lidocaine has been researched along with Pain, Procedural in 52 studies
Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.
Pain, Procedural: Pain associated with examination, treatment or procedures.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Our objective was to compare the effectiveness of local lidocaine spray (LS) compared to forced coughing (FC) for relieving the pain during colposcopically guided cervical biopsies (CGBs)." | 9.30 | Comparison of topical lidocaine spray with forced coughing in pain relief during colposcopic biopsy procedure: a randomised trial. ( Alkış, İ; Çetin, O; Karaman, E; Kolusarı, A, 2019) |
| " The purpose of this study was to measure the effect of hydrocodone/acetaminophen elixir in reducing both pain and anxiety in children undergoing sutured laceration repair in the emergency department." | 5.34 | Evaluation of Hydrocodone/Acetaminophen for Pediatric Laceration Repair: A Randomized Trial. ( Camp, EA; Caviness, AC; Chumpitazi, CE; Grawe, GH; Shah, MI, 2020) |
| "Our objective was to compare the effectiveness of local lidocaine spray (LS) compared to forced coughing (FC) for relieving the pain during colposcopically guided cervical biopsies (CGBs)." | 5.30 | Comparison of topical lidocaine spray with forced coughing in pain relief during colposcopic biopsy procedure: a randomised trial. ( Alkış, İ; Çetin, O; Karaman, E; Kolusarı, A, 2019) |
| "In this cohort study, we surveyed 30 adolescents and young adults at their implant insertion visit about pre-procedure anxiety and pain experienced during lidocaine injection and Nexplanon™ placement." | 4.02 | A Pilot Study to Understand the Adolescent Pain Experience During Contraceptive Implant Insertion. ( Bentsianov, SD; Brandi, K; Chen, P; Shimoni, N, 2021) |
| "Lidocaine gel was noninferior to PCB for reported pain scores (VAS) with dilator placement, with a difference in means of -8 mm (95% CI -21, 5) favoring the gel." | 2.90 | Self-administered lidocaine gel for local anesthesia prior to osmotic dilator placement: a randomized trial. ( Blumenthal, PD; Conti, JA; Lerma, K; Montgomery, C; Schivone, GB; Shaw, KA; Wright, P, 2019) |
| " This study aimed to demonstrate the efficacy and safety of three intrarectal local anesthesia (IRLA) combined with PPNB in patients undergoing transrectal ultrasonography (TRUS)-guided prostate biopsy." | 2.87 | Prospective comparison among three intrarectal anesthetic treatments combined with periprostatic nerve block during transrectal ultrasonography-guided prostate biopsy. ( Campos-Salcedo, JG; Canizalez-Román, A; Parés-Hipólito, J; Sedano-Lozano, A; Shelton, LM; Torres-Gomez, JJ; Valdez-Flores, MA; Valdez-Flores, RA, 2018) |
| " Pharmacokinetic measures were calculated using noncompartmental analysis." | 2.87 | Effect of Coadministration of Lidocaine on the Pain and Pharmacokinetics of Intramuscular Amikacin in Children With Multidrug-Resistant Tuberculosis: A Randomized Crossover Trial. ( Draper, HR; Garcia-Prats, AJ; Hesseling, AC; McIlleron, HM; Norman, J; Rose, PC; Schaaf, HS; Seddon, JA, 2018) |
| "Lidocaine has been shown to be an effective anaesthetic diluent for some intramuscular injections, but has not been investigated with KM in the treatment of adult patients with MDR-TB." | 2.87 | Effect of lidocaine on kanamycin injection-site pain in patients with multidrug-resistant tuberculosis. ( Chirehwa, MT; Court, RG; de Vries, N; Gumbo, T; Harding, J; Maartens, G; McIlleron, H; Stewart, A; Wiesner, L, 2018) |
| " The second evaluation variables included the global aesthetic improvement scale, wrinkle severity rating scale, and adverse events." | 2.84 | The Efficacy and Safety of HA IDF Plus (with Lidocaine) Versus HA IDF (Without Lidocaine) in Nasolabial Folds Injection: A Randomized, Multicenter, Double-Blind, Split-Face Study. ( Kim, SH; Lee, JH; Park, ES, 2017) |
| " lidocaine reduced propofol dosage required for gastrointestinal endoscopic procedures (SMD=-0." | 2.82 | Impact of intravenous and topical lidocaine on clinical outcomes in patients receiving propofol for gastrointestinal endoscopic procedures: a meta-analysis of randomised controlled trials. ( Chang, YJ; Chang, YP; Chen, JY; Ho, CN; Hung, KC; Lan, KM; Lin, YT; Sun, CK; Wang, LK; Yew, M, 2022) |
| " This study aimed to determine the safety and adverse effects seen in patients that receive larger amounts of locally injected lidocaine." | 1.62 | Risk of adverse events due to high volumes of local anesthesia during Mohs micrographic surgery. ( Clayton, A; Danford, BC; Darragh, C; Frank, N; Patrinely, JR; Wheless, L, 2021) |
| "Pre-treatment with lidocaine or flurbiprofen axetil has proven to be effectual in the reduction propofol-induced pain in adults." | 1.56 | Clinical therapeutic effects of lidocaine combination with flurbiprofen axetil for reducing propofol-induced pain in adults: A protocol for systematic review and meta-analysis. ( Fu, J; Lu, G; Sun, W; Ye, X; Yu, J, 2020) |
| "Lipedema is a chronic, progressive disorder of subcutaneous adipose tissue that usually affects the lower extremities of women." | 1.56 | Prevention of Progression of Lipedema With Liposuction Using Tumescent Local Anesthesia: Results of an International Consensus Conference. ( Anderhuber, F; Barsch, M; Faulhaber, J; Habbema, L; Halk, AB; Hanke, CW; Herbst, K; Maier, S; Mindt, S; Moosbauer, W; Pilsl, U; Podda, M; Rapprich, S; Sandhofer, M; Sattler, G; Sattler, S; Schauer, P; Schmeller, W, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 31 (59.62) | 24.3611 |
| 2020's | 21 (40.38) | 2.80 |
| Authors | Studies |
|---|---|
| Hung, KC | 1 |
| Yew, M | 1 |
| Lin, YT | 1 |
| Chen, JY | 1 |
| Wang, LK | 1 |
| Chang, YJ | 1 |
| Chang, YP | 1 |
| Lan, KM | 1 |
| Ho, CN | 1 |
| Sun, CK | 1 |
| Yıldız, İU | 1 |
| Yıldırım, Ç | 1 |
| Özhasenekler, A | 1 |
| Şener, A | 1 |
| Gökhan, Ş | 1 |
| Scribner-O'Pray, M | 1 |
| Taylor, ED | 1 |
| Krause, E | 1 |
| Nickel, A | 1 |
| Bergmann, KR | 1 |
| Homkrun, P | 1 |
| Tongsong, T | 1 |
| Srisupundit, K | 1 |
| Charoenkwan, K | 3 |
| Nantasupha, C | 1 |
| Smoker, J | 1 |
| Cohen, A | 1 |
| Rasouli, MR | 1 |
| Schwenk, ES | 1 |
| Chumpitazi, CE | 1 |
| Caviness, AC | 1 |
| Grawe, GH | 1 |
| Camp, EA | 1 |
| Shah, MI | 1 |
| Vent, A | 1 |
| Surber, C | 1 |
| Graf Johansen, NT | 1 |
| Figueiredo, V | 1 |
| Schönbächler, G | 1 |
| Imhof, L | 1 |
| Buset, C | 1 |
| Hafner, J | 1 |
| Villavicencio, JC | 1 |
| Kulkarni, A | 1 |
| Luis, C | 1 |
| Mendez, H | 1 |
| Raker, C | 1 |
| Cronin, B | 1 |
| Robison, K | 1 |
| Jiang, XY | 1 |
| Jiaji, L | 1 |
| Tao, Z | 1 |
| Shahtaheri, SY | 1 |
| Rad, MT | 1 |
| Yazdi, B | 1 |
| Azami, M | 1 |
| Kamali, A | 1 |
| Flanagan, K | 1 |
| McLean, R | 1 |
| Goldberg, D | 1 |
| Ströck, V | 1 |
| Holmäng, S | 1 |
| Lipp, MB | 1 |
| Butterwick, K | 1 |
| Angra, K | 1 |
| Chunhara, C | 1 |
| Goldman, MP | 1 |
| Rappaport, YH | 1 |
| Beberashvili, I | 1 |
| Zisman, A | 1 |
| Stav, K | 1 |
| Patrinely, JR | 1 |
| Darragh, C | 1 |
| Frank, N | 1 |
| Danford, BC | 1 |
| Wheless, L | 1 |
| Clayton, A | 1 |
| Whited, CW | 1 |
| Lubin, J | 1 |
| Marka, N | 1 |
| Koszewski, IJ | 1 |
| Hoffman, MR | 1 |
| Schoeff, S | 1 |
| Dailey, SH | 1 |
| Avondstondt, AM | 1 |
| Chiu, S | 1 |
| Salamon, C | 1 |
| Sun, W | 1 |
| Yu, J | 1 |
| Lu, G | 1 |
| Ye, X | 1 |
| Fu, J | 1 |
| Bentsianov, SD | 1 |
| Brandi, K | 1 |
| Chen, P | 1 |
| Shimoni, N | 1 |
| Mercier, MP | 1 |
| Blanchette, V | 1 |
| Cantin, V | 1 |
| Brousseau-Foley, M | 1 |
| Nam, SH | 2 |
| Kim, KH | 1 |
| Choi, C | 1 |
| Song, T | 1 |
| Lee, KW | 1 |
| Sargin, MA | 1 |
| Yassa, M | 1 |
| Celik, A | 1 |
| Ergun, E | 1 |
| Tug, N | 1 |
| Elkhouly, NI | 1 |
| Maher, MA | 1 |
| Vasan, A | 1 |
| Baker, JA | 1 |
| Shelby, RA | 1 |
| Soo, MSC | 1 |
| Earp, BE | 1 |
| Stanbury, SJ | 1 |
| Mora, AN | 1 |
| Blazar, PE | 1 |
| Pathak, RA | 1 |
| Thiel, DD | 1 |
| Parker, A | 1 |
| Heckman, MG | 1 |
| Crook, JE | 1 |
| Diehl, NN | 1 |
| Tavlarides, A | 1 |
| Alford, SW | 1 |
| Igel, TC | 1 |
| Latsios, G | 1 |
| Toutouzas, K | 1 |
| Antonopoulos, AS | 1 |
| Melidi, E | 1 |
| Synetos, A | 1 |
| Vogiatzi, G | 1 |
| Stasinopoulou, A | 1 |
| Tsioufis, K | 1 |
| Tsiamis, E | 1 |
| Tousoulis, D | 1 |
| Kwon, HJ | 1 |
| Lee, SJ | 1 |
| Kim, JM | 1 |
| Park, KY | 1 |
| Wongluecha, T | 1 |
| Tantipalakorn, C | 1 |
| Srisomboon, J | 1 |
| Zelickson, BR | 1 |
| Goldberg, LH | 1 |
| Rubenzik, MK | 1 |
| Wu, WJ | 1 |
| Caltagirone, R | 1 |
| Raghavan, VR | 1 |
| Adelgais, K | 1 |
| Roosevelt, GE | 1 |
| Valdez-Flores, RA | 1 |
| Campos-Salcedo, JG | 1 |
| Torres-Gomez, JJ | 1 |
| Sedano-Lozano, A | 1 |
| Parés-Hipólito, J | 1 |
| Shelton, LM | 1 |
| Canizalez-Román, A | 1 |
| Valdez-Flores, MA | 1 |
| Ali, SR | 1 |
| Mohamedbhai, H | 1 |
| Garcia-Prats, AJ | 1 |
| Rose, PC | 1 |
| Draper, HR | 1 |
| Seddon, JA | 1 |
| Norman, J | 1 |
| McIlleron, HM | 1 |
| Hesseling, AC | 1 |
| Schaaf, HS | 1 |
| Moore, PA | 1 |
| Petersilka, GJ | 1 |
| Arweiler, NB | 1 |
| Otto, J | 1 |
| Wittig, T | 1 |
| Court, RG | 1 |
| Wiesner, L | 1 |
| Chirehwa, MT | 1 |
| Stewart, A | 1 |
| de Vries, N | 1 |
| Harding, J | 1 |
| Gumbo, T | 1 |
| McIlleron, H | 1 |
| Maartens, G | 1 |
| Palm, MD | 1 |
| Misell, LM | 1 |
| Conti, JA | 2 |
| Lerma, K | 2 |
| Schneyer, RJ | 1 |
| Hastings, CV | 1 |
| Blumenthal, PD | 2 |
| Shaw, KA | 2 |
| Schivone, GB | 1 |
| Montgomery, C | 1 |
| Wright, P | 1 |
| Bonifacio, CC | 1 |
| Karaman, E | 1 |
| Kolusarı, A | 1 |
| Alkış, İ | 1 |
| Çetin, O | 1 |
| Sussman, RD | 1 |
| Kozirovsky, M | 1 |
| Telegrafi, S | 1 |
| Peyronnet, B | 1 |
| Palmerola, R | 1 |
| Smilen, S | 1 |
| Pape, DM | 1 |
| Rosenblum, N | 1 |
| Nitti, VW | 1 |
| Brucker, BM | 1 |
| Werawatakul, Y | 1 |
| Sothornwit, J | 1 |
| Laopaiboon, M | 1 |
| Lumbiganon, P | 1 |
| Kietpeerakool, C | 1 |
| Piyawetchakarn, R | 1 |
| Vardon Bounes, F | 1 |
| Pichon, X | 1 |
| Ducos, G | 1 |
| Ruiz, J | 1 |
| Samier, C | 1 |
| Silva, S | 1 |
| Sommet, A | 1 |
| Fourcade, O | 1 |
| Conil, JM | 1 |
| Minville, V | 1 |
| Aslan, R | 1 |
| Erbin, A | 1 |
| Celik, S | 1 |
| Ucpinar, B | 1 |
| Eryilmaz, R | 1 |
| Taken, K | 1 |
| Kohli, ML | 1 |
| Vali, R | 1 |
| Amirabadi, A | 1 |
| Frankfurter, CA | 1 |
| Nateghi, A | 1 |
| Marie, E | 1 |
| Shammas, A | 1 |
| Wahba, G | 1 |
| Neshkova, E | 1 |
| Vuille-Lessard, É | 1 |
| Bouin, M | 1 |
| Sandhofer, M | 2 |
| Hanke, CW | 1 |
| Habbema, L | 1 |
| Podda, M | 1 |
| Rapprich, S | 1 |
| Schmeller, W | 1 |
| Herbst, K | 1 |
| Anderhuber, F | 1 |
| Pilsl, U | 1 |
| Sattler, G | 1 |
| Moosbauer, W | 1 |
| Sattler, S | 1 |
| Schauer, P | 1 |
| Faulhaber, J | 1 |
| Maier, S | 1 |
| Barsch, M | 1 |
| Mindt, S | 1 |
| Halk, AB | 1 |
| Lee, JH | 1 |
| Kim, SH | 1 |
| Park, ES | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| "Clinical Study on Pain Control of Cervical Dilation by Lidocaine Solution Injected Into a Single-use Micro-non-invasive Injection Cervical Dilator"[NCT05955768] | 74 participants (Anticipated) | Interventional | 2023-07-21 | Enrolling by invitation | |||
| The Effect of Buffered Lidocaine Versus Nonbuffered Lidocaine on Pain Scores During Infiltration for Vulvar Biopsies[NCT02698527] | 128 participants (Actual) | Interventional | 2015-06-30 | Completed | |||
| The Assessment of Pain Outcomes During Rigid Cystoscopy in Females With and Without the Use of the Rigid Cystoscope Obturator: A Randomized Control Trial[NCT05152199] | 68 participants (Actual) | Interventional | 2021-12-22 | Terminated (stopped due to PI employment status change inhibiting continued recruitment) | |||
| The Impact of Pre-procedure Periurethral Topical Lidocaine Application on Pain Scores After Complex Urodynamic Testing in Women[NCT03390790] | Phase 4 | 134 participants (Actual) | Interventional | 2018-01-25 | Completed | ||
| Effectiveness of Saline Water and Lidocaine Injections for the Treatment of Intractable Plantar Keratoma: A Randomised Feasibility Study[NCT04777227] | 40 participants (Actual) | Interventional | 2015-06-07 | Completed | |||
| Effect of Buffered Lidocaine With Epinephrine in Local Anesthesia During Subcutaneous Implantable Venous Access Devices Insertion: Double Blind Randomized Study.[NCT03628430] | 120 participants (Actual) | Interventional | 2017-01-01 | Completed | |||
| Efficacy of Topical Lidocaine/Prilocaine in Pain Management in Pleurocentesis[NCT05984264] | Phase 4 | 118 participants (Anticipated) | Interventional | 2023-01-01 | Recruiting | ||
| A Double-Blind, Randomized Controlled Trial of Jet Injection of 1% Buffered Lidocaine Versus Topical EMLA for Local Anesthesia Before Lumbar Puncture in Children[NCT01628874] | 66 participants (Actual) | Interventional | 2012-09-30 | Terminated (stopped due to Due to low recruitment numbers, the study was terminated.) | |||
| Comparison of Pain Levels in Fusion Prostate Biopsy and Standard TRUS-Guided Biopsy[NCT03859804] | 252 participants (Actual) | Interventional | 2016-12-01 | Completed | |||
| Self-Administered Lidocaine Gel for Pain Management With IUD Insertion: A Randomized Controlled Trial[NCT02738203] | Phase 3 | 220 participants (Actual) | Interventional | 2016-06-01 | Completed | ||
| Addition of Buprenorphine to Paracervical Block Prior to Osmotic Dilator Insertion for Dilation and Evacuation: A Randomized Controlled Trial[NCT04254081] | Phase 4 | 57 participants (Actual) | Interventional | 2020-05-28 | Completed | ||
| Self-administered Lidocaine Gel for Pain-control During Cervical Preparation for Dilation and Evacuation: A Randomized Controlled Trial[NCT02852434] | Phase 3 | 72 participants (Actual) | Interventional | 2016-07-31 | Completed | ||
| The Comparison of Two Different Techniques of Remifentanil Consumption During Implantable Vascular Access Device Procedures[NCT04749069] | 107 participants (Actual) | Interventional | 2012-08-01 | Completed | |||
| REMIFENTANIL AND LOCAL ANESTHESIA COMPARED WITH LOCAL ANESTHESIA FOR THE INSERTION OF CENTRAL VENOUS CATHETERS IN AWAKE PATIENTS[NCT02206022] | Phase 4 | 90 participants (Actual) | Interventional | 2014-08-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
The success of lumbar puncture was defined as obtaining Cerebrospinal fluid (CSF) on the first attempt and <1000 Red Blood Cells/millimeter cubed (NCT01628874)
Timeframe: Immediately following lumbar puncture
| Intervention | Participants (Count of Participants) |
|---|---|
| EMLA Cream, Then Placebo Via J-Tip | 8 |
| Placebo Cream, Then Lidocaine Via J-Tip | 16 |
The pain score was assessed using the 5-point Neonatal Coding System (NFCS) on a scale of 0-5, with 0 indicating no pain and 5 the highest level of pain. (NCT01628874)
Timeframe: At Needle Insertion
| Intervention | score on a scale (Median) |
|---|---|
| EMLA Cream, Then Placebo Via J-Tip | 5 |
| Placebo Cream, Then Lidocaine Via J-Tip | 5 |
The pain score was assessed using the 5-point Neonatal Coding System (NFCS) on a scale of 0-5, with 0 indicating no pain and 5 the highest level of pain. (NCT01628874)
Timeframe: At time J-TIP is used
| Intervention | score on a scale (Median) |
|---|---|
| EMLA Cream, Then Placebo Via J-Tip | 5 |
| Placebo Cream, Then Lidocaine Via J-Tip | 5 |
The pain score was assessed using the 5-point Neonatal Coding System (NFCS) on a scale of 0-5, with 0 indicating no pain and 5 the highest level of pain. (NCT01628874)
Timeframe: Immediately Post-Procedure
| Intervention | score on a scale (Median) |
|---|---|
| EMLA Cream, Then Placebo Via J-Tip | 0 |
| Placebo Cream, Then Lidocaine Via J-Tip | 0 |
Heart rate was measured at 5 points in time (pre-procedure, application of J-Tip, at LP needle insertion, while the needle is in place, and post-procedure) and was compared for significant differences (NCT01628874)
Timeframe: At 5 specific points during the procedure
| Intervention | Beats per Minute (Mean) | ||||
|---|---|---|---|---|---|
| Pre-procedure | J-Tip application | Needle insertion | Needle in place | Post-procedure | |
| EMLA Cream, Then Placebo Via J-Tip | 154 | 160 | 170 | 172 | 157 |
| Placebo Cream, Then Lidocaine Via J-Tip | 156 | 167 | 169 | 178 | 159 |
"Pain immediately after speculum removal as measured by a Visual Analog Scale (VAS). This scale is 0-100--on the scale 0 had no pain and 100 had worst pain imaginable as anchors. A higher score indicates higher pain." (NCT02738203)
Timeframe: 0-3 minutes after procedure completed
| Intervention | score on a scale (Median) |
|---|---|
| Experimental, IUD Insertion Group | 65 |
| Control, IUD Insertion Group | 59 |
"Pain as measured by a Visual Analog Scale (VAS). This scale is 0-100--on the scale 0 had no pain and 100 had worst pain imaginable as anchors. A higher score indicates higher pain." (NCT02738203)
Timeframe: 30 Minutes prior to procedure
| Intervention | score on a scale (Median) |
|---|---|
| Experimental, IUD Insertion Group | 60 |
| Control, IUD Insertion Group | 59 |
"Pain as measured by a Visual Analog Scale (VAS). This scale is 0-100--on the scale 0 had no pain and 100 had worst pain imaginable as anchors. A higher score indicates higher pain." (NCT02738203)
Timeframe: Immediately prior to procedure; upon arrival to procedure room
| Intervention | score on a scale (Median) |
|---|---|
| Experimental, IUD Insertion Group | 2 |
| Control, IUD Insertion Group | 2 |
"Pain as measured by a Visual Analog Scale (VAS). This scale is 0-100--on the scale 0 had no pain and 100 had worst pain imaginable as anchors. A higher score indicates higher pain." (NCT02738203)
Timeframe: Intraoperative
| Intervention | score on a scale (Median) |
|---|---|
| Experimental, IUD Insertion Group | 7 |
| Control, IUD Insertion Group | 11 |
"Pain as measured by a Visual Analog Scale (VAS). This scale is 0-100--on the scale 0 had no pain and 100 had worst pain imaginable as anchors. A higher score indicates higher pain." (NCT02738203)
Timeframe: Intraoperative
| Intervention | score on a scale (Median) |
|---|---|
| Experimental, IUD Insertion Group | 30 |
| Control, IUD Insertion Group | 38 |
Median pain score on a 0 (no pain) to 10 (worst pain) numeric rating scale 1 hour after osmotic dilator insertion assessed via text message (NCT04254081)
Timeframe: 1 hour after osmotic dilator insertion
| Intervention | score on a scale (Median) |
|---|---|
| Buprenorphine 0.15mg + 1% Lidocaine Paracervical Block | 2 |
| 1% Lidocaine Paracervical Block | 3.5 |
Median pain score on a 0 (no pain) to 10 (worst pain) numeric rating scale 2 hours after osmotic dilator insertion assessed via text message (NCT04254081)
Timeframe: 2 hours after osmotic dilator insertion
| Intervention | score on a scale (Median) |
|---|---|
| Buprenorphine 0.15mg + 1% Lidocaine Paracervical Block | 3 |
| 1% Lidocaine Paracervical Block | 3.5 |
Median pain score on a 0 (no pain) to 10 (worst pain) numeric rating scale 6 hours after osmotic dilator insertion assessed via text message (NCT04254081)
Timeframe: 6 hours after osmotic dilator insertion
| Intervention | score on a scale (Median) |
|---|---|
| Buprenorphine 0.15mg + 1% Lidocaine Paracervical Block | 3 |
| 1% Lidocaine Paracervical Block | 3 |
Median pain score on a 0 (no pain) to 10 (worst pain) numeric rating scale at the time of osmotic dilator insertion (NCT04254081)
Timeframe: Assessed immediately after last dilator inserted
| Intervention | score on a scale (Median) |
|---|---|
| Buprenorphine 0.15mg + 1% Lidocaine Paracervical Block | 3.5 |
| 1% Lidocaine Paracervical Block | 4.0 |
Measured by visual analogue scale (VAS), 0-100, Pain was measured on a 100 mm VAS scale. Lower scores correspond to less pain, higher scores correspond to more pain. (NCT02852434)
Timeframe: Preoperative; 30 minutes prior to procedure
| Intervention | units on a scale (Mean) |
|---|---|
| Self-administered Gel | 47.2 |
| Paracervical Block | 58.7 |
Measured by visual analogue scale (VAS), 0-100, Pain was measured on a 100 mm VAS scale. Lower scores correspond to less pain, higher scores correspond to more pain. (NCT02852434)
Timeframe: Immediately prior to procedure
| Intervention | units on a scale (Mean) |
|---|---|
| Self-administered Gel | 2.6 |
| Paracervical Block | 6.6 |
Measured by visual analogue scale (VAS), 0-100; Pain was measured on a 100 mm VAS scale. Lower scores correspond to less pain, higher scores correspond to more pain. (NCT02852434)
Timeframe: Intraoperative; Immediately (0-30 seconds) following cervical dilation
| Intervention | units on a scale (Mean) |
|---|---|
| Self-administered Gel | 48.4 |
| Paracervical Block | 56.3 |
Measured by visual analogue scale (VAS), 0-100; Pain was measured on a 100 mm VAS scale. Lower scores correspond to less pain, higher scores correspond to more pain. (NCT02852434)
Timeframe: Intraoperative; Immediately following speculum placement
| Intervention | units on a scale (Mean) |
|---|---|
| Self-administered Gel | 24.7 |
| Paracervical Block | 31.2 |
Measured by visual analogue scale (VAS), 0-100; Pain was measured on a 100 mm VAS scale. Lower scores correspond to less pain, higher scores correspond to more pain. (NCT02852434)
Timeframe: Postoperative; Assessed once 10 minutes after procedure
| Intervention | units on a scale (Mean) | ||
|---|---|---|---|
| Overall Pain | Overall Experience | Provider Reported Ease of Insertion | |
| Paracervical Block | 51.7 | 62.4 | 21 |
| Self-administered Gel | 45.4 | 65.2 | 27 |
6 reviews available for lidocaine and Pain, Procedural
| Article | Year |
|---|---|
Impact of intravenous and topical lidocaine on clinical outcomes in patients receiving propofol for gastrointestinal endoscopic procedures: a meta-analysis of randomised controlled trials.
Topics: Anesthesia; Endoscopy, Gastrointestinal; Humans; Lidocaine; Pain, Procedural; Propofol; Randomized C | 2022 |
Factors Associated With Low Procedural Pain Scores Among 1- to 5-Year-Old Patients Undergoing Facial Laceration Repair.
Topics: Anti-Anxiety Agents; Child, Preschool; Epinephrine; Humans; Infant; Lacerations; Lidocaine; Pain; Pa | 2023 |
Methods of pain control during endometrial biopsy: A systematic review and meta-analysis of randomized controlled trials.
Topics: Adolescent; Adult; Aged; Anesthesia, Obstetrical; Anesthetics, Local; Anti-Inflammatory Agents, Non- | 2020 |
Transdermal Lidocaine for Perioperative Pain: a Systematic Review of the Literature.
Topics: Anesthetics, Local; Humans; Lidocaine; Pain, Postoperative; Pain, Procedural; Transdermal Patch | 2019 |
The efficacy of articaine and lidocaine local anaesthetic in child patients.
Topics: Anesthesia, Dental; Anesthesia, Local; Anesthetics, Local; Carticaine; Child; Evidence-Based Dentist | 2018 |
Interventions for intra-operative pain relief during postpartum mini-laparotomy tubal ligation.
Topics: Analgesics, Opioid; Anesthetics, Local; Female; Humans; Infusions, Parenteral; Injections, Intramusc | 2019 |
30 trials available for lidocaine and Pain, Procedural
| Article | Year |
|---|---|
Effectiveness of lidocaine spray on radial arterial puncture pain: A randomized double-blind placebo controlled trial.
Topics: Administration, Cutaneous; Adult; Aged; Aged, 80 and over; Anesthesia, Local; Anesthetics, Local; Do | 2021 |
Effect of Xylocaine spray for analgesia during amniocentesis: a randomized controlled trial.
Topics: Adolescent; Adult; Amniocentesis; Analgesia; Anesthetics, Local; Female; Humans; Lidocaine; Middle A | 2019 |
Evaluation of Hydrocodone/Acetaminophen for Pediatric Laceration Repair: A Randomized Trial.
Topics: Acetaminophen; Administration, Topical; Adolescent; Age Factors; Anxiety; Child; Child, Preschool; D | 2020 |
Buffered lidocaine 1%/epinephrine 1:100,000 with sodium bicarbonate (sodium hydrogen carbonate) in a 3:1 ratio is less painful than a 9:1 ratio: A double-blind, randomized, placebo-controlled, crossover trial.
Topics: Adult; Anesthesia, Local; Anesthetics, Local; Buffers; Cross-Over Studies; Double-Blind Method; Epin | 2020 |
Sensation of Pain Using Buffered Lidocaine for Infiltration Before Vulvar Biopsy: A Randomized Controlled Trial.
Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Local; Biopsy; Double-Blind Method; Female; Humans; Lid | 2020 |
Investigation of a New Catheter on Relieving Pain During Male Cystoscopy - A Randomized Clinical Trial.
Topics: Administration, Topical; Adult; Aged; Anesthesia; Anesthetics, Local; Cystoscopy; Equipment Design; | 2020 |
Clinical Comparison of Adding Sulfate Magnesium and Dexmedetomidine in Axillary Plexus Block for Prolonging the Duration of Sensory and Motor Block: Study Protocol for a Double-blind Randomized Clinical Trial.
Topics: Adolescent; Adult; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthetics; Anesthetics, Loc | 2020 |
Is Meatal Analgesia Necessary for Pain Reduction During Cystoscopy in Females? A Prospective Randomized Study.
Topics: Administration, Topical; Aged; Analgesia; Anesthetics, Local; Cystoscopes; Cystoscopy; Female; Gels; | 2020 |
Periurethral Lidocaine Does Not Decrease Pain After Urodynamic Testing in Women: A Double-Blinded Randomized Control Trial.
Topics: Administration, Topical; Aged; Anesthetics, Local; Diagnostic Techniques, Urological; Double-Blind M | 2021 |
Lidocaine gel versus plain lubricating gel for pain reduction during transrectal sonography (LIPS): A randomized controlled trial.
Topics: Administration, Rectal; Adult; Anesthetics, Local; Endosonography; Female; Gels; Humans; Lidocaine; | 2017 |
Lidocaine and tenoxicam effectiveness for pain relief during Pipelle: Non-randomised double-blind placebo-controlled trial.
Topics: Administration, Intravenous; Adult; Anesthesia, Obstetrical; Anesthetics, Local; Anti-Inflammatory A | 2017 |
Different analgesics prior to intrauterine device insertion: is there any evidence of efficacy?
Topics: Adult; Analgesics; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Female; Humans; Intr | 2017 |
Impact of Sodium Bicarbonate-Buffered Lidocaine on Patient Pain During Image-Guided Breast Biopsy.
Topics: Anesthetics, Local; Buffers; Double-Blind Method; Female; Humans; Image-Guided Biopsy; Lidocaine; Pa | 2017 |
Needle-Free Jet Lidocaine Administration for Preinjection Anesthesia in Trigger Finger Injection: A Randomized Controlled Trial.
Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Local; Female; Glucocorticoids; Humans; Injections, Jet | 2017 |
Timing interval from peri-prostatic block to biopsy impacts procedural pain.
Topics: Adult; Aged; Aged, 80 and over; Anesthesia, Local; Anesthetics, Local; Endoscopic Ultrasound-Guided | 2017 |
Anesthetic ointment only (lidocaine/prilocaine) instead of injectable local lidocaine in trans-radial catheterization: A viable no-needle alternative.
Topics: Administration, Cutaneous; Aged; Anesthesia, Local; Anesthetics, Local; Cardiac Catheterization; Cor | 2017 |
Effect of lidocaine spray during colposcopy-directed cervical biopsy: A randomized controlled trial.
Topics: Adult; Aerosols; Anesthetics, Local; Biopsy; Cervix Uteri; Colposcopy; Female; Humans; Lidocaine; Mi | 2017 |
Finer Needles Reduce Pain Associated With Injection of Local Anesthetic Using a Minimal Insertion Injection Technique.
Topics: Aged; Anesthetics, Local; Female; Head and Neck Neoplasms; Humans; Injections; Lidocaine; Male; Midd | 2018 |
A Randomized Double Blind Trial of Needle-free Injected Lidocaine Versus Topical Anesthesia for Infant Lumbar Puncture.
Topics: Administration, Topical; Anesthetics, Local; Child; Double-Blind Method; Female; Humans; Infant; Inf | 2018 |
Prospective comparison among three intrarectal anesthetic treatments combined with periprostatic nerve block during transrectal ultrasonography-guided prostate biopsy.
Topics: Administration, Topical; Aged; Anesthesia, Local; Anesthetics, Local; Anti-Inflammatory Agents, Non- | 2018 |
Effect of Coadministration of Lidocaine on the Pain and Pharmacokinetics of Intramuscular Amikacin in Children With Multidrug-Resistant Tuberculosis: A Randomized Crossover Trial.
Topics: Adolescent; Amikacin; Anesthetics, Local; Antitubercular Agents; Area Under Curve; Child; Cross-Over | 2018 |
Effect of lidocaine on kanamycin injection-site pain in patients with multidrug-resistant tuberculosis.
Topics: Adult; Anesthetics, Local; Anti-Bacterial Agents; Cross-Over Studies; Female; HIV Infections; Humans | 2018 |
Topical Transdermally Delivered Lidocaine and Benzocaine Compared to Compounded Lidocaine/Tetracaine During Microfocused Ultrasound With Visualization Treatment.
Topics: Administration, Cutaneous; Adult; Anesthetics, Local; Benzocaine; Double-Blind Method; Drug Combinat | 2018 |
Self-administered vaginal lidocaine gel for pain management with intrauterine device insertion: a blinded, randomized controlled trial.
Topics: Adolescent; Adult; Anesthetics, Local; Contraceptive Agents, Female; Double-Blind Method; Female; Hu | 2019 |
Self-administered lidocaine gel for local anesthesia prior to osmotic dilator placement: a randomized trial.
Topics: Abortion, Induced; Adult; Anesthesia, Obstetrical; Anesthetics, Local; California; Female; Gels; Hum | 2019 |
Self-administered lidocaine gel for local anesthesia prior to osmotic dilator placement: a randomized trial.
Topics: Abortion, Induced; Adult; Anesthesia, Obstetrical; Anesthetics, Local; California; Female; Gels; Hum | 2019 |
Self-administered lidocaine gel for local anesthesia prior to osmotic dilator placement: a randomized trial.
Topics: Abortion, Induced; Adult; Anesthesia, Obstetrical; Anesthetics, Local; California; Female; Gels; Hum | 2019 |
Self-administered lidocaine gel for local anesthesia prior to osmotic dilator placement: a randomized trial.
Topics: Abortion, Induced; Adult; Anesthesia, Obstetrical; Anesthetics, Local; California; Female; Gels; Hum | 2019 |
Comparison of topical lidocaine spray with forced coughing in pain relief during colposcopic biopsy procedure: a randomised trial.
Topics: Administration, Topical; Adult; Anesthetics, Local; Cervix Uteri; Colposcopy; Cough; Female; Humans; | 2019 |
Effects of lidocaine spray for reducing pain during endometrial aspiration biopsy: A randomized controlled trial.
Topics: Adult; Anesthetics, Local; Biopsy, Needle; Endometrium; Female; Humans; Lidocaine; Pain, Postoperati | 2019 |
Remifentanil for Procedural Sedation and Analgesia in Central Venous Catheter Insertion: A Randomized, Controlled Trial.
Topics: Aged; Analgesics, Opioid; Anesthetics, Local; Central Venous Catheters; Double-Blind Method; Female; | 2019 |
Remifentanil for Procedural Sedation and Analgesia in Central Venous Catheter Insertion: A Randomized, Controlled Trial.
Topics: Aged; Analgesics, Opioid; Anesthetics, Local; Central Venous Catheters; Double-Blind Method; Female; | 2019 |
Remifentanil for Procedural Sedation and Analgesia in Central Venous Catheter Insertion: A Randomized, Controlled Trial.
Topics: Aged; Analgesics, Opioid; Anesthetics, Local; Central Venous Catheters; Double-Blind Method; Female; | 2019 |
Remifentanil for Procedural Sedation and Analgesia in Central Venous Catheter Insertion: A Randomized, Controlled Trial.
Topics: Aged; Analgesics, Opioid; Anesthetics, Local; Central Venous Catheters; Double-Blind Method; Female; | 2019 |
Periprostatic nerve block alone versus combined with perineal pudendal nerve block or intrarectal local anesthesia during transrectal ultrasound-guided prostate biopsy: A prospective randomized controlled trial.
Topics: Aged; Anesthesia, Local; Anesthetics, Local; Biopsy, Large-Core Needle; Cost-Benefit Analysis; Human | 2019 |
The Efficacy and Safety of HA IDF Plus (with Lidocaine) Versus HA IDF (Without Lidocaine) in Nasolabial Folds Injection: A Randomized, Multicenter, Double-Blind, Split-Face Study.
Topics: Adult; Anesthetics, Local; Dermal Fillers; Double-Blind Method; Female; Humans; Hyaluronic Acid; Lid | 2017 |
16 other studies available for lidocaine and Pain, Procedural
| Article | Year |
|---|---|
Is It Time to Redefine Lidocaine Administration Guidelines in Mohs Surgery?
Topics: Anesthesia, Local; Anesthetics, Local; Dose-Response Relationship, Drug; Drug Administration Schedul | 2020 |
Is bladder tumour fulguration under local anaesthesia more painful than cystoscopy only?
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anesthesia, Local; Anesthetics, Local; Biopsy; Cystoscop | 2020 |
Evaluation of Long-Term Outcome and Patient Satisfaction Results After Tumescent Liposuction.
Topics: Anesthesia, Local; Anesthetics, Local; Esthetics; Female; Follow-Up Studies; Humans; Lidocaine; Lipe | 2020 |
Risk of adverse events due to high volumes of local anesthesia during Mohs micrographic surgery.
Topics: Aged; Anesthesia, Local; Anesthetics, Local; Female; Humans; Lidocaine; Male; Middle Aged; Mohs Surg | 2021 |
Pain Experience and Tolerance of Awake In-Office Upper Airway Procedures: Influencing Factors.
Topics: Administration, Topical; Adult; Aged; Ambulatory Surgical Procedures; Anesthesia, Local; Biopsy; Fem | 2021 |
Clinical therapeutic effects of lidocaine combination with flurbiprofen axetil for reducing propofol-induced pain in adults: A protocol for systematic review and meta-analysis.
Topics: Adult; Anesthetics, Intravenous; Anesthetics, Local; Drug Therapy, Combination; Flurbiprofen; Humans | 2020 |
A Pilot Study to Understand the Adolescent Pain Experience During Contraceptive Implant Insertion.
Topics: Adolescent; Anesthetics, Local; Anxiety; Cohort Studies; Contraceptive Agents, Female; Desogestrel; | 2021 |
Effectiveness of saline water and lidocaine injection treatment of intractable plantar keratoma: a randomised feasibility study.
Topics: Aged; Anesthetics, Local; Callosities; Debridement; Feasibility Studies; Female; Humans; Injections; | 2021 |
Topical brimonidine gel for extended-duration local anaesthesia.
Topics: Adrenergic alpha-2 Receptor Agonists; Anesthesia, Local; Anesthetics, Local; Brimonidine Tartrate; E | 2018 |
Lidocaine analgesia for removal of vacuum-assisted closure dressings.
Topics: Analgesia; Anesthetics, Local; Humans; Lidocaine; Negative-Pressure Wound Therapy; Occlusive Dressin | 2018 |
Innovations in Local Anesthesia are Easing the Pain of Dentistry.
Topics: Anesthesia, Local; Anesthetics, Local; Bupivacaine; Dental Care; Drug Combinations; Humans; Lidocain | 2018 |
Non-interventional study to collect data for the application of lidocaine gel 2% during scaling and root planing and professional mechanical plaque removal.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Anesthetics, Local; Dental Plaque; Dental S | 2019 |
Gel-Infused Translabial Ultrasound in the Evaluation of Female Urethral Stricture.
Topics: Anesthetics, Local; Cystoscopy; Female; Humans; Lidocaine; Middle Aged; Outcome Assessment, Health C | 2020 |
Procedural pain reduction strategies in paediatric nuclear medicine.
Topics: Administration, Topical; Anesthetics, Local; Child; Child, Preschool; Combined Modality Therapy; Fem | 2019 |
Is topical lidocaine beneficial before catheter insertion in esophageal manometry and ambulatory pH monitoring?
Topics: Administration, Topical; Adult; Aged; Anesthetics, Local; Case-Control Studies; Esophageal Motility | 2019 |
Prevention of Progression of Lipedema With Liposuction Using Tumescent Local Anesthesia: Results of an International Consensus Conference.
Topics: Anesthesia, Local; Anesthetics, Local; Consensus Development Conferences as Topic; Disease Progressi | 2020 |