lidocaine has been researched along with Osteoarthritis in 39 studies
Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.
Osteoarthritis: A progressive, degenerative joint disease, the most common form of arthritis, especially in older persons. The disease is thought to result not from the aging process but from biochemical changes and biomechanical stresses affecting articular cartilage. In the foreign literature it is often called osteoarthrosis deformans.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The lidocaine patch 5% was generally well tolerated and no patients discontinued due to treatment-related adverse events." | 6.71 | Topical lidocaine patch 5% may target a novel underlying pain mechanism in osteoarthritis. ( Burch, F; Codding, C; Galer, BS; Gammaitoni, AR; Patel, N; Sheldon, E, 2004) |
| "Diclofenac was highly effective in both tests on day 3, while on day 20 it induced a less pronounced decrease in the Knee-Bend score and was ineffective in the CatWalk test." | 5.38 | Analgesic effects of lidocaine, morphine and diclofenac on movement-induced nociception, as assessed by the Knee-Bend and CatWalk tests in a rat model of osteoarthritis. ( Adães, S; Castro-Lopes, JM; Ferreira-Gomes, J; Mendonça, M, 2012) |
| " We examined the utility of the Neuropathic Pain Scale (NPS) for assessing changes in pain qualities after open label lidocaine patch 5% in 3 samples of patients: patients with peripheral neuropathic pain, low back pain, and osteoarthritis." | 5.11 | Assessment of pain quality in chronic neuropathic and nociceptive pain clinical trials with the Neuropathic Pain Scale. ( Dworkin, RH; Galer, BS; Gammaitoni, AR; Jensen, MP; Olaleye, DO; Oleka, N, 2005) |
| ": To examine whether lidocaine cytotoxicity to chondrocytes has been implicated in the development of osteoarthritis of the zygapophysial joints." | 3.75 | Lidocaine cytotoxicity to the zygapophysial joints in rabbits: changes in cell viability and proteoglycan metabolism in vitro. ( Baba, H; Kobayashi, S; Kubota, M; Meir, A; Miyazaki, T; Shimada, S; Takeno, K; Urban, J, 2009) |
| "The lidocaine patch 5% was generally well tolerated and no patients discontinued due to treatment-related adverse events." | 2.71 | Topical lidocaine patch 5% may target a novel underlying pain mechanism in osteoarthritis. ( Burch, F; Codding, C; Galer, BS; Gammaitoni, AR; Patel, N; Sheldon, E, 2004) |
| " In order to ensure that intra-articular lidocaine is safe to use, treatments aimed at mitigating chondrocyte death have recently been investigated." | 1.48 | Protective effects of platelet-rich plasma against lidocaine cytotoxicity on canine articular chondrocytes. ( Bianchini, E; Buratta, S; Chiaradia, E; Di Meo, A; Floridi, C; Mancini, F; Moscati, L; Pepe, M; Pistilli, A; Stabile, A, 2018) |
| "Osteoarthritis is the most common form of arthritis and includes manifestations of both nociceptive and neuropathic mechanisms." | 1.40 | Osteoarthritis pain has a significant neuropathic component: an exploratory in vivo patient model. ( Ashford, RL; Dimitroulas, T; Duarte, RV; Kitas, GD; Raphael, JH; Southall, JL; Sparkes, E, 2014) |
| "This syndrome is usually related to anatomic variants (involving the bone structures, fibrous bands, or muscles and tendons)." | 1.38 | Supraclavicular nerve entrapment syndrome. ( Bruyère, PJ; Courtois, AC; Crielaard, JM; Douchamps, F, 2012) |
| "Whether ongoing pain is present in this model is unknown." | 1.38 | Afferent drive elicits ongoing pain in a model of advanced osteoarthritis. ( Brion, T; Davis, P; Dussor, GO; King, T; Liu, P; Okun, A; Ossipov, MH; Porreca, F; Remeniuk, B; Ren, J; Xie, J, 2012) |
| "Diclofenac was highly effective in both tests on day 3, while on day 20 it induced a less pronounced decrease in the Knee-Bend score and was ineffective in the CatWalk test." | 1.38 | Analgesic effects of lidocaine, morphine and diclofenac on movement-induced nociception, as assessed by the Knee-Bend and CatWalk tests in a rat model of osteoarthritis. ( Adães, S; Castro-Lopes, JM; Ferreira-Gomes, J; Mendonça, M, 2012) |
| "Anserine bursitis is commonly found in Koreans with OA of the knee, and its presence is unrelated to age, sex, and radiographic severity." | 1.31 | Anserine bursitis in patients with osteoarthritis of the knee. ( Han, SW; Kang, I, 2000) |
| "The occipital pain and headache of cervical arthritis also often respond to injection of 2 to 3 ml of long-acting anesthetic into the greater and lesser occipital nerves at the sites where they pierce the trapezius." | 1.26 | Relieving pain with nerve blocks. ( Carron, H, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 18 (46.15) | 18.7374 |
| 1990's | 3 (7.69) | 18.2507 |
| 2000's | 8 (20.51) | 29.6817 |
| 2010's | 7 (17.95) | 24.3611 |
| 2020's | 3 (7.69) | 2.80 |
| Authors | Studies |
|---|---|
| Moser, LB | 1 |
| Bauer, C | 1 |
| Jeyakumar, V | 1 |
| Niculescu-Morzsa, EP | 1 |
| Nehrer, S | 1 |
| Backhouse, MR | 1 |
| Halstead, J | 1 |
| Roddy, E | 1 |
| Dhukaram, V | 1 |
| Chapman, A | 1 |
| Arnold, S | 1 |
| Bruce, J | 1 |
| Mc Colgan, R | 1 |
| Dalton, DM | 1 |
| O'Sullivan, HP | 1 |
| Sproule, JA | 1 |
| Malahias, MA | 1 |
| Roumeliotis, L | 1 |
| Nikolaou, VS | 1 |
| Chronopoulos, E | 1 |
| Sourlas, I | 1 |
| Babis, GC | 1 |
| Bianchini, E | 1 |
| Mancini, F | 1 |
| Di Meo, A | 1 |
| Stabile, A | 1 |
| Buratta, S | 1 |
| Moscati, L | 1 |
| Pistilli, A | 1 |
| Floridi, C | 1 |
| Pepe, M | 1 |
| Chiaradia, E | 1 |
| Duarte, RV | 1 |
| Raphael, JH | 1 |
| Dimitroulas, T | 1 |
| Sparkes, E | 1 |
| Southall, JL | 1 |
| Ashford, RL | 1 |
| Kitas, GD | 1 |
| Jahangiri, A | 1 |
| Moghaddam, FR | 1 |
| Najafi, S | 1 |
| Takeno, K | 1 |
| Kobayashi, S | 1 |
| Miyazaki, T | 1 |
| Shimada, S | 1 |
| Kubota, M | 1 |
| Meir, A | 1 |
| Urban, J | 1 |
| Baba, H | 1 |
| Douchamps, F | 1 |
| Courtois, AC | 1 |
| Bruyère, PJ | 1 |
| Crielaard, JM | 1 |
| Okun, A | 1 |
| Liu, P | 1 |
| Davis, P | 1 |
| Ren, J | 1 |
| Remeniuk, B | 1 |
| Brion, T | 1 |
| Ossipov, MH | 1 |
| Xie, J | 1 |
| Dussor, GO | 1 |
| King, T | 1 |
| Porreca, F | 1 |
| Ferreira-Gomes, J | 1 |
| Adães, S | 1 |
| Mendonça, M | 1 |
| Castro-Lopes, JM | 1 |
| LAURENT, G | 1 |
| COMPERE, EL | 1 |
| Galer, BS | 3 |
| Sheldon, E | 1 |
| Patel, N | 1 |
| Codding, C | 1 |
| Burch, F | 1 |
| Gammaitoni, AR | 3 |
| Jensen, MP | 2 |
| Dworkin, RH | 2 |
| Olaleye, DO | 2 |
| Oleka, N | 1 |
| Rabago, D | 1 |
| Best, TM | 1 |
| Beamsley, M | 1 |
| Patterson, J | 1 |
| Stitik, TP | 1 |
| Altschuler, E | 1 |
| Foye, PM | 1 |
| Tantó, Z | 1 |
| Molnár, L | 1 |
| Kálózdi, T | 1 |
| Maros, M | 1 |
| Várhelyi, M | 1 |
| Mund-Hoym, WD | 1 |
| Gu, ZY | 1 |
| Wu, HL | 1 |
| Wu, QL | 1 |
| Cao, ZQ | 1 |
| Zhang, YX | 1 |
| Kang, I | 1 |
| Han, SW | 1 |
| Waxman, J | 1 |
| Goel, TC | 1 |
| Carron, H | 1 |
| Clarke, AM | 1 |
| Matthews, JG | 1 |
| Lark, MR | 1 |
| Gangarosa, LP | 1 |
| Konsens, RM | 1 |
| Seitz, WH | 1 |
| Voleník, O | 1 |
| Nilsson, G | 1 |
| Abrahamsen, D | 1 |
| Sadowska-Wrõblewska, M | 1 |
| Steinberg, MD | 1 |
| Beck, O | 1 |
| Chitil, W | 1 |
| Ortner, H | 1 |
| Schopen, RD | 1 |
| Iser, H | 1 |
| Marmor, L | 1 |
| Peter, JB | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Which is More Effective: Prolotherapy or Paraffin Waxes for Hand Ostearthritis[NCT03839108] | 42 participants (Actual) | Interventional | 2018-12-14 | Completed | |||
| Diode Laser as a Biomarker for Neuropathic Pain of Peripheral Origin.[NCT06030297] | 301 participants (Anticipated) | Interventional | 2022-11-01 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for lidocaine and Osteoarthritis
| Article | Year |
|---|---|
A systematic review of prolotherapy for chronic musculoskeletal pain.
Topics: Anesthetics, Local; Chronic Disease; Glucose; Humans; Injections; Lidocaine; Low Back Pain; Musculos | 2005 |
Pharmacotherapy of osteoarthritis.
Topics: Acetaminophen; Administration, Topical; Analgesics; Anesthetics, Local; Capsaicin; Delayed-Action Pr | 2006 |
[Drug therapy in degenerative joint diseases].
Topics: Animals; Cartilage, Articular; Humans; Hydrocortisone; Indomethacin; Lidocaine; Osteoarthritis; Pyra | 1971 |
8 trials available for lidocaine and Osteoarthritis
| Article | Year |
|---|---|
Platelet-Rich Plasma versus Corticosteroid Intra-Articular Injections for the Treatment of Trapeziometacarpal Arthritis: A Prospective Randomized Controlled Clinical Trial.
Topics: Adrenal Cortex Hormones; Carpometacarpal Joints; Female; Humans; Injections, Intra-Articular; Lidoca | 2021 |
Hypertonic dextrose versus corticosteroid local injection for the treatment of osteoarthritis in the first carpometacarpal joint: a double-blind randomized clinical trial.
Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Local; Anti-Inflammatory Agents; Carpometacarpal Joints | 2014 |
Topical lidocaine patch 5% may target a novel underlying pain mechanism in osteoarthritis.
Topics: Administration, Cutaneous; Administration, Topical; Anesthetics, Local; Female; Humans; Lidocaine; M | 2004 |
Assessment of pain quality in chronic neuropathic and nociceptive pain clinical trials with the Neuropathic Pain Scale.
Topics: Administration, Cutaneous; Adult; Aged; Analysis of Variance; Anesthetics, Local; Clinical Trials as | 2005 |
Symptom profiles differ in patients with neuropathic versus non-neuropathic pain.
Topics: Administration, Topical; Adult; Aged; Anesthetics, Local; Diabetic Neuropathies; Female; Humans; Lid | 2007 |
Intra-arterial use of No-Spa+lidocaine in coxarthrosis.
Topics: Clinical Trials as Topic; Hip Joint; Humans; Injections, Intra-Arterial; Lidocaine; Osteoarthritis; | 1982 |
The effect of intra-articular irrigation injection therapy on osteoarthrosis of the temporomandibular joint.
Topics: Adult; Chi-Square Distribution; Female; Humans; Injections, Intra-Articular; Lidocaine; Male; Middle | 1998 |
[A contribution to the combined physical and drug therapy of arthroses].
Topics: Aminopyrine; Clinical Trials as Topic; Diathermy; Humans; Lidocaine; Osteoarthritis; Prednisolone; S | 1965 |
28 other studies available for lidocaine and Osteoarthritis
| Article | Year |
|---|---|
Hyaluronic Acid as a Carrier Supports the Effects of Glucocorticoids and Diminishes the Cytotoxic Effects of Local Anesthetics in Human Articular Chondrocytes In Vitro.
Topics: Anesthetics, Local; Bupivacaine; Cell Survival; Cells, Cultured; Chondrocytes; Drug Therapy, Combina | 2021 |
A multi-professional survey of UK practice in the use of intra-articular corticosteroid injection for symptomatic first metatarsophalangeal joint osteoarthritis.
Topics: Adrenal Cortex Hormones; Anesthetics, Local; Cross-Sectional Studies; Humans; Injections, Intra-Arti | 2023 |
The prescription of lidocaine patches in osteoarthritis-a complete audit cycle.
Topics: Aged; Anesthetics, Local; Commission on Professional and Hospital Activities; Female; Humans; Lidoca | 2019 |
Protective effects of platelet-rich plasma against lidocaine cytotoxicity on canine articular chondrocytes.
Topics: Anesthetics, Local; Animals; Cell Survival; Chondrocytes; Cytoprotection; Dog Diseases; Dogs; Inject | 2018 |
Osteoarthritis pain has a significant neuropathic component: an exploratory in vivo patient model.
Topics: Adult; Aged; Anesthetics, Local; Arthralgia; Female; Humans; Infusions, Intravenous; Lidocaine; Male | 2014 |
Lidocaine cytotoxicity to the zygapophysial joints in rabbits: changes in cell viability and proteoglycan metabolism in vitro.
Topics: Analysis of Variance; Animals; Cartilage, Articular; Cell Count; Cell Survival; Cells, Cultured; Cho | 2009 |
Supraclavicular nerve entrapment syndrome.
Topics: Analgesics; Antirheumatic Agents; Brachial Plexus; Clavicle; Humans; Lidocaine; Male; Middle Aged; N | 2012 |
Afferent drive elicits ongoing pain in a model of advanced osteoarthritis.
Topics: Afferent Pathways; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Injections, In | 2012 |
Analgesic effects of lidocaine, morphine and diclofenac on movement-induced nociception, as assessed by the Knee-Bend and CatWalk tests in a rat model of osteoarthritis.
Topics: Administration, Oral; Analgesics; Animals; Arthralgia; Diclofenac; Disease Models, Animal; Injection | 2012 |
[RESULTS OF A MEDICAL TREATMENT OF MUSCULAR DYSTONY ACCOMPANYING COXARTHROSIS].
Topics: Anesthetics; Anesthetics, Local; Hip; Humans; Lidocaine; Muscular Diseases; Osteoarthritis; Osteoart | 1964 |
THE PAINFUL SHOULDER.
Topics: Arthritis; Bursitis; Drug Therapy; Humans; Hydrocortisone; Joints; Lidocaine; Osteoarthritis; Pain; | 1964 |
A patch for osteoarthritis relief.
Topics: Administration, Cutaneous; Anesthetics, Local; Humans; Lidocaine; Middle Aged; Osteoarthritis | 2005 |
[The treatment of hip and knee joint arthroses].
Topics: Adult; Aged; Arthritis; Drug Therapy, Combination; Female; Glucosamine; Hip Joint; Humans; Knee Join | 1980 |
Anserine bursitis in patients with osteoarthritis of the knee.
Topics: Anesthetics, Local; Anti-Inflammatory Agents; Bursitis; Female; Humans; Injections; Knee; Korea; Lid | 2000 |
Acromioclavicular disease in rheumatologic practice--the forgotten joint.
Topics: Acromioclavicular Joint; Female; Humans; Injections, Intra-Articular; Lidocaine; Male; Middle Aged; | 1977 |
Injection treatment for pain in osteo-arthrosis of knee joint.
Topics: Aged; Female; Humans; Knee Joint; Lidocaine; Male; Middle Aged; Osteoarthritis; Palliative Care | 1977 |
Relieving pain with nerve blocks.
Topics: Acute Disease; Aged; Back Pain; Bursitis; Humans; Intervertebral Disc; Joint Diseases; Lidocaine; Mi | 1978 |
Osteoarthritis of the fabella: a fourth knee compartment?
Topics: Aged; Humans; Injections, Intra-Articular; Knee Joint; Lidocaine; Male; Osteoarthritis; Radiography; | 1991 |
Iontophoresis: an effective modality for the treatment of inflammatory disorders of the temporomandibular joint and myofascial pain.
Topics: Adult; Discitis; Epinephrine; Facial Pain; Female; Humans; Inflammation; Iontophoresis; Joint Disloc | 1990 |
Post-traumatic arthrosis of the index carpometacarpal joint. A rationale for treatment and report of two cases.
Topics: Adult; Arthrodesis; Chronic Disease; Female; Humans; Lidocaine; Male; Metacarpus; Methylprednisolone | 1987 |
[Differential diagnosis and rational therapy of humero-scapular periarthritis and omarthritis].
Topics: Diagnosis, Differential; Humans; Hydrocortisone; Joint Diseases; Lidocaine; Osteoarthritis; Shoulder | 1974 |
Lameness and pathologic changes in the distal joints and the phalanges of the standardbred horse. A correlative study.
Topics: Animals; Equipment and Supplies; Female; Forelimb; Fractures, Bone; Gait; Hindlimb; Hoof and Claw; H | 1973 |
Letter: Therapy of osteoarthritis of the great toe.
Topics: Female; Humans; Hyaluronoglucosaminidase; Lidocaine; Osteoarthritis | 1973 |
Therapy of osteoarthritis of the great toe and hallux rigidus.
Topics: Drug Synergism; Female; Hallux; Humans; Hyaluronoglucosaminidase; Injections; Lidocaine; Male; Osteo | 1971 |
[The effectiveness of the protease inhibitor Contrykal in the drug therapy of arthrosis deformans].
Topics: Aprotinin; Hip Joint; Humans; Injections, Intra-Articular; Injections, Intramuscular; Knee Joint; Li | 1971 |
[Dexamonosone as a rheuma therapeutic agent].
Topics: Anti-Inflammatory Agents; Arm; Arthritis; Brachial Plexus Neuritis; Dosage Forms; Erythema Nodosum; | 1970 |
[Treatment of rheumatic diseases with Supertendin].
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Dexamethasone; Humans; Joint Diseases; Lidocaine; O | 1968 |
Osteoarthritis of the carpometacarpal joint of the thumb.
Topics: Anti-Inflammatory Agents; Arthrodesis; Arthroplasty; Female; Humans; Injections, Intra-Articular; Li | 1969 |