Page last updated: 2024-10-28

lidocaine and Pituitary Neoplasms

lidocaine has been researched along with Pituitary Neoplasms in 7 studies

Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.

Pituitary Neoplasms: Neoplasms which arise from or metastasize to the PITUITARY GLAND. The majority of pituitary neoplasms are adenomas, which are divided into non-secreting and secreting forms. Hormone producing forms are further classified by the type of hormone they secrete. Pituitary adenomas may also be characterized by their staining properties (see ADENOMA, BASOPHIL; ADENOMA, ACIDOPHIL; and ADENOMA, CHROMOPHOBE). Pituitary tumors may compress adjacent structures, including the HYPOTHALAMUS, several CRANIAL NERVES, and the OPTIC CHIASM. Chiasmal compression may result in bitemporal HEMIANOPSIA.

Research Excerpts

ExcerptRelevanceReference
"During neurosurgery for hypophysary adenoma under general anaesthesia in a prone position, a 34 year-old-women received accidental 6 ml intramucosal injection of lidocaine with naphazoline."3.72[Cardiac arrest and secondary pulmonary oedema following accidental intramucosal injection of naphazoline in an adult]. ( Delalande, JP; Erhmann, S; Réa, D; Tellier, AC; Villeret, I, 2003)
"Lidocaine (1%) was given as 1."1.40Impact of perioperative lidocaine infusion and bis monitorization on remifentanil dosage in hypotensive anesthesia. ( Aypar, U; Erden, A; Uzun, S; Yuce, Y, 2014)
"Lidocaine was much less effective in inhibiting secretion induced by 1 microM phorbol 12-myristate 13-acetate (TPA) or 5 microM forskolin."1.28Lidocaine inhibits prolactin secretion in GH4C1 cells by blocking calcium influx. ( Greer, MA; Sato, N; Wang, X, 1992)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19901 (14.29)18.7374
1990's1 (14.29)18.2507
2000's3 (42.86)29.6817
2010's1 (14.29)24.3611
2020's1 (14.29)2.80

Authors

AuthorsStudies
Konay, AS1
Williams, A1
Chacko, AG1
Singh, G1
Uzun, S1
Yuce, Y1
Erden, A1
Aypar, U1
Ali, Z1
Prabhakar, H1
Bithal, PK1
Dash, HH1
Villeret, I1
Tellier, AC1
Erhmann, S1
Réa, D1
Delalande, JP1
Abou-Madi, MN1
Trop, D1
Barnes, J1
Arai, T1
Okada, K1
Yamaguchi, T1
Sakuma, A1
Wang, X1
Sato, N1
Greer, MA1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effect of Dexmedetomidine as Anesthetic Coadjuvant on Plasmatic Cortisol Response in Transsphenoidal Surgery for Pituitary Tumors[NCT02549768]Phase 440 participants (Anticipated)Interventional2015-09-30Recruiting
A Prospective, Randomized Controlled Study to Compare the Effect of Sevoflurane and Propofol for Maintenance of Anesthesia on Postoperative Recovery After Transsphenoidal Resection of Pituitary Adenoma[NCT05822817]Phase 4252 participants (Anticipated)Interventional2023-05-03Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

2 trials available for lidocaine and Pituitary Neoplasms

ArticleYear
A Prospective Randomized Trial Comparing Topical Intranasal Lidocaine and Levobupivacaine in Patients Undergoing Endoscopic Binostril Transnasal Transsphenoidal Resection of Pituitary Tumors.
    Journal of neurosurgical anesthesiology, 2021, Volume: 33, Issue:1

    Topics: Administration, Intranasal; Administration, Topical; Adult; Anesthetics, Local; Double-Blind Method;

2021
Bispectral index-guided administration of anesthesia for transsphenoidal resection of pituitary tumors: a comparison of 3 anesthetic techniques.
    Journal of neurosurgical anesthesiology, 2009, Volume: 21, Issue:1

    Topics: Adolescent; Adult; Aged; Anesthesia; Anesthetics, Inhalation; Anesthetics, Intravenous; Anesthetics,

2009
Bispectral index-guided administration of anesthesia for transsphenoidal resection of pituitary tumors: a comparison of 3 anesthetic techniques.
    Journal of neurosurgical anesthesiology, 2009, Volume: 21, Issue:1

    Topics: Adolescent; Adult; Aged; Anesthesia; Anesthetics, Inhalation; Anesthetics, Intravenous; Anesthetics,

2009
Bispectral index-guided administration of anesthesia for transsphenoidal resection of pituitary tumors: a comparison of 3 anesthetic techniques.
    Journal of neurosurgical anesthesiology, 2009, Volume: 21, Issue:1

    Topics: Adolescent; Adult; Aged; Anesthesia; Anesthetics, Inhalation; Anesthetics, Intravenous; Anesthetics,

2009
Bispectral index-guided administration of anesthesia for transsphenoidal resection of pituitary tumors: a comparison of 3 anesthetic techniques.
    Journal of neurosurgical anesthesiology, 2009, Volume: 21, Issue:1

    Topics: Adolescent; Adult; Aged; Anesthesia; Anesthetics, Inhalation; Anesthetics, Intravenous; Anesthetics,

2009

Other Studies

5 other studies available for lidocaine and Pituitary Neoplasms

ArticleYear
Impact of perioperative lidocaine infusion and bis monitorization on remifentanil dosage in hypotensive anesthesia.
    European review for medical and pharmacological sciences, 2014, Volume: 18, Issue:4

    Topics: Adenoma; Adolescent; Adult; Aged; Anesthetics, Combined; Anesthetics, Intravenous; Anesthetics, Loca

2014
[Cardiac arrest and secondary pulmonary oedema following accidental intramucosal injection of naphazoline in an adult].
    Annales francaises d'anesthesie et de reanimation, 2003, Volume: 22, Issue:5

    Topics: Adenoma; Adrenergic alpha-Agonists; Adult; Anesthesia, General; Anesthetics, Local; Blood Pressure;

2003
Aetiology and control of cardiovascular reactions during trans-sphenoidal resection of pituitary microadenomas.
    Canadian Anaesthetists' Society journal, 1980, Volume: 27, Issue:5

    Topics: Adenoma; Adult; Anesthesia; Blood Pressure; Epinephrine; Female; Humans; Hypertension; Lidocaine; Mi

1980
[Endonasal transsphenoidal surgery under local anesthesia for elderly patient with pituitary tumor: case report].
    No shinkei geka. Neurological surgery, 2000, Volume: 28, Issue:11

    Topics: Adenoma; Aged; Aged, 80 and over; Anesthesia, Local; Female; Humans; Hypophysectomy; Lidocaine; Pitu

2000
Lidocaine inhibits prolactin secretion in GH4C1 cells by blocking calcium influx.
    Molecular and cellular endocrinology, 1992, Volume: 87, Issue:1-3

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1992