lidocaine has been researched along with Polyneuropathies in 6 studies
Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.
Polyneuropathies: Diseases of multiple peripheral nerves simultaneously. Polyneuropathies usually are characterized by symmetrical, bilateral distal motor and sensory impairment with a graded increase in severity distally. The pathological processes affecting peripheral nerves include degeneration of the axon, myelin or both. The various forms of polyneuropathy are categorized by the type of nerve affected (e.g., sensory, motor, or autonomic), by the distribution of nerve injury (e.g., distal vs. proximal), by nerve component primarily affected (e.g., demyelinating vs. axonal), by etiology, or by pattern of inheritance.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To investigate the analgesic efficacy and safety of 5% lidocaine gel in painful HIV-associated distal sensory polyneuropathy (DSP)." | 5.11 | A randomized controlled trial of 5% lidocaine gel for HIV-associated distal symmetric polyneuropathy. ( Carter, K; Estanislao, L; McArthur, J; Olney, R; Simpson, D, 2004) |
| "Fourteen patients with neuropathic pain (7 with unilateral foot pain due to peripheral nerve injury and 7 with bilateral pain in the feet due to distal polyneuropathy) underwent comprehensive characterization of somatosensory function by quantitative sensory testing." | 1.40 | Primary afferent input critical for maintaining spontaneous pain in peripheral neuropathy. ( Bendtsen, TF; Finnerup, NB; Haroutounian, S; Hasselstrøm, JB; Jensen, TS; Kristensen, AD; Nikolajsen, L, 2014) |
| "Predictors of response to neuropathic pain treatment in patients with painful distal sensory neuropathies are lacking." | 1.33 | Skin biopsy and quantitative sensory testing do not predict response to lidocaine patch in painful neuropathies. ( Barbano, RL; Dworkin, RH; Herrmann, DN; Pannoni, V; Pennella-Vaughan, J, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (16.67) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (66.67) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Haroutounian, S | 1 |
| Nikolajsen, L | 1 |
| Bendtsen, TF | 1 |
| Finnerup, NB | 1 |
| Kristensen, AD | 1 |
| Hasselstrøm, JB | 1 |
| Jensen, TS | 1 |
| Wilder-Smith, EP | 1 |
| Guo, Y | 1 |
| Chow, A | 1 |
| Estanislao, L | 1 |
| Carter, K | 1 |
| McArthur, J | 1 |
| Olney, R | 1 |
| Simpson, D | 1 |
| Herrmann, DN | 1 |
| Pannoni, V | 1 |
| Barbano, RL | 1 |
| Pennella-Vaughan, J | 1 |
| Dworkin, RH | 2 |
| Jensen, MP | 1 |
| Gammaitoni, AR | 1 |
| Olaleye, DO | 1 |
| Galer, BS | 1 |
| Economacos, G | 1 |
| Skountzos, V | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Diode Laser as a Biomarker for Neuropathic Pain of Peripheral Origin.[NCT06030297] | 301 participants (Anticipated) | Interventional | 2022-11-01 | Recruiting | |||
| The Significance of Peripheral Input in Patients With Post Surgery Neuropathic Pain: Evaluation of Trigger Point Anesthesia. A Double-blind, Randomized, Controlled Exploratory Study[NCT04764045] | 12 participants (Anticipated) | Interventional | 2019-11-20 | Recruiting | |||
| Muscular and Cutaneous Dysfunction in Postural Tachycardia Syndrome[NCT04170725] | 15 participants (Actual) | Interventional | 2020-01-10 | Active, not recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 trials available for lidocaine and Polyneuropathies
| Article | Year |
|---|---|
A randomized controlled trial of 5% lidocaine gel for HIV-associated distal symmetric polyneuropathy.
Topics: Anesthetics, Local; Cross-Over Studies; Double-Blind Method; HIV Infections; Humans; Lidocaine; Midd | 2004 |
Symptom profiles differ in patients with neuropathic versus non-neuropathic pain.
Topics: Administration, Topical; Adult; Aged; Anesthetics, Local; Diabetic Neuropathies; Female; Humans; Lid | 2007 |
4 other studies available for lidocaine and Polyneuropathies
| Article | Year |
|---|---|
Primary afferent input critical for maintaining spontaneous pain in peripheral neuropathy.
Topics: Adolescent; Adult; Afferent Pathways; Aged; Aged, 80 and over; Anesthetics, Local; Central Nervous S | 2014 |
Primary afferent input critical for maintaining spontaneous pain in peripheral neuropathy.
Topics: Adolescent; Adult; Afferent Pathways; Aged; Aged, 80 and over; Anesthetics, Local; Central Nervous S | 2014 |
Primary afferent input critical for maintaining spontaneous pain in peripheral neuropathy.
Topics: Adolescent; Adult; Afferent Pathways; Aged; Aged, 80 and over; Anesthetics, Local; Central Nervous S | 2014 |
Primary afferent input critical for maintaining spontaneous pain in peripheral neuropathy.
Topics: Adolescent; Adult; Afferent Pathways; Aged; Aged, 80 and over; Anesthetics, Local; Central Nervous S | 2014 |
Stimulated skin wrinkling for predicting intraepidermal nerve fibre density.
Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Combined; Female; Humans; Immersion; Lidocaine; Lidocai | 2009 |
Skin biopsy and quantitative sensory testing do not predict response to lidocaine patch in painful neuropathies.
Topics: Aged; Anesthetics, Local; Biopsy; Cohort Studies; Epidermis; Female; Humans; Leg; Lidocaine; Male; M | 2006 |
Clinical aspects of high spinal anesthesia in urological surgery on 3012 patients.
Topics: Adult; Aged; Alcoholism; Anesthesia, Spinal; Humans; Hypotension; Lidocaine; Male; Middle Aged; Neur | 1980 |