lidocaine has been researched along with Phantom Limb in 17 studies
Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.
Phantom Limb: Perception of painful and nonpainful phantom sensations that occur following the complete or partial loss of a limb. The majority of individuals with an amputated extremity will experience the impression that the limb is still present, and in many cases, painful. (From Neurol Clin 1998 Nov;16(4):919-36; Brain 1998 Sep;121(Pt 9):1603-30)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Two patients with postamputation stump and phantom limb pain respectively responded favorably to intrathecal fentanyl which temporarily abolished the pain, normalized sensations and produced euphoria without supraspinal effects." | 7.67 | Relief of persistent postamputation stump and phantom limb pain with intrathecal fentanyl. ( Brody, MC; Chabal, C; Jacobson, L, 1989) |
| "Three of 4 patients with accompanying phantom limb pain noted an increase in pain after the injection of gallamine." | 6.66 | Pain responses to perineuromal injection of normal saline, gallamine, and lidocaine in humans. ( Burchiel, KJ; Chabal, C; Jacobson, L; Russell, LC, 1989) |
| "Two patients with postamputation stump and phantom limb pain respectively responded favorably to intrathecal fentanyl which temporarily abolished the pain, normalized sensations and produced euphoria without supraspinal effects." | 3.67 | Relief of persistent postamputation stump and phantom limb pain with intrathecal fentanyl. ( Brody, MC; Chabal, C; Jacobson, L, 1989) |
| "Postamputation phantom pain is notoriously persistent with few validated treatments." | 3.30 | Ultrasound-guided Percutaneous Cryoneurolysis to Treat Chronic Postamputation Phantom Limb Pain: A Multicenter Randomized Controlled Trial. ( Cohen, SP; Eisenach, JC; Fisher, RL; Gabriel, RA; Ilfeld, BM; Liu, L; Mariano, ER; Mascha, EJ; Miller, ME; Prologo, JD; Sessler, DI; Smith, CR; Trescot, AM; Turan, A, 2023) |
| "Eleven subjects had both stump and phantom pains, 11 and 9 subjects had stump and phantom pain alone, respectively." | 2.70 | Analgesic effects of intravenous lidocaine and morphine on postamputation pain: a randomized double-blind, active placebo-controlled, crossover trial. ( Kazim, DA; Raja, SN; Staats, PS; Tella, P; Vaslav, R; Wesselmann, U; Wu, CL, 2002) |
| "Three of 4 patients with accompanying phantom limb pain noted an increase in pain after the injection of gallamine." | 2.66 | Pain responses to perineuromal injection of normal saline, gallamine, and lidocaine in humans. ( Burchiel, KJ; Chabal, C; Jacobson, L; Russell, LC, 1989) |
| "The concept of peripheral myoclonus is not yet fully accepted by the medical community because of the difficulty in establishing a cause-and-effect relationship between trauma and subsequent movement disorders." | 1.35 | Myoclonus of peripheral origin: two case reports. ( Cassim, F; Defebvre, L; Destée, A; Houdayer, E; Kreisler, A; Krystkowiak, P; Tyvaert, L, 2009) |
| "This study shows that phantom sensation is painless and self limiting and that it lasts only for the duration of motor and proprioceptive blockade." | 1.26 | Phanton limb sensation under subarachnoid and epidural analgesia - a comparative clinical study of two hundred cases. ( Chhabra, B; Kamra, GL; Khurana, S; Singh, CV, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (23.53) | 18.7374 |
| 1990's | 3 (17.65) | 18.2507 |
| 2000's | 5 (29.41) | 29.6817 |
| 2010's | 4 (23.53) | 24.3611 |
| 2020's | 1 (5.88) | 2.80 |
| Authors | Studies |
|---|---|
| Ilfeld, BM | 2 |
| Smith, CR | 2 |
| Turan, A | 2 |
| Mariano, ER | 2 |
| Miller, ME | 2 |
| Fisher, RL | 2 |
| Trescot, AM | 2 |
| Cohen, SP | 2 |
| Eisenach, JC | 2 |
| Sessler, DI | 2 |
| Prologo, JD | 2 |
| Mascha, EJ | 2 |
| Liu, L | 2 |
| Gabriel, RA | 2 |
| Buch, NS | 1 |
| Ahlburg, P | 1 |
| Haroutounian, S | 1 |
| Andersen, NT | 1 |
| Finnerup, NB | 1 |
| Nikolajsen, L | 1 |
| Case, LK | 1 |
| Gosavi, R | 1 |
| Ramachandran, VS | 1 |
| Vaso, A | 1 |
| Adahan, HM | 1 |
| Gjika, A | 1 |
| Zahaj, S | 1 |
| Zhurda, T | 1 |
| Vyshka, G | 1 |
| Devor, M | 1 |
| Tyvaert, L | 1 |
| Krystkowiak, P | 1 |
| Cassim, F | 1 |
| Houdayer, E | 1 |
| Kreisler, A | 1 |
| Destée, A | 1 |
| Defebvre, L | 1 |
| Wu, H | 1 |
| Sultana, R | 1 |
| Taylor, KB | 1 |
| Szabo, A | 1 |
| Gandevia, SC | 1 |
| Smith, JL | 1 |
| Crawford, M | 1 |
| Proske, U | 1 |
| Taylor, JL | 1 |
| Lee, E | 1 |
| Donovan, K | 1 |
| Lamacraft, G | 1 |
| Isaacson, SA | 1 |
| Funderburk, M | 1 |
| Yang, J | 1 |
| Wei, F | 1 |
| Zhuo, M | 1 |
| Wu, CL | 1 |
| Tella, P | 1 |
| Staats, PS | 1 |
| Vaslav, R | 1 |
| Kazim, DA | 1 |
| Wesselmann, U | 1 |
| Raja, SN | 1 |
| Khurana, S | 1 |
| Singh, CV | 1 |
| Chhabra, B | 1 |
| Kamra, GL | 1 |
| Jacobson, L | 3 |
| Chabal, C | 3 |
| Brody, MC | 2 |
| Mariano, AJ | 1 |
| Chaney, EF | 1 |
| Russell, LC | 1 |
| Burchiel, KJ | 1 |
| Goodwin, GM | 1 |
| McCloskey, DI | 1 |
| Matthews, PB | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Randomized, Controlled Study to Evaluate the Effectiveness of Farabloc for Chronic Phantom Limb Pain Among Veteran Amputees[NCT00797849] | 57 participants (Actual) | Interventional | 2008-11-30 | Completed | |||
| Use of Tendon Vibration and Mirror for the Improvement of Upper Limb Function and Pain Reduction After Stroke[NCT01010607] | Phase 1/Phase 2 | 30 participants (Anticipated) | Interventional | 2009-11-30 | Not yet recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
7 trials available for lidocaine and Phantom Limb
| Article | Year |
|---|---|
Ultrasound-guided Percutaneous Cryoneurolysis to Treat Chronic Postamputation Phantom Limb Pain: A Multicenter Randomized Controlled Trial.
Topics: Cold Temperature; Humans; Lidocaine; Nerve Block; Phantom Limb; Ultrasonography, Interventional | 2023 |
Ultrasound-guided Percutaneous Cryoneurolysis to Treat Chronic Postamputation Phantom Limb Pain: A Multicenter Randomized Controlled Trial.
Topics: Cold Temperature; Humans; Lidocaine; Nerve Block; Phantom Limb; Ultrasonography, Interventional | 2023 |
Ultrasound-guided Percutaneous Cryoneurolysis to Treat Chronic Postamputation Phantom Limb Pain: A Multicenter Randomized Controlled Trial.
Topics: Cold Temperature; Humans; Lidocaine; Nerve Block; Phantom Limb; Ultrasonography, Interventional | 2023 |
Ultrasound-guided Percutaneous Cryoneurolysis to Treat Chronic Postamputation Phantom Limb Pain: A Multicenter Randomized Controlled Trial.
Topics: Cold Temperature; Humans; Lidocaine; Nerve Block; Phantom Limb; Ultrasonography, Interventional | 2023 |
The role of afferent input in postamputation pain: a randomized, double-blind, placebo-controlled crossover study.
Topics: Adult; Aged; Amputation Stumps; Amputation, Surgical; Amputees; Anesthetics, Local; Cross-Over Studi | 2019 |
Heightened motor and sensory (mirror-touch) referral induced by nerve block or topical anesthetic.
Topics: Administration, Topical; Adult; Aged; Anesthetics, Local; Double-Blind Method; Female; Functional La | 2013 |
A prospective randomized double-blinded pilot study to examine the effect of botulinum toxin type A injection versus Lidocaine/Depomedrol injection on residual and phantom limb pain: initial report.
Topics: Adult; Aged; Amputation Stumps; Analgesics; Botulinum Toxins, Type A; Double-Blind Method; Female; H | 2012 |
Regulation of proprioceptive memory by subarachnoid regional anesthesia.
Topics: Adult; Aged; Aged, 80 and over; Anesthesia, Conduction; Anesthetics, Local; Bupivacaine; Female; Hum | 2000 |
Analgesic effects of intravenous lidocaine and morphine on postamputation pain: a randomized double-blind, active placebo-controlled, crossover trial.
Topics: Adult; Aged; Amputation Stumps; Amputation, Surgical; Cross-Over Studies; Double-Blind Method; Femal | 2002 |
Pain responses to perineuromal injection of normal saline, gallamine, and lidocaine in humans.
Topics: Adult; Aged; Gallamine Triethiodide; Humans; Lidocaine; Middle Aged; Neuroma; Pain; Pain Measurement | 1989 |
10 other studies available for lidocaine and Phantom Limb
| Article | Year |
|---|---|
Peripheral nervous system origin of phantom limb pain.
Topics: Adult; Aged; Anesthesia, Spinal; Anesthetics, Local; Female; Ganglia, Spinal; Humans; Injections, Sp | 2014 |
Myoclonus of peripheral origin: two case reports.
Topics: Adolescent; Amputation Stumps; Anterior Horn Cells; Anti-Dyskinesia Agents; Arm Injuries; Botulinum | 2009 |
Motor commands contribute to human position sense.
Topics: Efferent Pathways; Humans; Ischemia; Kinesthesis; Lidocaine; Motor Neurons; Muscle, Skeletal; Nerve | 2006 |
Reactivation of phantom limb pain after combined interscalene brachial plexus block and general anesthesia: successful treatment with intravenous lidocaine.
Topics: Anesthesia, General; Brachial Plexus; Bupivacaine; Female; Humans; Injections, Intravenous; Isoflura | 1995 |
Lignocaine for acute phantom limb pain reactivation by regional anaesthesia.
Topics: Anesthesia, Conduction; Anesthetics, Local; Humans; Injections, Intravenous; Lidocaine; Pain; Phanto | 1996 |
Potentiation of sensory responses in the anterior cingulate cortex following digit amputation in the anaesthetised rat.
Topics: Amputation, Surgical; Anesthesia; Anesthetics, Local; Animals; Electroshock; Excitatory Postsynaptic | 2001 |
Phanton limb sensation under subarachnoid and epidural analgesia - a comparative clinical study of two hundred cases.
Topics: Adult; Anesthesia, Epidural; Anesthesia, Spinal; Female; Humans; Lidocaine; Male; Middle Aged; Phant | 1979 |
A comparison of the effects of intrathecal fentanyl and lidocaine on established postamputation stump pain.
Topics: Adult; Aged; Amputation Stumps; Fentanyl; Humans; Injections, Spinal; Lidocaine; Male; Middle Aged; | 1990 |
Relief of persistent postamputation stump and phantom limb pain with intrathecal fentanyl.
Topics: Adult; Fentanyl; Humans; Injections, Spinal; Lidocaine; Male; Middle Aged; Pain, Postoperative; Phan | 1989 |
The contribution of muscle afferents to kinaesthesia shown by vibration induced illusions of movement and by the effects of paralysing joint afferents.
Topics: Elbow; Humans; Hypoxia; Illusions; Joints; Kinesthesis; Lidocaine; Movement; Muscle Contraction; Mus | 1972 |