lidocaine has been researched along with Peripheral Nervous System Diseases in 75 studies
Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.
Peripheral Nervous System Diseases: Diseases of the peripheral nerves external to the brain and spinal cord, which includes diseases of the nerve roots, ganglia, plexi, autonomic nerves, sensory nerves, and motor nerves.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Oral amitriptyline, a tricyclic antidepressant, is effective for treating neuropathic pain." | 9.13 | Topical amitriptyline versus lidocaine in the treatment of neuropathic pain. ( Ho, KY; Huh, BK; Miller, EJ; White, WD; Yeh, CC, 2008) |
| "Ketamine significantly reduced ongoing pain and evoked pain to brush and pinprick, whereas lidocaine only reduced evoked pain to repetitive pinprick stimuli." | 9.12 | Differential effect of ketamine and lidocaine on spontaneous and mechanical evoked pain in patients with nerve injury pain. ( Bach, FW; Gottrup, H; Jensen, TS; Juhl, G, 2006) |
| "As an adjuvant medication, the lidocaine patch is effective and safe for reducing chronic pain and physical complaints in focal non-herpetic neuropathies." | 9.11 | [Reduction of chronic pain for non-postherpetic peripheral neuropathies after topical treatment with a lidocaine patch]. ( Faust, M; Hüppe, M; Meier, T; Schmucker, P, 2004) |
| "Our goal was to perform a pilot study to assess the effectiveness and tolerability of a topical lidocaine patch (Lidoderm) for the treatment of peripheral neuropathic pain conditions other than postherpetic neuralgia." | 9.09 | Topical lidocaine patch relieves a variety of neuropathic pain conditions: an open-label study. ( Devers, A; Galer, BS, 2000) |
| "Lidocaine is a use-dependent sodium channel blocker that produces analgesia when administered intravenously to patients with neuropathic pain." | 8.84 | Intravenous lidocaine for neuropathic pain: diagnostic utility and therapeutic efficacy. ( Carroll, I, 2007) |
| "The purpose of this study was to describe the therapeutic effectiveness/pain relief of moderate-dose lidocaine infusions in patients with chronic neuropathic pain." | 7.91 | Intravenous Lidocaine for Relief of Chronic Neuropathic Pain. ( Albala, MZ; Hudson, A; Lancaster, RJ; Leavitt, K; Margelosky, K; Walesh, M; Wren, K, 2019) |
| "The proportion of chronic pain patients with suspected neuropathic pain who will have clinically meaningful pain relief with intravenous (IV) lidocaine and the clinical characteristics that identify these patients have not been described previously." | 7.74 | Multivariate analysis of chronic pain patients undergoing lidocaine infusions: increasing pain severity and advancing age predict likelihood of clinically meaningful analgesia. ( Carroll, I; Gaeta, R; Mackey, S, 2007) |
| "Lidocaine is effective in controlling ventricular dysrhythmia and neuropathic pain." | 7.72 | Amiodarone decreases heat, cold, and mechanical hyperalgesia in a rat model of neuropathic pain. ( Datta, S; Glusman, S; Torres, M; Waghray, T, 2004) |
| "Eighty-five patients (90%), responders to lidocaine, had a pain relief and 71 patients (85%), no responders to lidocaine, did not have improvement by taking oral drugs." | 7.70 | [The predictive lidocaine test in treatment of neuropathic pain]. ( Trentin, L; Visentin, M, 2000) |
| " The VAS-pain and VAS-pruritus scores were significantly decreased at all follow-up sessions, and improvement was sustained by lidocaine up to the third month." | 5.34 | Notalgia paresthetica: clinical features, radiological evaluation, and a novel therapeutic option. ( Mülkoğlu, C; Nacır, B, 2020) |
| "A topical lidocaine patch is effective in the treatment of posttraumatic peripheral neuropathy (PTPN), but it is not suited for breakthrough pain because of difficulty with an additional application." | 5.14 | The analgesic effect of a metered-dose 8% lidocaine pump spray in posttraumatic peripheral neuropathy: a pilot study. ( Kanai, A; Koto, M; Okamoto, H; Okamoto, T; Segawa, Y, 2009) |
| " In this study, we evaluated the AMPA/GluR5 receptor antagonist NS1209 for efficacy, safety, and tolerability in comparison with placebo and lidocaine for the treatment of chronic neuropathic pain and allodynia in patients with peripheral nerve injury." | 5.14 | The efficacy of the AMPA receptor antagonist NS1209 and lidocaine in nerve injury pain: a randomized, double-blind, placebo-controlled, three-way crossover study. ( Almqvist, PM; Finnerup, NB; Gormsen, L; Jensen, TS, 2009) |
| "Oral amitriptyline, a tricyclic antidepressant, is effective for treating neuropathic pain." | 5.13 | Topical amitriptyline versus lidocaine in the treatment of neuropathic pain. ( Ho, KY; Huh, BK; Miller, EJ; White, WD; Yeh, CC, 2008) |
| "Ketamine significantly reduced ongoing pain and evoked pain to brush and pinprick, whereas lidocaine only reduced evoked pain to repetitive pinprick stimuli." | 5.12 | Differential effect of ketamine and lidocaine on spontaneous and mechanical evoked pain in patients with nerve injury pain. ( Bach, FW; Gottrup, H; Jensen, TS; Juhl, G, 2006) |
| "As an adjuvant medication, the lidocaine patch is effective and safe for reducing chronic pain and physical complaints in focal non-herpetic neuropathies." | 5.11 | [Reduction of chronic pain for non-postherpetic peripheral neuropathies after topical treatment with a lidocaine patch]. ( Faust, M; Hüppe, M; Meier, T; Schmucker, P, 2004) |
| "Our goal was to perform a pilot study to assess the effectiveness and tolerability of a topical lidocaine patch (Lidoderm) for the treatment of peripheral neuropathic pain conditions other than postherpetic neuralgia." | 5.09 | Topical lidocaine patch relieves a variety of neuropathic pain conditions: an open-label study. ( Devers, A; Galer, BS, 2000) |
| " This painful condition, occurring during the immediate postoperative period, is termed transient neurological symptoms (TNS) and is typically observed after the use of spinal lidocaine." | 5.01 | Transient neurological symptoms (TNS) following spinal anaesthesia with lidocaine versus other local anaesthetics in adult surgical patients: a network meta-analysis. ( Borovac, JA; Forget, P; Pace, NL; Thackeray, EM, 2019) |
| "Lidocaine is a use-dependent sodium channel blocker that produces analgesia when administered intravenously to patients with neuropathic pain." | 4.84 | Intravenous lidocaine for neuropathic pain: diagnostic utility and therapeutic efficacy. ( Carroll, I, 2007) |
| "The purpose of this study was to describe the therapeutic effectiveness/pain relief of moderate-dose lidocaine infusions in patients with chronic neuropathic pain." | 3.91 | Intravenous Lidocaine for Relief of Chronic Neuropathic Pain. ( Albala, MZ; Hudson, A; Lancaster, RJ; Leavitt, K; Margelosky, K; Walesh, M; Wren, K, 2019) |
| " We report a case in which a patient presenting with chemotherapy-induced peripheral neuropathy received an IV lidocaine infusion over the course of 60 minutes with complete symptomatic pain relief for a prolonged period of 2 weeks." | 3.81 | Intravenous Lidocaine Infusion to Treat Chemotherapy-Induced Peripheral Neuropathy. ( Chakrabortty, S; Kumar, AJ; Muppuri, R; Papapetrou, P, 2015) |
| "The proportion of chronic pain patients with suspected neuropathic pain who will have clinically meaningful pain relief with intravenous (IV) lidocaine and the clinical characteristics that identify these patients have not been described previously." | 3.74 | Multivariate analysis of chronic pain patients undergoing lidocaine infusions: increasing pain severity and advancing age predict likelihood of clinically meaningful analgesia. ( Carroll, I; Gaeta, R; Mackey, S, 2007) |
| "Systemic lidocaine and other local anesthetics reduce hypersensitivity states induced by both acute inflammation and peripheral nerve injury in animals and produce analgesia in some patients with chronic pain." | 3.72 | Intrathecal lidocaine reverses tactile allodynia caused by nerve injuries and potentiates the antiallodynic effect of the COX inhibitor ketorolac. ( Du, W; Eisenach, JC; Ma, W, 2003) |
| "Lidocaine is effective in controlling ventricular dysrhythmia and neuropathic pain." | 3.72 | Amiodarone decreases heat, cold, and mechanical hyperalgesia in a rat model of neuropathic pain. ( Datta, S; Glusman, S; Torres, M; Waghray, T, 2004) |
| "Eighty-five patients (90%), responders to lidocaine, had a pain relief and 71 patients (85%), no responders to lidocaine, did not have improvement by taking oral drugs." | 3.70 | [The predictive lidocaine test in treatment of neuropathic pain]. ( Trentin, L; Visentin, M, 2000) |
| "Lidocaine may be useful in the treatment of neuropathic pain states." | 3.69 | Prolonged alleviation of tactile allodynia by intravenous lidocaine in neuropathic rats. ( Bach, FW; Chaplan, SR; Shafer, SL; Yaksh, TL, 1995) |
| "Prilocaine results in a lower incidence of transient neurological symptoms than lidocaine intrathecally and therefore it is more suitable for short surgical procedures." | 2.69 | The incidence of transient neurological symptoms after spinal anaesthesia with lidocaine compared to prilocaine. ( de Weert, K; Dirksen, R; Gielen, M; Slappendel, R; Traksel, M; Weber, E, 2000) |
| "Fourteen patients with neuropathic pain (7 with unilateral foot pain due to peripheral nerve injury and 7 with bilateral pain in the feet due to distal polyneuropathy) underwent comprehensive characterization of somatosensory function by quantitative sensory testing." | 1.40 | Primary afferent input critical for maintaining spontaneous pain in peripheral neuropathy. ( Bendtsen, TF; Finnerup, NB; Haroutounian, S; Hasselstrøm, JB; Jensen, TS; Kristensen, AD; Nikolajsen, L, 2014) |
| "Lidocaine was either applied to the nerve at or distal to the injury site in concentrations of 1 to 1000 μg/mL or injected i." | 1.37 | Effect of local and intravenous lidocaine on ongoing activity in injured afferent nerve fibers. ( Baron, R; Bartsch, F; Gorodetskaya, N; Grossmann, L; Jänig, W; Kirillova, I; Rausch, VH; Struck, M; Teliban, A; Tode, J, 2011) |
| "The term "peripheral neuropathic pain syndromes" summarizes several chronic pain syndromes, which can occur focally or generalized in the peripheral nervous system in the course of an impairment of afferent neurons." | 1.36 | [Types of topical treatment for peripheral neuropathic pain : Mechanism of action and indications]. ( Baron, R; Mahn, F, 2010) |
| "The effect of lidocaine pretreatment on thermal hyperalgesia and thermal skin asymmetries provoked by experimental mononeuropathy was investigated in rats." | 1.29 | Pre-injury lidocaine treatment prevents thermal hyperalgesia and cutaneous thermal abnormalities in a rat model of peripheral neuropathy. ( Castagna, A; Lacerenza, M; Marchettini, P; Sotgiu, ML, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (16.00) | 18.7374 |
| 1990's | 19 (25.33) | 18.2507 |
| 2000's | 29 (38.67) | 29.6817 |
| 2010's | 13 (17.33) | 24.3611 |
| 2020's | 2 (2.67) | 2.80 |
| Authors | Studies |
|---|---|
| Correa-Illanes, G | 1 |
| Wren, K | 1 |
| Lancaster, RJ | 1 |
| Walesh, M | 1 |
| Margelosky, K | 1 |
| Leavitt, K | 1 |
| Hudson, A | 1 |
| Albala, MZ | 1 |
| Forget, P | 1 |
| Borovac, JA | 1 |
| Thackeray, EM | 1 |
| Pace, NL | 3 |
| Mülkoğlu, C | 1 |
| Nacır, B | 1 |
| Mohammed, AK | 1 |
| Lalonde, DH | 1 |
| Moulin, DE | 1 |
| Morley-Forster, PK | 1 |
| Pirani, Z | 1 |
| Rohfritsch, C | 1 |
| Stitt, L | 1 |
| Kochhar, JS | 1 |
| Lim, WX | 1 |
| Zou, S | 1 |
| Foo, WY | 1 |
| Pan, J | 1 |
| Kang, L | 1 |
| Kodaira, M | 1 |
| Inui, K | 2 |
| Kakigi, R | 2 |
| Haroutounian, S | 1 |
| Nikolajsen, L | 1 |
| Bendtsen, TF | 1 |
| Finnerup, NB | 2 |
| Kristensen, AD | 1 |
| Hasselstrøm, JB | 1 |
| Jensen, TS | 3 |
| Papapetrou, P | 1 |
| Kumar, AJ | 1 |
| Muppuri, R | 1 |
| Chakrabortty, S | 1 |
| Kanai, A | 1 |
| Segawa, Y | 1 |
| Okamoto, T | 1 |
| Koto, M | 1 |
| Okamoto, H | 1 |
| Gormsen, L | 1 |
| Almqvist, PM | 1 |
| Umbrain, V | 1 |
| Smolders, I | 1 |
| Poelaert, J | 1 |
| Zaric, D | 2 |
| Viisanen, H | 1 |
| Pertovaara, A | 2 |
| Otsuru, N | 1 |
| Yamashiro, K | 1 |
| Miyazaki, T | 1 |
| Takeshima, Y | 1 |
| Baron, R | 3 |
| Mahn, F | 1 |
| Kirillova, I | 1 |
| Teliban, A | 1 |
| Gorodetskaya, N | 1 |
| Grossmann, L | 1 |
| Bartsch, F | 1 |
| Rausch, VH | 1 |
| Struck, M | 1 |
| Tode, J | 1 |
| Jänig, W | 1 |
| Berger, A | 1 |
| Sadosky, A | 1 |
| Dukes, E | 1 |
| Edelsberg, J | 1 |
| Oster, G | 1 |
| Kauppila, T | 1 |
| Kontinen, VK | 1 |
| Wei, H | 1 |
| Jyväsjärvi, E | 1 |
| Sandroni, P | 1 |
| Jost, U | 1 |
| Ma, W | 1 |
| Du, W | 1 |
| Eisenach, JC | 1 |
| SCHNEEWIND, JH | 1 |
| MARWAH, V | 1 |
| Meier, T | 2 |
| Wasner, G | 1 |
| Faust, M | 2 |
| Kuntzer, T | 1 |
| Ochsner, F | 1 |
| Hueppe, M | 1 |
| Bogousslavsky, J | 1 |
| Datta, S | 1 |
| Waghray, T | 1 |
| Torres, M | 1 |
| Glusman, S | 1 |
| Hüppe, M | 1 |
| Schmucker, P | 1 |
| Neafsey, PJ | 1 |
| Cohen, SP | 1 |
| Chang, AS | 1 |
| Larkin, T | 1 |
| Mao, J | 1 |
| Wilhelm, IR | 1 |
| Griessinger, N | 1 |
| Koppert, W | 1 |
| Sittl, R | 1 |
| Likar, R | 1 |
| Saadé, NE | 1 |
| Al Amin, H | 1 |
| Abdel Baki, S | 1 |
| Safieh-Garabedian, B | 1 |
| Atweh, SF | 1 |
| Jabbur, SJ | 1 |
| Christiansen, C | 1 |
| Punjasawadwong, Y | 1 |
| Tremont-Lukats, IW | 1 |
| Challapalli, V | 1 |
| McNicol, ED | 1 |
| Lau, J | 1 |
| Carr, DB | 1 |
| Gottrup, H | 1 |
| Bach, FW | 2 |
| Juhl, G | 1 |
| Malmstrom, K | 1 |
| Kotey, P | 1 |
| McGratty, M | 1 |
| Ramakrishnan, R | 1 |
| Gottesdiener, K | 1 |
| Reicin, A | 1 |
| Wagner, JA | 1 |
| Carroll, I | 2 |
| ter Meulen, BC | 1 |
| Peters, EW | 1 |
| Wijsmuller, A | 1 |
| Kropman, RF | 1 |
| Mosch, A | 1 |
| Tavy, DL | 1 |
| Gaeta, R | 1 |
| Mackey, S | 1 |
| Ho, KY | 1 |
| Huh, BK | 1 |
| White, WD | 1 |
| Yeh, CC | 1 |
| Miller, EJ | 1 |
| Gu, YW | 1 |
| Su, DS | 1 |
| Tian, J | 1 |
| Wang, XR | 1 |
| Carpenter, RL | 1 |
| Hampl, KF | 3 |
| Schneider, MC | 3 |
| Ummenhofer, W | 1 |
| Drewe, J | 2 |
| Strichartz, G | 1 |
| Chaplan, SR | 1 |
| Shafer, SL | 1 |
| Yaksh, TL | 1 |
| Sotgiu, ML | 1 |
| Castagna, A | 1 |
| Lacerenza, M | 1 |
| Marchettini, P | 1 |
| Douglas, MJ | 1 |
| Thompson, GE | 1 |
| Chow, JM | 1 |
| Bainton, CR | 1 |
| Strichartz, GR | 1 |
| Cameron, J | 1 |
| Flowers, AE | 1 |
| Capra, MF | 1 |
| Zapp, JJ | 1 |
| Short, S | 1 |
| Bont, A | 1 |
| Pargger, H | 2 |
| Kurvers, HA | 1 |
| Tangelder, GJ | 1 |
| De Mey, JG | 1 |
| Slaaf, DW | 1 |
| van den Wildenberg, FA | 1 |
| Kitslaar, PJ | 1 |
| Reneman, RS | 1 |
| Rouwet, EV | 1 |
| Jacobs, MJ | 1 |
| Gut, J | 1 |
| Drasner, K | 1 |
| König, W | 1 |
| Ruzicic, D | 1 |
| Gielen, M | 2 |
| Dorfman, D | 1 |
| Dalton, A | 1 |
| Khan, A | 1 |
| Markarian, Y | 1 |
| Scarano, A | 1 |
| Cansino, M | 1 |
| Wulff, E | 1 |
| Simpson, D | 1 |
| Pollock, JE | 1 |
| Burkhead, D | 1 |
| Neal, JM | 1 |
| Liu, SS | 1 |
| Friedman, A | 1 |
| Stephenson, C | 1 |
| Polissar, NL | 1 |
| Trentin, L | 1 |
| Visentin, M | 1 |
| Horiuchi, J | 1 |
| Sato, Y | 1 |
| de Weert, K | 1 |
| Traksel, M | 1 |
| Slappendel, R | 1 |
| Weber, E | 1 |
| Dirksen, R | 1 |
| Devers, A | 1 |
| Galer, BS | 1 |
| Bergman, MA | 1 |
| Hahn, AF | 1 |
| Parkes, AW | 1 |
| Bolton, CF | 1 |
| Stewart, SA | 1 |
| De Vera, HV | 1 |
| Nyström, A | 1 |
| Lindström, G | 1 |
| Reiz, S | 1 |
| Hanel, DP | 1 |
| Escobar, PL | 1 |
| Ballesteros, J | 1 |
| Rowlingson, JC | 1 |
| Kirschenbaum, LP | 1 |
| Crews, DA | 1 |
| Dohlman, LE | 1 |
| Swan, HJ | 1 |
| Phillips, OC | 1 |
| Ebner, H | 1 |
| Nelson, AT | 1 |
| Black, MH | 1 |
| Applegate, WV | 1 |
| Teng, P | 1 |
| Black, JT | 1 |
| Garcia-Mullin, R | 1 |
| Good, E | 1 |
| Brown, S | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Role of Intravenous (IV) Lidocaine in the Management of Chronic Neuropathic Pain of Peripheral Nerve Origin[NCT01669967] | 34 participants (Actual) | Interventional | 2011-09-30 | Completed | |||
| Diode Laser as a Biomarker for Neuropathic Pain of Peripheral Origin.[NCT06030297] | 301 participants (Anticipated) | Interventional | 2022-11-01 | Recruiting | |||
| The Significance of Peripheral Input in Patients With Post Surgery Neuropathic Pain: Evaluation of Trigger Point Anesthesia. A Double-blind, Randomized, Controlled Exploratory Study[NCT04764045] | 12 participants (Anticipated) | Interventional | 2019-11-20 | Recruiting | |||
| Cognitive Changes Associated With Initiation of Gabapentin Treatment in Adults With Chronic Pain[NCT04106011] | 3 participants (Actual) | Observational | 2020-01-10 | Terminated (stopped due to PI request - low enrollment) | |||
| High Dose Intravenous Lidocaine vs Hydromorphone for Acute Abdominal Pain in the Emergency Department: A Randomized, Comparative Efficacy Trial[NCT04398316] | Phase 4 | 187 participants (Anticipated) | Interventional | 2021-02-18 | Recruiting | ||
| Lidocaine With Epinephrine vs. Bupivacaine With Epinephrine as Local Anesthetic Agents in Wide-awake Hand Surgery: an Outcome Study of Patients' Pain Perception.[NCT02315573] | 61 participants (Actual) | Interventional | 2014-10-31 | Completed | |||
| Do Cervical Interlaminar Epidural Steroid Injections With Low-dose Lidocaine Cause Transient Objective Upper Extremity Weakness? A Prospective Randomized Controlled Trial[NCT03127137] | Phase 4 | 123 participants (Actual) | Interventional | 2018-08-01 | Completed | ||
| Do Cervical Interlaminar Epidural Steroid Injections With Low-dose Lidocaine Cause Transient Objective Upper Extremity Weakness? A Prospective Randomized[NCT03382925] | Phase 4 | 16 participants (Actual) | Interventional | 2017-12-20 | Terminated (stopped due to Not enough cervical interlaminar patients who meet criteria in order to meet recruitment goals.) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Change in strength in both groups greater than or equal to 20% weakness in one or more myotomes 30 minutes after CESI using a hand held Dynamometer. (NCT03127137)
Timeframe: 30 minutes after the CESI procedure
| Intervention | Participants (Count of Participants) | |
|---|---|---|
| Yes, greater or equal to 20% weakness in greater or equal to 1 or more myotome | No, greater or equal to 20% weakness in greater or equal to 1 or more myotome | |
| Experimental Group 1 With Lidocaine | 25 | 35 |
| Experimental Group 2 With Saline | 30 | 30 |
7 reviews available for lidocaine and Peripheral Nervous System Diseases
| Article | Year |
|---|---|
Transient neurological symptoms (TNS) following spinal anaesthesia with lidocaine versus other local anaesthetics in adult surgical patients: a network meta-analysis.
Topics: Anesthesia, Local; Anesthesia, Spinal; Anesthetics, Local; Humans; Lidocaine; Network Meta-Analysis; | 2019 |
Transient neurologic symptoms (TNS) following spinal anaesthesia with lidocaine versus other local anaesthetics.
Topics: Anesthesia, Spinal; Anesthetics, Local; Humans; Leg; Lidocaine; Pain; Peripheral Nervous System Dise | 2009 |
Patching pain with lidocaine: new uses for the lidocaine 5% patch.
Topics: Administration, Cutaneous; Anesthetics, Local; Back Pain; Humans; Lidocaine; Neuralgia; Osteoarthrit | 2004 |
Transient neurologic symptoms (TNS) following spinal anaesthesia with lidocaine versus other local anaesthetics.
Topics: Anesthesia, Spinal; Anesthetics, Local; Humans; Leg; Lidocaine; Pain; Peripheral Nervous System Dise | 2005 |
Systemic administration of local anesthetics to relieve neuropathic pain: a systematic review and meta-analysis.
Topics: Anesthetics, Local; Humans; Lidocaine; Mexiletine; Pain; Peripheral Nervous System Diseases; Randomi | 2005 |
Intravenous lidocaine for neuropathic pain: diagnostic utility and therapeutic efficacy.
Topics: Anesthetics, Local; Humans; Infusions, Intravenous; Lidocaine; Mexiletine; Pain; Peripheral Nervous | 2007 |
Spinal anaesthesia: hearing loss, failure, transient radicular irritation (TRI).
Topics: Anesthesia, Spinal; Anesthetics, Local; Hearing Disorders; Humans; Lidocaine; Peripheral Nervous Sys | 1998 |
15 trials available for lidocaine and Peripheral Nervous System Diseases
| Article | Year |
|---|---|
Notalgia paresthetica: clinical features, radiological evaluation, and a novel therapeutic option.
Topics: Adult; Aged; Anesthetics, Local; Cross-Sectional Studies; Female; Humans; Hyperpigmentation; Interve | 2020 |
Intravenous lidocaine in the management of chronic peripheral neuropathic pain: a randomized-controlled trial.
Topics: Aged; Anesthetics, Local; Chronic Pain; Cross-Over Studies; Diabetic Neuropathies; Diphenhydramine; | 2019 |
The analgesic effect of a metered-dose 8% lidocaine pump spray in posttraumatic peripheral neuropathy: a pilot study.
Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Local; Double-Blind Method; Female; Humans; Lidocaine; | 2009 |
The efficacy of the AMPA receptor antagonist NS1209 and lidocaine in nerve injury pain: a randomized, double-blind, placebo-controlled, three-way crossover study.
Topics: Adult; Aged; Analgesia; Anesthetics, Local; Chronic Disease; Cross-Over Studies; Double-Blind Method | 2009 |
Efficacy of lidocaine patch 5% in the treatment of focal peripheral neuropathic pain syndromes: a randomized, double-blind, placebo-controlled study.
Topics: Administration, Topical; Aged; Anesthetics, Local; Cross-Over Studies; Double-Blind Method; Female; | 2003 |
[Reduction of chronic pain for non-postherpetic peripheral neuropathies after topical treatment with a lidocaine patch].
Topics: Administration, Topical; Aged; Aged, 80 and over; Anesthetics, Local; Double-Blind Method; Female; H | 2004 |
The intravenous ketamine test: a predictive response tool for oral dextromethorphan treatment in neuropathic pain.
Topics: Administration, Oral; Adult; Anesthetics, Local; Databases, Factual; Dextromethorphan; Excitatory Am | 2004 |
Differential effect of ketamine and lidocaine on spontaneous and mechanical evoked pain in patients with nerve injury pain.
Topics: Adult; Aged; Cross-Over Studies; Double-Blind Method; Female; Humans; Ketamine; Lidocaine; Male; Mid | 2006 |
Dental impaction pain model as a potential tool to evaluate drugs with efficacy in neuropathic pain.
Topics: Acetaminophen; Adolescent; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthetics, Local; | 2006 |
Topical amitriptyline versus lidocaine in the treatment of neuropathic pain.
Topics: Administration, Topical; Amitriptyline; Analgesics, Non-Narcotic; Anesthetics, Local; Double-Blind M | 2008 |
Transient neurologic symptoms after spinal anesthesia.
Topics: Adolescent; Adult; Aged; Anesthesia, Obstetrical; Anesthesia, Spinal; Anesthetics, Local; Bupivacain | 1995 |
A similar incidence of transient neurologic symptoms after spinal anesthesia with 2% and 5% lidocaine.
Topics: Adult; Anesthesia, Spinal; Anesthetics, Local; Female; Genitalia, Female; Humans; Incidence; Lidocai | 1996 |
The incidence of transient neurological symptoms after spinal anaesthesia with lidocaine compared to prilocaine.
Topics: Adolescent; Adult; Aged; Anesthesia, Spinal; Anesthetics, Local; Double-Blind Method; Female; Humans | 2000 |
Topical lidocaine patch relieves a variety of neuropathic pain conditions: an open-label study.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Anesthetics, Local; Female; Humans; Lidocai | 2000 |
Bupivacaine: a safe local anesthetic for wrist blocks.
Topics: Bupivacaine; Double-Blind Method; Hand; Humans; Lidocaine; Nerve Block; Peripheral Nervous System Di | 1989 |
53 other studies available for lidocaine and Peripheral Nervous System Diseases
| Article | Year |
|---|---|
Successful treatment of notalgia paresthetica with lidocaine 5% medicated plaster: a case report.
Topics: Aged; Female; Humans; Lidocaine; Pain; Paresthesia; Peripheral Nervous System Diseases; Pruritus | 2022 |
Intravenous Lidocaine for Relief of Chronic Neuropathic Pain.
Topics: Anesthetics, Local; Female; Humans; Infusions, Intravenous; Lidocaine; Male; Middle Aged; Nurse Anes | 2019 |
Wide Awake Tendon Transfers in Leprosy Patients in India.
Topics: Adolescent; Adult; Ambulatory Surgical Procedures; Anesthesia, Local; Anesthetics, Local; Epinephrin | 2019 |
Microneedle integrated transdermal patch for fast onset and sustained delivery of lidocaine.
Topics: Administration, Cutaneous; Adult; Animals; Female; Humans; Lidocaine; Male; Peripheral Nervous Syste | 2013 |
Evaluation of nociceptive Aδ- and C-fiber dysfunction with lidocaine using intraepidermal electrical stimulation.
Topics: Adult; Anesthetics, Local; Electric Stimulation; Evoked Potentials; Female; Humans; Injections, Intr | 2014 |
Primary afferent input critical for maintaining spontaneous pain in peripheral neuropathy.
Topics: Adolescent; Adult; Afferent Pathways; Aged; Aged, 80 and over; Anesthetics, Local; Central Nervous S | 2014 |
Primary afferent input critical for maintaining spontaneous pain in peripheral neuropathy.
Topics: Adolescent; Adult; Afferent Pathways; Aged; Aged, 80 and over; Anesthetics, Local; Central Nervous S | 2014 |
Primary afferent input critical for maintaining spontaneous pain in peripheral neuropathy.
Topics: Adolescent; Adult; Afferent Pathways; Aged; Aged, 80 and over; Anesthetics, Local; Central Nervous S | 2014 |
Primary afferent input critical for maintaining spontaneous pain in peripheral neuropathy.
Topics: Adolescent; Adult; Afferent Pathways; Aged; Aged, 80 and over; Anesthetics, Local; Central Nervous S | 2014 |
Intravenous Lidocaine Infusion to Treat Chemotherapy-Induced Peripheral Neuropathy.
Topics: Antineoplastic Agents; Breast Neoplasms; Female; Humans; Hypesthesia; Infusions, Intravenous; Lidoca | 2015 |
Is Intrathecal lidocaine administration risk-free in rats with neuropathic pain? Reply to [Effects of intrathecal lidocaine on hyperalgesia and allodynia following chronic constriction injury in rats. Eur J Pain 13 (2009) 130-137].
Topics: Anesthetics, Local; Animals; Constriction, Pathologic; Cytokines; Dinoprostone; Hyperalgesia; Inject | 2009 |
Antinociception by motor cortex stimulation in the neuropathic rat: does the locus coeruleus play a role?
Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Anesthetics, Local; Animals; | 2010 |
Assessing Aδ fiber function with lidocaine using intraepidermal electrical stimulation.
Topics: Adult; Anesthetics, Local; Electric Stimulation; Electrodes; Electrodiagnosis; Epidermis; Female; Hu | 2010 |
[Types of topical treatment for peripheral neuropathic pain : Mechanism of action and indications].
Topics: Administration, Topical; Afferent Pathways; Analgesics; Anesthetics, Local; Antidepressive Agents; C | 2010 |
Effect of local and intravenous lidocaine on ongoing activity in injured afferent nerve fibers.
Topics: Action Potentials; Anesthetics, Local; Animals; Blood Pressure; Disease Models, Animal; Drug Adminis | 2011 |
Clinical characteristics and patterns of healthcare utilization in patients with painful neuropathic disorders in UK general practice: a retrospective cohort study.
Topics: Adult; Aged; Analgesics; Analgesics, Opioid; Anesthetics, Local; Anti-Inflammatory Agents, Non-Stero | 2012 |
Cutaneous vascular responses evoked by noxious stimulation in rats with the spinal nerve ligation-induced model of neuropathy.
Topics: Anesthetics, Local; Animals; Axons; Coloring Agents; Electric Stimulation; Evans Blue; Laser-Doppler | 2002 |
Central neuropathic itch: a new treatment option?
Topics: Administration, Cutaneous; Anesthetics, Local; Female; Humans; Lidocaine; Middle Aged; Peripheral Ne | 2002 |
[Spinal anesthesia: articaine, prilocaine, lidocaine?].
Topics: Anesthesia, Spinal; Anesthetics, Local; Carticaine; Humans; Lidocaine; Peripheral Nervous System Dis | 2002 |
Intrathecal lidocaine reverses tactile allodynia caused by nerve injuries and potentiates the antiallodynic effect of the COX inhibitor ketorolac.
Topics: Anesthetics, Local; Animals; Behavior, Animal; Cyclooxygenase Inhibitors; Dose-Response Relationship | 2003 |
ANCILLARY PROCEDURES IN HAND SURGERY.
Topics: Autonomic Nerve Block; Bandages; Hand; Hand Injuries; Humans; Lidocaine; Occupational Therapy; Perip | 1964 |
COMPRESSION OF THE LATERAL POPLITEAL (COMMON PERONEAL) NERVE.
Topics: Female; Humans; Lactation; Lidocaine; Neurosurgery; Peripheral Nervous System Diseases; Peroneal Ner | 1964 |
Amiodarone decreases heat, cold, and mechanical hyperalgesia in a rat model of neuropathic pain.
Topics: Amiodarone; Anesthetics, Local; Animals; Cold Temperature; Hot Temperature; Hyperalgesia; Injections | 2004 |
High doses of topically applied lidocaine in a cancer patient.
Topics: Administration, Topical; Anesthetics, Local; Bone Neoplasms; Humans; Lidocaine; Osteosarcoma; Pain; | 2005 |
Transient attenuation of neuropathic manifestations in rats following lesion or reversible block of the lateral thalamic somatosensory nuclei.
Topics: Anesthetics, Local; Animals; Behavior, Animal; Cold Temperature; Excitatory Amino Acid Agonists; Fem | 2006 |
Acute scrotal pain from idiopathic ilioinguinal neuropathy: diagnosis and treatment with EMG-guided nerve block.
Topics: Adult; Electrodes, Implanted; Electromyography; Genital Diseases, Male; Humans; Inguinal Canal; Inje | 2007 |
Multivariate analysis of chronic pain patients undergoing lidocaine infusions: increasing pain severity and advancing age predict likelihood of clinically meaningful analgesia.
Topics: Adolescent; Adult; Aged; Aging; Analysis of Variance; Anesthetics, Local; Chronic Disease; Cohort St | 2007 |
Attenuating phosphorylation of p38 MAPK in the activated microglia: a new mechanism for intrathecal lidocaine reversing tactile allodynia following chronic constriction injury in rats.
Topics: Anesthetics, Local; Animals; Constriction, Pathologic; Disease Models, Animal; Hyperesthesia; Inject | 2008 |
Hyperbaric lidocaine spinal anesthesia: do we need an alternative?
Topics: Anesthesia, Spinal; Anesthetics, Local; Bupivacaine; Drug Monitoring; Humans; Lidocaine; Pain; Perip | 1995 |
Protracted relief of experimental neuropathic pain by systemic local anesthetics. How, where, and when.
Topics: Anesthetics, Local; Animals; Lidocaine; Pain; Peripheral Nervous System Diseases; Rats | 1995 |
Prolonged alleviation of tactile allodynia by intravenous lidocaine in neuropathic rats.
Topics: Anesthetics, Local; Animals; Dose-Response Relationship, Drug; Injections, Intravenous; Lidocaine; M | 1995 |
Pre-injury lidocaine treatment prevents thermal hyperalgesia and cutaneous thermal abnormalities in a rat model of peripheral neuropathy.
Topics: Animals; Disease Models, Animal; Hyperalgesia; Lidocaine; Ligation; Male; Peripheral Nervous System | 1995 |
Neurotoxicity of lidocaine--does it exist?
Topics: Adult; Anesthesia, Spinal; Animals; Humans; Lidocaine; Peripheral Nervous System Diseases; Sensation | 1995 |
This fight isn't fair.
Topics: Anesthesia, Spinal; Cauda Equina; Humans; Lidocaine; Peripheral Nervous System Diseases; Syndrome | 1994 |
Rhinologic headaches.
Topics: Adult; Cartilage Diseases; Facial Pain; Female; Follow-Up Studies; Headache; Humans; Lidocaine; Male | 1994 |
Concentration dependence of lidocaine-induced irreversible conduction loss in frog nerve.
Topics: Action Potentials; Animals; Calcium Channels; Drug Interactions; In Vitro Techniques; Kinetics; Lido | 1994 |
Modification of the peripheral nerve disturbance in ciguatera poisoning in rats with lidocaine.
Topics: Action Potentials; Animals; Ciguatera Poisoning; Lidocaine; Male; Mice; Neural Conduction; Periphera | 1993 |
Temporomandibular joint pain as a neuropathy.
Topics: Administration, Oral; Drug Therapy, Combination; Facial Pain; Humans; Injections, Intravenous; Lidoc | 1995 |
Transient radicular irritation after single subarachnoid injection of isobaric 2% lignocaine for spinal anaesthesia.
Topics: Adult; Anesthesia, Spinal; Anesthetics, Local; Female; Genitalia, Female; Humans; Lidocaine; Middle | 1996 |
Skin blood flow disturbances in the contralateral limb in a peripheral mononeuropathy in the rat.
Topics: Animals; Capsaicin; Cold Temperature; Electric Stimulation; Functional Laterality; Hindlimb; Lidocai | 1996 |
Absence of transient radicular irritation after 5000 spinal anaesthetics with prilocaine.
Topics: Anesthesia, Spinal; Anesthetics, Local; Humans; Lidocaine; Peripheral Nervous System Diseases; Prilo | 1997 |
Treatment of painful distal sensory polyneuropathy in HIV-infected patients with a topical agent: results of an open-label trial of 5% lidocaine gel.
Topics: Anesthetics, Local; Clinical Trials as Topic; HIV Infections; Humans; Lidocaine; Pain; Peripheral Ne | 1999 |
Spinal nerve function in five volunteers experiencing transient neurologic symptoms after lidocaine subarachnoid anesthesia.
Topics: Adult; Anesthesia, Spinal; Anesthetics, Local; Electromyography; Evoked Potentials, Somatosensory; F | 2000 |
[The predictive lidocaine test in treatment of neuropathic pain].
Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Local; Female; Humans; Lidocaine; Male; Middle Aged; Pa | 2000 |
[Effect of mexiletine on spontaneous sensory afferent activity in spontaneous diabetic rats (WBN/Kob rats)].
Topics: Action Potentials; Anesthetics, Local; Animals; Anti-Arrhythmia Agents; Depression, Chemical; Diabet | 2000 |
Traumatic neuropathy of the intermediate dorsal cutaneous nerve (Lemont's nerve): A case report.
Topics: Adolescent; Athletic Injuries; Female; Foot Injuries; Humans; Lidocaine; Musculocutaneous Nerve; Pai | 1975 |
Neuromyotonia in hereditary motor neuropathy.
Topics: Adolescent; Anti-Arrhythmia Agents; Carbamazepine; Child; Electromyography; Female; Humans; Lidocain | 1991 |
Preservative-free is not antioxidant-free.
Topics: Anesthesia, Epidural; Antioxidants; Drug Contamination; Drug Labeling; Humans; Lidocaine; Peripheral | 1990 |
Teres minor. Source of symptoms resembling ulnar neuropathy or C8 radiculopathy.
Topics: Adult; Diagnosis, Differential; Electrodiagnosis; Female; Humans; Lidocaine; Male; Middle Aged; Myof | 1988 |
Epidural analgesic techniques in the management of cervical pain.
Topics: Adult; Aged; Analgesia; Epidural Space; Female; Humans; Injections; Lidocaine; Male; Middle Aged; Ne | 1986 |
Epidural analgesic techniques in the management of cervical pain.
Topics: Adult; Aged; Analgesia; Epidural Space; Female; Humans; Injections; Lidocaine; Male; Middle Aged; Ne | 1986 |
Epidural analgesic techniques in the management of cervical pain.
Topics: Adult; Aged; Analgesia; Epidural Space; Female; Humans; Injections; Lidocaine; Male; Middle Aged; Ne | 1986 |
Epidural analgesic techniques in the management of cervical pain.
Topics: Adult; Aged; Analgesia; Epidural Space; Female; Humans; Injections; Lidocaine; Male; Middle Aged; Ne | 1986 |
Obturator neuropathy after multiple genitourinary procedures.
Topics: Adult; Female; Humans; Lidocaine; Nerve Block; Obturator Nerve; Peripheral Nervous System Diseases; | 1987 |
Cooperative study on cardiac catheterization. Complications involving the nervous system.
Topics: Adolescent; Adult; Angiocardiography; Cardiac Catheterization; Central Nervous System Diseases; Chil | 1968 |
Neurologic complications following spinal anesthesia with lidocaine: a prospective review of 10,440 cases.
Topics: Adolescent; Adult; Anesthesia, Spinal; Back Pain; Female; Headache; Humans; Lidocaine; Male; Methods | 1969 |
Abdominal cutaneous nerve entrapment syndrome.
Topics: Abdomen; Adult; Aged; Diagnosis, Differential; Female; Humans; Lidocaine; Male; Nerve Compression Sy | 1972 |
Meralgia paresthetica.
Topics: Femoral Nerve; Humans; Inguinal Canal; Lidocaine; Pain; Paresthesia; Peripheral Nervous System Disea | 1972 |
Muscle rigidity in a newborn due to continuous peripheral nerve hyperactivity.
Topics: Action Potentials; Anesthesia, Spinal; Autopsy; Brain; DDT; Electric Stimulation; Electromyography; | 1972 |