Page last updated: 2024-10-28

lidocaine and Pyrexia

lidocaine has been researched along with Pyrexia in 25 studies

Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.

Research Excerpts

ExcerptRelevanceReference
"Lidocaine reduces pain that occurs upon the intravenous injection of propofol."9.22Comparison of the effects of lidocaine pre-administration and local warming of the intravenous access site on propofol injection pain: Randomized, double-blind controlled trial. ( Jeong, M; Yoon, H, 2016)
"Lidocaine reduces pain that occurs upon the intravenous injection of propofol."5.22Comparison of the effects of lidocaine pre-administration and local warming of the intravenous access site on propofol injection pain: Randomized, double-blind controlled trial. ( Jeong, M; Yoon, H, 2016)
" A 41-year-old man developed a fever and liver injury after undergoing internal hemorrhoid treatment with a submucosal injection of ALTA with lidocaine."3.85Liver injury after aluminum potassium sulfate and tannic acid treatment of hemorrhoids. ( Akasu, T; Fushiya, N; Hagiwara, N; Hirose, Y; Imai, N; Iwaku, A; Kawashima, R; Kijima, H; Kinoshita, A; Kobayashi, G; Kobayashi, H; Koike, K; Saruta, M; Shibata, K; Yokota, T; Yoshikawa, K, 2017)
" This case report describes a patient in whom a typical Brugada ECG pattern developed during fever and could be reproduced at normal body temperature by administration of pilsicainide."3.72Brugada-like electrocardiographic pattern unmasked by fever. ( Kanmatsuse, K; Kofune, T; Masaki, R; Okubo, K; Okumura, Y; Oshikawa, N; Ozawa, Y; Saito, S; Sugimura, H; Takagi, Y; Wakita, R; Watanabe, I; Yamada, T, 2004)
"Acupuncture has been used to treat drug addiction by nicotine, alcohol, cocaine and morphine."1.37Effect of bee venom acupuncture on methamphetamine-induced hyperactivity, hyperthermia and Fos expression in mice. ( Kim, HW; Kim, KW; Kwon, YB; Li, J, 2011)
"Two patients had cardiac arrest before sclerosis could be attempted."1.29Pericardial sclerosis as the primary management of malignant pericardial effusion and cardiac tamponade. ( Maher, EA; Shepherd, FA; Todd, TJ, 1996)
"Pretreatment with procaine did not prevent the onset of the condition and the administration of procaine when muscle rigidity was present failed to prevent a fatal outcome."1.25Further studies of porcine malignant hyperthermia. ( Hall, LW; Trim, CM; Woolf, N, 1972)

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-199010 (40.00)18.7374
1990's1 (4.00)18.2507
2000's7 (28.00)29.6817
2010's5 (20.00)24.3611
2020's2 (8.00)2.80

Authors

AuthorsStudies
Nociti, V1
Picarelli, C1
Losavio, FA1
Reale, G1
Giuliano, G1
Della Marca, G1
Tumbarello, M1
Arias, MA1
Pachón, M1
Loughlin, G1
Yoshikawa, K1
Kawashima, R1
Hirose, Y1
Shibata, K1
Akasu, T1
Hagiwara, N1
Yokota, T1
Imai, N1
Iwaku, A1
Kobayashi, G1
Kobayashi, H1
Kinoshita, A1
Fushiya, N1
Kijima, H1
Koike, K1
Saruta, M1
Indra, S1
Arora, R1
Jeong, M1
Yoon, H1
Kim, KW1
Kim, HW1
Li, J1
Kwon, YB1
Kamata, M1
Tada, Y1
Yazawa, N1
Watanabe, T1
Kikuchi, K1
Sato, S1
Botwin, KP1
Castellanos, R1
Rao, S1
Hanna, AF1
Torres-Ramos, FM1
Gruber, RD1
Bouchlas, CG1
Fuoco, GS1
FROMMEL, E1
FLEURY, C1
VON LEDEBUR, I1
BEGUIN, M1
Wakita, R1
Watanabe, I1
Okumura, Y1
Yamada, T1
Takagi, Y1
Kofune, T1
Okubo, K1
Masaki, R1
Sugimura, H1
Oshikawa, N1
Saito, S1
Ozawa, Y1
Kanmatsuse, K1
Morita, H1
Zipes, DP1
Morita, ST1
Wu, J2
Deschênes, I1
Laurita, KR1
Maher, EA1
Shepherd, FA1
Todd, TJ1
Javedan, SP1
Ellsworth, K1
Smith, K1
Fisher, RS1
Crandall, CG1
Vongpatanasin, W1
Victor, RG1
Wallenstein, MC1
Strobel, GE2
Farber, HI1
Catt, PB1
Hogg, DF1
Clunie, GJ1
Hardie, IR1
Hall, LW1
Trim, CM1
Woolf, N1
Gruhl, D1
Bianchi, CP1
Olurin, O1

Clinical Trials (4)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Will Warm Patch on the Injecting Site Decrease the Injection Pain Induced by Propofol[NCT04555980]120 participants (Actual)Interventional2020-03-20Completed
Do Cervical Interlaminar Epidural Steroid Injections With Low-dose Lidocaine Cause Transient Objective Upper Extremity Weakness? A Prospective Randomized Controlled Trial[NCT03127137]Phase 4123 participants (Actual)Interventional2018-08-01Completed
Do Cervical Interlaminar Epidural Steroid Injections With Low-dose Lidocaine Cause Transient Objective Upper Extremity Weakness? A Prospective Randomized[NCT03382925]Phase 416 participants (Actual)Interventional2017-12-20Terminated (stopped due to Not enough cervical interlaminar patients who meet criteria in order to meet recruitment goals.)
Study of Dexmedetomidine for the Reversal of Cocaine's Effects on Myocardial Perfusion[NCT01927640]Early Phase 1115 participants (Actual)Interventional2013-02-01Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Change in Strength in Both Groups After CESI.

Change in strength in both groups greater than or equal to 20% weakness in one or more myotomes 30 minutes after CESI using a hand held Dynamometer. (NCT03127137)
Timeframe: 30 minutes after the CESI procedure

,
InterventionParticipants (Count of Participants)
Yes, greater or equal to 20% weakness in greater or equal to 1 or more myotomeNo, greater or equal to 20% weakness in greater or equal to 1 or more myotome
Experimental Group 1 With Lidocaine2535
Experimental Group 2 With Saline3030

Trials

2 trials available for lidocaine and Pyrexia

ArticleYear
Comparison of the effects of lidocaine pre-administration and local warming of the intravenous access site on propofol injection pain: Randomized, double-blind controlled trial.
    International journal of nursing studies, 2016, Volume: 61

    Topics: Double-Blind Method; Fever; Humans; Lidocaine; Pain; Propofol; Prospective Studies

2016
Mechanism of cocaine-induced hyperthermia in humans.
    Annals of internal medicine, 2002, Jun-04, Volume: 136, Issue:11

    Topics: Adult; Blood Pressure; Body Temperature Regulation; Cocaine; Cross-Over Studies; Double-Blind Method

2002

Other Studies

23 other studies available for lidocaine and Pyrexia

ArticleYear
Posterior Reversible Encephalopathy Syndrome After Intramuscular Oxygen-Ozone Therapy.
    The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 2020, Volume: 47, Issue:3

    Topics: Aged; Anesthetics, Local; Back Muscles; Blindness, Cortical; Cervical Vertebrae; Confusion; Diffusio

2020
New Onset Recurrent Syncope Triggered by Fever.
    Circulation, 2020, 03-17, Volume: 141, Issue:11

    Topics: Amiodarone; Coronary Angiography; Drug Therapy, Combination; Electric Countershock; Electrocardiogra

2020
Liver injury after aluminum potassium sulfate and tannic acid treatment of hemorrhoids.
    World journal of gastroenterology, 2017, Jul-21, Volume: 23, Issue:27

    Topics: Adult; Alum Compounds; Chemical and Drug Induced Liver Injury; Fever; Hemorrhoids; Humans; Injection

2017
Fever, Genital Pain, and Genital Ulcers.
    Clinical pediatrics, 2016, Volume: 55, Issue:5

    Topics: Anesthetics, Local; Anti-Inflammatory Agents; Child; Clobetasol; Diagnosis, Differential; Female; Fe

2016
Effect of bee venom acupuncture on methamphetamine-induced hyperactivity, hyperthermia and Fos expression in mice.
    Brain research bulletin, 2011, Jan-15, Volume: 84, Issue:1

    Topics: Acupuncture Therapy; Adrenergic alpha-2 Receptor Antagonists; Anesthetics, Local; Animals; Bee Venom

2011
Drug fever caused by eutectic mixture of local anesthetic cream.
    Journal of investigational allergology & clinical immunology, 2011, Volume: 21, Issue:5

    Topics: Debridement; Drug Hypersensitivity; Drug Interactions; Female; Fever; Humans; Leg Ulcer; Lidocaine;

2011
Complications of fluoroscopically guided interlaminar cervical epidural injections.
    Archives of physical medicine and rehabilitation, 2003, Volume: 84, Issue:5

    Topics: Adult; Age Distribution; Aged; Cervical Vertebrae; Chi-Square Distribution; Female; Fever; Fluorosco

2003
Complications of fluoroscopically guided interlaminar cervical epidural injections.
    Archives of physical medicine and rehabilitation, 2003, Volume: 84, Issue:5

    Topics: Adult; Age Distribution; Aged; Cervical Vertebrae; Chi-Square Distribution; Female; Fever; Fluorosco

2003
Complications of fluoroscopically guided interlaminar cervical epidural injections.
    Archives of physical medicine and rehabilitation, 2003, Volume: 84, Issue:5

    Topics: Adult; Age Distribution; Aged; Cervical Vertebrae; Chi-Square Distribution; Female; Fever; Fluorosco

2003
Complications of fluoroscopically guided interlaminar cervical epidural injections.
    Archives of physical medicine and rehabilitation, 2003, Volume: 84, Issue:5

    Topics: Adult; Age Distribution; Aged; Cervical Vertebrae; Chi-Square Distribution; Female; Fever; Fluorosco

2003
[Deviations in the pharmacodynamic action of various drugs by hypo- and hyperthermia. 2].
    Helvetica physiologica et pharmacologica acta, 1962, Volume: Suppl 12

    Topics: Acetylcholine; Aminobutyrates; Amphetamine; Amphetamines; Atropine; Chlordiazepoxide; Chlorpromazine

1962
Brugada-like electrocardiographic pattern unmasked by fever.
    Japanese heart journal, 2004, Volume: 45, Issue:1

    Topics: Adult; Body Temperature; Bundle-Branch Block; Electrocardiography; Fever; Humans; Lidocaine; Male; S

2004
Temperature modulation of ventricular arrhythmogenicity in a canine tissue model of Brugada syndrome.
    Heart rhythm, 2007, Volume: 4, Issue:2

    Topics: Action Potentials; Animals; Body Temperature; Brugada Syndrome; Disease Models, Animal; Dogs; Electr

2007
How can a single mutation cause such arrhythmic havoc?
    Heart rhythm, 2007, Volume: 4, Issue:2

    Topics: Action Potentials; Animals; Body Temperature; Brugada Syndrome; Disease Models, Animal; Dogs; Electr

2007
Pericardial sclerosis as the primary management of malignant pericardial effusion and cardiac tamponade.
    The Journal of thoracic and cardiovascular surgery, 1996, Volume: 112, Issue:3

    Topics: Adult; Aged; Anesthetics, Local; Anti-Bacterial Agents; Arrhythmias, Cardiac; Bacterial Infections;

1996
Gamma oscillation underlies hyperthermia-induced epileptiform-like spikes in immature rat hippocampal slices.
    BMC neuroscience, 2001, Volume: 2

    Topics: Action Potentials; Anesthetics, Local; Animals; Biological Clocks; Cortical Spreading Depression; El

2001
Summaries for patients. Body heat management in people using cocaine.
    Annals of internal medicine, 2002, Jun-04, Volume: 136, Issue:11

    Topics: Adult; Body Temperature Regulation; Cocaine; Double-Blind Method; Esophagus; Female; Fever; Humans;

2002
Temperature response to morphine in paralyzed cats.
    European journal of pharmacology, 1978, Jun-01, Volume: 49, Issue:3

    Topics: Animals; Cats; Female; Fever; Lidocaine; Male; Morphine; Motor Activity; Paralysis

1978
Treatment of anaesthetic-induced malignant hyperpyrexia.
    Lancet (London, England), 1971, Jan-02, Volume: 1, Issue:7688

    Topics: Anesthesia, Local; Anesthetics; Calcium; Fever; Humans; Lidocaine; Muscle Contraction; Procainamide

1971
Fever, vomiting, and liver dysfunction with procainamide therapy.
    Postgraduate medicine, 1974, Volume: 56, Issue:1

    Topics: Ampicillin; Blood; Chemical and Drug Induced Liver Injury; Digitalis; Drug Hypersensitivity; Female;

1974
Retained biliary calculi: removal by a simple non-operative technique.
    Annals of surgery, 1974, Volume: 180, Issue:2

    Topics: Adult; Aged; Cholangiography; Cholelithiasis; Contrast Media; Duodenum; Female; Fever; Humans; Infec

1974
Further studies of porcine malignant hyperthermia.
    British medical journal, 1972, Apr-15, Volume: 2, Issue:5806

    Topics: Acidosis; Anesthesia, General; Anesthetics; Animals; Chloroform; Cyclopropanes; Fever; Halothane; Ke

1972
[Malignant hyperthermie--a case report].
    Der Anaesthesist, 1972, Volume: 21, Issue:5

    Topics: Anesthesia, General; Child; Diazepam; Female; Fever; Humans; Hypothermia, Induced; Lidocaine

1972
An in-vitro model of anesthetic hypertonic hyperpyrexia, halothane--caffeine-induced muscle contractures: prevention of contracture by procainamide.
    Anesthesiology, 1971, Volume: 35, Issue:5

    Topics: Anesthesia, Inhalation; Animals; Anura; Caffeine; Culture Techniques; Drug Synergism; Fever; Halotha

1971
Teething troubles.
    British medical journal, 1970, Apr-11, Volume: 2, Issue:5701

    Topics: Diarrhea, Infantile; Female; Fever; Humans; Infant; Lidocaine; Male; Seizures; Tooth Eruption

1970
Cortical blindness following convulsions and fever in Nigerian children.
    Pediatrics, 1970, Volume: 46, Issue:1

    Topics: Anti-Bacterial Agents; Anticonvulsants; Blindness; Blood Transfusion; Bronchopneumonia; Cerebral Cor

1970