timeframe: before treatment

Interventionunits on a scale (Mean)
Epidural Neuroplasty Group5.63
Transforaminal Steroid Injection Group5.92

Reviews

2 reviews available for lidocaine and Radiculopathy

ArticleYear
Potential neurotoxicity of spinal anesthesia with lidocaine.
    Mayo Clinic proceedings, 2000, Volume: 75, Issue:9

    Topics: Adverse Drug Reaction Reporting Systems; Anesthesia, Spinal; Anesthetics, Local; Animals; Bupivacain

2000
The art and science of nerve root and facet blocks.
    Neuroimaging clinics of North America, 2000, Volume: 10, Issue:3

    Topics: Anesthetics, Local; Humans; Lidocaine; Nerve Block; Peripheral Nerves; Radiculopathy; Spinal Disease

2000

Trials

15 trials available for lidocaine and Radiculopathy

ArticleYear
Transforaminal Versus Lateral Parasagittal Versus Midline Interlaminar Lumbar Epidural Steroid Injection for Management of Unilateral Radicular Lumbar Pain: A Randomized Double-Blind Trial.
    Pain physician, 2019, Volume: 22, Issue:6

    Topics: Adult; Double-Blind Method; Epidural Space; Female; Humans; Injections, Epidural; Lidocaine; Low Bac

2019
Examining the Accuracy of Ultrasound-Guided Lumbar Transforaminal Injection Controlled by Fluoroscopic Imaging in Patients with Lumbar Radiculopathy: A Modified Technique.
    Turkish neurosurgery, 2021, Volume: 31, Issue:4

    Topics: Adult; Aged; Analgesia, Epidural; Catheterization; Female; Fluoroscopy; Humans; Injections, Epidural

2021
Prolonged pain reducing effect of sodium hyaluronate-carboxymethyl cellulose solution in the selective nerve root block (SNRB) of lumbar radiculopathy: a prospective, double-blind, randomized controlled clinical trial.
    The spine journal : official journal of the North American Spine Society, 2019, Volume: 19, Issue:4

    Topics: Adrenal Cortex Hormones; Adult; Anesthetics, Local; Bupivacaine; Carboxymethylcellulose Sodium; Doub

2019
The Utility of Diagnostic Transforaminal Epidural Injection in Selective Percutaneous Endoscopic Lumbar Discectomy for Multilevel Disc Herniation with Monoradicular Symptom: A Prospective Randomized Control Study.
    World neurosurgery, 2019, Volume: 126

    Topics: Adult; Anesthetics, Local; Diskectomy, Percutaneous; Female; Humans; Injections, Epidural; Intervert

2019
Intravenous lidocaine for the emergency department treatment of acute radicular low back pain, a randomized controlled trial.
    The Journal of emergency medicine, 2014, Volume: 47, Issue:1

    Topics: Acute Pain; Administration, Intravenous; Adult; Anesthetics, Local; Cyclooxygenase Inhibitors; Doubl

2014
Cervical transforaminal epidural block using low-dose local anesthetic: a prospective, randomized, double-blind study.
    Pain medicine (Malden, Mass.), 2015, Volume: 16, Issue:1

    Topics: Analgesia, Epidural; Anesthetics, Local; Cervical Vertebrae; Dexamethasone; Dose-Response Relationsh

2015
Comparison of the Ventral Epidural Spreading in Modified Interlaminar Approach and Transforaminal Approach: A Randomized, Double-Blind Study.
    Pain medicine (Malden, Mass.), 2016, Volume: 17, Issue:9

    Topics: Anesthetics, Local; Double-Blind Method; Female; Humans; Hyaluronoglucosaminidase; Injections, Epidu

2016
Comparison of Epidural Steroid Injections with conservative management in patients with lumbar radiculopathy.
    Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2009, Volume: 19, Issue:9

    Topics: Adult; Anesthetics, Local; Anti-Inflammatory Agents; Female; Humans; Injections, Epidural; Lidocaine

2009
Clinical study of low back pain and radicular pain pathways by using l2 spinal nerve root infiltration: a randomized, controlled, clinical trial.
    Spine, 2009, Sep-01, Volume: 34, Issue:19

    Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Dexamet

2009
A randomized, controlled, double-blind trial of fluoroscopic caudal epidural injections in the treatment of lumbar disc herniation and radiculitis.
    Spine, 2011, Nov-01, Volume: 36, Issue:23

    Topics: Adult; Anesthesia, Caudal; Anesthetics, Local; Betamethasone; Double-Blind Method; Drug Therapy, Com

2011
Kambin triangle versus the supraneural approach for the treatment of lumbar radicular pain.
    American journal of physical medicine & rehabilitation, 2012, Volume: 91, Issue:12

    Topics: Aged; Analgesia, Epidural; Anesthetics, Local; Anti-Inflammatory Agents; Drug Therapy, Combination;

2012
Management of chronic pain of cervical disc herniation and radiculitis with fluoroscopic cervical interlaminar epidural injections.
    International journal of medical sciences, 2012, Volume: 9, Issue:6

    Topics: Adult; Anesthetics, Local; Betamethasone; Cervical Vertebrae; Chronic Pain; Double-Blind Method; Fem

2012
The role of fluoroscopic interlaminar epidural injections in managing chronic pain of lumbar disc herniation or radiculitis: a randomized, double-blind trial.
    Pain practice : the official journal of World Institute of Pain, 2013, Volume: 13, Issue:7

    Topics: Adult; Anesthetics, Local; Anti-Inflammatory Agents; Betamethasone; Chronic Pain; Double-Blind Metho

2013
A similar incidence of transient neurologic symptoms after spinal anesthesia with 2% and 5% lidocaine.
    Anesthesia and analgesia, 1996, Volume: 83, Issue:5

    Topics: Adult; Anesthesia, Spinal; Anesthetics, Local; Female; Genitalia, Female; Humans; Incidence; Lidocai

1996
Transforaminal epidural steroid injections in lumbosacral radiculopathy: a prospective randomized study.
    Spine, 2002, Jan-01, Volume: 27, Issue:1

    Topics: Adult; Anesthetics, Local; Betamethasone; Contrast Media; Fluoroscopy; Follow-Up Studies; Hospitals,

2002

Other Studies

38 other studies available for lidocaine and Radiculopathy

ArticleYear
Ultrasound-guided nerve hydrodissection of cervical nerve roots for cervical radicular pain in patients with mild and moderate to severe stenosis: a retrospective cohort study.
    Scientific reports, 2023, 08-24, Volume: 13, Issue:1

    Topics: Animals; Coleoptera; Constriction, Pathologic; Drug-Related Side Effects and Adverse Reactions; Huma

2023
Does Cervical Interlaminar Epidural Steroid Injection with Low-Dose Lidocaine Cause Objective Upper Extremity Weakness? A Preliminary Study.
    Pain medicine (Malden, Mass.), 2017, Dec-01, Volume: 18, Issue:12

    Topics: Adult; Anesthetics, Local; Anti-Inflammatory Agents; Arm; Female; Glucocorticoids; Hand Strength; Hu

2017
Ultrasound-Guided S1 Transforaminal Epidural Injection Using the In-Plane Approach and Color Doppler Imaging.
    American journal of physical medicine & rehabilitation, 2018, Volume: 97, Issue:3

    Topics: Anesthetics, Local; Female; Humans; Injections, Epidural; Intervertebral Disc Displacement; Lidocain

2018
Induced lumbosacral radicular symptom referral patterns: a descriptive study.
    The spine journal : official journal of the North American Spine Society, 2019, Volume: 19, Issue:1

    Topics: Adult; Anesthetics, Local; Back Pain; Female; Humans; Injections, Epidural; Lidocaine; Lumbosacral R

2019
Pain reduction after lumbar epidural injections using particulate versus non-particulate steroids: intensity of the baseline pain matters.
    European radiology, 2019, Volume: 29, Issue:7

    Topics: Adult; Aged; Back Pain; Bupivacaine; Dexamethasone; Female; Glucocorticoids; Humans; Injections, Epi

2019
Factors that affect the efficacy of fluoroscopically guided selective spinal nerve root block in the treatment of radicular pain: a prospective cohort study.
    Canadian Association of Radiologists journal = Journal l'Association canadienne des radiologistes, 2013, Volume: 64, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Local; Anti-Inflammatory Agents; Bupivacaine; Cohort St

2013
Short-term results after local application of steroids and anesthetics in patients with painful spine conditions.
    Medical archives (Sarajevo, Bosnia and Herzegovina), 2014, Volume: 68, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Local; Disability Evaluation; Female; Humans; Instillat

2014
[Conservative treatment of cervical radiculopathy with 5% lidocaine medicated plaster].
    Minerva medica, 2015, Volume: 106, Issue:1

    Topics: Administration, Topical; Anesthetics, Local; Casts, Surgical; Female; Humans; Lidocaine; Male; Mesot

2015
The Role of Selective Nerve Root Block in the Treatment of Lumbar Radicular Leg Pain.
    Mymensingh medical journal : MMJ, 2016, Volume: 25, Issue:1

    Topics: Adult; Aged; Bangladesh; Constriction, Pathologic; Humans; Intervertebral Disc Displacement; Leg; Li

2016
A Computed Tomography-Guided Demonstration of the Unilateral Distribution of Low-Volume Epidural Injectate.
    Pain practice : the official journal of World Institute of Pain, 2017, Volume: 17, Issue:7

    Topics: Aged; Epidural Space; Female; Fluoroscopy; Humans; Injections, Epidural; Intraoperative Neurophysiol

2017
MRI prediction of therapeutic response to epidural steroid injection in patients with cervical radiculopathy.
    American journal of physical medicine & rehabilitation, 2009, Volume: 88, Issue:3

    Topics: Adult; Aged; Anesthetics, Local; Disability Evaluation; Female; Glucocorticoids; Humans; Injections,

2009
Characteristics of L3 nerve root radiculopathy.
    Surgical neurology, 2009, Volume: 72, Issue:1

    Topics: Aged; Aged, 80 and over; Anesthetics, Local; Anti-Inflammatory Agents; Decompression, Surgical; Disk

2009
A role for intravenous lidocaine in severe cancer-related neuropathic pain at the end-of-life.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2010, Volume: 18, Issue:7

    Topics: Aged; Anesthetics, Local; Back Pain; Bone Neoplasms; Humans; Infusions, Intravenous; Kidney Neoplasm

2010
Pharmaceutical therapy for radiculopathy.
    Physical medicine and rehabilitation clinics of North America, 2011, Volume: 22, Issue:1

    Topics: Adrenal Cortex Hormones; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non

2011
Convulsion caused by a lidocaine test in cervical transforaminal epidural steroid injection.
    PM & R : the journal of injury, function, and rehabilitation, 2011, Volume: 3, Issue:7

    Topics: Anesthetics, Local; Contrast Media; Female; Humans; Injections, Epidural; Injections, Spinal; Iopami

2011
Does pain score in response to a standardized subcutaneous local anesthetic injection predict epidural steroid injection outcomes in patients with lumbosacral radiculopathy? A prospective correlational study.
    Pain medicine (Malden, Mass.), 2013, Volume: 14, Issue:3

    Topics: Adult; Aged; Anesthetics, Local; Female; Glucocorticoids; Humans; Injections, Epidural; Injections,

2013
Nerve root inflammation demonstrated by magnetic resonance imaging in a patient with transient neurologic symptoms after intrathecal injection of lidocaine.
    Anesthesiology, 2002, Volume: 97, Issue:1

    Topics: Anesthesia, Spinal; Anesthetics, Local; Humans; Injections, Spinal; Lidocaine; Magnetic Resonance Im

2002
Radicular pain after vertebroplasty: compression or irritation of the nerve root? Initial experience with the "cooling system".
    Spine, 2003, Jul-15, Volume: 28, Issue:14

    Topics: Adult; Aged; Anesthetics, Local; Bone Cements; Humans; Lidocaine; Middle Aged; Orthopedic Procedures

2003
Temporary neurologic deficit after cervical transforaminal injection of local anesthetic.
    Pain medicine (Malden, Mass.), 2004, Volume: 5, Issue:2

    Topics: Adrenal Cortex Hormones; Anesthetics, Local; Cervical Vertebrae; Female; Humans; Injections, Epidura

2004
Pharmacological characterisation of the rat brachial plexus avulsion model of neuropathic pain.
    Brain research, 2004, Aug-27, Volume: 1018, Issue:2

    Topics: Acetates; Amines; Analgesics; Analysis of Variance; Animals; Brachial Plexus; Brachial Plexus Neurop

2004
Troubling incidence of lidocaine radiculotoxicity (TNS) in volunteers.
    Anesthesia and analgesia, 2004, Volume: 99, Issue:4

    Topics: Anesthetics, Local; Humans; Lidocaine; Procaine; Radiculopathy

2004
Overnight stay lowers incidence of lidocaine radiculotoxicity ("TNS").
    Anesthesia and analgesia, 2004, Volume: 99, Issue:4

    Topics: Anesthesia, Spinal; Anesthetics, Local; Early Ambulation; Hospitalization; Humans; Length of Stay; L

2004
Spinal manipulation postepidural injection for lumbar and cervical radiculopathy: a retrospective case series.
    Journal of manipulative and physiological therapeutics, 2004, Volume: 27, Issue:7

    Topics: Adult; Aged; Anesthetics, Local; Anti-Inflammatory Agents; Combined Modality Therapy; Female; Humans

2004
Complications and side effects of cervical and lumbosacral selective nerve root injections.
    Archives of physical medicine and rehabilitation, 2005, Volume: 86, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Local; Anti-Inflammatory Agents; Betamethasone; Female;

2005
Interlaminar versus transforaminal epidural injections for the treatment of symptomatic lumbar intervertebral disc herniations.
    Pain physician, 2006, Volume: 9, Issue:4

    Topics: Anesthetics, Local; Anti-Inflammatory Agents; Case-Control Studies; Humans; Injections, Epidural; In

2006
Fluoroscopically guided caudal epidural steroid injections in degenerative lumbar spine stenosis.
    Pain physician, 2007, Volume: 10, Issue:4

    Topics: Aged; Aged, 80 and over; Analgesia, Epidural; Back Pain; Cohort Studies; Female; Fluoroscopy; Follow

2007
The use of electromyography to predict functional outcome following transforaminal epidural spinal injections for lumbar radiculopathy.
    The journal of pain, 2008, Volume: 9, Issue:1

    Topics: Aged; Anesthetics, Local; Disability Evaluation; Drug Combinations; Electromyography; Humans; Inject

2008
Transient radicular irritation as a complication of spinal anaesthesia with hyperbaric 5% lignocaine.
    Anaesthesia and intensive care, 1996, Volume: 24, Issue:4

    Topics: Aged; Anesthesia, Spinal; Anesthetics, Local; Humans; Lidocaine; Male; Pain, Postoperative; Radiculo

1996
Radicular irritation after spinal anesthesia.
    Anesthesiology, 1996, Volume: 85, Issue:5

    Topics: Anesthesia, Spinal; Anesthetics, Local; Bupivacaine; Humans; Lidocaine; Radiculopathy

1996
Radicular irritation with 2% lignocaine spinal.
    Anaesthesia and intensive care, 1997, Volume: 25, Issue:1

    Topics: Adult; Anesthesia, Spinal; Anesthetics, Local; Female; Humans; Lidocaine; Pain, Postoperative; Radic

1997
Transient dysaesthesia following spinal anaesthesia with 2% lignocaine.
    Anaesthesia and intensive care, 1997, Volume: 25, Issue:1

    Topics: Anesthesia, Spinal; Anesthetics, Local; Humans; Lidocaine; Male; Middle Aged; Pain, Postoperative; R

1997
Transient radicular irritation followed by meningitis after spinal anesthesia.
    Acta anaesthesiologica Belgica, 1996, Volume: 47, Issue:4

    Topics: Adult; Anesthesia, Spinal; Diagnosis, Differential; Humans; Lidocaine; Male; Meningitis, Aseptic; Me

1996
Periganglionic foraminal steroid injections performed under CT control.
    AJNR. American journal of neuroradiology, 1998, Volume: 19, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents; Female; Ganglia, Spinal; Humans; Hydrocort

1998
Repeated transient neurological symptoms after spinal anaesthesia with hyperbaric 5% lidocaine.
    British journal of anaesthesia, 1998, Volume: 81, Issue:3

    Topics: Aged; Anesthesia, Spinal; Anesthetics, Local; Cystoscopy; Humans; Lidocaine; Male; Radiculopathy

1998
[Transitory radicular irritation syndrome after the use of hyperbaric lidocaine].
    Revista espanola de anestesiologia y reanimacion, 2000, Volume: 47, Issue:2

    Topics: Adult; Anesthesia, Spinal; Anesthetics, Local; Humans; Lidocaine; Male; Radiculopathy

2000
Transient radiculopathy after 5% lidocaine or 0.75% bupivacaine spinal anesthesia in 3 surgical positions.
    AANA journal, 2001, Volume: 69, Issue:5

    Topics: Adult; Aged; Anesthesia, Spinal; Anesthetics, Local; Bupivacaine; Female; Humans; Lidocaine; Male; M

2001
Response to steroid and duration of radicular pain as predictors of surgical outcome.
    Spine, 1992, Volume: 17, Issue:6 Suppl

    Topics: Betamethasone; Delayed-Action Preparations; Humans; Lidocaine; Nerve Compression Syndromes; Predicti

1992
Epidural steroid injection as a predictor of surgical outcome.
    Surgery, gynecology & obstetrics, 1987, Volume: 164, Issue:5

    Topics: Back Pain; Chymopapain; Humans; Injections, Spinal; Intervertebral Disc Chemolysis; Lidocaine; Methy

1987