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lidocaine and Pre-Eclampsia

lidocaine has been researched along with Pre-Eclampsia in 11 studies

Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.

Pre-Eclampsia: A complication of PREGNANCY, characterized by a complex of symptoms including maternal HYPERTENSION and PROTEINURIA with or without pathological EDEMA. Symptoms may range between mild and severe. Pre-eclampsia usually occurs after the 20th week of gestation, but may develop before this time in the presence of trophoblastic disease.

Research Excerpts

ExcerptRelevanceReference
"The effect of preeclampsia on the binding of lidocaine to serum proteins was studied in 25 term parturients with severe preeclampsia and in 21 normal parturients serving as controls."5.27Lidocaine protein binding in preeclampsia. ( Bottorff, MB; Boucher, BA; Hoon, TJ; Pieper, JA; Ramanathan, J; Sibai, BM, 1987)
" There were no significant differences between normotensive and preeclamptic patients in the total dose of lidocaine, peak maternal plasma concentration, volume of distribution, maternal elimination half-life and umbilical vein/maternal vein ratios."5.27The pharmacokinetics and maternal and neonatal effects of epidural lidocaine in preeclampsia. ( Bottorff, M; Jeter, JN; Khalil, M; Ramanathan, J; Sibai, BM, 1986)
"Thrombocytopenia is considered a relative contraindication to the administration of regional anesthesia."1.30Safe epidural analgesia in thirty parturients with platelet counts between 69,000 and 98,000 mm(-3). ( Beilin, Y; Comerford, M; Zahn, J, 1997)
"The effect of preeclampsia on the binding of lidocaine to serum proteins was studied in 25 term parturients with severe preeclampsia and in 21 normal parturients serving as controls."1.27Lidocaine protein binding in preeclampsia. ( Bottorff, MB; Boucher, BA; Hoon, TJ; Pieper, JA; Ramanathan, J; Sibai, BM, 1987)
" There were no significant differences between normotensive and preeclamptic patients in the total dose of lidocaine, peak maternal plasma concentration, volume of distribution, maternal elimination half-life and umbilical vein/maternal vein ratios."1.27The pharmacokinetics and maternal and neonatal effects of epidural lidocaine in preeclampsia. ( Bottorff, M; Jeter, JN; Khalil, M; Ramanathan, J; Sibai, BM, 1986)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19906 (54.55)18.7374
1990's5 (45.45)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Pue, AF1
Beilin, Y1
Zahn, J1
Comerford, M1
Bédard, JM1
Richardson, MG1
Wissler, RN1
Gautam, PL1
Kathuria, S1
Kaul, TK1
Janisch, H1
Leodolter, S1
Neumark, J1
Philipp, K1
Allen, RW1
James, MF1
Uys, PC1
Bottorff, MB1
Pieper, JA1
Boucher, BA1
Hoon, TJ1
Ramanathan, J2
Sibai, BM2
Heller, PJ1
Goodman, C1
Bottorff, M1
Jeter, JN1
Khalil, M1
Hansen, N1
Arens, JF1

Trials

1 trial available for lidocaine and Pre-Eclampsia

ArticleYear
Attenuation of the pressor response to tracheal intubation in hypertensive proteinuric pregnant patients by lignocaine, alfentanil and magnesium sulphate.
    British journal of anaesthesia, 1991, Volume: 66, Issue:2

    Topics: Alfentanil; Anesthesia, General; Anesthesia, Obstetrical; Blood Pressure; Cesarean Section; Female;

1991

Other Studies

10 other studies available for lidocaine and Pre-Eclampsia

ArticleYear
Periarterial lidocaine/hydralazine aids arterial catheter insertion in patients with preeclampsia.
    Anesthesiology, 1993, Volume: 79, Issue:2

    Topics: Arteries; Catheterization, Peripheral; Female; Humans; Hydralazine; Lidocaine; Pre-Eclampsia; Pregna

1993
Safe epidural analgesia in thirty parturients with platelet counts between 69,000 and 98,000 mm(-3).
    Anesthesia and analgesia, 1997, Volume: 85, Issue:2

    Topics: Analgesia, Epidural; Analgesia, Obstetrical; Anesthesia, Epidural; Anesthesia, Obstetrical; Anesthet

1997
Epidural anesthesia in a parturient with a lumboperitoneal shunt.
    Anesthesiology, 1999, Volume: 90, Issue:2

    Topics: Adult; Anesthesia, Epidural; Anesthetics, Intravenous; Anesthetics, Local; Bupivacaine; Female; Fent

1999
Infiltration block for caesarean section in a morbidly obese parturient.
    Acta anaesthesiologica Scandinavica, 1999, Volume: 43, Issue:5

    Topics: Adult; Anesthesia, Obstetrical; Anesthetics, Local; Cesarean Section; Edema; Female; Fetal Death; Hu

1999
[The influence of the continuous epidural anaesthesia on uteroplacental blood flow (author's transl)].
    Zeitschrift fur Geburtshilfe und Perinatologie, 1978, Volume: 182, Issue:5

    Topics: Anesthesia, Epidural; Anesthesia, Obstetrical; Anesthetics, Local; Female; Humans; Infusions, Parent

1978
Lidocaine protein binding in preeclampsia.
    European journal of clinical pharmacology, 1987, Volume: 31, Issue:6

    Topics: Blood Proteins; Blood Specimen Collection; Female; Humans; Lidocaine; Orosomucoid; Pre-Eclampsia; Pr

1987
Use of local anesthetics with epinephrine for epidural anesthesia in preeclampsia.
    Anesthesiology, 1986, Volume: 65, Issue:2

    Topics: Adolescent; Adult; Anesthesia, Epidural; Anesthesia, Local; Bupivacaine; Diazepam; Epinephrine; Fema

1986
The pharmacokinetics and maternal and neonatal effects of epidural lidocaine in preeclampsia.
    Anesthesia and analgesia, 1986, Volume: 65, Issue:2

    Topics: Adult; Anesthesia, Epidural; Anesthesia, Obstetrical; Cesarean Section; Female; Fetus; Humans; Infan

1986
[Hypertension with pudendal block].
    Ugeskrift for laeger, 1969, Sep-25, Volume: 131, Issue:39

    Topics: Adult; Anesthesia, Obstetrical; Blood Pressure; Female; Humans; Lidocaine; Methods; Norepinephrine;

1969
Epidural and caudal anesthesia for complicated obstetrics.
    Southern medical journal, 1970, Volume: 63, Issue:1

    Topics: Anesthesia, Obstetrical; Anesthesia, Spinal; Delivery, Obstetric; Female; Heart Failure; Humans; Lid

1970