lidocaine has been researched along with Parkinson Disease in 14 studies
Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.
Parkinson Disease: A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75)
| Excerpt | Relevance | Reference |
|---|---|---|
| "We report our experience with lidocaine microinjection into the thalamus in 10 patients undergoing stereotactic thalamotomy for the treatment of Parkinsonian or non-Parkinsonian tremor." | 7.68 | Tremor reduction by microinjection of lidocaine during stereotactic surgery. ( Dostrovsky, JO; Parrent, AG; Tasker, RR, 1993) |
| "We report our experience with lidocaine microinjection into the thalamus in 10 patients undergoing stereotactic thalamotomy for the treatment of Parkinsonian or non-Parkinsonian tremor." | 3.68 | Tremor reduction by microinjection of lidocaine during stereotactic surgery. ( Dostrovsky, JO; Parrent, AG; Tasker, RR, 1993) |
| "5 to 2-microliters injections of 2% lidocaine at appropriate sites in the thalamic ventrocaudal or ventrointermedius nucleus can produce a temporary marked suppression of tremor." | 3.68 | Microinjection of lidocaine into human thalamus: a useful tool in stereotactic surgery. ( Davis, KD; Dostrovsky, JO; Hutchison, WD; Parrent, AG; Sher, GD; Tasker, RR, 1993) |
| "In patients with Parkinson's disease, neurones in the STN display hyperactive firing rates and rhythmic discharge activity such as tremor-related oscillations (3-8 Hz) and synchronous high-frequency oscillations (15-30 Hz)." | 1.31 | Lidocaine and muscimol microinjections in subthalamic nucleus reverse Parkinsonian symptoms. ( Dostrovsky, JO; Hutchison, WD; Lang, AE; Levy, R; Lozano, AM; Pahapill, P; Romas, J; Saint-Cyr, J, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (28.57) | 18.7374 |
| 1990's | 2 (14.29) | 18.2507 |
| 2000's | 2 (14.29) | 29.6817 |
| 2010's | 6 (42.86) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Di Martino, S | 1 |
| Unti, E | 1 |
| Tramonti, C | 1 |
| Mazzucchi, S | 1 |
| Bonuccelli, U | 1 |
| Rossi, B | 1 |
| Ceravolo, R | 1 |
| Chisari, C | 1 |
| Tang, W | 1 |
| Wei, P | 1 |
| Huang, J | 1 |
| Zhang, N | 1 |
| Zhou, H | 1 |
| Zhou, J | 1 |
| Zheng, Q | 1 |
| Li, J | 1 |
| Wang, Z | 1 |
| Wijemanne, S | 1 |
| Jimenez-Shahed, J | 1 |
| Chieng, LO | 1 |
| Madhavan, K | 1 |
| Wang, MY | 1 |
| Lester, DB | 1 |
| Rogers, TD | 1 |
| Blaha, CD | 1 |
| Furusawa, Y | 2 |
| Mukai, Y | 2 |
| Kobayashi, Y | 2 |
| Sakamoto, T | 2 |
| Murata, M | 2 |
| Kawazoe, T | 1 |
| Sano, T | 1 |
| Nakamura, H | 1 |
| Sakamoto, C | 1 |
| Iwata, Y | 1 |
| Wakita, M | 1 |
| Nakata, Y | 1 |
| Kamiya, K | 1 |
| Takiyama, Y | 1 |
| Parrent, AG | 2 |
| Tasker, RR | 2 |
| Dostrovsky, JO | 3 |
| Sher, GD | 1 |
| Davis, KD | 1 |
| Hutchison, WD | 2 |
| Levy, R | 1 |
| Lang, AE | 1 |
| Pahapill, P | 1 |
| Romas, J | 1 |
| Saint-Cyr, J | 1 |
| Lozano, AM | 1 |
| Rockswold, GL | 1 |
| Bradley, WE | 1 |
| Chou, SN | 1 |
| Wycis, HT | 1 |
| Spiegel, EA | 1 |
| Szekely, EG | 1 |
| Ditunno, JF | 1 |
| Hayes, JP | 1 |
| Schwartz, H | 1 |
| Jeresaty, RM | 1 |
| Kahn, AH | 1 |
| Landry, AB | 1 |
| Leissner, P | 1 |
| Petersén, I | 1 |
| Sörbye, R | 1 |
1 review available for lidocaine and Parkinson Disease
| Article | Year |
|---|---|
Deep brain stimulation as a treatment for Parkinson's disease related camptocormia.
Topics: Adult; Aged; Antiparkinson Agents; Deep Brain Stimulation; Female; Humans; Levodopa; Lidocaine; Male | 2015 |
1 trial available for lidocaine and Parkinson Disease
| Article | Year |
|---|---|
Long-term effect of repeated lidocaine injections into the external oblique for upper camptocormia in Parkinson's disease.
Topics: Abdominal Muscles; Aged; Anesthetics, Local; Female; Humans; Lidocaine; Male; Muscular Atrophy, Spin | 2013 |
12 other studies available for lidocaine and Parkinson Disease
| Article | Year |
|---|---|
Efficacy of a combined therapeutic approach in the management of Pisa Syndrome.
Topics: Abdominal Muscles; Aged; Anesthetics, Local; Female; Humans; Lidocaine; Male; Middle Aged; Neurologi | 2017 |
Nasotracheal intubation-extubation-intubation and asleep-awake-asleep anesthesia technique for deep brain stimulation.
Topics: Airway Extubation; Anesthesia, General; Bronchoscopy; Deep Brain Stimulation; Female; Fiber Optic Te | 2019 |
Improvement in dystonic camptocormia following botulinum toxin injection to the external oblique muscle.
Topics: Abdominal Muscles; Anesthetics, Local; Female; Humans; Lidocaine; Male; Muscular Atrophy, Spinal; Pa | 2014 |
Neuronal pathways involved in deep brain stimulation of the subthalamic nucleus for treatment of Parkinson's disease.
Topics: Animals; Axons; Deep Brain Stimulation; Electrodes, Implanted; Humans; Lidocaine; Mice; Mice, Inbred | 2009 |
Role of the external oblique muscle in upper camptocormia for patients with Parkinson's disease.
Topics: Abdominal Muscles; Aged; Anesthetics, Local; Female; Humans; Lidocaine; Male; Middle Aged; Muscular | 2012 |
Tremor reduction by microinjection of lidocaine during stereotactic surgery.
Topics: Electric Stimulation Therapy; Female; Humans; Lidocaine; Male; Microinjections; Movement Disorders; | 1993 |
Microinjection of lidocaine into human thalamus: a useful tool in stereotactic surgery.
Topics: Electric Stimulation; Electrocoagulation; Humans; Lidocaine; Microinjections; Multiple Sclerosis; Pa | 1993 |
Lidocaine and muscimol microinjections in subthalamic nucleus reverse Parkinsonian symptoms.
Topics: Aged; Anesthetics, Local; Dyskinesia, Drug-Induced; Female; GABA Agonists; Humans; Injections, Intra | 2001 |
Effect of sacral nerve blocks on the function of the urinary bladder in humans.
Topics: Diabetes Mellitus; Humans; Lidocaine; Lumbosacral Plexus; Multiple Sclerosis; Nerve Block; Pain; Par | 1974 |
Effect of deafferentation of an arm upon the tremor of the opposite arm.
Topics: Arm; Denervation; Electromyography; Humans; Lidocaine; Parkinson Disease; Stereotaxic Techniques; Tr | 1969 |
Sinoatrial arrest due to lidocaine in a patient receiving guinidine.
Topics: Aged; Arrhythmias, Cardiac; Bradycardia; Dopamine; Drug Synergism; Electrocardiography; Heart Arrest | 1972 |
Chlormethiazole, amobarbital, lidocaine and PLT 101 in spasticity and rigidity: a study of clinical and EMG-Registrable effects on intravenous injection.
Topics: Adolescent; Adult; Aged; Amobarbital; Chlormethiazole; Electromyography; Female; Humans; Hypnotics a | 1969 |