Page last updated: 2024-10-28

lidocaine and Out-of-Hospital Cardiac Arrest

lidocaine has been researched along with Out-of-Hospital Cardiac Arrest in 33 studies

Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.

Out-of-Hospital Cardiac Arrest: Occurrence of heart arrest in an individual when there is no immediate access to medical personnel or equipment.

Research Excerpts

ExcerptRelevanceReference
"Amiodarone and lidocaine have not been shown to have a clear survival benefit compared to placebo for out-of-hospital cardiac arrest (OHCA)."9.69Survival by time-to-administration of amiodarone, lidocaine, or placebo in shock-refractory out-of-hospital cardiac arrest. ( Daya, MR; Jui, J; Lupton, JR; Neth, MR; Newgard, CD; Sahni, R; Wittwer, L, 2023)
"In this randomized, double-blind trial, we compared parenteral amiodarone, lidocaine, and saline placebo, along with standard care, in adults who had nontraumatic out-of-hospital cardiac arrest, shock-refractory ventricular fibrillation or pulseless ventricular tachycardia after at least one shock, and vascular access."9.22Amiodarone, Lidocaine, or Placebo in Out-of-Hospital Cardiac Arrest. ( Aufderheide, TP; Brienza, AM; Brown, SP; Callaway, CW; Christenson, J; Colella, MR; Daya, M; Desvigne-Nickens, P; Dorian, P; Dunford, JV; Egan, D; Gray, PC; Gray, R; Idris, AH; Kudenchuk, PJ; Leroux, B; Morrison, LJ; Nichol, G; Ornato, JP; Rea, T; Seals, N; Stiell, IG; Straight, R; Vaillancourt, C; Vilke, GM; Weisfeldt, ML; Wittwer, L, 2016)
"Clinical trials for patients with shock-refractory out-of-hospital cardiac arrest (OHCA), including the Amiodarone, Lidocaine or Placebo (ALPS) trial, have been unable to demonstrate definitive benefit after treatment with antiarrhythmic drugs."8.12Bayesian analysis of amiodarone or lidocaine versus placebo for out-of-hospital cardiac arrest. ( Christenson, J; Davis, D; Daya, MR; Dorian, P; Grunau, B; Kudenchuk, P; Lane, DJ; Lupton, J; Okubo, M; Rea, T; Scheuermeyer, F; Vaillancourt, C; Wang, HE; Yannopoulos, D, 2022)
" We included adult patients with shockable rhythms, such as ventricular fibrillation and pulseless ventricular tachycardia, who were administered either lidocaine or amiodarone."8.12Comparison of the effects of lidocaine and amiodarone for out-of-hospital cardiac arrest patients with shockable rhythms: a retrospective observational study from a multicenter registry. ( Amagasa, S; Fukushima, F; Kashiura, M; Kishihara, Y; Moriya, T; Yasuda, H, 2022)
"International guidelines recommend amiodarone for out-of-hospital cardiac arrest (OHCA) in refractory ventricular fibrillation (VF)."8.02Time to amiodarone administration and survival outcomes in refractory ventricular fibrillation. ( Bosley, E; Doan, TN; Rashford, S; Schultz, BV; Wilson, D; Wissa, J, 2021)
"The latest resuscitation guidelines recommend the use of amiodarone in adult patients with out-of-hospital cardiac arrest (OHCA) and refractory ventricular fibrillation (VF) to improve the rates of return of spontaneous circulation."7.83Amiodarone Compared with Lidocaine for Out-Of-Hospital Cardiac Arrest with Refractory Ventricular Fibrillation on Hospital Arrival: a Nationwide Database Study. ( Fushimi, K; Ishinokami, S; Kaneko, J; Kuno, M; Matsui, H; Tagami, T; Tanaka, C; Unemoto, K; Yasunaga, H, 2016)
"Antiarrhythmic drugs like lidocaine are usually given to promote return of spontaneous circulation (ROSC) during ongoing out-of-hospital cardiac arrest (OHCA) from ventricular fibrillation/tachycardia (VF/VT)."7.79Prophylactic lidocaine for post resuscitation care of patients with out-of-hospital ventricular fibrillation cardiac arrest. ( Eisenberg, M; Fahrenbruch, C; Kudenchuk, PJ; Newell, C; Rea, T; White, L, 2013)
"Background The effects of amiodarone and lidocaine on the return of spontaneous circulation (ROSC) in relation to time to treatment in patients with out-of-hospital cardiac arrest is not known."5.51Effect of Time to Treatment With Antiarrhythmic Drugs on Return of Spontaneous Circulation in Shock-Refractory Out-of-Hospital Cardiac Arrest. ( Cheskes, S; Dorian, P; Lebovic, G; Lin, S; Rahimi, M, 2022)
"In this prespecified analysis of a randomized, placebo-controlled clinical trial, we compared the differences in survival to hospital discharge in adults with shock-refractory ventricular fibrillation/pulseless ventricular tachycardia out-of-hospital cardiac arrest who were randomly assigned by emergency medical services personnel to an antiarrhythmic drug versus placebo in the ALPS trial (Resuscitation Outcomes Consortium Amiodarone, Lidocaine or Placebo Study), when stratified by the intravenous versus intraosseous route of administration."5.34Survival After Intravenous Versus Intraosseous Amiodarone, Lidocaine, or Placebo in Out-of-Hospital Shock-Refractory Cardiac Arrest. ( Barbic, D; Christenson, J; Daya, MR; Dorian, P; Herdeman, C; Idris, A; Kudenchuk, PJ; Leroux, BG; Lupton, JR; Menegazzi, JJ; Mody, P; Morrison, LJ; Newgard, CD; Ornato, JP; Rea, TD; Sopko, G; Vilke, GM, 2020)
"In this randomized, double-blind trial, we compared parenteral amiodarone, lidocaine, and saline placebo, along with standard care, in adults who had nontraumatic out-of-hospital cardiac arrest, shock-refractory ventricular fibrillation or pulseless ventricular tachycardia after at least one shock, and vascular access."5.22Amiodarone, Lidocaine, or Placebo in Out-of-Hospital Cardiac Arrest. ( Aufderheide, TP; Brienza, AM; Brown, SP; Callaway, CW; Christenson, J; Colella, MR; Daya, M; Desvigne-Nickens, P; Dorian, P; Dunford, JV; Egan, D; Gray, PC; Gray, R; Idris, AH; Kudenchuk, PJ; Leroux, B; Morrison, LJ; Nichol, G; Ornato, JP; Rea, T; Seals, N; Stiell, IG; Straight, R; Vaillancourt, C; Vilke, GM; Weisfeldt, ML; Wittwer, L, 2016)
"Guidelines for treatment of out-of-hospital cardiac arrest (OOH-CA) with shockable rhythm recommend amiodarone, while lidocaine may be used if amiodarone is not available."4.93Amiodarone or lidocaine for cardiac arrest: A systematic review and meta-analysis. ( Arcadipane, A; Corredor, C; Panarello, G; Pellis, T; Ristagno, G; Sanfilippo, F; Santonocito, C, 2016)
"American Heart Association Advanced Cardiac Life Support (ACLS) guidelines support the use of either amiodarone or lidocaine for cardiac arrest caused by ventricular tachycardia or ventricular fibrillation (VT/VF) based on studies of out-of-hospital cardiac arrest."4.31Comparative Effectiveness of Amiodarone and Lidocaine for the Treatment of In-Hospital Cardiac Arrest. ( Bradley, SM; Cranford, JA; Kronick, SL; Nawer, H; Neumar, RW; Wagner, D, 2023)
"Clinical trials for patients with shock-refractory out-of-hospital cardiac arrest (OHCA), including the Amiodarone, Lidocaine or Placebo (ALPS) trial, have been unable to demonstrate definitive benefit after treatment with antiarrhythmic drugs."4.12Bayesian analysis of amiodarone or lidocaine versus placebo for out-of-hospital cardiac arrest. ( Christenson, J; Davis, D; Daya, MR; Dorian, P; Grunau, B; Kudenchuk, P; Lane, DJ; Lupton, J; Okubo, M; Rea, T; Scheuermeyer, F; Vaillancourt, C; Wang, HE; Yannopoulos, D, 2022)
" We included adult patients with shockable rhythms, such as ventricular fibrillation and pulseless ventricular tachycardia, who were administered either lidocaine or amiodarone."4.12Comparison of the effects of lidocaine and amiodarone for out-of-hospital cardiac arrest patients with shockable rhythms: a retrospective observational study from a multicenter registry. ( Amagasa, S; Fukushima, F; Kashiura, M; Kishihara, Y; Moriya, T; Yasuda, H, 2022)
"International guidelines recommend amiodarone for out-of-hospital cardiac arrest (OHCA) in refractory ventricular fibrillation (VF)."4.02Time to amiodarone administration and survival outcomes in refractory ventricular fibrillation. ( Bosley, E; Doan, TN; Rashford, S; Schultz, BV; Wilson, D; Wissa, J, 2021)
"Antiarrhythmic drugs like lidocaine are usually given to promote return of spontaneous circulation (ROSC) during ongoing out-of-hospital cardiac arrest (OHCA) from ventricular fibrillation/tachycardia (VF/VT)."3.79Prophylactic lidocaine for post resuscitation care of patients with out-of-hospital ventricular fibrillation cardiac arrest. ( Eisenberg, M; Fahrenbruch, C; Kudenchuk, PJ; Newell, C; Rea, T; White, L, 2013)
"Amiodarone and lidocaine were the only agents associated with improved survival to hospital admission in the NMA."2.55Comparative effectiveness of antiarrhythmics for out-of-hospital cardiac arrest: A systematic review and network meta-analysis. ( Brignardello-Petersen, R; Cheskes, S; Guyatt, G; Iansavichene, A; McLeod, SL; Worster, A; You, J, 2017)

Research

Studies (33)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's21 (63.64)24.3611
2020's12 (36.36)2.80

Authors

AuthorsStudies
Lane, DJ1
Grunau, B2
Kudenchuk, P1
Dorian, P8
Wang, HE2
Daya, MR3
Lupton, J1
Vaillancourt, C3
Okubo, M1
Davis, D1
Rea, T4
Yannopoulos, D1
Christenson, J3
Scheuermeyer, F1
Rahimi, M2
Cheskes, S4
Lebovic, G2
Lin, S2
Huebinger, R2
Chan, HK2
Bobrow, B1
Chavez, S1
Schulz, K1
Gordon, R1
Jarvis, J1
Harvin, JA1
Idris, A2
Cooper, B1
Giordano, J1
Wagner, D1
Kronick, SL1
Nawer, H1
Cranford, JA1
Bradley, SM1
Neumar, RW2
Kishihara, Y1
Kashiura, M1
Amagasa, S1
Fukushima, F1
Yasuda, H1
Moriya, T1
Lupton, JR2
Neth, MR1
Sahni, R1
Jui, J1
Wittwer, L3
Newgard, CD2
Jouffroy, R1
Ecollan, P1
Chollet-Xemard, C1
Prunet, B1
Elie, C1
Treluyer, JM1
Vivien, B1
Leroux, BG1
Rea, TD1
Morrison, LJ4
Menegazzi, JJ2
Ornato, JP2
Sopko, G1
Mody, P1
Vilke, GM2
Herdeman, C1
Barbic, D1
Kudenchuk, PJ6
Ludwin, K1
Smereka, J1
Nadolny, K1
Ładny, JR1
Szarpak, A1
Fajfer, Z1
Jaguszewski, M1
Filipiak, KJ1
Szarpak, Ł1
Wissa, J1
Schultz, BV1
Wilson, D1
Rashford, S1
Bosley, E1
Doan, TN1
Tagami, T2
Yasunaga, H2
Yokota, H1
McLeod, SL1
Brignardello-Petersen, R1
Worster, A1
You, J1
Iansavichene, A1
Guyatt, G1
Soar, J3
Salcido, DD1
Schmicker, RH1
Kime, N1
Buick, JE1
Zellner, S1
Zive, D1
Aufderheide, TP2
Koller, AC1
Herren, H1
Nuttall, J1
Sundermann, ML1
Ali, MU1
Fitzpatrick-Lewis, D1
Kenny, M1
Raina, P1
Atkins, DL3
Nolan, J1
Ristagno, G3
Sherifali, D1
Donnino, MW1
Maconochie, I1
Aickin, R1
Andersen, LW1
Berg, KM1
Bingham, R1
Böttiger, BW1
Callaway, CW2
Couper, K1
Couto, TB1
de Caen, AR1
Deakin, CD1
Drennan, IR1
Guerguerian, AM1
Lavonas, EJ1
Meaney, PA1
Nadkarni, VM1
Ng, KC1
Nicholson, TC1
Nuthall, GA1
Ohshimo, S1
O'Neil, BJ1
Ong, GY1
Paiva, EF1
Parr, MJ1
Reis, AG1
Reynolds, JC1
Sandroni, C1
Schexnayder, SM1
Scholefield, BR1
Shimizu, N1
Tijssen, JA1
Van de Voorde, P1
Wang, TL1
Welsford, M1
Hazinski, MF2
Nolan, JP1
Morley, PT1
Duff, JP1
Topjian, A1
Berg, MD1
Chan, M1
Haskell, SE1
Joyner, BL1
Lasa, JJ1
Ley, SJ1
Raymond, TT1
Sutton, RM1
Newell, C1
White, L1
Fahrenbruch, C1
Eisenberg, M1
Brown, SP3
Daya, M4
Grunau, BE1
Aufderheide, T1
Powell, J2
Leroux, B3
Larsen, J1
Colella, MR2
Stephens, SW1
Gamber, M1
Egan, D2
Iannone, P1
Joglar, JA1
Page, RL1
Nichol, G1
Weisfeldt, ML1
Stiell, IG1
Idris, AH1
Dunford, JV1
Brienza, AM1
Desvigne-Nickens, P1
Gray, PC1
Gray, R1
Seals, N1
Straight, R1
Mumma, BE1
Umarov, T1
Sanfilippo, F1
Corredor, C1
Santonocito, C1
Panarello, G1
Arcadipane, A1
Pellis, T1
Pollak, PT1
Spence, JD1
Patel, JJ1
Matsui, H1
Tanaka, C1
Kaneko, J1
Kuno, M1
Ishinokami, S1
Unemoto, K1
Fushimi, K1
Huang, CH1
Yu, PH1
Tsai, MS1
Chuang, PY1
Wang, TD1
Chiang, CY1
Chang, WT1
Ma, MH1
Tang, CH1
Chen, WJ1
Lang, ES1
Browning, K1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
aMsa and amiOdarone Study in cArdiaC Arrest[NCT04997980]500 participants (Anticipated)Observational2015-01-01Recruiting
Etiology, Incidence and Survival of Pediatric Out-of-hospital Cardiac Arrests: a Four-year Danish Analysis[NCT04275856]300 participants (Anticipated)Observational [Patient Registry]2019-02-01Active, not recruiting
Amiodarone, Lidocaine or Neither for Out-Of-Hospital Cardiac Arrest Due to Ventricular Fibrillation (VF) or Ventricular Tachycardia (VT)[NCT01401647]Phase 33,024 participants (Actual)Interventional2012-05-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Number of Participants Scoring at or Below a 3 on the MRS Scale

Neurologic status at discharge will be assessed using the modified Rankin Score (MRS). A higher value indicates a worse outcome. 0-No symptoms at all; 1-No significant disability despite symptoms; able to carry out all usual duties and activities, 2-Slight disability; unable to carry out all previous activities, but able to look after own affairs without assistance, 3-Moderate disability; requiring some help, but able to walk without assistance; 4-Moderately severe disability; unable to walk without assistance and unable to attend to own bodily needs without assistance, 5-Severe disability; bedridden, incontinent and requiring constant nursing care and attention; 6-Dead (NCT01401647)
Timeframe: Patients will be followed from the time of the cardiac arrest until death, hospital discharge, or December 31, 2015, whichever occurs first.

InterventionParticipants (Count of Participants)
Amiodarone182
Lidocaine172
Normal Saline175

Number of Participants Who Survive From the Time of Cardiac Arrest to Hospital Discharge

Patients may die in the field (outside of the hospital at the time of the cardiac arrest), at the emergency room, in the hospital, or they are discharged alive from the hospital. (NCT01401647)
Timeframe: Patients will be followed from the time of the cardiac arrest until death, hospital discharge, or December 31, 2015, whichever occurs first.

Interventionparticipants (Number)
Amiodarone237
Lidocaine233
Normal Saline222

Reviews

7 reviews available for lidocaine and Out-of-Hospital Cardiac Arrest

ArticleYear
Effect of amiodarone and lidocaine on shock-refractory cardiac arrest: a systematic review and meta-analysis.
    Kardiologia polska, 2020, 10-23, Volume: 78, Issue:10

    Topics: Amiodarone; Anti-Arrhythmia Agents; Cardiopulmonary Resuscitation; Cross-Sectional Studies; Humans;

2020
Antiarrhythmic drugs for out-of-hospital cardiac arrest with refractory ventricular fibrillation.
    Critical care (London, England), 2017, Mar-21, Volume: 21, Issue:1

    Topics: Amiodarone; Anti-Arrhythmia Agents; Emergency Medical Services; Humans; Intensive Care Units; Lidoca

2017
Comparative effectiveness of antiarrhythmics for out-of-hospital cardiac arrest: A systematic review and network meta-analysis.
    Resuscitation, 2017, Volume: 121

    Topics: Amiodarone; Anti-Arrhythmia Agents; Bretylium Compounds; Humans; Lidocaine; Network Meta-Analysis; O

2017
Antiarrhythmic drug therapy during cardiopulmonary resuscitation: should we use it?
    Current opinion in critical care, 2018, Volume: 24, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cardiopulm

2018
Effectiveness of antiarrhythmic drugs for shockable cardiac arrest: A systematic review.
    Resuscitation, 2018, Volume: 132

    Topics: Adult; Amiodarone; Anti-Arrhythmia Agents; Cardiopulmonary Resuscitation; Child; Female; Humans; Lid

2018
Amiodarone or lidocaine for cardiac arrest: A systematic review and meta-analysis.
    Resuscitation, 2016, Volume: 107

    Topics: Amiodarone; Anti-Arrhythmia Agents; Cardiopulmonary Resuscitation; Hospitalization; Humans; Lidocain

2016
Ventricular tachyarrhythmias (out-of-hospital cardiac arrests).
    BMJ clinical evidence, 2010, Dec-21, Volume: 2010

    Topics: Amiodarone; Death, Sudden, Cardiac; Electric Countershock; Humans; Hypothermia, Induced; Lidocaine;

2010

Trials

6 trials available for lidocaine and Out-of-Hospital Cardiac Arrest

ArticleYear
Effect of Time to Treatment With Antiarrhythmic Drugs on Return of Spontaneous Circulation in Shock-Refractory Out-of-Hospital Cardiac Arrest.
    Journal of the American Heart Association, 2022, 03-15, Volume: 11, Issue:6

    Topics: Adult; Amiodarone; Anti-Arrhythmia Agents; Cardiopulmonary Resuscitation; Humans; Lidocaine; Out-of-

2022
Survival by time-to-administration of amiodarone, lidocaine, or placebo in shock-refractory out-of-hospital cardiac arrest.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2023, Volume: 30, Issue:9

    Topics: Amiodarone; Anti-Arrhythmia Agents; Cardiopulmonary Resuscitation; Emergency Medical Services; Hospi

2023
Survival After Intravenous Versus Intraosseous Amiodarone, Lidocaine, or Placebo in Out-of-Hospital Shock-Refractory Cardiac Arrest.
    Circulation, 2020, 01-21, Volume: 141, Issue:3

    Topics: Administration, Intravenous; Aged; Amiodarone; Disease-Free Survival; Double-Blind Method; Female; H

2020
Effects of intra-resuscitation antiarrhythmic administration on rearrest occurrence and intra-resuscitation ECG characteristics in the ROC ALPS trial.
    Resuscitation, 2018, Volume: 129

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Canada; Cardiopulmonary Resuscitation; Electrocardiography

2018
Resuscitation Outcomes Consortium-Amiodarone, Lidocaine or Placebo Study (ROC-ALPS): Rationale and methodology behind an out-of-hospital cardiac arrest antiarrhythmic drug trial.
    American heart journal, 2014, Volume: 167, Issue:5

    Topics: Adolescent; Adult; Amiodarone; Anti-Arrhythmia Agents; Cardiopulmonary Resuscitation; Dose-Response

2014
Amiodarone, Lidocaine, or Placebo in Out-of-Hospital Cardiac Arrest.
    The New England journal of medicine, 2016, May-05, Volume: 374, Issue:18

    Topics: Adult; Aged; Amiodarone; Anti-Arrhythmia Agents; Cardiopulmonary Resuscitation; Central Nervous Syst

2016

Other Studies

20 other studies available for lidocaine and Out-of-Hospital Cardiac Arrest

ArticleYear
Bayesian analysis of amiodarone or lidocaine versus placebo for out-of-hospital cardiac arrest.
    Heart (British Cardiac Society), 2022, 10-28, Volume: 108, Issue:22

    Topics: Adult; Amiodarone; Anti-Arrhythmia Agents; Bayes Theorem; Humans; Lidocaine; Out-of-Hospital Cardiac

2022
Time to Antiarrhythmic and Association with Return of Spontaneous Circulation in the United States.
    Prehospital emergency care, 2023, Volume: 27, Issue:2

    Topics: Adult; Amiodarone; Anti-Arrhythmia Agents; Cardiopulmonary Resuscitation; Emergency Medical Services

2023
Procainamide for shockable rhythm cardiac arrest in the Resuscitation Outcome Consortium.
    The American journal of emergency medicine, 2022, Volume: 55

    Topics: Amiodarone; Anti-Arrhythmia Agents; Cardiopulmonary Resuscitation; Emergency Medical Services; Human

2022
Comparative Effectiveness of Amiodarone and Lidocaine for the Treatment of In-Hospital Cardiac Arrest.
    Chest, 2023, Volume: 163, Issue:5

    Topics: Adult; Amiodarone; Anti-Arrhythmia Agents; Cardiopulmonary Resuscitation; Hospitals; Humans; Lidocai

2023
Comparison of the effects of lidocaine and amiodarone for out-of-hospital cardiac arrest patients with shockable rhythms: a retrospective observational study from a multicenter registry.
    BMC cardiovascular disorders, 2022, 11-05, Volume: 22, Issue:1

    Topics: Adult; Amiodarone; Cardiopulmonary Resuscitation; Electric Countershock; Emergency Medical Services;

2022
Evaluation of the effectiveness of potassium chloride in the management of out-of hospital cardiac arrest by refractory ventricular fibrillation: Study protocol of the POTACREH study.
    PloS one, 2023, Volume: 18, Issue:4

    Topics: Amiodarone; Cardiopulmonary Resuscitation; Clinical Trials, Phase II as Topic; Electric Countershock

2023
The Effect of Time to Treatment With Antiarrhythmic Drugs on Survival and Neurological Outcomes in Shock Refractory Out-of-Hospital Cardiac Arrest.
    Critical care medicine, 2023, Jul-01, Volume: 51, Issue:7

    Topics: Adult; Amiodarone; Anti-Arrhythmia Agents; Cardiopulmonary Resuscitation; Humans; Lidocaine; Out-of-

2023
Time to amiodarone administration and survival outcomes in refractory ventricular fibrillation.
    Emergency medicine Australasia : EMA, 2021, Volume: 33, Issue:6

    Topics: Adult; Amiodarone; Anti-Arrhythmia Agents; Cardiopulmonary Resuscitation; Emergency Medical Services

2021
2018 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations Summary.
    Circulation, 2018, 12-04, Volume: 138, Issue:23

    Topics: Amiodarone; Anti-Arrhythmia Agents; Cardiopulmonary Resuscitation; Consensus; Emergency Medical Serv

2018
2018 American Heart Association Focused Update on Pediatric Advanced Life Support: An Update to the American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care.
    Circulation, 2018, 12-04, Volume: 138, Issue:23

    Topics: American Heart Association; Amiodarone; Anti-Arrhythmia Agents; Cardiopulmonary Resuscitation; Child

2018
Prophylactic lidocaine for post resuscitation care of patients with out-of-hospital ventricular fibrillation cardiac arrest.
    Resuscitation, 2013, Volume: 84, Issue:11

    Topics: Aged; Anti-Arrhythmia Agents; Cardiopulmonary Resuscitation; Emergency Medical Services; Female; Hum

2013
Letter to the editor regarding manuscript "resuscitation outcomes consortium-amiodarone, lidocaine or placebo: rationale and methodology behind out-of-hospital cardiac arrest antiarrhythmic drug trial".
    American heart journal, 2014, Volume: 168, Issue:4

    Topics: Amiodarone; Cardiopulmonary Resuscitation; Female; Humans; Lidocaine; Male; Out-of-Hospital Cardiac

2014
Regarding manuscript: "resuscitation outcomes consortium-amiodarone, lidocaine, or placebo study: rationale and methodology behind out-of-hospital cardiac arrest antiarrhythmic drug trial".
    American heart journal, 2014, Volume: 168, Issue:4

    Topics: Amiodarone; Cardiopulmonary Resuscitation; Female; Humans; Lidocaine; Male; Out-of-Hospital Cardiac

2014
Out-of-Hospital Cardiac Arrest--Are Drugs Ever the Answer?
    The New England journal of medicine, 2016, May-05, Volume: 374, Issue:18

    Topics: Amiodarone; Anti-Arrhythmia Agents; Female; Humans; Lidocaine; Male; Out-of-Hospital Cardiac Arrest

2016
Sex differences in the prehospital management of out-of-hospital cardiac arrest.
    Resuscitation, 2016, Volume: 105

    Topics: Aged; Aged, 80 and over; Amiodarone; Arrhythmias, Cardiac; Atropine; Cardiopulmonary Resuscitation;

2016
Amiodarone, Lidocaine, or Placebo in Out-of-Hospital Cardiac Arrest.
    The New England journal of medicine, 2016, 08-25, Volume: 375, Issue:8

    Topics: Amiodarone; Anti-Arrhythmia Agents; Cardiopulmonary Resuscitation; Emergency Medical Services; Heart

2016
Amiodarone, Lidocaine, or Placebo in Out-of-Hospital Cardiac Arrest.
    The New England journal of medicine, 2016, 08-25, Volume: 375, Issue:8

    Topics: Amiodarone; Anti-Arrhythmia Agents; Cardiopulmonary Resuscitation; Emergency Medical Services; Heart

2016
Amiodarone, Lidocaine, or Placebo in Out-of-Hospital Cardiac Arrest.
    The New England journal of medicine, 2016, 08-25, Volume: 375, Issue:8

    Topics: Amiodarone; Anti-Arrhythmia Agents; Cardiopulmonary Resuscitation; Emergency Medical Services; Heart

2016
Amiodarone Compared with Lidocaine for Out-Of-Hospital Cardiac Arrest with Refractory Ventricular Fibrillation on Hospital Arrival: a Nationwide Database Study.
    Cardiovascular drugs and therapy, 2016, Volume: 30, Issue:5

    Topics: Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Databases, Factual; Female; Hospital Mo

2016
Acute hospital administration of amiodarone and/or lidocaine in shockable patients presenting with out-of-hospital cardiac arrest: A nationwide cohort study.
    International journal of cardiology, 2017, Jan-15, Volume: 227

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Cardiopulmonary Resuscitation; Electric Countershock; Fema

2017