Page last updated: 2024-10-28

lidocaine and Osteoarthritis, Knee

lidocaine has been researched along with Osteoarthritis, Knee in 34 studies

Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.

Osteoarthritis, Knee: Noninflammatory degenerative disease of the knee joint consisting of three large categories: conditions that block normal synchronous movement, conditions that produce abnormal pathways of motion, and conditions that cause stress concentration resulting in changes to articular cartilage. (Crenshaw, Campbell's Operative Orthopaedics, 8th ed, p2019)

Research Excerpts

ExcerptRelevanceReference
"To determine the impact of the lidocaine patch 5% on distinct pain qualities associated with osteoarthritis (OA) through use of the Neuropathic Pain Scale (NPS), an assessment tool designed to assess intensity of various pain qualities (i."9.11Lidocaine patch 5% and its positive impact on pain qualities in osteoarthritis: results of a pilot 2-week, open-label study using the Neuropathic Pain Scale. ( Argoff, CE; Galer, BS; Gammaitoni, AR; Jensen, MP; Onawola, R, 2004)
" The purpose of this study was to compare the effects of intra-articular (IA) administration of tranexamic acid (TXA), an anti-fibrinolytic commonly used in TKA, and ALM chondroprotective solution on postoperative inflammation and joint tissue healing in a rat model of knee implant surgery."8.02Comparison of intra-articular administration of adenosine, lidocaine and magnesium solution and tranexamic acid for alleviating postoperative inflammation and joint fibrosis in an experimental model of knee arthroplasty. ( Biros, E; Dlaska, C; Dobson, GP; Hazratwala, K; Letson, HL; McEwen, P; Morris, JL; Wilkinson, M, 2021)
" Therefore, we designed a randomized, double-blind, placebo-controlled clinical trial with a 2-period crossover design to study (1) behavioral incentives to promote exercise and (2) corticosteroid injections to reduce pain and improve function in patients with KOA when compared to lidocaine only."5.51Protocol for a multi-center randomized controlled trial to evaluate the benefits of exercise incentives and corticosteroid injections in osteoarthritis of the knee (MOVE-OK). ( Baker, JF; Doherty, C; England, BR; Kerr, G; Leach, W; Neogi, T; Ogdie, A; Olave, M; Quinones, M; Scanzello, CR; White, D; Wysham, K, 2022)
"To determine the impact of the lidocaine patch 5% on distinct pain qualities associated with osteoarthritis (OA) through use of the Neuropathic Pain Scale (NPS), an assessment tool designed to assess intensity of various pain qualities (i."5.11Lidocaine patch 5% and its positive impact on pain qualities in osteoarthritis: results of a pilot 2-week, open-label study using the Neuropathic Pain Scale. ( Argoff, CE; Galer, BS; Gammaitoni, AR; Jensen, MP; Onawola, R, 2004)
" In patients with neuropathic pain, topical forms of both capsaicin and lidocaine have been shown to be useful in the treatment of postherpetic neuralgia and diabetic peripheral neuropathic pain."4.89Topical therapies in the management of chronic pain. ( Galluzzi, KE; Stanos, SP, 2013)
" The purpose of this study was to compare the effects of intra-articular (IA) administration of tranexamic acid (TXA), an anti-fibrinolytic commonly used in TKA, and ALM chondroprotective solution on postoperative inflammation and joint tissue healing in a rat model of knee implant surgery."4.02Comparison of intra-articular administration of adenosine, lidocaine and magnesium solution and tranexamic acid for alleviating postoperative inflammation and joint fibrosis in an experimental model of knee arthroplasty. ( Biros, E; Dlaska, C; Dobson, GP; Hazratwala, K; Letson, HL; McEwen, P; Morris, JL; Wilkinson, M, 2021)
" Joint pain relief from lidocaine administration could be reliably tracked over its brief acting time course."3.79Intra-articular anaesthesia mitigates established pain in experimental osteoarthritis: a preliminary study of gait impulse redistribution as a biomarker of analgesia pharmacodynamics. ( Bertram, JE; Gutmann, A; Hurtig, M; Matyas, JR; Randev, J, 2013)
" We analyzed data from 5 open-label clinical trials of lidocaine patch 5% in osteoarthritis knee pain and chronic low back pain that were 2 to 12 weeks in duration."3.77Treatment satisfaction in osteoarthritis and chronic low back pain: the role of pain, physical and emotional functioning, sleep, and adverse events. ( Dworkin, RH; Galer, BS; Gammaitoni, AR; Gould, E; Jensen, MP; Jones, BA; Xiang, Q, 2011)
"The effects of an analgesic treatment (lidocaine patches) on brain activity in chronic low back pain (CBP) and in knee osteoarthritis (OA) were investigated using serial fMRI (contrasting fMRI between before and after two weeks of treatment)."3.74A preliminary fMRI study of analgesic treatment in chronic back pain and knee osteoarthritis. ( Apkarian, AV; Baliki, MN; Geha, PY; Harden, N; Jabakhanji, R; Schnitzer, TJ, 2008)
"Ultrasound-guided GNB, when combined with a local anesthetic and corticosteroid, can provide short-term pain relief."2.87Ultrasound-Guided Genicular Nerve Block for Knee Osteoarthritis: A Double-Blind, Randomized Controlled Trial of Local Anesthetic Alone or in Combination with Corticosteroid. ( Choi, SS; Choi, WJ; Kim, DH; Lee, IG; Lee, SH; Seo, DK; Shin, JW; Yoon, SH, 2018)
"Patients with osteoarthritis of the knee are at risk for poorer outcomes after arthroscopic meniscectomy."2.74A randomized, prospective, double-blind study to investigate the effectiveness of adding DepoMedrol to a local anesthetic injection in postmeniscectomy patients with osteoarthritis of the knee. ( Cole, BJ; Kang, RW; Kirk, SS; Koyonos, L; Lewis, PB; McNickle, AG; Yanke, AB, 2009)
"Joint pain is a primary symptom in knee osteoarthritis (OA), but the effect of pain and pain relief on the knee joint mechanics of walking is not clear."1.33Increased joint loads during walking--a consequence of pain relief in knee osteoarthritis. ( Alkjaer, T; Bliddal, H; Danneskiold-Samsøe, B; Graven-Nielsen, T; Henriksen, M; Lund, H; Simonsen, EB, 2006)

Research

Studies (34)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (2.94)18.2507
2000's11 (32.35)29.6817
2010's18 (52.94)24.3611
2020's4 (11.76)2.80

Authors

AuthorsStudies
Morris, JL1
Letson, HL1
McEwen, P1
Biros, E1
Dlaska, C1
Hazratwala, K1
Wilkinson, M1
Dobson, GP1
Leach, W1
Doherty, C1
Olave, M1
England, BR1
Wysham, K1
Kerr, G1
Quinones, M1
Ogdie, A1
White, D1
Neogi, T1
Scanzello, CR1
Baker, JF1
Xu, W1
Xiao, Y1
Zhao, M1
Zhu, J1
Wang, Y1
Wang, W1
Wang, P1
Meng, H1
Martínez-Barro, D1
Rivera-Bello, JD1
Cruz-López, JM1
Hernández-Amaro, H1
Rojano-Mejía, D1
Allen, J2
Imbert, I2
Havelin, J2
Henderson, T1
Stevenson, G1
Liaw, L1
King, T2
Lee, DH1
Lee, MY1
Kwack, KS1
Yoon, SH2
Miletic, I1
Agten, C1
Sutter, R1
Pfirrmann, C1
Peterson, C1
Kim, DH1
Choi, SS1
Lee, SH1
Seo, DK1
Lee, IG1
Choi, WJ1
Shin, JW1
Klocke, R2
Levasseur, K1
Kitas, GD1
Smith, JP1
Hirsch, G2
Hamza, M1
Nadeem, IA1
Fatima, N1
Conger, A1
McCormick, ZL1
Henrie, AM1
Park, KD1
Ahn, JK1
Lee, SC2
Lee, J1
Kim, J1
Park, Y2
Matyas, JR1
Gutmann, A1
Randev, J1
Hurtig, M1
Bertram, JE1
Stanos, SP1
Galluzzi, KE1
Ertürk, C1
Altay, MA1
Altay, N1
Kalender, AM1
Öztürk, İA1
Cormier, J1
Porreca, F1
Soriano-Maldonado, A1
Klokker, L1
Bartholdy, C1
Bandak, E1
Ellegaard, K1
Bliddal, H2
Henriksen, M2
Eker, HE1
Cok, OY1
Aribogan, A1
Arslan, G1
O'Neill, TW1
Kitas, G1
Sinha, A1
Baliki, MN1
Geha, PY1
Jabakhanji, R1
Harden, N1
Schnitzer, TJ1
Apkarian, AV1
Kivitz, A1
Fairfax, M1
Sheldon, EA1
Xiang, Q2
Jones, BA2
Gammaitoni, AR3
Gould, EM1
Koyonos, L1
Yanke, AB1
McNickle, AG1
Kirk, SS1
Kang, RW1
Lewis, PB1
Cole, BJ1
Loughnan, TE1
Taverner, MG1
Webb, A1
Dworkin, RH1
Jensen, MP2
Gould, E1
Galer, BS2
Dumais, R1
Benoit, C1
Dumais, A1
Babin, L1
Bordage, R1
de Arcos, C1
Allard, J1
Bélanger, M1
Jang, SH1
Lee, JH1
Nam, SH1
Cho, KR1
Burch, F1
Codding, C1
Patel, N1
Sheldon, E1
Neafsey, PJ1
Onawola, R1
Argoff, CE1
Simonsen, EB1
Alkjaer, T1
Lund, H1
Graven-Nielsen, T1
Danneskiold-Samsøe, B1
Lockman, LE1
McCarberg, B1
D'Arcy, Y1
Dickson, DJ1
Wohlrab, D1
Lebek, S1
Krüger, T1
Reichel, H1

Clinical Trials (11)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Pragmatic Trial to Determine the Benefit of Behaviorally Enhanced Exercise Incentives and Corticosteroid Injections in Osteoarthritis of the Knee[NCT05035810]Phase 3240 participants (Anticipated)Interventional2022-03-14Recruiting
Minimally Invasive Knee Osteoarthritis Pain Control Via Adductor Canal Block Versus Intra-articular Steroid and Lignocaine Injection : a Single-blinded Controlled Trial[NCT04264481]64 participants (Actual)Interventional2019-07-12Completed
A Randomized Controlled Trial of Ultrasound Guided Knee Genicular Nerve Block and Anterior Femoral Cutaneous Nerve Block for Primary Total Knee Arthroplasty[NCT05980546]Phase 4244 participants (Anticipated)Interventional2023-06-07Recruiting
Autologous Conditioned Serum: Functional and Clinical Results Using a Novel Disease Modifying Agent for the Management of Knee Osteoarthritis[NCT03850080]Phase 2/Phase 315 participants (Actual)Interventional2017-10-06Completed
Radiofrequency Ablation and Steroid Versus Steroid Alone for Relief of Pain in Patients With Advanced Knee and Hip Osteoarthritis[NCT05490355]80 participants (Anticipated)Interventional2022-12-20Recruiting
Trial Evaluating multimOdal toPical Cream In CompArison to pLacebo (TOPICAL)[NCT03199417]Phase 2/Phase 350 participants (Actual)Interventional2017-05-01Terminated (stopped due to Terminated prematurely due to feasibility issues with rate of recruitment)
Corticosteriods vs. Saline vs. Air Placebo Intra-articular Injections for Knee Osteoarthritis: A Single Blinded Prospective Randomized Trial[NCT02995083]Early Phase 10 participants (Actual)Interventional2017-06-30Withdrawn (stopped due to Study deemed not feasible)
Brain Imaging of Lidoderm for Chronic Back Pain[NCT01515540]Phase 438 participants (Actual)Interventional2004-01-31Completed
Efficacy of Intra-operative Subacromial Corticosteroid Injections on Surgical Outcomes After Arthroscopic Shoulder Surgery[NCT02867904]Phase 412 participants (Actual)Interventional2016-03-31Terminated (stopped due to It was difficult to recruit patients to get the appropriate sample size.)
Treatment of Temporomandibular Dysfunction With Hypertonic Dextrose Injection: A Randomised Clinical Trial of Efficacy[NCT01706172]Phase 2/Phase 342 participants (Actual)Interventional2013-01-31Completed
Efficacy Evaluation of Intra-articular Hyaluronic Acid (Sinovial®) vs Synvisc® in the Treatment of Symptomatic Knee Osteoarthritis. A Double-blind, Controlled, Randomised, Parallel-group Non-inferiority Study[NCT00556608]Phase 4381 participants (Actual)Interventional2007-11-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

"Pain Intensity on a Visual Analog Scale (VAS) The Scale Had Values From 0-100, Where 0 Represents no Pain and 100 Was the Worst Pain Imaginable."

"the primary hypothesis was that the lidoderm 5% patch was expected to decrease pain intensity post treatment greater than placebo patch.~A lower value on the 0-100 scale is considered to represent less pain. Higher values represent more pain. Greater than 20%-30% decrease in pain is considered clinically meaningful." (NCT01515540)
Timeframe: 2 weeks

Interventionpeak pain intensity (Mean)
Lidocaine51.0
Control51.6

Reviews

4 reviews available for lidocaine and Osteoarthritis, Knee

ArticleYear
Topical therapies in the management of chronic pain.
    Postgraduate medicine, 2013, Volume: 125, Issue:4 Suppl 1

    Topics: Administration, Cutaneous; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Capsaicin; C

2013
Patching pain with lidocaine: new uses for the lidocaine 5% patch.
    Home healthcare nurse, 2004, Volume: 22, Issue:8

    Topics: Administration, Cutaneous; Anesthetics, Local; Back Pain; Humans; Lidocaine; Neuralgia; Osteoarthrit

2004
Target pain with topical peripheral analgesics.
    The Nurse practitioner, 2007, Volume: 32, Issue:7

    Topics: Administration, Topical; Aged; Analgesics; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroid

2007
A rational approach to osteoarthritis.
    The Practitioner, 1997, Volume: 241, Issue:1581

    Topics: Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Humans; Injections, Intra-Articular

1997

Trials

14 trials available for lidocaine and Osteoarthritis, Knee

ArticleYear
Protocol for a multi-center randomized controlled trial to evaluate the benefits of exercise incentives and corticosteroid injections in osteoarthritis of the knee (MOVE-OK).
    Trials, 2022, Jul-27, Volume: 23, Issue:1

    Topics: Adrenal Cortex Hormones; Aged; Exercise; Humans; Lidocaine; Multicenter Studies as Topic; Osteoarthr

2022
[Functionality/isokinetic work of quadriceps in patients with gonarthrosis managed with prolotherapy].
    Revista medica del Instituto Mexicano del Seguro Social, 2023, Nov-06, Volume: 61, Issue:6

    Topics: Exercise Therapy; Humans; Lidocaine; Osteoarthritis, Knee; Pain; Prolotherapy; Treatment Outcome

2023
Ultrasound-Guided Genicular Nerve Block for Knee Osteoarthritis: A Double-Blind, Randomized Controlled Trial of Local Anesthetic Alone or in Combination with Corticosteroid.
    Pain physician, 2018, Volume: 21, Issue:1

    Topics: Adrenal Cortex Hormones; Aged; Anesthetics, Local; Double-Blind Method; Female; Humans; Lidocaine; M

2018
Comparison of ultrasound-guided intra-articular injections by long axis in plane approach on three different sites of the knee.
    American journal of physical medicine & rehabilitation, 2013, Volume: 92, Issue:11

    Topics: Aged; Anesthetics, Local; Contrast Media; Female; Glucocorticoids; Humans; Injections, Intra-Articul

2013
Will a single periarticular lidocaine-corticosteroid injection improve the clinical efficacy of intraarticular hyaluronic acid treatment of symptomatic knee osteoarthritis?
    Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA, 2016, Volume: 24, Issue:11

    Topics: Activities of Daily Living; Aged; Anesthetics, Local; Anti-Inflammatory Agents; Betamethasone; Drug

2016
Intra-Articular Corticosteroids in Addition to Exercise for Reducing Pain Sensitivity in Knee Osteoarthritis: Exploratory Outcome from a Randomized Controlled Trial.
    PloS one, 2016, Volume: 11, Issue:2

    Topics: Adrenal Cortex Hormones; Aged; Anesthetics, Local; Exercise Therapy; Female; Humans; Injections, Int

2016
The efficacy of intra-articular lidocaine administration in chronic knee pain due to osteoarthritis: A randomized, double-blind, controlled study.
    Anaesthesia, critical care & pain medicine, 2017, Volume: 36, Issue:2

    Topics: Aged; Anesthetics, Local; Chronic Pain; Double-Blind Method; Female; Humans; Injections, Intra-Artic

2017
The efficacy of intra-articular lidocaine administration in chronic knee pain due to osteoarthritis: A randomized, double-blind, controlled study.
    Anaesthesia, critical care & pain medicine, 2017, Volume: 36, Issue:2

    Topics: Aged; Anesthetics, Local; Chronic Pain; Double-Blind Method; Female; Humans; Injections, Intra-Artic

2017
The efficacy of intra-articular lidocaine administration in chronic knee pain due to osteoarthritis: A randomized, double-blind, controlled study.
    Anaesthesia, critical care & pain medicine, 2017, Volume: 36, Issue:2

    Topics: Aged; Anesthetics, Local; Chronic Pain; Double-Blind Method; Female; Humans; Injections, Intra-Artic

2017
The efficacy of intra-articular lidocaine administration in chronic knee pain due to osteoarthritis: A randomized, double-blind, controlled study.
    Anaesthesia, critical care & pain medicine, 2017, Volume: 36, Issue:2

    Topics: Aged; Anesthetics, Local; Chronic Pain; Double-Blind Method; Female; Humans; Injections, Intra-Artic

2017
Comparison of the effectiveness and tolerability of lidocaine patch 5% versus celecoxib for osteoarthritis-related knee pain: post hoc analysis of a 12 week, prospective, randomized, active-controlled, open-label, parallel-group trial in adults.
    Clinical therapeutics, 2008, Volume: 30, Issue:12

    Topics: Administration, Cutaneous; Administration, Oral; Adult; Aged; Anesthetics, Local; Arthralgia; Celeco

2008
A randomized, prospective, double-blind study to investigate the effectiveness of adding DepoMedrol to a local anesthetic injection in postmeniscectomy patients with osteoarthritis of the knee.
    The American journal of sports medicine, 2009, Volume: 37, Issue:6

    Topics: Adult; Aged; Anesthetics; Anesthetics, Local; Anti-Inflammatory Agents; Arthroscopy; Chondromalacia

2009
Randomized, double blinded comparative trial of intradermal injections of lignocaine versus N-saline around the knee to relieve pain in patients awaiting total knee replacement.
    The Clinical journal of pain, 2009, Volume: 25, Issue:4

    Topics: Anesthetics, Local; Arthralgia; Arthroplasty, Replacement, Knee; Double-Blind Method; Female; Humans

2009
Effect of regenerative injection therapy on function and pain in patients with knee osteoarthritis: a randomized crossover study.
    Pain medicine (Malden, Mass.), 2012, Volume: 13, Issue:8

    Topics: Aged; Anesthetics, Local; Arthralgia; Cross-Over Studies; Exercise Therapy; Female; Follow-Up Studie

2012
Comparison of ultrasound (US)-guided intra-articular injections by in-plain and out-of-plain on medial portal of the knee.
    Rheumatology international, 2013, Volume: 33, Issue:8

    Topics: Aged; Drug Therapy, Combination; Female; Humans; Injections, Intra-Articular; Knee Joint; Lidocaine;

2013
Lidocaine patch 5% improves pain, stiffness, and physical function in osteoarthritis pain patients. A prospective, multicenter, open-label effectiveness trial.
    Osteoarthritis and cartilage, 2004, Volume: 12, Issue:3

    Topics: Administration, Cutaneous; Adult; Aged; Aged, 80 and over; Anesthetics, Local; Female; Humans; Lidoc

2004
Lidocaine patch 5% and its positive impact on pain qualities in osteoarthritis: results of a pilot 2-week, open-label study using the Neuropathic Pain Scale.
    Current medical research and opinion, 2004, Volume: 20 Suppl 2

    Topics: Administration, Cutaneous; Anesthetics, Local; Female; Humans; Lidocaine; Male; Middle Aged; Osteoar

2004

Other Studies

16 other studies available for lidocaine and Osteoarthritis, Knee

ArticleYear
Comparison of intra-articular administration of adenosine, lidocaine and magnesium solution and tranexamic acid for alleviating postoperative inflammation and joint fibrosis in an experimental model of knee arthroplasty.
    Journal of orthopaedic surgery and research, 2021, Dec-20, Volume: 16, Issue:1

    Topics: Adenosine; Administration, Intravenous; Animals; Antifibrinolytic Agents; Arthroplasty, Replacement,

2021
Effective Treatment of Knee Osteoarthritis Using a Nano-Enabled Drug Acupuncture Technology in Mice.
    Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2023, Volume: 10, Issue:28

    Topics: Acupuncture Therapy; Animals; Cyclodextrins; Lidocaine; Mice; Osteoarthritis, Knee; Proteomics; Tech

2023
Effects of Treadmill Exercise on Advanced Osteoarthritis Pain in Rats.
    Arthritis & rheumatology (Hoboken, N.J.), 2017, Volume: 69, Issue:7

    Topics: Anesthetics, Local; Animals; Arthralgia; Arthritis, Experimental; Behavior, Animal; Disease Models,

2017
Effect of adductor canal block on medial compartment knee pain in patients with knee osteoarthritis: Retrospective comparative study.
    Medicine, 2017, Volume: 96, Issue:12

    Topics: Aged; Anesthetics, Local; Anti-Inflammatory Agents; Arthralgia; Case-Control Studies; Female; Follow

2017
Relationship of Radiographic Osteoarthritis Severity with Treatment Outcomes after Imaging-Guided Knee Injections: A Prospective Outcomes Study.
    RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin, 2018, Volume: 190, Issue:2

    Topics: Adrenal Cortex Hormones; Arthrography; Cohort Studies; Fluoroscopy; Humans; Injections, Intra-Articu

2018
Cartilage turnover and intra-articular corticosteroid injections in knee osteoarthritis.
    Rheumatology international, 2018, Volume: 38, Issue:3

    Topics: Adrenal Cortex Hormones; Aged; Anesthetics, Local; Biomarkers; Bone Remodeling; Cartilage Oligomeric

2018
Localized Injection of Streptomycin, Kenacort and Lidocaine combination for Symptomatic Pain Management of Knee Osteoarthritis.
    JPMA. The Journal of the Pakistan Medical Association, 2018, Volume: 68, Issue:9

    Topics: Aged; Anesthetics, Local; Anti-Bacterial Agents; Anti-Inflammatory Agents; Female; Humans; Injection

2018
Pes Anserine Tendon Injury Resulting from Cooled Radiofrequency Ablation of the Inferior Medial Genicular Nerve.
    PM & R : the journal of injury, function, and rehabilitation, 2019, Volume: 11, Issue:11

    Topics: Aged; Anesthetics, Local; Catheter Ablation; Chronic Pain; Combined Modality Therapy; Female; Follow

2019
Intra-articular anaesthesia mitigates established pain in experimental osteoarthritis: a preliminary study of gait impulse redistribution as a biomarker of analgesia pharmacodynamics.
    Osteoarthritis and cartilage, 2013, Volume: 21, Issue:9

    Topics: Anesthetics, Local; Animals; Anterior Cruciate Ligament Injuries; Anti-Inflammatory Agents, Non-Ster

2013
Central Sensitization and Neuropathic Features of Ongoing Pain in a Rat Model of Advanced Osteoarthritis.
    The journal of pain, 2016, Volume: 17, Issue:3

    Topics: Analgesics; Animals; Arthralgia; Central Nervous System Sensitization; Disease Models, Animal; Dose-

2016
Accuracy of injection and short-term pain relief following intra-articular corticosteroid injection in knee osteoarthritis - an observational study.
    BMC musculoskeletal disorders, 2017, 01-26, Volume: 18, Issue:1

    Topics: Aged; Anatomic Landmarks; Anesthetics, Local; Female; Glucocorticoids; Humans; Injections, Intra-Art

2017
A preliminary fMRI study of analgesic treatment in chronic back pain and knee osteoarthritis.
    Molecular pain, 2008, Oct-25, Volume: 4

    Topics: Adult; Aged; Analgesia; Back Pain; Brain Mapping; Chronic Disease; Female; Gyrus Cinguli; Humans; Li

2008
Treatment satisfaction in osteoarthritis and chronic low back pain: the role of pain, physical and emotional functioning, sleep, and adverse events.
    The journal of pain, 2011, Volume: 12, Issue:4

    Topics: Anesthetics, Local; Chronic Disease; Clinical Trials as Topic; Female; Humans; Lidocaine; Low Back P

2011
Increased joint loads during walking--a consequence of pain relief in knee osteoarthritis.
    The Knee, 2006, Volume: 13, Issue:6

    Topics: Aged; Anesthetics, Local; Case-Control Studies; Gait; Humans; Injections, Intra-Articular; Knee Join

2006
Practice tips. Knee joint injections and aspirations: the triangle technique.
    Canadian family physician Medecin de famille canadien, 2006, Volume: 52, Issue:11

    Topics: Adjuvants, Immunologic; Anesthetics, Local; Biopsy, Fine-Needle; Glucocorticoids; Humans; Hyaluronic

2006
Influence of ion channels on the proliferation of human chondrocytes.
    Biorheology, 2002, Volume: 39, Issue:1-2

    Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4-Aminopyridine; 4,4'-Diisothiocyanostil

2002